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EFFECT OF PLATELET-RICH PLASMA ON AUTOGENOUS BONE GRAFT FOR BONE FORMATION IN RABBIT (가토 하악골 결손부의 자가골 이식시 혈소판 풍부혈장이 골형성 촉진에 미치는 영향에 관한 연구)

  • Jeon, Min-Su;Kim, Bo-Gyun;Song, Jun-Ho;Yeon, Byong-Moo;Lee, Young-Woo;Noh, Kyung-Lok;Kim, Da-Young;Pang, Ean-O;Kim, Jun-Hyun;Nam, Jeong-Hun;Gang, Tae-In;Lim, Sung-Chul;Park, Young-Ju
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.30 no.2
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    • pp.158-164
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    • 2008
  • Purpose : Recently, various materials were developed for enhancing bone formation capacity. Platelet rich plasma(PRP) is an autologous source with several growth factors and obtained by sequestering and concentrating platelets by gradient density centrifugation. This study was to evaluate the effect of PRP on healing of grafted bone. Materials and methods : Two blood samples were obtained and analysed for measuring platelet counts of normal blood and PRP. In experimental group, two defects of mandibular bone, 10mm in diameter and 4.0mm deep, were created in the mandible and immediately grafted with autogenous bone chips mixed with PRP. In control group, same bone defects were prepared and grafted with autogenous bone chips. Gelform was used for carrier of PRP. 2 weeks, 4 weeks, 8 weeks later, each group was evaluated with histologi-cal and histomorphometric analyses. Results : According to histological observation, experimental group was showed more anastomosing newly-formed woven bone having osteoblastic activation than control group. According to histomorphometric analysis, there were 9.11% more newly-formed bone volume in experimental group than control group at 2 weeks, 7.91% more at 4 weeks, 20.08% more at 8 weeks. Conclusion: Our results demonstrated PRP in autogenous bone graft could enhance the bone formation.

An Investigation into the Release of Chemical Oxygen Demand in Organic Filter Media (유기성 여재로부터 화학적 산소요구량 물질의 방출에 관한 연구)

  • Guerra, Heidi B.;Kim, Youngchul
    • Journal of Wetlands Research
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    • v.22 no.3
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    • pp.171-177
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    • 2020
  • To improve the nitrogen reduction capability of stormwater treatment systems subjected to intermittent saturation, organic materials are often added as filter media. However, these materials can be an additional source of organic carbon and increase the chemical oxygen demand (COD) in the outflow. In this study, different types of organic filter media were subjected to a batch leaching test to observe and quantify the release of COD. Results reveal that the initial pH of the tap water used for soaking which is 7.5-7.7 is conducive to the release of organics from the media to the leachate. The highest amount of COD released was observed in yard clippings and woodchip followed by compost and bark mulch. The leaching of organics also increased as the size of the media decreases due to higher surface area per volume. In addition, empirical regression analysis predicted that COD from these organic media will be exhausted from the material in 3-5 months to up to 26 months depending on the type of media. The results of this study can serve as a guide in estimating the potential release of COD in organic media in order to ensure their safe application in stormwater treatment facilities.

Quality Characteristics of Wet Noodles Added with Korean Paprika Powder (한국산 파프리카 분말을 첨가한 국수의 품질 특성)

  • Jeong, Chang-Ho;Kim, Jin-Hee;Cho, Jeong-Rai;Ahn, Cheol-Gun;Shim, Ki-Hwan
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.36 no.6
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    • pp.779-784
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    • 2007
  • This study investigated quality characteristics of wet noodles with addition of paprika powder prepared by different cultivars, freeze dried Special paprika powder (FDSP) and freeze dried Fiesta paprika powder (FDFP) at 0.5, 1.0 and 2.0% based on flour source, respectively. The wet noodles containing paprika powder exhibited higher values for cooked weight, volume, water absorption, and turbidity. When the amount of FDSP increased, the Hunter L (lightness) value of cooked noodles decreased but a (redness) value and b (yellowness) value increased. When the amount of FDFP increased, the Hunter L (lightness) and a (redness) value of cooked noodles decreased but b (yellowness) value increased. From textural properties measured by a texture analyzer, the noodles with paprika powder were significantly lower in hardness, cohesiveness, springiness, gumminess and chewiness than those of 100% wheat noodle. The results of sensory evaluation of cooked noodles containing paprika powder indicated that the cooked noodles with 1.0% paprika powder showed the highest value.

