• Progress in Medical Physics
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• v.18 no.1
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• pp.42-47
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• 2007

Purpose: To evaluate the tracing of optic nerve tract using manganese enhanced magnetic resonance Imaging. Materials and Methods: After injecting $30{\mu}l$ of $MnCl_2(1mol)$ (1 mol) Into the retina of female New Zealand white rabbit, the contrast enhancements at major anatomical structures of optic nerve tract were evaluated by high resolution T1-weighted Images 12 hours, 24 hours, and 48 hours after $MnCl_2(1mol)$ Injection using 3D FSPGR (Fast Speiled Gradient Recalled echo) pulse sequence at 1.5T clinical MR scanner with high performance gradient system. Also, for quantitative evaluation, the signal-to-noise ratios of circular ROI on anatomical locations were measured. Results: The major structures on the optic nerve tract were enhanced after injecting $MnCl_2(1mol)$. The structures, which showed enhancement, were right optic nerve, optic chiasm, left optic tract, left lateral geniculate nucleus, left superior colliculus. The structures on the contralateral optic pathway to the right retina were enhanced whereas the structures on the ipsilateral pathway did not show enhancement. Conclusion: The Mn transport through axonal pathway of optic nerve sys)em was non- invasively observed after injecting injecting $MnCl_2$ at the retina, which is the end terminal of optic nerve system. This Mn transport seems to occur by voltage gated calcium $(Ca^{2+})$ channel and In case of direct Injection Into the retina, the fast transpori pathway of voltage gated calcium channel seems to be responsible for Mn transport.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.43 no.1 s.307
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• pp.45-54
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• 2006

This paper proposed color matching technique, including display characterization, chromatic adaptation model, and gamut mapping and extension, to generate consistent colors for the same input signal in each display device. It is necessary to characterize the relationship between input and output colors for display device, to apply chromatic adaptation model considering the difference of reference white, and to compensate for the gamut which display devices can represent for reproducing consistent colors on DTV display devices. In this paper, 9 channel-independent GOG model, which is improved from conventional 3 channel GOG(gain, offset gamma) model, is used to consider channel interaction and enhance the modeling accuracy. Then, the input images have to be adjusted to compensate for the limited gamut of each display device. We proposed the gamut mapping and extension method, preserving lightness and hue of an original image and enhancing the saturation of an original image in xy chromaticity diagram. Since the hmm visual system is more sensitive to lightness and hue, these values are maintained as the values of input signal, and the enhancement of saturation is changed to the ratio of input and output gamut. Also the xy chromaticity diagram is effective to reduce the complexity of establishing gamut boundary and the process of reproducing moving-pictures in DTV display devices. As a result, reproducing accurate colors can be implemented when the proposed method is applied to LCD and PDP display devices

• Journal of the Korean Society of Radiology
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• v.14 no.5
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• pp.635-642
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• 2020

The purpose of this study was to analysis the effects of shielding area of field configuration with changing of sensitivity and density on tube current (milliampere-seconds, mAs) and image quality in automatic exposure control (AEC) system. The equipment used a digital radiography device (Digital Diagnost, Philips, Netherlands), which has a integral type with an X-ray tube and an indirect digital detector. The AEC system conditions were consisted of 9 setting environments, that mode changing of the sensitivity (S200, S400, S800) and the density (+2.5, 0, -2.5). The tube current evaluated automatically exposed mAs under 81 combination conditions crossed by AEC conditions in fixed at 40 kVp. The image quality evaluated the radiographic images that selected valid images by visual assessment the radiographic images of the self-produced conical pyramid phantom and then measured their signal to noise ratio (SNR). As a result, the maximum tube current was 60.0 mAs that automatically exposed conditions were the 100% of shielding area and the sensitivity of S200 and the density of +2.5. The minimum tube current was 0.9 mAs with non-shielding area and the sensitivity of S800 and the density of -2.5. When the shielded area 0% with the sensitivity of S200 and the density of +2.5, the maximum SNR was the highest as 25.2. But when the shielded area 25% with the sensitivity of S800 and the density of -2.5, the minimum SNR was the lowest as 4.7.

