• Biomolecules & Therapeutics
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• v.20 no.4
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• pp.406-412
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• 2012

This study was performed to examine the hepatoprotective effect of isorhamnetin-3-O-galactoside, a flavonoid glycoside isolated from Artemisia capillaris Thunberg (Compositae), against carbon tetrachloride ($CCl_4$)-induced hepatic injury. Mice were treated intraperitoneally with vehicle or isorhamnetin-3-O-galactoside (50, 100, and 200 mg/kg) 30 min before and 2 h after $CCl_4$ (20 ${\mu}l/kg$) injection. Serum aminotransferase activities and hepatic level of malondialdehyde were significantly higher after $CCl_4$ treatment, and these increases were attenuated by isorhamnetin-3-O-galactoside. $CCl_4$ markedly increased serum tumor necrosis factor-${\alpha}$ level, which was reduced by isorhamnetin-3-O-galactoside. The levels of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and heme oxygenase-1 (HO-1) protein and their mRNA expression levels were significantly increased after $CCl_4$ injection. The levels of HO-1 protein and mRNA expression levels were augmented by isorhamnetin-3-O-galactoside, while isorhamnetin-3-O-galactoside attenuated the increases in iNOS and COX-2 protein and mRNA expression levels. $CCl_4$ increased the level of phosphorylated c-Jun N-terminal kinase, extracellular signal-regulated kinase and p38, and isorhamnetin-3-O-galactoside reduced these increases. The nuclear translocation of nuclear factor kappa B (NF-${\kappa}B$), activating protein-1, and nuclear factor erythroid 2-related factor 2 (Nrf2) were significantly increased after $CCl_4$ administration. Isorhamnetin-3-O-galactoside attenuated the increases of NF-${\kappa}B$ and c-Jun nuclear translocation, while it augmented the nuclear level of Nrf2. These results suggest that isorhamnetin-3-O-galactoside ameliorates $CCl_4$-induced hepatic damage by enhancing the anti-oxidative defense system and reducing the inflammatory signaling pathways.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.35 no.3
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• pp.133-144
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• 2017

Recently, weather information is getting closer to our real life, and it is a very important factor especially in the transportation field. Although the damage caused by the abnormal climate changes around the world has been gradually increased and the correlation between the road risk and the possibility of traffic accidents is very high, the domestic research has been performed at the level of basic research. The Purpose of this study is to develop a risk map for the road hazard forecasting service of weather situation by linking real - time weather information and traffic information based on accident analysis data by weather factors. So, we have developed a collection and analysis about related data, processing, applying prediction models in various weather conditions and a method to provide the road hazard map for national highways and provincial roads on a web map. As a result, the road hazard map proposed in this study can be expected to be useful for road managers and users through online and mobile services in the future. In addition, information that can support safe autonomous driving by continuously archiving and providing a risk map database so as to anticipate and preemptively prepare for the risk due to meteorological factors in the autonomous driving vehicle, which is a key factor of the 4th Industrial Revolution, and this map can be expected to be fully utilized.

• Journal of the Korean Institute of Intelligent Systems
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• v.21 no.3
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• pp.383-388
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• 2011

This paper presents to study the accuracy improvement of the laser navigation using FIS(fuzzy inference system) and the reliability. As wireless guidance system, the top-mounted laser with the laser navigation can rotate $360^{\circ}$ with phototransistor or other optical sensors that read the return signal from reflectors mounted at the perimeter of the workspace. The type of major existing guidance systems is a wire guidance system. Because they have high accuracy and fast response time, they are used to most industries. However, their installation cost is very expensive and maintenance is very difficult because their sensors are placed approximately 1 inch below the ground or embedded in the floor. To solve those problems, the laser navigation was developed as a wire guidance system. It does not need to reconstruct a floor or ground. And it can reduce costs of installation and maintenance because changing the layout is easy. However, it is difficult to apply to an industrial field because it is easily affected by disturbances which cause loss and damage of data, and has slow respond time. Therefore, we study the accuracy improvement of the laser navigation. The proposed method is a correction method using reliability of the laser navigation. here, reliability is calculated by FIS which is designed with the analyzed characteristics of the laser navigation. For performance comparison, we use original position data form the laser navigation and position data corrected by original reliability from the laser navigation. In experimental result, we verified that the performance of the proposed method compared the others is improved by about 50% or more.