Comparative Analyses of Mass Marketing and Target Marketing Based on Price Elasticity and Production Cost (가격탄력성과 생산비용에 기초한 대량 마케팅과 표적시장 마케팅의 비교 분석)

  • Won, Jee Sung
    • Journal of Distribution Science
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    • v.11 no.4
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    • pp.61-72
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    • 2013
  • Purpose - It is widely accepted that the process of developing marketing strategy is composed of three steps: market segmentation, target market selection and positioning. However, mass marketing strategy based on cost reduction through economies of scale and standardized products, can be also an effective strategic option. Many marketing scholars including Theodore Levitt emphasize the importance of applying the mass production concept to various industries including service industries. Especially, in times of economic downturn, the capability of providing consumers with low-priced, value products can be an important source of competitive advantage, as well as the ability of providing high-priced premium products. Marketers should decide whether they will implement mass marketing strategy or target marketing strategy. The present study theoretically shows that firms should understand the target customers' price elasticity as well as the firm's cost structure in order to make such a strategic decision. Research design, data, and methodology - Instead of implementing an empirical study, this study provides a theoretical(mathematical) investigation on the effect of consumers' price elasticity on a firm's optimal price level, profit, sales volume, revenue, and cost. The results are mostly deduced from derivative calculations and several graphs are utilized to represent the results on the relationships between the variables under study. Results - The analytical results suggest that it is more profitable for a firm to adopt the segment/target marketing strategy (more specifically the differentiation strategy) when the degree of consumers' heterogeneity is high and the proportion of the fixed cost in the total cost is low. On the other hand, if the degree of consumers' heterogeneity is low and the fixed cost is high, it is better to adopt the mass marketing strategy or the cost leadership strategy. The strategy of concentrating on a single target market will be effective when consumers' needs are highly heterogeneous but the fixed cost is high. Any of the three types of generic strategies proposed my Porter(1980, 1985) can be applied when both the consumers' heterogeneity and the fixed cost are low. This study also proposes the contribution-margin-based method for developing the optimal pricing strategy. Conclusions - One of the primary roles of marketers is to find a proper compromise between the two conflicting goals of maximizing customer satisfaction and minimizing cost. In order to do so, he or she should understand the characteristics of the target customers as well as the cost structure of the firm. In addition to the theoretical analyses, this study discusses several business cases and explains how superior companies find the optimal compromise position between these two goals and dominate the market. One of the radical changes recently taking place in business arena is the reduction of production and distribution costs of both physical goods and information due to the advancement and the wide diffusion of information technology. The cost reduction combined with lowered priced elasticity incurred by customized products and services, will enable many firms to adopt the mass customization strategy.

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Thermo-Chemical Analysis of a Calcination Furnace to Produce Cathode Material for the Secondary Batteries (이차전지 양극활물질 제조용 소성로의 열화학적 해석)

  • Hwang, Min-Young;Kim, Yong-Gyun;Jeon, Chung-Hwan;Song, Ju-Hun;Kim, Yong-Tae;Chang, Youn-Han
    • Journal of the Korean Electrochemical Society
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    • v.12 no.2
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    • pp.155-161
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    • 2009
  • Lithium secondary batteries have been widely used in the portable electric devices as power source. Recently it is expected that the realm of its applications expands to the markets such as energy storage medium of hybrid electric vehicle(HEV), electric vehicle(EV). Cathode active material is crucial in terms of performance, durability, capacity of lithium secondary batteries. It is urgent to develope the technology for mass production of cathode material to cope with the markets' demands in the near future. In this study, a calcination furnace running in real production line is modelled in 3D, and the thermal flow and gas flow after chemical reaction in the furnace is analyzed through numerical computations. Based on the results, it is shown that large volume of $CO_2$ gas is generated from chemical reaction. High concentration of $CO_2$ gas and it's stagnation is clearly found from the reactant containers in which the reaction occur to the bottom area of the furnace. It is also studied that 15% or more $CO_2$ mol fraction could affect to proper formation of $LiCoO_2$ through TGA-DSC analysis. The solutions to evacuate carbon dioxide from the furnace are suggested through the change of furnace design and operating condition as well.

