• Title/Summary/Keyword: Vision disorders

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Comparison of the Static Balance Ability according to the Subjective Visual Vertical in Healthy Adults

  • Kwon, Jung Won;Yeo, Sang Seok
    • The Journal of Korean Physical Therapy
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    • 제32권3호
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    • pp.152-156
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    • 2020
  • Purpose: The subjective visual vertical (SVV) test is used to evaluate the otolith function in the inner ear. This study compared the different balance ability according to the results of the SVV in healthy adults. Methods: This study recruited 30 normal healthy subjects who did not have neurological and musculoskeletal disorders. The subjects were divided into experimental and control groups based on the results of SVV: experimental group, >2°; control group, <2°. The static balance ability was evaluated using the Fourier Index, which could evaluate the balance capacity objectively and quantitatively. Results: The mean angle of the SVV in the experimental and control groups was 4.44° and 0.59°, respectively. In the result of the Fourier series, the F1 frequency band in the experimental group showed a significantly higher value under one condition compared to the control group (p<0.05). In the F2-4 and F5-6 frequency bands, the experimental group showed a significant increase in the Fourier series value under the four conditions compared to the control group (p<0.05). In the F7-8 frequency band, significantly higher values of the Fourier series were observed in the experimental group under the three different conditions (p<0.05). Conclusion: These results showed increased trunk sway while maintaining static balance in the experimental group who showed a larger SVV angle compared to the control group. The SVV can be applied to evaluate the vestibular system and balance ability in normal adults.

설치류에서 Ginsenoside Rgl의 항스트레스 활성 (Anti-stress Activities of Ginsenoside Rgl in Rodents)

  • 최종현;허율;정재훈
    • 약학회지
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    • 제51권3호
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    • pp.219-227
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    • 2007
  • Ginsenoside Rgl (Rgl), the pharmacologically active constituent of ginseng (Panax ginseng C.A. Meyer), has a variety of biological activities. The present study was undertaken to evaluate a possibility of Rgl whether it can be used in treatment or prevention of stress disorders. Animals were stressed by immobilization for 2 hours or electroshocks for 20 minutes. The normal group was not exposed to any stress. Rgl was subcutaneously injected as dosages of 5 and 10 mg/kg and red ginseng (RG) was orally administered 200 mg/kg as the positive control. Animals were given supplements for 5 days without stress, and then were given supplements for 5 days with stress. We recorded stress-related behavioral changes of experimental animals using the Etho-vision system. Weight of adrenal gland and levels of corticosterone in plasma were measured and stress related behaviors (smelling, grooming, face washing, rearing) were observed. Rgl didn't make significant behavioral changes in total open field and elevated plus maze test. Rgl did not influence on behavioral changes induced by electroshock stress. Whereas, 10 mg/kg of Rgl alleviated the increment of the freezing and face washing time and the decrement of the smelling and rearing time induced by restraint stress. The administration of Rgl 10 mg/kg has significantly increased the endurance time on rotating rod and swimming pool tests compared to the control group. These results indicate that Rgl can alleviate the damage induced by physical stress. This result suggests that Rgl may bea new candidate for treating stress related disorder.

ADHD 아동의 유형별 시각 기능의 문제 발생률에 대한 융복합적 접근 (Convergence Approach to the Incidence of Visual Function Problems by the Type of ADHD in Children)

  • 조형철;노효련
    • 한국융합학회논문지
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    • 제12권2호
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    • pp.113-120
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    • 2021
  • 본 연구는 시각적인 장애를 호소하는 ADHD로 진단받은 아동의 유형별 시각 기능의 특징을 확인하고자 하였다. 연구 대상자는 ADHD로 진단받은 아동 49명으로 시각기능이 정상범위에서 벗어난 경우이다. Korean-ADHD Rating Scale을 이용하여 ADHD 유형을 알아보았고 시각기능 검사를 통해 시각 기능의 문제를 알아보았다. 시각의 문제를 가지고 있는 ADHD 아동들은 부주의 유형(69.4%)이 가장 많았으며 시력은 좋지만 시각 기능 문제가 드러난 경우도 50% 정도 되었다. 주의력결핍 유형에서 근시 관련 시각장애, 과잉활동형 유형에서 난시 관련된 시각장애가 높게 나타났다. 버전스 기능 장애에서는 폭주부족이 가장 많았으며 유형별 차이는 나타나지 않았다. ADHD 아동의 유형별 시각장애의 특성은 차이가 나타나므로 시각 기능 장애의 검사와 선별을 통해 아동의 문제행동에 접근하는 것이 필요하다.

