• Title/Summary/Keyword: Ventilation effect

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Different PEEP Effects on Lung Volume According to Underlying Lung Disease in Patients with Auto-PEEP (자가 호기말 양압(auto-PEEP)을 보인 환자에서 원인질환에 따른 PEEP적용 효과의 차이)

  • Sohn, Jang Won;Koh, Younsuck
    • Tuberculosis and Respiratory Diseases
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    • v.57 no.6
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    • pp.567-572
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    • 2004
  • Background : The effect of PEEP(ed note: Define PEEP.) on the lung volume in patients with auto-PEEP during mechanical ventilation is not even. In patients with an expiratory limitation such as COPD, a PEEP of 85% from an auto-PEEP can be used with minimal increase in the lung volume. However, the application of PEEP to patients without an expiratory flow limitation can result in progressive lung. This study was carried out to evaluate the different PEEP effects on the lung volume according to the different pulmonary diseases. Methods : Sixteen patients who presented with auto-PEEP during mechanical ventilation were enrolled in this study. These patients were divided into 3 groups: asthma, COPD and tuberculosis sequela (patients with severe cicatrical fibrosis as a result of previous tuberculosis and compensatory emphysema). A PEEP of 25, 50, 75 and 100% of the auto-PEEP was applied, and the lung volume increments were estimated using the trapped lung volume. Results : In the asthma group, the trapped lung volume was not increased at a PEEP of 25 and 50% of the auto-PEEP. This group showed a significant lung volume increment from a 75% PEEP. In the COPD group, the lung volume was increased only at 100% PEEP. In the tuberculosis sequela group, the lung volume was increased progressively from low PEEP levels. However, a significant increment of the lung volume was noted only at 100% PEEP. Conclusion : The effects of the applied PEEP on the lung volume were different depending on the underlying lung pathology. The level of the applied PEEP >50% of the auto-PEEP might increase the trapped lung volume in patients with asthma.

Comparison of Rib Fracture Location for Morbidity and Mortality in Flail Chest (늑골 골절의 위치가 동요흉의 이환율 및 사망률에 미치는 요인)

  • Byun, Chun Sung;Park, Il Hwan;Bae, Geum Suk;Jeong, Pil Yeong;Oh, Joong Hwan
    • Journal of Trauma and Injury
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    • v.26 no.3
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    • pp.170-174
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    • 2013
  • Purpose: A flail chest is one of most challenging problems for trauma surgeons. It is usually accompanied by significant underlying pulmonary parenchymal injuries and mayled to a life-threatening thoracic injury. In this study, we evaluated the treatment result for a flail chest to determine the effect of trauma localization on morbidity and mortality. Methods: Between 2004 and 2011, 46 patients(29 males/17 females) were treated for a flail chest. The patients were divided into two group based on the location of the trauma in the chest wall; Group I contained patients with an anterior flail chest due to a bilateral costochondral separation (n=27) and Group II contained patients with a single-side posterolateral flail chest due to a segmental rib fracture (n=19). The location of the trauma in the chest wall, other injuries, mechanical ventilation support, prognosis and ISS (injury severity score) were retrospectively examined in the two groups. Results: Mechanical ventilation support was given in 38 patients(82.6%), and 7 of these 38 patients required a subsequent tracheostomy. The mean ISS for all 46 patients was $19.08{\pm}10.57$. Between the two groups, there was a significant difference in mean ventilator time (p<0.048), but no significant difference in either trauma-related morbidity (p=0.369) or mortality (p=0.189). Conclusion: An anterior flail chest frequently affects the two underlying lung parenchyma and can cause a bilateral lung contusion, a hemopneumothorax and lung hemorrhage. Thus, it needs longer ventilator care than a lateral flail chest does and is more frequently associated with pulmonary complications with poor outcome than a lateral flail chest is. In a severe trauma patient with a flail chest, especially an anterior flail chest, we must pay more attention to the pulmonary care strategy and the bronchial toilet.

Clinical Review of Pediatric Adenoviral Lower Respiratory Infection (아데노바이러스에 의한 소아 하기도 감염에 대한 임상적 고찰)