Study on Design Technology of Heat Pump Cycle for High Temperature Performance (고온 생산용 열펌프 사이클 설계)

  • Kim, Jong-Ryul;Kim, Seok-Young;Kim, Yong-Min;Lee, Kong-Hoon;Kim, Ook-Joong;Yi, Sung-Chul;Jung, Chi-Young;Kim, Jong-Ryeol
    • Journal of Energy Engineering
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    • v.19 no.4
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    • pp.228-233
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    • 2010
  • About 55% of total energy is consumed in the industrial division. The industrial heat pump application will show magnificent energy saving effect as well as higher cost efficiency because of larger energy consuming volume of each facility and longer operation hour and higher stability against seasonal temperature change. Over 90% of dryer for industrial usage has hot wind heat source and hot wind dryer is the representative type covering 68.7% while its 30 ~ 50% lower heat efficiency causes lots of energy loss by exhaust air. Re-usage of exhaust air can improve energy efficiency of dryer because 68% heat energy or 78% of hot air lose in exhaust air. Therefore, high temperature heat pump dryer can be the best alternative. Comparing to the existing dryer with 30% ~ 50% energy efficiency, newly developing high temperature heat pump dryer will enhance energy efficiency up to 60% ~ 80% efficiency. In this paper, heat pump system for high temperature was designed, constructed and tested. The results have shown that system COPh is estimated as 3.3.

Evaluation and Design of Infiltration and Filtration BMP Facility (침투 여과형 비점오염저감시설의 설계 및 평가)

  • Choi, Ji-Yeon;Maniquiz, Marla Chua;Lee, So-Young;Kang, Chang-Guk;Lee, Jung-Yong;Kang, Hee-Man;Kim, Lee-Hyung
    • Journal of Environmental Impact Assessment
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    • v.19 no.5
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    • pp.475-481
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    • 2010
  • Lots of pollutants typically originating from urban transportation are accumulating on the paved surfaces during dry periods and are washed-off directly to the river during a storm. Also, paved surfaces are contributing to increase in peak flows and volume of stormwater flows. These are the main reasons why the water quality of rivers and lakes remain polluted and still below standards. Currently, several management practices are being applied in developed countries but the design standards are still lacking. This research was conducted to develop a treatment technology that can be useful to address the problems concerning runoff quality and quantity. A lab scale infiltration device consisting of a pretreatment tank and media zone was designed and tested for various flow regimes characterizing the low, average and high intensity rainfall. Based on the experiments, the high intensity flow resulted to increase in outflow event mean concentration (EMC) of pollutants, about twice as much as the average outflow EMC. However, 78 to 88% of the total suspended solids were captured and retained in the pretreatment tank because of sedimentation. The removal of heavy metals such as zinc and lead was greatly affected by the vertical placement of woodchip layer prior to the media zone. It was observed that the high carbon content (almost 50%) in the woodchip provided opportunity for enhancing its uptake of metal by adsorption. The findings implied that the reduction of pollutants can be greatly achieved by means of proper pretreatment to allow for settling of particles with a combination of using high carbon source media like woodchip and a geotextile mat to reduce the flow before filtering into the media zone and finally discharging to the drainage system.

Assessment of Performances of Low Impact Development (LID) Facilities with Vegetation (식생이 조성된 LID 시설의 효율 평가)

  • Hong, Jung Sun;Kim, Lee-Hyung
    • Ecology and Resilient Infrastructure
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    • v.3 no.2
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    • pp.100-109
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    • 2016
  • Low impact development (LID) facilities are established for the purpose of restoring the natural hydrologic cycle as well as the removal of pollutants from stormwater runoff. Improved efficiency of LID facilities can be obtained through the optimized interaction of their major components (i.e., plant, soil, filter media, microorganisms, etc.). Therefore, this study was performed to evaluate the performances of LID facilities in terms of runoff and pollutant reduction and also to provide an optimal maintenance method. The monitoring was conducted on four LID technologies (e.g., bioretention, small wetlands, rain garden and tree box filter). The optimal SA/CA (facility surface area / catchment area) ratio for runoff reduction greater than 40% is determined to be 1 - 5%. Since runoff reduction affects the pollutant removal efficiency in LID facilities, SA/CA ratio is derived as an important factor in designing LID facilities. The LID facilities that are found to be effective in reducing stormwater runoff are in the following order: rain garden > tree box filter > bioretention> small wetland. Meanwhile, in terms of removal of particulate matter (TSS), the effectiveness of the facilities are in the following order: rain garden > tree box filter > small wetland > bioretention; rain gardens > tree box filter > bioretention > small wetland were determined for the removal of organic matter (COD, TOC), nutrients (TN, TP) and heavy metals (Cu, Pb, Cd, Zn). These results can be used as an important material for the design of LID facilities in runoff volume and pollutant reduction.

