• International Journal of Naval Architecture and Ocean Engineering
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• 제13권1호
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• pp.147-162
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• 2021

The problem of predicting a ship's form factor and associated scale effects has been subject to many investigations in recent years. In this study, an attempt is made to investigate whether the form factor is influenced by a change in the ship's speed by numerically modelling a geosim series of the KCS hull form by means of a RANS solver. The turbulence dependence of the problem is also studied by altering the closure model among three widely used approaches (the k-𝜔, k-𝜔 SST, and k-𝜀 models). The results show that at very low speeds (Froude numbers in the range of 0.02-0.06) the numerical model predicts changes in the form factor of a ship between 10% and 20%, depending on the turbulence model and scale factor choices. As the speed is increased further, the form factor exhibits little change, usually in the range of 1% or less. Simulations where the Reynolds number is changed by approximately two orders of magnitude, achieved by altering the value of viscosity, confirmed that the form factor can be considered Froude-dependent only for low speeds, predicting essentially identical values when high speed cases are considered.

• Biomolecules & Therapeutics
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• 제31권5호
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• pp.536-543
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• 2023

Phytoceramide (Pcer) is found mainly in plants and yeast. It can be neuroprotective and immunostimulatory on various cell types. In this study, the therapeutic effect of Pcer was explored using the carrageenan/kaolin (C/K)-induced arthritis rat model and fibroblast-like synoviocytes (FLS). Pcer treatment (1, 10, and 30 mg/kg/day) were given to the arthritic rats for 6 days after disease induction. Weight distribution ration (WDR), knee thickness, squeaking score, serum levels of proinflammatory mediators, and histological analysis were measured and performed to evaluate arthritic symptoms in the rat model. In interleukin (IL)-1β-stimulated FLS, proinflammatory mediators were measured after Pcer (1-30 µM) treatment. Arthritic symptoms in rats with Pcer treatment were significantly decreased at days 4 to 6 after C/K arthritis induction. Inflammation in the knee joints were also significantly decreased in rats with Pcer treatment. Furthermore, in IL-1β-stimulated FLS, the expressions of proinflammatory mediators were also inhibited by Pcer. As shown by the results, Pcer has anti-arthritic effects in the C/K rat model and in synovial cells, suggesting that Pcer has the potential to be a useful agent in arthritis treatment.

• 한국전통조경학회지
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• 제33권2호
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• pp.12-20
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• 2015

수정동 원림은 조선중기 고산 윤선도에 의해 조영된 곳으로 국문학적으로나 정원사에 있어 중요한 정원유산 이지만 최근 주변 개발로 인한 외부요인에 의한 훼손우려와 오랫동안 방치된 결과 정원 내부의 훼손이 진행되고 있어 대상에 대한 신중한 조사와 분석을 통한 정비계획이 요구된다. 본 연구의 목적은 한국 전통정원 유산인 수정동 원림을 대상으로 진정성 있고 신중한 정비방향을 수립하는 것이다. 연구의 방법으로 지역주민과 전문가들의 인터뷰와 자문, 문헌고찰, 현장조사와 정밀측량, 전문가집단의 참여를 통한 현장 고증 등을 실시하였다. 연구 결과는 다음과 같다. 첫째, 유구에 대한 핵심 권장 검토 발굴 구역을 제시하였다. 둘째, 인위적으로 조영된 환경을 대상으로 고산 당대 조성 혹은 명명된 유구와 조성시기 확인이 요구되는 유구로 구분하여 정비내용을 제시하였다. 셋째, 자연지형 요소에 대해서는 식생정비계획과 활용측면에서 간단한 시설 도입을 제시하였다. 마지막으로 고산이 정원을 즐기고 이용했을 것으로 추정되는 공간들을 중심으로 구체적인 동선과 관련 정비내용을 제시하였다.

• 한국콘텐츠학회논문지
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• 제6권11호
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• pp.85-94
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• 2006

본 연구의 목적은 보전 중심의 획일적인 국공립공원 개발방식에서 벗어나 보전개념과 함께 흥미 있는 테마를 적용하여 복합적인 개념의 자연공원 개발방안을 제시하는 것이다. 관광트랜드와 개발에 대한 요구분석 결과 대상지인 경기도 가평 연인산 도립공원의 방문객 대다수가 수도권에 거주(87%)했고, 주 이용객은 20-30대(52%)로 나타났다. 숙박시설은 독립빌라형을 가장 선호(47%)했고, 상업시설은 식음 및 판매시설에 대한 확충(65%)을 가장 우선적으로 요구하는 것으로 조사되었다. 향후 도입시설에 있어 자연생태체험(43%), 건강 휴양시설(34%)을 선호하는 것으로 나타났다. 실증분석 결과, 체험과 휴양을 핵심 컨셉으로 한 다양하고 질 높은 테마형 자연공원조성이 필요하고 환경보전을 병행해야 하겠다.