  • Son, Jin-A;Lee, Sang-Il;Lee, Nam-Young;Kim, Jung-Hee
    • Pediatric Infection and Vaccine
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    • v.3 no.2
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    • pp.154-162
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    • 1996
  • Purpose : Adenoviruses(Ad) have been shown to play an important role in the etiology of severely acute respiratory diseases, particulary in infants and young children, and the occurrence of fatal outcome and chronic pulmonary sequelae in association with adenoviral infection has been a cause of great interest and concern. This report presents the resul of a retrospective analysis on 30 cases of lower respiratory infection from which adenovirus was isolated. Patients & Methods : The 30 patients in this study represent all detected cases of adenovial infection out of 240 children who were admitted to Sang Sung Medical Center between February to June 1996 showing signs and symptoms of lower respiratory tract infection. The diagnosis of adenovirus infection was based on microscopic visualization of typical cytopathic effect in HEp-2 tissue culture and used monoclonal Ab with nasopharyngeal aspiration. Results : The male/female ratio was 2:1 and the majority of age range was below 36months. Clinical diagnoses in all 30 patients were pneumonia(n=21), bronchitis and Bronchiolitis(n=5) and ARDS(n=4). We recieved the most of patients in the month of May. The chief complaints were fever(93.3%) and cough(80%) and extrapulmonary symptoms were diarrhea(n=5), seizure(n=4), abdominal pain(n=1). The mean duration of fever was $11.95{\pm}6.54$days. Physical examination on admission were crackles(73.3%), coarse breathing sounds(60%), hepatosplenomegaly(33.3%), decreased brething sounds(30%). In WBC counts, 8cases were below $4000/mm^3$ and 14 cases were above $10,000/mm^3$. In platelets counts, 4cases were below $150,000/mm^3$ and 10 cases were above $450,000/mm^3$. 21 cases were above 1 in CRP. GOT and GPT were abnormal in some cases. Chest X-ray revealed diffuse pulmonary infiltration(n=15), pleural effusion(n=6), consolidation(n=4) and hyperaeration(n=3). Seven patients were treated at the peditric intensive care unit with respiratory support and high dose of gammaglobulin. However, one patients died even through he was treated with NO ventilation and high frequency ventilation. Conclusion : Those with adenoviral pneumonia and respiratory infection having long fever duration and symptoms like bacterial pneumonia must be carefully differentiated in order to provide proper treatement and preventive measures due to possible fatal outcome.

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Effect of Mechanical Ventilation System on Improvement of Indoor Air Quality in A Newly Built Apartment and B Department Store (A신축아파트 및 B백화점에서 기계환기에 의한 실내공기질의 개선 효과)

  • Park, Jeong Ho;Lee, Sang Hyuk;Kim, Hyoung Kab
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.24 no.1
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    • pp.38-45
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    • 2014
  • 본 연구에서는 기계환기에 의한 실내공기질 개선효과를 현장실험을 통해 파악하기 위해 환기설비를 갖춘 A 신축아파트와 다중이용시설인 B 백화점을 연구 대상으로 하였다. A 신축아파트에서는 새집증후군 등 주요 실내공기오염의 원인물질인 VOCs 및 HCHO를 측정 대상물질로 선정하고 미환기 상태에서 16가구에서 전반적인 신축아파트의 실내공기오염 특성을 파악하였으며, 이중 상대적으로 TVOC 농도가 높은 2가구를 대상으로 환기전후의 농도 특성을 파악하였다. B 백화점에서는 $CO_2$ 및 HCHO를 대상물질로 선정하고 1~7층별로 미환기시와 기계환기 1시간 이후의 농도 특성을 통해 환기에 의한 저감율을 파악하였으며, 이후 환기시설 정상가동 상태에서 3년간 실내공기오염물질의 농도 특성을 파악하였다. 미환기 상태에서 A 신축아파트의 VOCs 및 HCHO 농도는 일부 지점에서는 에틸벤젠, 자일렌 등의 농도가 실내환경기준을 초과하고 있었다. 특히 환기전후의 TVOC 농도 특성은 A-1 지점의 경우 미환기시 $3,547{\mu}g/m^3$에서 환기시 $961{\mu}g/m^3$ 그리고 A-2 지점의 경우 미환기시 $3,117{\mu}g/m^3$에서 환기시 $594{\mu}g/m^3$으로 환기에 의해 각각 73%, 81% 저감율이 나타났다. 또한 개별 VOCs 및 HCHO물질별 환기에 의한 저감율은 31.4~96.7%로 나타났으며, 환기이후 모든 물질이 실내기준보다 훨씬 낮은 수준으로 나타났다. B 백화점에서는 평균 $CO_2$ 농도는 미환기시 855 ppm에서 기계환기 1시간 이후 580 ppm으로 약 32% 저감되었으며, HCHO의 평균농도도 $251{\mu}g/m^3$에서 $70.3{\mu}g/m^3$으로 약 72%의 저감되는 것으로 나타났다. 이후 환기시설 정상가동 상태에서 3년간 실내공기질의 측정결과 지속적으로 실내환경 기준을 만족하였다. 최근 실내공기질 개선을 위해 다양한 개선 방법이 소개되고 있으나, 이중 기계환기는 신축아파트 및 다중이용시설 등에서 실내공기질을 실내환경기준 이하로 지속적이고 쾌적하게 유지할 수 효과적 방법으로 고려된다.