뇌졸중 후 양안의 동측 상방 수평반맹을 호소하는 환자 한의 치험 1례 (A case study of bilateral superior altitudinal hemianopia in a stroke patient treated with Korean Medicine)

  • 최정우;김서영;김하리;신희연;양승보;조승연;박성욱;고창남;박정미
    • 대한중풍순환신경학회지
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    • 제20권1호
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    • pp.43-52
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    • 2019
  • ■ Objectives The purpose is to report the case of Korean medicine in the treatment of bilateral superior altitudinal hemianopia after a stroke. ■ Methods The patient was treated with acupuncture, electroacupuncture, bee venom, and herbal medicine. The visual field defect was assessed using humphrey visual field analyzer and confrontation visual field test. ■ Results After treatment, humphrey visual field analyzer and confrontation visual field test showed improvement in field of vision ■ Conclusion This study suggested that Korean medical treatment could be an effective option for treating visual field defect after stroke.

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Association between Visual Impairment and Nutritional Risk among Older Adults with Diabetes: A Population-Based Cross-Sectional Study

  • Yang, Eunjin;Lee, Kyung Hee
    • 대한간호학회지
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    • 제53권2호
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    • pp.167-176
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    • 2023
  • Purpose: Despite the high prevalence of visual impairment caused by diabetic retinopathy and nutritional problems among older adults with diabetes, evidence regarding factors related to nutritional risk in this population is limited. Therefore, this study aimed to identify the correlates of nutritional risk among older adults with diabetes, focusing on visual impairment. Methods: This study was a secondary data analysis of the 2020 National Survey of Older Koreans aged 65 years and above. The sample comprised 2,376 older adults with diabetes, and complex sample ANOVA and Rao-Scott chi-square tests were used to compare the groups according to visual impairment. Complex-sample logistic regression analyses were conducted to verify the association between visual impairment and nutritional risk. Results: Older adults with diabetes, who also have severe visual impairment, are more likely to have nutritional risk status than those without impairment after controlling for covariates (odds ratio [OR] = 2.44, 95% confidence interval [CI] 1.16~5.13). Among the covariates, depression (OR = 3.58, 95% CI 2.60~4.94), dependent activities of daily living status (OR = 2.79, 95% CI 1.60~4.86), and experience of hospitalization during the past year (OR = 2.51, 95% CI 1.57~4.03) were strongly associated with nutritional risk. Conclusion: Severe visual impairment increases the nutritional risk among older adults with diabetes. Therefore, it is essential to prevent visual impairment due to exacerbation of diabetes through appropriate management. Additionally, tailored nutritional interventions for visually impaired older adults with diabetes that consider visual characteristics are required.

Object Detection Based on Deep Learning Model for Two Stage Tracking with Pest Behavior Patterns in Soybean (Glycine max (L.) Merr.)

  • Yu-Hyeon Park;Junyong Song;Sang-Gyu Kim ;Tae-Hwan Jun
    • 한국작물학회:학술대회논문집
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    • 한국작물학회 2022년도 추계학술대회
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    • pp.89-89
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    • 2022
  • Soybean (Glycine max (L.) Merr.) is a representative food resource. To preserve the integrity of soybean, it is necessary to protect soybean yield and seed quality from threats of various pests and diseases. Riptortus pedestris is a well-known insect pest that causes the greatest loss of soybean yield in South Korea. This pest not only directly reduces yields but also causes disorders and diseases in plant growth. Unfortunately, no resistant soybean resources have been reported. Therefore, it is necessary to identify the distribution and movement of Riptortus pedestris at an early stage to reduce the damage caused by insect pests. Conventionally, the human eye has performed the diagnosis of agronomic traits related to pest outbreaks. However, due to human vision's subjectivity and impermanence, it is time-consuming, requires the assistance of specialists, and is labor-intensive. Therefore, the responses and behavior patterns of Riptortus pedestris to the scent of mixture R were visualized with a 3D model through the perspective of artificial intelligence. The movement patterns of Riptortus pedestris was analyzed by using time-series image data. In addition, classification was performed through visual analysis based on a deep learning model. In the object tracking, implemented using the YOLO series model, the path of the movement of pests shows a negative reaction to a mixture Rina video scene. As a result of 3D modeling using the x, y, and z-axis of the tracked objects, 80% of the subjects showed behavioral patterns consistent with the treatment of mixture R. In addition, these studies are being conducted in the soybean field and it will be possible to preserve the yield of soybeans through the application of a pest control platform to the early stage of soybeans.