• Journal of the Korean Association of Geographic Information Studies
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• v.18 no.1
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• pp.74-89
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• 2015

The objective of this study is to present countermeasures for mitigation of flood damage with inundation analysis considering the effect of inland and river flood and prediction of flood inundation area, depth and time against emergencies caused by abnormal flood and local torrential rainfall. In this study, 2-D inundation analysis was fulfilled on the basis of river flood analysis applying to HEC-HMS and FLDWAV model and inundation analysis applying to SWMM model for the area of Shineum-dong, Gimcheon-si. Also expected inundation depth and area about probable rainfall of 100 and 200 years frequency were suggested. If expected inundation depth and flooding area is presented on the basis of this inundation analysis considering the effect of inland and river flood, it would be an important preliminary data to establish structural and nonstructural countermeasures for flood prevention. Also if flood risk map is prepared based on the result of inundation analysis, it would be useful to evacuate residents in high-risk area and regulate road and vehicle.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.32 no.5
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• pp.313-322
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• 2019

Recently, there have been frequent occurrences of bridge fires. Fires in cable-supported bridges can damage and brake cables due to high temperatures. In this study, fire scenarios that can occur on cable-supported bridges were set up. In addition, based on the results of vehicle fire tests, a fire intensity model was proposed and cable heat transfer analyses were performed on a target bridge. The analyses results demonstrated that temperature rises were identified on cables with a smaller cross-sectional area. Furthermore, vehicles other than tankers did not exceed the fire resistance criteria. When the tanker fire occurred on a bridge shoulder, the minimum diameter cable exceeded the fire resistance criteria; the height of the cable exceeding the fire resistance criteria was approximately 14 m from the surface. Therefore, the necessity of countermeasures and reinforcements of fire resistance was established. The results of this study confirmed that indirect evaluation of the temperature changes of bridge cables under fire is possible, and it was deemed necessary to further study the heat transfer analysis considering wind effects and the serviceability of the bridge when the cable temperature rises due to fire.

• Journal of the Korea institute for structural maintenance and inspection
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• v.23 no.3
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• pp.103-110
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• 2019

Damage to the pavement system due to various causes will be required rapid repair work for reopening the vehicle traffic. The magnesium oxide phosphate composite(MPC) has a short curing time and is capable of early compressive strength development, is suitable for rapid repair materials. The aim of this study was to evaluate the hardening and compressive strength characteristics of MPC according to the water-binder (W / B) ratio and magnesium-phosphate(M / P) ratio in order to develop repair materials consisted with light burned magnesia and potassium dihydrogen phosphate. In order to ensure the workability in the field application, the difference of mechanical properties according to standard sand and ordinary sand and performance of retards were evaluated. The mix proportion with W/B ratio was about 35% and the M/P ratio was about 1.0 ~ 1.2 has a superior perfomance with strength and hardening condition. Especially, the strength of composite at only 1 day curing with W/B ratio of 0.35 and the M/P ratio of 1.2 was shown the higher than 25.0 MPa. Boric acid as a retarder was found to be suitable for ensuring the working time, and the purity of magnesium oxide was about 90 ~ 95%, which is effective for ensuring curing time and strength.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.7
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• pp.20-25
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• 2019

In this paper, the structural weakness analysis and quality improvement of small fixed wing UAV of the hard landing type were studied. Unlike conventional aircraft, small UAV does not use runways because of its small size. Instead, small UAV use hand launch takeoff and hard landings. This type has many operational advantages because it can take off and land in a narrow space. But, the hard landing has a strong impact on the structure of the UAV and can cause serious damage. In order to analyze the exact cause of this phenomenon, the structural analysis was carried out using the 3D structural analysis program (ABAQUS) to identify the location of the fracture. And to improve the accuracy of the structural analysis, properties of the material were obtained through specimen test. As a result of the analysis, structural weaknesses were identified and improved. Thus, the validity of the study was verified by demonstrating the quality of enhanced structure through a real impact test at a higher level of 1.5 times the maximum impact during operation.