• Archives of Plastic Surgery
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• 제41권6호
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• pp.620-629
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• 2014

Keloid scars are often considered aesthetically unattractive and frustrating problems that occur following injuries. They cause functional and cosmetic deformities, displeasure, itching, pain, and psychological stress and possibly affect joint movement. The combination of these factors ultimately results in a compromised quality of life and diminished functional performance. Various methods have been implemented to improve keloid scars using both surgical and non-surgical approaches. However, it has proven to be a challenge to identify a universal treatment that can deliver optimal results for all types of scars. Through a PubMed search, we explored most of the literature that is available about the intralesional injection treatment of hypertrophic scars and keloids and highlights both current (corticosteroid, 5-fluorouracil, bleomycin, interferon, cryotherapy and verapamil) and future treatments (interleukin-10 and botulinum toxin type A). The reference lists of retrieved articles were also analysed. Information was gathered about the mechanism of each injection treatment, its benefits and associated adverse reactions, and possible strategies to address adverse reactions to provide reliable guidelines for determining the optimal treatment for particular types of keloid scars. This article will benefit practitioners by outlining evidence-based treatment strategies using intralesional injections for patients with hypertrophic scars and keloids.

• 한국실내디자인학회논문집
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• 제15권5호
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• pp.306-313
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• 2006

Digital simulation which was introduced to the architectural field due to the rapid growth of computer graphics, gave birth to a new type of contents called 'virtual reality', led by the interaction with the users and real time processing. The public attention is drawn to the virtual reality's potential as a next generational space simulation it, having the unique characteristics of 'simulation', 'interactivity', 'tole-presence', and 'immersion', is capable of taking a virtual tour of a space with a size equivalent to that of a real space, as well as proceeding with the design progress. Nonetheless, many problems impeding CPU's real time processing of an excessively loaded architectural model data have been pinpointed over the time. Yet such GPU based game engines as 'DirectX' and 'OpenGL', developed to deal with these impediments, have not been easily applied to the architectural simulation in the design process, due to the high license cost and the specific technical requirements for the system. The virtual reality has been developed and distributed centering around the gaming field, and game developers recently show a greater tendency to include level editors in the package for the expandability purpose. Thus, we plan to propose architecture simulation which utilizes level editors in this study. In addition, the compatibility of the game engine based level editors of Quake and Unreal which form the standards for the open source FPS games, based on VRML, the standard format for the virtual reality, was compared and analyzed. Taking the example of Villa Savoye of Le Corbusier, its application possibility as an architecture simulation was assessed, by measuring the extent to which the performance of such characteristic features of the virtual reality as interactivity, immersion, and tele-presence, was improved.

• 건축역사연구
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• 제18권2호
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• pp.7-26
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• 2009

The purpose of this paper is the study on the architectural characteristics revived from the roman architecture, focused on the early renaissance architecture building. The results of study are as follow: 1. The composition system of Domus which is formed of urban house in the Roman period is presented by spatial arrangement of palace architecture centering around atrium in the Renaissance period. Thus plan type of Domus is used by atrium from which is composed of peristyle from the palace and villa in the Renaissance period. 2. The circular temple in the Roman period is composed of element such as podium, stair, peristyle centering around the basic circular plan. Bramante planed to revive above elements for the Tempietto to concept from the circular temple in the Roman period. 3. The triumphal arch in the Roman period is strong monument to the independent building in the city, but thus arch is used of church facade as the important example which is composed with building elevation in the Renaissance period. 4. The composition system and element of Roman temple which is planned to rectangular plan is composed of high podium, stair, portico, prostyle and pediment. The facade plan of church is used by the partial elements and total elements perfectly from the temple in the Roman period. 5. The linearly successive and repetitive composition which is composition system and element of aqueduct arches of same dimension shows to the palace facade, arcade for gallery space and side elevation plan of S.Fracesco church. 6. Such as background of Colloseum, Rucellai palace can be called good example which is created by the new architectural form to the creative starting point from the classical architecture from.

