• Natural Product Sciences
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• 제17권2호
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• pp.142-146
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• 2011

In the course of screening for antioxidant compounds by measuring the radical scavenging effect on 1,1-diphenyl- 2-picrylhydrazyl (DPPH), a total extract from the whole plant of Veronica peregrina (Scrophulariaceae) was found to show potent antioxidant activity. Subsequent activity-guided fractionation of the methanolic extract led to the isolation of six phenolic compounds including chrysoeriol (1), diosmetin (2), 4-hydroxybenzoic acid (3), apigenin (4), caffeic acid methylester (5) and protocatechuic acid (6). Their structures were elucidated by spectroscopic studies. Compounds 1-5 were isolated for the first time from this plant. Compounds 5 and 6 showed significant antioxidative effects in DPPH free radical scavenging and superoxide quenching activity assays.

• Journal of Species Research
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• 제9권4호
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• pp.375-376
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• 2020

A type specimen is the specimen originally used to name a new species; thus, it is one of the most significant materials for taxonomic study. In our study on the inventory and management of endemic species in Korea, we checked the type materials for Pseudolysimachion pusanensis (Y. Lee) Y. Lee, combination name Veronica pusanensis Y. Lee, recorded as deposited at the herbaria of the Ewha Womans University and the National Institute of Biological Resources, and failed to find any specimens. Thus, we concluded that all type specimens of V. pusanensis have since been misplaced. According to articles 9.11 and 9.13 of the International Code of Nomenclature for algae, fungi, and plants, it is necessary to select a neotype if the holotype is missing and no other original material exists. Therefore, we designate the neotype maintained in the herbarium of the National Institute of Biological Resources of the Republic of Korea.

• 정보관리연구
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• 제26권4호
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• pp.28-62
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• 1995

본 연구는 이용자 지향적인 서비스 개선방법을 모색하기 위해 끊임없이 변화하고 있는 인터넷에 대하여 전반적으로 기술하였다. 특히 정보검색 측면에서 현재 널리 이용되고 있는 Gopher, Veronica, Archie, WAIS, WWW 등의 전반적인 개념과 특성 그리고 사용방법을 설명하였다. 그리고 WWW의 웹브라우저와 검색엔진에 관해서는 실제 사용한 경험을 근거로 상세하게 설명함으로써 초보자도 필요한 장비만 갖추어진다면 인터넷을 사용할 수 있는 방법을 소개하였다.

• Natural Product Sciences
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• 제18권3호
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• pp.141-146
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• 2012

Veronica peregrina (Scrophylariaceae) has been widely used as a Korean traditional medicine for the treatment of various pathological conditions including infection, hemorrhage and gastric ulcer. In the current study, we investigated the inhibitory effect of methanolic extracts of V. Peregrina (VPM) on the LPS-mediated nitric oxide (NO) production in mouse (C57BL/6) peritoneal macrophages. NO production was significantly down-regulated by the treatment of VPM dose dependently. To evaluate the mechanism of the inhibitory action of VPM on NO production, we performed iNOS enzyme activity assay and checked the change of inducible nitric oxide synthase (iNOS) levels by Western blotting. Although VPM did not affect iNOS enzyme activity, iNOS protein expression was attenuated by VPM indicating VPM inhibits NO production via suppression of iNOS enzyme expression. In addition, VPM attenuated the expression of another pro-inflammatory mediator such as cyclooxygenase-2 (COX-2) in a dose dependent manner. We also found that VPM can reduce trypsin-induced paw edema in mice. Based on this study, we suggest that V. peregrina may be beneficial in diseases which related to macrophage-mediated inflammatory disorders.

• 식물분류학회지
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• 제36권2호
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• pp.145-151
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• 2006

제주도의 저지대 길가 공터에서 채집한 나도양귀비 (Papaver setigerium DC.)와 해발 400-800 m의 길가나 목장 내에서 채집한 좀개불알풀 (Veronica serpyllifolia L.) 등 2종을 국내 미기록 귀화식물로 보고한다. 나도양귀비는 양귀비와 유사하지만 나도양귀비는 높이 30-70 cm, 원반형의 암술머리의 직경이 열매의 직경보다 작으며, 줄기, 잎, 꽃받침 등에 강모가 산생하는 점에서 쉽게 식별된다. 좀개불알풀은 방패꽃과 공통점이 많지만 본 종이 전체적으로 소형이고, 줄기 하부의 잎이 엽병을 가지며, 거치가 있다는 점에서 구분된다.

• 식물분류학회지
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• 제51권1호
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• pp.109-114
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• 2021

Veronica nakaiana Ohwi (Plantaginaceae) is an endemic taxon on Ulleungdo Island, Korea. We report the second complete chloroplast genome sequence of V. nakaiana. Its genome size is 152,319 bp in length, comprising a large single-copy of 83,195 bp, a small single-copy of 17,702 bp, and a pair of inverted repeat regions of 25,711 bp. The complete genome contains 115 genes, including 51 protein-coding genes, four rRNA genes, and 31 tRNA genes. When comparing the two chloroplast genomes of V. nakaiana, 11 variable sites are recognized: seven SNPs and four indels. Two substitutions in the coding regions are recognized: rpoC2 (synonymous substitution) and rpl22 (nonsynonymous substitution). In nine noncoding regions, one is in the tRNA gene (trnK-UUU), one is in the intron of atpF, and seven are in the intergenic spacers (trnH-GUG~psbA, trnK-UUU, rps16~trnQ-UUG, trnC-GCA~petN, psbZ~trnG-GCC, ycf3~trnS-GGA, ycf4~cemA, and psbB~psbT). The data provide the level of genetic variation in V. nakaiana. This result will be a useful resource to formulate conservation strategies for V. nakaiana, which is a rare endemic species in Korea.

