• Journal of the Society of Cosmetic Scientists of Korea
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• v.33 no.2
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• pp.79-86
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• 2007

The aim of this study was to investigate the inhibitory effects of Forsythia suspensa fruit extracts (FSfE) ($0.1{\sim}1.0%$) and their active component on melanogenesis. FSfE dose-dependently inhibited melanin synthesis (up to $63.1{\pm}3.1%$ at the concentration of 1.0%) without cell cytotoxicity. We purifed one active compound from FSfE and identified its structure. It was identified as 4-[(3,4-Dimethoxyphenyl)methyl)]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone (arctigenin) by $^1H-NMR,\;^{13}C-NMR$, and Mass analysis. Arctigenin also inhibited melanin synthesis in a dose dependent manner (up to $52.7{\pm}3.1%$ at the concentration of $3.0{\mu}g/mL$). In order to verify the whitening activity of the cream containing 3% FSfE, we performed the clinical test with twenty five female volunteers for 8 weeks. Bioengineering analyses and visual assessment by doctors at the initial time point and 8 weeks after applications showed that cream containing FSfE have significant whiteining effect (paired t-test). From the results, we conclude that the FSfE can be used as a useful whitening agent.

• Journal of Convergence for Information Technology
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• v.10 no.2
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• pp.184-192
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• 2020

This study presents a gait analysis method (including time series analysis) using a smart insole as an objective and quantitative evaluating method after lumbar scoliosis surgery. The participant is a degenerative lumbar scoliosis patient. She took 3-min-gait-test four times(before and 8, 16, and 204-days after surgery) and 6-min-gait-test once(204-days after surgery) with smart-insoles in her shoes. Each insole has 8-pressure sensors, an accelerometer, and a gyroscope. The measured values were used to compare the characteristics of gait before and after surgery. The analysis showed that all of the patient's gait parameters improved after surgery. And after 6 months, the gait was more stable. However, after long walk, the swing duration of one leg was slightly shorter than that of the other again. It was a preclinical problem that could not be found in the visual examination by the practitioner. With this analysis method we could evaluate the improvement of patient quantitatively and objectively. And we could find a preclinical problem. This analysis method will lead to the studies that define and distinguish gait patterns of certain diseases, helping to determine appropriate treatments.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.9 no.2
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• pp.323-334
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• 2002

Purpose: This study was designed to verify preemptive effects of intravenous patient-controlled analgesia (IV-PCA) infusion on postoperative pain in women having a total abdominal hysterectomy. Method: The research design was a nonequivalent control group post test only design. The participants in this study were 50 women who were scheduled for a total abdominal hysterectomy at a University affiliated Hospital in Suwon, Korea. The subjects were divided into two groups. For the experimental group, IV-PCA infusion was started before the skin incision and for the control group. IV-PCA infusion was started after the skin was closed. Each group was evaluated in terms of pain score by the visual analogue scale (VAS) and the number of times they pushed the button for IV-PCA at postoperative hours 1, 2, 3, 6, 12, and 24. The data were collected from July 1 to December 10, 2001. Collected data was analyzed by SPSS/PC + program. Result: 1. There was no difference between the two groups, over six points for the number of times the control button for IV-PCA was used. Group differences and interaction effect were not significant. 2. There was no significant difference in pain scores between the two groups, over seven time points. A significant interaction effect was observed between groups and measurement Points in time. 3. There was a significant difference in the requirements for additional analgesia between the two groups, 32% of the control group received additional analgesia. Conclusion: Preemptive analgesics administration may have a better effect in relieving postoperative pain than the usual analgesic treatment which is started after surgery.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.5 no.2
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• pp.113-125
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• 2010

Objectives: We have evaluated the effects of conservative treatment on one patient who was diagnosed to thoraco-lumbar junction and lumbo-sacral junction transitional zone syndrome. so, we investigate thoraco-lumbar junction and Jumbo-sacral junction tranzitional zone syndrome that was suggested by Maigne R. Methods : One patient was diagnosed as T12-L1 herinated intervetebral disc through MRI. We diagnosed the patient to transitional zone syndrome by symptoms and physical examination and used Acupuncture therapy, Cox technique to the patient. We measured Visual Analog Scale(VAS) before and after treatment. Results: After treating Acupuncture therapy, Cox technique in the case, We find out that the patient was improved. VAS score changed from 7 to 2 and physical examinations are improved. Conclusions: We improved the patient who had thoraco-lumbar junction and lumbo-sacral junction transitional zone syndrome by Cox technique and Acupuncture therapy, and we found that thoraco-lumbar junction related lumbo-sacral junction.