Interlaboratory Study for Cryptosporidium and Giardia Test Methods in Water (정수장 원생동물 분석방법의 국내 실험실간 교차시험 연구)

  • Chung, Hyenmi;Park, Sangjung;Kim, Daekyun;Park, Sanghee;Kim, Reeho;Lee, Sangho;Cho, Joorae;Lee, Kyeunghee;Park, Jonggeun;Lee, Mokyoung;Byun, Seungheon;Cho, Eunju;Rhim, Yeontaek
    • Journal of Korean Society on Water Environment
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    • v.22 no.2
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    • pp.321-327
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    • 2006
  • This interlaboratory study was designed to evaluate protozoan test methods in water and to predict the major causes of deviation of the methods. Each of four laboratories with previous experience of protozoa analysis in water participated, and met the initial performance criteria of EPA 1623 method provided. The protozoan analysis procedure consists of filtrations, concentration, immunomagnetic separation, dyeing (staining) and counting with observation. We tested three different filtration equipments: capsule filter for 10 L of surface water, and high volume (HV) capsule filter and membrane filter for 100 L of finished water. When the recovery of each step of the procedure was evaluated with EasySeed, the commercial stock of each 100 Cryptosporidium and Giardia, immunomagnetic separation and filtration step were the most crucial steps affecting the stability of the recovery, especially for Cryptosporidium. There was no significant difference of recovery among the filtration methods. Recovery of protozoa from source water were evaluated with spiked EasySeed as matrix tests. The recoveries of Giardia increased significantly in the matrix tests compared those in the deionized water. We also applied red stained mixture stocks of Cryptosporidium and Giardia called ColorSeed as internal standards of water sample tests. The recoveries of both EasySeed and ColorSeed in samples tested were within the range of the criteria, however, the Giardia recoveries using ColorSeed decreased significantly. Further optimization study with ColorSeed will be necessary, considering the convenience of using the internal standard without additional sample analysis. The significant factors of the recovery variation were identified as the differences of laboratories as well as water quality and type of the stock for spiking. The results of this study emphasize the importance of the quality assurance program for protozoan analysis lab in water.

A Study of the Exclusive Embedded A/D Converter Using the Microprocessor and the Noise Decrease for the Magnetic Camera (마이크로프로세서를 이용한 자기카메라 전용 임베디드형 AD 변환기 및 잡음 감소에 관한 연구)

  • Lee, Jin-Yi;Hwang, Ji-Seong;Song, Ha-Ryong
    • Journal of the Korean Society for Nondestructive Testing
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    • v.26 no.2
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    • pp.99-107
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    • 2006
  • Magnetic nondestructive testing is very useful far detecting a crack on the surface or near of the surface of the ferromagnetic materials. The distribution of the magnetic flux leakage (DMFL) on a specimen has to be obtained quantitatively to evaluate the crack. The magnetic camera is proposed to obtain the DMFL at the large lift-off. The magnetic camera consists of a magnetic source, magnetic lens, analog to digital converters (ADCs), interface, and computer. The magnetic leakage fields or the distorted magnetic fields from the object, which are concentrated on the magnetic lens, are converted to analog electrical signals tv arrayed small magnetic sensors. These analog signals are converted to digital signals by the ADCs, and are stored, imaged, and processed by the interface and computer. However the magnetic camera has limitations with respect to converting and switching speed, full range and resolution, direct memory access (DMA), temporary storage speed and volume because common ADCs were used. Improved techniques, such as those that introduce the operational amplifier (OP-Amp), amplify the signal, reduce the connection line, and use the low pass filter (LPF) to increase the signal to noise ratio are necessary. This paper proposes the exclusive embedded ADC including OP-Amp, LPF, microprocessor and DMA circuit for the magnetic camera to satisfy the conditions mentioned above.