• Korean Journal of Optics and Photonics
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• v.15 no.5
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• pp.435-442
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• 2004

We obtained precise linear transverse displacements from the results of signal processing on moire fringes measured by the superposition of a fixed self-imaging elongated circular(EC) grating and a moved EC grating. The linear displacement less than one pitch of the moving EC grating was calculated from the position of a bright moire fringe generated on the linear grating part of the EC gratings. The moire signals were high-frequency-filtered, smoothed, curve-fitted, and first-differentiated moire signals in sequence. Also the linear displacement created by movement by the unit of integer times of a pitch was readily measured by the count of the even number of zero-crossing points corresponding to bright moire fringes obtained by the above same processing without curve fitting. Then we can measure linear transverse displacements with the accuracy of better than 3 %, which are more accurate values than those by the traditional visual method within the displacement of 80 ${\mu}{\textrm}{m}$.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.39 no.5
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• pp.11-20
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• 2002

Based on regularization principles, we propose a new dequantization scheme on DCT-based transform coding for reducing of blocking artifacts and minimizing the quantization error. The conventional image dequantization is simply to multiply the received quantized DCT coefficients by the quantization matrix. Therefore, for each DCT coefficients, we premise that the quantization noise is as large as half quantizer step size (in DCT domain). Our approach is based on basic constraint that quantization error is bounded to ${\pm}$(quantizer spacing/2) and at least there are not high frequency components corresponding to discontinuities across block boundaries of the images. Through regularization, our proposed dequantization scheme, sharply reduces blocking artifacts in decoded images. Our proposed algorithm guarantees that the dequantization process will map the quantized DCT coefficients will be evaluated against the standard JPEG, MPEG-1 and H.263 (with Annex J deblocking filter) decoding process. The experimental results will show visual improvements as well as numerical improvements in terms of the peak-signal-to-noise ratio (PSNR) and the blockiness measure (BM) to be defined.

• The KIPS Transactions:PartC
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• v.18C no.4
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• pp.265-278
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• 2011

The objective of this paper is to analyze and characterize end-to-end packet statistics after modeling and simulation of WiFi (IEEE 802.11g) and WiMAX (IEEE 802.16e) of a virtual wireless network using OPNET Modeler Wireless Suite. Wireless internal and external network simulators such as Remcom's Wireless InSite Real Time (RT) module, WinProp: W-LAN/Fixed WiMAX/Mobile WiMAX, and SMI system, are designed to consider data transfer rate based on wireless propagation signal strength. However, we approached our research in a different perspective without support for characteristic of these wireless network simulators. That is, we will discuss the purpose of a visual analysis for these packets, how to receive each point packets (e.g., wireless user, base station or access point, and http server) through end-to-end virtual network modeling based on integrated wired and wireless network without wireless propagation signal strength. Measuring packet statistics is important in QoS metric analysis among wireless network performance metrics. Clear packet statistics is an especially essential metric in guaranteeing QoS for WiMAX users. We have found some interesting results through modeling and simulation for virtual wireless network using OPNET Modeler Wireless Suite. We are also able to analyze multi-view efficiency through experiment/observation result.

• Korean Journal of Animal Reproduction
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• v.9 no.2
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• pp.133-139
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• 1985

An immunoassay may be defined as an analytical procedure involving the competitive reaction between a limiting concentration of specific antibody and two populations of antigen, one of which is labelled or immobillized. The advent of immunoassay has revolutionised our knowledge of reproductive physiology and the practice of veterinary and clinical medicine. Radioimmunoassay (RIA) was the first of these methods to be developed, which meausred the analyte with good sensitivity, accuracy and precision (1,2). The essential components of RIA are:-(i) a limited concentration of antibodies, (ii) a reference preparation, and (iii) an antigen labelled with a radioisotope (usually tritium or iodine-125). Most procedures invelove isolating the antibody-bound fraction and measuring the amount of labelled antigen. Good facilities are available for scintilltion counting, data reduction nd statistical analysis. RIA is undergoing refinement through:-(i) the introduction of new techniques to separate the antibody-bound and free fractions which minimize the misclassification of labelled antigen into these compartments, and the amount of non-specfic binding. (3), (ii) the development of non-extration for the measurement of haptens (4), (iii) the determination of a, pp.rent free (i.e. non-protein bound) analytes (5), and (iv) the use of monoclonal antibodies(6). In 1968, Miles and Hales introduced in important new type of immunoassay which they termed immunora-diometric assay (IRMA) based on t도 use of isotopically labelled specific antibodies(7) in a move from limited to excess reagent systems. The concept of two-site IRMAs (with a capture antibody on a solid-phase, and a second labelled antibody to a different antigenic determinant of the analyte) has enabled the development of more sensitive and less-time consuming methods for the measurement of protein hormones ovar wide concentration of analyte (8). The increasing use of isotopic methos for diverse a, pp.ications has exposed several problems. For example, the radioactive half-life and radiolysis of the labelled reagent limits assay sensitivity and imposes a time limit on the usefulness of a kit. In addition, the potential health hazards associated with the use and disposal of radioactive cmpounds and the solvents and photofluors necessary for liquid scientillation counting are incompatable with the development of extra-laboratory tests. To date, the most practical alternative labels to radioisotopes, for the measurement of analytes in a concentration > 1 ng/ml, are erythrocytes, polystyrene particiles, gold sols, dyes and enzymes or cofactors with a visual or colorimetric end-point(9). Increased sensitivity to<1 pg/ml may be obtained with fluorescent and chemiluminescent labels, or enzymes with a fluorometric, chemiluminometric or bioluminometric end-point. The sensitivity of any immunoassay or immunometric assay depends on the affinity of the antibody-antigen reaction, the specific activity of the label, the precision with which the reagents are manipulated and the nonspecific background signal (10). The sensitivity of a limited reagent system for the measurement of haptens or proteins is mainly dependent upon the affinity of the antibodies and the smalleest amount of reagent that may be manipulated. Consequently, it is difficult in practice to improve on the sensitivity obtained with iodine-125 as the label. Conversely, with excess reagent systems for the measurement of proteins it is theoretically possible to increase assay sensitivity at least 1000 fold with alternative luminescent labels. To date, a 10-fold improvement has been achieved, and attempts are being made to reduce the influence of other variables on the specific signal from the immunoreaction.