• 대한본초학회지
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• 제39권3호
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• pp.57-67
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• 2024

Objectives : The aim of this study is to evaluate the potential biological activity of Veronica incana extracts (VIE) through in vitro, ex vivo, and in vivo experiments. Methods : In vitro, we conducted analyses on the total polyphenol (TP) and total flavonoid (TF) levels, alongside DPPHand ABTS radical scavenging activities. Ex vivo evaluations on adipose tissue measured glycerol release as a marker of lipolysis. In LPS-induced RAW 264.7 cells, we quantified nitric oxide (NO) production. Following H₂O₂ induction in U2OS cells, we performed mitochondrial assays such as MitoSox and MitoTracker. Moreover, Bodipy assays were conducted in 3T3-L1 cells. In vivo, we performed anti-osteoarthritis effect of VIE against monosodium iodoacetate (MIA)-induced osteoarthritis in rats. Results : The results presented encompass a myriad of models, from cell culture to animal experiments as well as ex vivo studies. VIE demonstrated high TP and TF contents, potent DPPH and ABTS scavenging activities, and regulated glycerol release. Moreover, the inhibition of NO production in LPS-induced inflammation was notably confirmed and the reduction of lipid droplets was distinctly shown. Furthermore, in H₂O₂-induced U2OS cells, MitoSox was effectively reduced while MitoTracker noticeably increased. In vivo assays confirmed a significant increase in hindpaw weight distribution (HWD) decreased by MIA after VIE treatment. Additionally, VIE inhibited serum inflammatory cytokines (TNF-𝛼, IL-6, and IL-1𝛽) and MDA levels in joint tissue. Conclusion : In conclusion, Veronica incana exhibited various pharmacological effects including antioxidant, anti-obesity, and anti-inflammatory properties.

• 현장농수산연구지
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• 제25권1호
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• pp.36-47
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• 2023

큰산꼬리풀(V. glabrifolia Kitag.), 부산꼬리풀(V. pusanensis Y.N.Lee), 큰산꼬리풀 교배조합(V. glabrifolia Kitag. × V. Spicata 'Alba')과 시판종 교배조합(V. spicata 'Ulster Blue Dwarf × V. longifolia) 등 4종에 대한 종자 소독액의 침지 시간, 광질, 온도 및 복토 깊이가 종자의 발아에 미치는 영향을 알아보았다. 종자의 소독액 침지시간에 따른 발아율 및 발아 균일도는 부산꼬리풀 120분 침지와 나머지 종은 60분 침지에서 다소 양호하였으나 큰 차이는 없었다. 광질의 처리에 있어서 복색광(적색광+청색광)에서 큰산꼬리풀의 발아율은 92.8%, 발아 균일도는 2.3, 부산꼬리풀의 발아율은 85.9%, 발아 균일도는 3.5로 가장 양호하였으며 교배조합에서도 같은 경향을 보였다. 꼬리풀에서 4종에서 적색광의 발아율은 79.1%~95.5%, 균일도는 3.2~4.2이었고, 청색광에서는 발아율은 83.1%~100%, 균일도는 1.9~3.8로 다소 높게 나타났으며 무광상태의 발아율은 40.0~56.3%, 균일도는 5.2~6.5로 현저하게 낮아졌다. 온도 처리에 있어서 주간 25℃/야간 20℃는 최종 발아율 92.1%~100%, 발아 균일도 1.5~2.6로 주간 20℃/야간 15℃ 최종 발아율 85.5%~98.9%, 발아 균일도 1.9~3.1보다 높은 것으로 나타났다. 부산 꼬리풀의 경우 주간 25℃/야간 20℃에서 최종 발아율 92.1%, 발아 균일도가 2.6으로 항온 25℃/24시간처리의 최종 발아율 80.9%, 발아 균일도 3.8보다 최종 발아율 및 발아 균일도가 높게 나타났다. 복토 정도에 따른 발아율 및 발아 균일도는 모든 종에서 1~2mm 복토에서 발아율이 83.4%~100% 및 발아 균일도 0.6~4.2로 가장 좋았으며 4mm로 복토를 많이 하면 최종 발아율 45.2%~72.1%, 발아 균일도 4.3~5.5로 현저하게 낮아지고 배축의 길이도 3cm 이상으로 길어졌다.

• Archives of Plastic Surgery
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• 제45권4호
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• pp.390-392
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• 2018

• 한국수의병리학회:학술대회논문집
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• 한국수의병리학회 2005년도 Proceedings of The 2nd Asian Society of Veterinary Pathology Symposium(Vol.2) and 2005 Annual Meeting of The Korean Society of Veterinary Pathology(Vol.9)
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• pp.51-51
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• 2005