• Journal of Microbiology and Biotechnology
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• 제20권1호
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• pp.78-81
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• 2010

Four compounds were isolated from the culture broth of Volvariella bombycina and they were identified as ergosta-4,6,8(14),22-tetraene-3-one (1), ergosterol peroxide (2), indole-3-carboxaldehyde (3), and indazole (4) by interpretation of spectroscopic data. Among them, compound 2 exhibited melanogenesis inhibitory effect in cultured B16 mouse melanoma cells.

• 한국버섯학회지
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• 제21권1호
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• pp.15-21
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• 2023

본 연구에서는 V. bombycina 자실체의 안정적인 대량생산에 기반되는 필수적인 균사체 생산을 위한 최적 배양조건을 구명하고자 하였다. V. bombycina 균사체의 효율적 배양을 위한 조건은 최적 배양온도는 30℃, pH 8.0, 탄소원 0.7% Soluble starch, 유기질소원 0.7% Soytone, 무기질소원 1.0% (NH₄)₂C₄H₄O₆, 아미노산 0.1% Cysteine, 유기산은 0.07% Lactic acid, 그리고 무기염류는 7 mM CaCl₂ 조건이었다. 새로이 명명한 SSNA V. bombycina의 최적 배지는 추후 V. bombycina의 재배에 널리 활용될 수 있을 것으로 판단된다. 본 연구 결과에 따라 선발된 배양조건으로 흰비단털버섯의 반경을 측정한 결과 37 mm/7days로 24 mm/7days로 측정된 대조군인 PDA 배지보다 균사생육이 빨랐다(Fig. 16, 17). 흰비단털버섯의 기본적인 적정 생육환경을 조사하여 확인된 실험 데이터는 흰비단털버섯 자실체 발생을 위한 흰비단털버섯의 역할을 규명하는데 기여할 것으로 판단된다.

• 생약학회지
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• 제17권1호
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• pp.39-48
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• 1986

To find antitumor components in the shake-cultured mycelia of Volvariella bombycina, the mycelia were extracted with hot water. After the extract was dialyzed and freeze-dried, a protein-polysaccharide fraction was obtained and examined for antitumor activity against the solid form of sarcoma 180 in ICR mice. It showed 60.3% inhibition ratio at a dose of 20mg/kg/day for 10 days. It was found to consist of a polysaccharide moiety and a protein moiety. After gel filtration on Sepharose 4B, Fraction B was obtained and showed the highest inhibition ratio of 71.1%. When the antitumor component was examined for immunopotentiating activity, it was found to increase the macrophage accumulation in the peritoneal cavity as well as the antibody production of the spleen cells of the mice.