• 건축역사연구
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• 제17권3호
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• pp.23-43
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• 2008

Seoul has been watched at its symbolic image which is the capital of one nation. since then Joseon was established. So, most of study about Seoul placed too much emphasis on like next; urban organization, palace, government office and public establishment. On the other hand, it is lacking in study of the individual building, the residential district, the change of building-lot. This study is to make up a deficiency from study of Gaokdohyung(家屋圖形site and floor plan). Gaokdohyung(家屋圖形) is drawings of building lots & houses existed in Hanseongbu漢城府(modem Seoul). It is possessed in Jangseogak and all 24 sheets. It is merely 24sheets but has many urban information in that. Housing of number 116 expressed in Gaokdohyung are consist on the house of Sadaebu士天王(noble class) Joongin中人(middle class) Sangmin常民(commoner), Villa(Byeolseo別墅) and connecting stores etc. Houses in Gaokdohyung has characteristic that most building lot is very specious and owners are variety of social position. The study of Gaokdohyung will progress through analyzing diachronic change of individual building lot & house. In the event, results of this study will help to find out change of urban tissue & architecture. So, i intend to seek for entity of urban tissue and urban house in Joseon Period differ from now, and to study out those have been changed continuously forward now.

• 한국GIS학회:학술대회논문집
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• 한국GIS학회 2010년도 춘계학술대회
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• pp.94-102
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• 2010

오늘날 지목은 토지의 이용용도나 이용형태를 결정짓는 가장 구체적인 법률적 기준이 되고 있다. 지목은 토지의 주된 사용용도에 따라 분류되기 때문에 주 사용용도가 동일하다면 모두 같은 지목으로 결정하고 있다. 동일한 "대" 지목이라 하더라도 구체적으로는 단독주택, 연립주택, 다세대주택, 빌라, 아파트, 주상복합, 상업 업무용, 나대지 등으로 다양하게 이용되고 있어 그 명확한 구분이나 분류기준 등에 있어 한계성을 가지고 있으며 녹색성장을 위한 온실가스 배출실태나 감축 또는 통계산정에 있어서 용도별 배출특성을 다양하게 분석 할 필요성이 제기되고 있다. 그래서 본 연구는 기관별 다른 분류체계를 가진 5개의 도면을 중심으로 이산화탄소 배출량을 실제로 측정하여 분석한 결과 계절별은 겨울, 봄, 가을, 여름순으로 측정 되었으며, 겨울과 여름의 가장 큰 분포특성은 1.78배, 평균 1.35배가 높게 나타났으며, 오전 9시와 15시의 기온이 약 $11^{\circ}C$ 변화할 때 22ppm으로 오후가 높게 측정되었다 용도별로 분석한 결과 단독주택에 비해 상업 업무용은 4.04배, 주상복합은 1.47배나 높게 배출되었다.

• 건축역사연구
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• 제8권4호
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• pp.95-112
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• 1999

This Study starts from a recognition that the architecture is based on the process demanded by substantial needs as well as pure theoretical logic system. So this study aims at proposing another point of view differentiating process and principle of architecture from pure theoretical logic system in the creative process of the Governor's Palace by analyzing drawings in chronological order. Even though the Governor's Palace had not been built because of discord between authorities of India and Le Corbusier, it is undoubtedly one of the best proposals which contains very concepts and ideas of later Le Corbusier's architectural intentions. In the first design stage, overall conception of the building was carried out in the sketches and drawings till Jan, 1954 and in the second stage, the elaboration of the project was pursued till Mar. 1995. The scheme tends to begin too large and general in character, becoming tighter and more complex under pressure from the client and adjustments required by the design process itself. For example, scale reduction, division and development of internal circulation system and applying his early 'Five Points'. So new solutions are searched by oscillating between compromise modifications and radically different solutions in contracting the first ideas. From all these, it is concluded that the early doctrine (Five Points) are adjusted and extended towards another stage by the use of restricted pilotis, the concept of fenetre en longueur transformed into a sub stricture of facade, sustained concept of le plan libre, les toits jardins extended towards concept of the urban area. And these formal intentions of the Governor's Place has been carried through other contemporary projects like Mill Owner's Association in 1954 and Villa Shodan in 1952.