• Journal of Korean Public Health Nursing
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• v.18 no.1
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• pp.80-89
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• 2004

This study focused on individual health education for people with hypertension who were being seen in public health centers. The program was an adjusted intervention program that considered the characteristics of each individual and reflected the individual's will to change. Each individual had a different lifestyle with different characteristics and habits so the study considered these individual's characteristics. A comparison was done of knowledge related to hypertension, self-efficacy, and self-care in these individuals. In order to determine the effectiveness of education given by the nurses the variables were measured before and after the individual health education program. The participants in this study were 85 people with hypertension who were seen at a public health center in G city. They were assigned to an experimental group (43) and a control group (42). A tool developed by Park Young-Im (1994) was used to measure knowledge related to hypertension and self-efficacy. A tool developed by Lee Young-Whee (1994) was used for self-care. Data collection was done for 10 weeks from March 24 to May 31, 2003 using interviews with questionnaires. The following is a summary of the results of the study. Hypothesis 1, 'the experimental group which had the individual health education will have higher knowledge scores on hypertension than the control group that did not have the individual health education' was supported (t=4.17, P=0.00). Hypothesis 2, 'the experimental group which had the individual health education will have higher self-efficacy scores than the control group that did not have the individual health education' was supported (t=4.06, P=0.00). Hypothesis 3, 'the experimental group which had the individual health education will have better self-care ability than the control group that did not have the individual health education' was supported (t=4.94, P=0.00). Based on the results of this study, the public health centers should develop an educational program that uses a variety of visual aids and assess the effects of the education on patients with different chronic diseases. After the development of an inclusive education program which will standardize health education effectively and provide a variety of teaching methods, study is needed to measure changes in lifestyle after education and to determine how much knowledge related to hypertension, self-efficacy, and self-care increase

• Journal of Korean Medicine Rehabilitation
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• v.30 no.4
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• pp.165-178
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• 2020

Objectives This survey study is designed to check the awareness and satisfaction of Korean herbal medicine in patients suffering from acute traffic accidents. Methods From May 1 to 20, 2020, patients who visited the hospital within 7 days after the accident and received prescription of Korean herbal medicine for the first-time symptoms were selected. Survey was conducted 10 days after the first visit to confirm the perception of Korean herbal medicine and expected to be used as a prior study to improve the quality of Korean medicine led by Korean herbal medicine. Results Most patients answered that they were aware of the prescribed Korean herbal medicine's dosage and treatment effects. 65% of the patients said they would like to receive other forms of prescription if possible. Most patients answered that portability is convenient and tastes better than normal. 48% of the respondents said that it was the first to time to take Korean herbal medicine, and 68% said that they were willing to take the Korean herbal medicine later. At the time of the first visit, the health condition assessed using EuroQol visual analogue scale (EQ-VAS) was 46.84, but 10 days after the treatment began, it increased significantly to 61.93. Conclusions The improvement of symptoms and high satisfaction with Korean medicine medical services contributed to the patient's willingness to visit the Korean medicine hospital again and to respond that they were willing to take further medication. EQ-VAS elevation suggests that overall patients' subjective health conditions have improved since treatment.

• Journal of Periodontal and Implant Science
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• v.38 no.1
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• pp.1-6
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• 2008