• Journal of The Korean Society For Urban Railway
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• v.6 no.4
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• pp.327-337
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• 2018

Since the track of the ballastless steel plate girder bridge is connected to a main girder without a deck and a ballast, the impact generated by train passage is transferred directly to bridge main members, and it can cause frequent damage of the bridge as well as higher noise and vibration level. Applying the CWR (Continuously Welded Rail) technology can reduce this structural problems, and, to this end, it is necessary to understand the characteristics of factors influencing vehicle-track or track-bridge interaction. In this paper, experimental study results are presented for examining the longitudinal resistance characteristics of the track, including a rail fastener, a sleeper fastener, and a track skeleton, installed on a ballastless steel plate girder bridge. The experiment is conducted using a disposed bridge from service, which is transported to a laboratory. The experimental results show that the rail fastener satisfies the performance criteria of the longitudinal resistance presented in KRS TR 0014-15, and the longitudinal resistance of old and new type sleeper fasteners is higher than the values provided in the existing research. Also, the unloaded longitudinal resistance of the ballastless track is between the ballast and the concrete tracks.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.12
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• pp.603-611
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• 2020

Potholes on the road directly affect drivers' safety, satisfaction, and vehicle damage. Thus, real-time detection and response are required. Increasing frequency of patrols allows for potholes to be detected and responded to quickly, but this takes much manpower, money, and time. In addition, potholes have different occurrence characteristics depending on the rain conditions, so it is necessary to consider the optimal frequency from an economic and road-service perspective. Therefore, a quantitative analysis was done on the effects of rainfall on the occurrence characteristics of potholes. Information on the persistence, impact of rainfall intensity, and weather information was collected over a long period. Based on the results, a risk-based, optimized, and changeable road-patrol strategy is presented. The analysis results show that the probability of pothole occurrence increases by 2.4 times in rainy weather. Furthermore, the impact continues for 3 days even after the rain stops. The probability of pothole occurrence increases by 0.46% per 1 mm of rainfall, and the occurrence characteristics react sensitively to even a small amount of rain of around 1 mm. It was concluded that road patrol is required at least once every three days for an effect-free period, while twice a day is needed for the "sphere of influence" period to achieve a 95% reliability level.ys for effect-free period, while twice a day for sphere of influence period to satisfy 95% reliability level.

• The Journal of the Korea institute of electronic communication sciences
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• v.16 no.4
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• pp.771-782
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• 2021

Regular or irregular situations such as traffic accidents, damage to road facilities, maintenance or repair work, and vehicle breakdowns occur frequently on highways. It is required to provide traffic services to drivers by promptly recognizing these regular or irregular situations, various techniques have been developed for rapidly collecting data and detecting abnormal traffic conditions to solve the problem. We propose a method that can be used for verification and demonstration of unexpected situation algorithms by establishing a system and developing algorithms for detecting unexpected situations on highways. For the detection of emergencies on expressways, a system was established by defining the expressway contingency and algorithm development, and a test bed was operated to suggest a method that can be used for verification and demonstration of contingency algorithms. In this study, a system was established by defining the unexpected situation and developing an algorithm to detect the unexpected situation on the highway, and a method that can be used verifying and demonstrating unexpected situations. It is expected to secure golden time for the injured by reducing the effectiveness of secondary accidents. Also predictable accidents can be reduced in case of unexpected situations and the detection time of unpredictable accidents.