Effect of Season on Volatile Organic Compounds and Volatile Fatty Acids Concentration in finishing Pig Slurry to Grassland (초지환원용 비육돈 슬러리의 계절에 따른 휘발성유기물과 휘발성지방산 농도 분석연구)

  • Cho, Sung Back;Yang, Seung Hak;Lee, Kyung Tai;Park, Sung Kwon;Han, Duck Woo;Choi, Dong Yun;Hwang, Ok Hwa
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.34 no.2
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    • pp.125-128
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    • 2014
  • The objective of this study is to investigate the changes in levels of odorous compounds in pig slurry during different seasons. Slurry from pens of finishing pigs was sampled every 4-wk and concentration of odorous compounds was analyzed. There was no difference in the range of phenols level (123 to 156 ppm) during spring (April to May), summer (July to August) and fall (October to November). The concentration of indoles was higher (P<0.05) during spring (14.3 ppm) than summer and fall (5.4~7.6 ppm). Level of BCFA ranging from 727 to 1,194 ppm was not different at any season. Among SCFA, there was no difference in propionic acid during any season but levels of acetic acid and butyric acid were highest (P<0.05) during spring season. Concentration of odorous compounds in pig slurry was highest during spring season. Interestingly, it tended to be lower during summer season compare to fall. This result might be due to relatively lower ventilation rate in order to maintain a constant temperature during spring season. Further study will be necessary to determine the relationship between the concentration of odorous compounds and ventilation system.

Effects of Shading Rate and Method of Inside Air Temperature Change in Greenhouse (차광율 및 차광방법이 온실내부의 온도변화에 미치는 영향)

  • 이석건;이현우;김길동;이종원
    • Journal of Bio-Environment Control
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    • v.10 no.2
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    • pp.80-87
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    • 2001
  • This study was conducted to provide basic data for the design of shading facility of greenhouse. The proper distance between external shading screen and roof surface, transmissivity of shading materials, and shading effects of external and internal shadings were analyzed. About a distance of 10 cm between inclined external shading screen and roof surface was enough to guarantee the external shading effect in the greenhouse without roof vent. The inside temperature of greenhouse installed with 85% internal shading screen was lower the maximum of 4$^{\circ}C$ and mean of 2$^{\circ}C$ than that with 55% internal shading screen in both natural ventilation and no ventilation condition. The difference of soil temperature between shading and no shading greenhouse was great, but the difference by shading rate or shading method was small. The performance of external shading for controlling inside temperature down was superior to that of the internal shading. The externally inclined shading screen parallel to the roof surface of greenhouse was more effective than the externally horizontal shading screen in controlling inside temperature of greenhouse without roof vent.

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Stabilization of Soil Moisture and Improvement of Indoor Air Quality by a Plant-Biofilter Integration System (식물-바이오필터에 의한 토양수분 안정화 및 실내 공기질 향상)

  • Lee, Chang Hee;Choi, Bom;Chun, Man Young
    • Horticultural Science & Technology
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    • v.33 no.5
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    • pp.751-762
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    • 2015
  • This study was performed to investigate the stability of soil moisture in controlling air ventilation rate within a horizontal biofilter, and to compare removal efficiency (RE) of indoor air pollutants including fine dust, volatile organic compounds (VOCs), and formaldehyde (HCHO), depending on whether dieffenbachias (Diffenbachia amoena) were planted in the biofilter. The relative humidity, air temperature, and soil moisture contents showed stable values, regardless of the presence of D. amoena, and the plants grew normally in the biofilter. REs for number of fine dust particles (PM10 and PM2.5) within the biofilter filled with only soil were at least 30% and 2%, respectively. REs for number of fine dust particles (PM10 and PM2.5) within the biofilter including the plants were above 40% and 4%, respectively. RE for fine dust (PM10) weight was above 4% and 20%, respectively, in the biofilter containing only soil or soil together with plants. In the case of the biofilter filled with only soil, REs for xylene, ethylbenzene, toluene or total VOC (T-VOC) were each more than 63%; however, REs for benzene and formaldehyde (HCHO) were above 22% and 38%, respectively. In the biofilter with the plants, REs for xylene, ethylbenzene, toluene, and T-VOC were each above 72%, and REs for benzene and HCHO were above 39%. Thus, RE of the biofilter integrated with plants was found to be higher for volatile organic compounds than for fine dust. Hence, the biofilter was very effective for indoor air quality improvement and the effect was higher when integrated with plants.