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인간 망막 색소상피 세포에서 산화적 스트레스에 대한 천연 및 합성 화합물들의 세포 보호 효과 비교 (Comparison of the Cytoprotective Effects of Several Natural and Synthetic Compounds against Oxidative Stress in Human Retinal Pigment Epithelial Cells)

  • 김다혜;김정환;박세광;정지원;김미영;남수완;이혜숙;최영현
    • 생명과학회지
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    • 제31권2호
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    • pp.126-136
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    • 2021
  • 산화적 스트레스에 의한 망막 색소상피 세포의 손상 및 퇴화는 시력 소실을 포함한 다양한 망막질환의 원인으로 알려져 있다. 본 연구에서는 천연물 유래 14종 단일 성분과 합성 화합물 2종을 대상으로 망막질환 개선 가능성을 평가하기 위해, 사람 유래 망막 색소상피 세포를 대상으로 산화적 스트레스에 의한 세포 손상에 대한 보호 효능을 평가하였다. 그 결과, 16종의 후보물질 중 H2O2에 의해 유발된 세포독성을 개선시키는 효능을 보인 5종(auranofin, FK-509, hemistepsin A, honokiol 및 spermidine)을 선별하였다. 이를 기반으로 H2O2에 의한 미토콘드리아 기능 손상 및 활성 저하 억제능을 평가하였으며, auranofin을 제외한 4종에서 유의한 세포 보호 효능이 관찰되었다. 더불어 H2O2에 의해 유도된 DNA 손상에 미치는 영향을 조사한 결과, FK-506, honokiol과 spermidine이 DNA 손상을 개선시켰음을 확인하였다. 그러나 5종의 후보물질이 활성 산소종의 생성에는 뚜렷한 억제 효능을 나타내지 않았으며, 이는 5종의 후보 물질이 ROS-비의존적 기전을 통해 세포 보호효과를 나타낼 것으로 사료된다. 이상의 결과를 바탕으로, 조사 대상 후보물질 중에서 spermidine이 산화적 스트레스로부터 망막 색소상피 세포의 보호 효능이 가장 우수한 천연물 유래 단일 물질임을 규명하였으며, 동시에 합성물질로는 FK-506이 망막 세포 보호 효능이 우수한 것으로 나타났다. 비록 작용 기전에 대한 추가 연구가 필요하겠지만, 본 연구 결과는 spermidine과 FK-506이 산화적 스트레스에 의한 망막질환의 위험을 억제할 가능성이 있음을 시사한다.

습성 연령관련황반변성 환자에서 안구 방수 내 비타민 D 분석 (Analysis of 25-Hydroxy Vitamin D in the Aqueous Humor of Age-related Macular Degeneration Patients)

  • 송원석;윤원태;김용규;박성표
    • 대한안과학회지
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    • 제59권11호
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    • pp.1024-1029
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    • 2018
  • 목적: 습성 연령관련황반변성 환자의 방수 내 비타민 D 농도를 측정하여, 체내 비타민 D 농도가 질병의 임상 양상과 어떠한 관련성을 보이는지 알아보고자 한다. 대상과 방법: 50세 이상의 습성 연령관련황반변성 환자 34명 52안과, 망막 질환이 없는 백내장수술 환자 17명 23안에서 안구 방수를 채취하여 비타민 D 농도를 측정하고 비교하였다. 환자군을 안구 방수 내 비타민 D 수치의 중간값을 기준으로 수치가 높은 군과 낮은군으로 나누어 황반변성과 관련된 여러 임상 양상과의 관련성을 살펴보았다. 결과: 황반변성군에서 대조군에 비해 안구 방수 내 비타민 D 농도가 유의하게 낮았다(황반변성군 $10.03{\pm}10.1ng/mL$ vs. 대조군 $40.8{\pm}16.4ng/mL$, p<0.001). 환자군 내에서 비타민 D 수치가 높은 군은 낮은 군에 비해 섬유혈관성 망막색소상피박리 유형의 비율이 높았다(높은 군 65% vs. 낮은 군 27%, p=0.003). 다중 선형 회귀 분석 결과 안구 방수 내 비타민 D 수치와 6개월 이내 총 주사 횟수와 유의한 관련성을 보였다(standardize coefficient ${\beta}=-0.336$). 결론: 습성 연령관련황반변성 환자는 대조군에 비해 안구 방수 내 비타민 D 수치가 유의하게 낮았다. 하지만 환자군 내에서는 비타민 D 수치가 낮을 시 더 많은 유리체강 내 주사치료 횟수와 관련되는 한편, 수치가 높은 경우 섬유혈관성 망막색소상피박리 및 더 낮은 시력과 관련을 보이는 등 관련성은 일정하지 않았다. 눈에서의 국소적인 비타민 D 수치와 질환과의 관련성에 대한 추가 연구가 필요하겠다.