Purpose: The purpose of this study was to evaluate the effects of hydroxyapatite containing toothpaste for patients who received periodontal therapy and felt hypersensiptivity. Material and Methods: After application of toothpaste, patients were evaluated for VAS(Visual Analog scale) scores to a cold stimulate on baseline, 1 week, and 4 weeks. VAS scores were analyzed by statistical methods. Results: The results of this study were as follows. 1. VAS scores in control group on baseline, 1 week, 4 weeks were $5.39{\pm}2.05$, $4.75{\pm}2.00$, $4.21{\pm}1.75$. 2. VAS scores in experimental group on baseline, 1 week, 4 weeks were $5.61{\pm}2.37$, $4.81{\pm}2.46$, $4.08{\pm}2.54$. 3. Decrease of VAS scores on hypersensitivity after 1week was $0.64{\pm}0.49$(p<.0001) in control group, $0.80{\pm}1.65$ (p<.0001) in experimental group. 4. Decrease of VAS scores on hypersensitivity after 4weeks was $1.18{\pm}1.60$(p<.0001) in control group, $1.53{\pm}1.88$ (p<.0001) in experimental group. 5. When compared, decrease of VAS scores after 1 week between 2 groups were not statistically different(p=0.2622). 6. When compared, decrease of VAS scores after 4 weeks between 2 groups were not statistically different(p=0.1219). Conclusion: It was confirmed that hydroxyapatite containing toothpaste have the similar effect with pre-existing proven dentifrice for relieving teeth hypersensitivity.

• Journal of The Korean Association For Science Education
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• v.31 no.6
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• pp.931-941
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• 2011

This study aimed to examine the effects of argument-based chemistry laboratory investigations using the Science Writing Heuristic (SWH) approach on students' use and embedding of multimodal representations in summary writing. Participants of this study were thirty-nine freshman students majoring in science education at a National University in Korea. Argument-based chemistry laboratory investigations using the SWH approach were implemented for twenty-three students enrolled in one cohort, and the traditional chemistry laboratory teaching was implemented for 16 students enrolled in the other cohort. Summary writing samples were collected from students before and after the implementation. Summary writing samples produced by students were examined using an analysis framework for examining the use and embeddedness of multimodal representations. Summary writing was categorized into one of verbal mode, symbolic mode, and visual mode. With regard to the embedding of multi-modal representations, summary writing samples were analyzed in terms of 'constructing understanding,' 'integrating multiple modes,' 'providing valid claims and evidence,' and 'representing multiple modes.' Data analysis shows that the students of the SWH group were better at utilizing and embedding multimodal representations in summary writing as they provided evidence supporting their claims. This study provides important implications on pre-service science teacher education.

• Sleep Medicine and Psychophysiology
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• v.6 no.1
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• pp.61-67
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• 1999

Objectives: The aim of this study was to examine the impact of shift work on psychological, physical and social adjustment in nurses. Methods: Two hundred ninety-nine female nurses(179 shift worker, 120 non-shift worker) filled out a questionnaire, which consisted of fifty-six items including demographic characteristics. Subjective ratings of psychological, physical, social and sleeprelated distresses were assessed with a visual analogue scale(100mm). Results: Shift work exerted significantly negative impacts on all psychological, physical, social and sleep-related variables of the shift work nurses. The subjective perception about psychological and physical health of shift work nurses was significantly negative as compared to that of non-shift work nurses. Shift work nurses complained of more shift work related social dysfunction and limited social activity. Shift work nurses were also suffering from significant sleep difficulties as compared to non-shift work nurses. Conclusions: This study suggests that shift work can exert a negative impact on psychological and physical health of nurses as it can cause disturbances of the normal circadian rhythms of the psychophysiological functions, beginning with the sleep-wake cycle. Shift work can also cause difficulties in maintaining the usual relationships both at family and social levels. These results may suggest that we need appropriate coping strategies to overcome adverse effects of shift work.

• Journal of Service Research and Studies
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• v.5 no.2
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• pp.133-147
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• 2015

The purpose of this study was to suggest and prove that service design is not in the dimension of a simply new design methodology, but in the design paradigm change from conventional tangible and visual view of design to the intangible service of design. Based on a variety of literature research, this study defined service design, found its characteristics, and proved its differences from conventional design approaches and thoughts. To do that, this study looked into service design theories, processes, and methodologies, defined quality factor and availability of service design, and user satisfaction, and setup hypotheses to prove them. This study conducted a questionnaire survey with service design firms, service designers, and their customers. The questionnaire data were applied to structural equation to analyze the hypotheses. According to the analysis, reliability, tangibility, assurance, and empathy of the quality factors of service design were accepted, but responsiveness of the factors was rejected. It was found that quality factors positively influenced availability and ended up positively affecting user satisfaction. The quantitative research results will made some suggestions to service design firms and designers in the paradigm change to service-centric design, and will show the importance of understanding the essence of service in terms of design methodology.