A study on the effect of gusty wind on smoke control performance in road tunnel (돌풍이 도로터널의 제연성능에 미치는 영향 연구)

  • Baek, Doo-San;Cho, Hyeon-Seok;Lee, Seung-Chul
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.24 no.1
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    • pp.95-108
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    • 2022
  • The increase in the use time of tunnel users due to the lengthening of the road tunnel may increase the evacuation time in case of fire, resulting in a large number of casualties. In order to reduce the casualties caused by fire, the "Road Tunnel Design Manual, Part 6 Tunnel" and "Road Tunnel Disaster Prevention Facility Installation and Management Guidelines" stipulate that ventilation facilities should be installed along with the extension of the tunnel. The ventilation system design factor considers the wind speed of the external natural wind to be at least 2.5 m/s, and it is applied upward according to the characteristics of the tunnel. As a result of analyzing the five-minute average wind speed data in the Daegwallyeong region for the past 6 years, it was analyzed that 15.8% of the windy days were winds of 10 m/s or more, and the maximum was 20 m/s. Therefore, in this study, when a fire occurs in a tunnel, the pattern of natural wind flowing into the tunnel and the backlayering distance of the tunnel fire smoke according to the maximum wind speed were analyzed. As a result, it was analyzed that a backflow of up to 490 m occurs when a gust of 20 m/s blows.

Analysis of the Irradiated Solar Heat Effect on Indoor Thermal Environment of the Top Floor Units of Apartment Houses in the Summer - On Condition that All Openings of the Units are Opened - (공동주택의 하절기 자연환기 시 지붕면 일사수열이 최상층 실내온열환경에 미치는 영향 분석)

  • Choi, Dong-Ho
    • Journal of the Korean Solar Energy Society
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    • v.25 no.1
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    • pp.45-55
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    • 2005
  • In the summer, the irradiated solar heat gain through the roof has an effect on the thermal environment of the top floor units of apartment houses. This paper investigated the differences of the indoor air temperature, globe temperature and thermal comfort index between the top floor unit and the middle floor unit by measuring them at the sample units on the condition that all the openings of the units are opened. The purpose of this paper is to provide quantitative data about the irradiated solar heat gain during the summertime through the roof of an apartment house and these data to be the source to reevaluate the appropriate roof insulation efficiency. From this study, we obtained three brief results as follows. Indoor air temperature difference between the two sample units shifts a day. Indoor air temperature at the top floor unit is $0{\sim}1.8^{\circ}C$ higher than that of the middle floor unit from 12:00 p.m. to 12:00 a.m. and $0{\sim}2.8^{\circ}C$ lower from 12:00 a.m. to 12:00 p.m. The evaluation of the indoor thermal comfort index and the globe temperature shows similar results as the indoor air temperature measuring. Results of this experiment verified the actual existence of indoor air temperature difference between the top floor unit and the middle one and this difference comes from the heat storage of the roof.

Risk assessment of di(2-ethylhexyl) phthalate in the workplace

  • Kim, Hyeon-Yeong
    • Environmental Analysis Health and Toxicology
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    • v.31
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    • pp.11.1-11.6
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    • 2016
  • Objectives A hazard assessment of di(2-ethylhexyl) phthalate (DEHP), a commonly used workplace chemical, was conducted in order to protect the occupational health of workers. A literature review, consisting of both domestic and international references, examined the chemical management system, working environment, level of exposure, and possible associated risks. This information may be utilized in the future to determine appropriate exposure levels in working environments. Methods Hazard assessment was performed using chemical hazard information obtained from international agencies, such as Organization for Economic Cooperation and Development-generated Screening Information Data Set and International Program on Chemical Safety. Information was obtained from surveys conducted by the Minister of Employment and Labor ("Survey on the work environment") and by the Ministry of Environment ("Survey on the circulation amount of chemicals"). Risk was determined according to exposure in workplaces and chemical hazard. Results In 229 workplaces over the country, 831 tons of DEHP have been used as plasticizers, insecticides, and ink solvent. Calculated 50% lethal dose values ranged from 14.2 to 50 g/kg, as determined via acute toxicity testing in rodents. Chronic carcinogenicity tests revealed cases of lung and liver degeneration, shrinkage of the testes, and liver cancer. The no-observed-adverse-effect level and the lowest-observed-adverse-effect level were determined to be 28.9 g/kg and 146.6 g/kg, respectively. The working environment assessment revealed the maximum exposure level to be $0.990mg/m^3$, as compared to the threshold exposure level of $5mg/m^3$. The relative risk of chronic toxicity and reproductive toxicity were 0.264 and 0.330, respectively, while the risk of carcinogenicity was 1.3, which is higher than the accepted safety value of one. Conclusions DEHP was identified as a carcinogen, and may be dangerous even at concentrations lower than the occupational exposure limit. Therefore, we suggest management of working environments, with exposure levels below $5mg/m^3$ and all workers utilizing local exhaust ventilation and respiratory protection when handling DEHP.