• Korean Journal of Radiology
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• v.22 no.6
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• pp.922-930
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• 2021

Objective: It is uncertain why a b-value range of 1500-2000 s/mm² is optimal. This study was aimed at qualitatively and quantitatively analyzing the optimal b-value range of synthetic diffusion-weighted imaging (sDWI) for evaluating prostatic index lesions. Materials and Methods: This retrospective study included 92 patients who underwent DWI and targeted biopsy for magnetic resonance imaging (MRI)-suggested index lesions. We generated sDWI at a b-value range of 1000-3000 s/mm² using dedicated software and true DWI data at b-values of 0, 100, and 1000 s/mm². We hypothesized that lesion conspicuity would be best when the background (i.e., MRI-suggested benign prostatic [bP] and periprostatic [pP] regions) signal intensity (SI) is suppressed and becomes homogeneous. To prove this hypothesis, we performed both qualitative and quantitative analyses. For qualitative analysis, two independent readers analyzed the b-value showing the best visual conspicuity of an MRI-suggested index lesion. For quantitative analysis, the readers assessed the b-value showing the same bP and pP region SI. The 95% confidence interval (CI) or interquartile range of qualitatively and quantitatively selected optimal b-values was assessed, and the mean difference between qualitatively and quantitatively selected b-values was investigated. Results: The 95% CIs of optimal b-values from qualitative and quantitative analyses were 1761-1805 s/mm² and 1640-1771 s/mm² (median, 1790 s/mm² vs. 1705 s/mm²; p = 0.003) for reader 1, and 1835-1895 s/mm² and 1705-1841 s/mm² (median, 1872 s/mm² vs. 1763 s/mm²; p = 0.022) for reader 2, respectively. Interquartile ranges of qualitatively and quantitatively selected optimal b-values were 1735-1873 s/mm² and 1573-1867 s/mm² for reader 1, and 1775-1945 s/mm² and 1591-1955 s/mm² for reader 2, respectively. Bland-Altman plots consistently demonstrated a mean difference of less than 100 s/mm² between qualitatively and quantitatively selected optimal b-values. Conclusion: b-value range showing a homogeneous background signal may be optimal for evaluating prostatic index lesions on sDWI. Our qualitative and quantitative data consistently recommend b-values of 1500-2000 s/mm².

• Journal of the Institute of Convergence Signal Processing
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• v.24 no.4
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• pp.205-212
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• 2023

Among cardiac diseases, arrhythmias can lead to serious complications such as stroke, heart attack, and heart failure if left untreated, so continuous and accurate ECG monitoring is crucial for clinical care. However, the accurate interpretation of electrocardiogram (ECG) data is entirely dependent on medical doctors, which requires additional time and cost. Therefore, this paper proposes an arrhythmia recognition module for the purpose of developing a medical platform through the analysis of abnormal pulse waveforms based on Lifelogs. The proposed method is to convert ECG data into image format instead of time series data, apply visual pattern recognition technology, and then detect arrhythmia using CNN model. In order to validate the arrhythmia classification of the CNN model by image type conversion of ECG data proposed in this paper, the MIT-BIH arrhythmia dataset was used, and the result showed an accuracy of 97%.

• KIISE Transactions on Computing Practices
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• v.24 no.1
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• pp.1-9
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• 2018

Low-power long-range networks (LoRa) has a comprehensive coverage of up to 30 km, so that long-range positioning is possible. However, the position error in the current LoRa environment is over 500 m. This makes it difficult to use practical location services in the LoRa environment. In this paper, we propose a method to improve the position accuracy by correcting an inaccurate visual error when sending a signal from a mobile node to a gateway through the reference node of each zone in the LoRa environment. Experiments were carried out using MATLAB, and a radio propagation algorithm, the Hata model, was used to cancel out the stationary noise and to evaluate the environmental noise. Experimental results showed that the error range decreased as the number of reference nodes increased and a mobile node approach the reference node.