• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 한국소음진동공학회 2014년도 추계학술대회 논문집
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• pp.377-384
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• 2014

The requirement of acoustic material which is used in underwater environment more increases. The material is used to reduce acoustic signature and radiate noise for underwater vehicle. Underwater acoustic material was made by viscoelastic material such as a rubber and a polyurethane etc. The mechanical and acoustic characteristics of these material change with hydrostatic pressure. In order to increase an acoustic performance according to hydrostatic pressure, several kinds of scatterers were added to viscoelastic material. In this paper, acoustic modelling and analysis techniques of underwater acoustic material with hydrostatic pressure were introduced and proposed. The specimens for pulse tube test were made and echo reductions were calculated and measured with hydrostatic pressure. Also the characteristics of echo reduction of the specimens with hydrostatic pressure were obtained and discussed.

• Journal of the Korean Society of Visualization
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• 제8권1호
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• pp.39-45
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• 2010

The optimal design is needed for the blade geometry of the quad-rotor blades which is mainly used for Unmanned Aerial Vehicle. To do this, it is important to analyze the wakes under the blades. In the present study, the flow around the rotating blades was analyzed using PIV(Particle Image Velocimetry) and CFD(Computational Fluid Dynamics). The maximum axial velocity was measured at about 60% position toward the radial direction of the blade. The positions of vorticities in the test section obtained by PIV and CFD were turned out to be almost alike. The values in the difference of pressure coefficients at the upper and the lower blades were increased depending on the radial direction. Then, the values were decreased at the blade tip. The data of the flow analysis in the present study are expected to be served as the design of blades and ducts for the thrust improvement in the future.

• Biomolecules & Therapeutics
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• 제5권4호
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• pp.380-383
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• 1997

CJ-50001 is a recombinant granulocyte-colony stimulating factor (rG-CSF) developed by Cheil Jedang R&D Center. The effects of CJ-50001 on the increase of peripheral neutrophil count following intravenous and subcutaneous single administration at a dose of 20$\mu$g/kg in normal ICR mice and SD rats, respectively, were compared with those of Grasin, a control drug. Both CJ-50001 and Grasin significantly increased the peripheral neutrophil number in four treatment groups and the maximum number of neutrophil was achieved at 12 to 18 h in rats and mice, respectively. The dose dependency test was studied for CJ-50001 only in normal mice by intravenous or subcutaneous administration. When administered i.v or s.c at the various doses in normal mice, CJ-50001 significantly increased the neutrophil number over the dose of 160 ng/kg, compared with the vehicle control group. From these results, it was concluded that CJ-50001 showed efficacy similar to Grasin in the peripheral neutrophil count increase.

• Biomolecules & Therapeutics
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• 제9권4호
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• pp.298-306
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• 2001

To develop a novel transdermal delivery system of loxoprofen (LP), a potent antiinflammatory and analgesic agent, the effects of vehicle composition and drug loading dose on the skin permeation property were investigated. And in vivo skin absorption property studied by analysing the $C_{max}$ and AUC was investigated after applying the developed plaster systems on rabbit back skin. Addition of isopropyl myristate (IPM) and IPM-diethylene glycol monoethyl ether (DGME) cosolvent in the plaster showed higher permeation rates than those from propylene glycol laurate-DGME cosolvent systems. As the concentration of LP in the plaster increased from 0.56 mg/$\textrm{cm}^2$ to 1.19 mg/$\textrm{cm}^2$, the drug release and skin permeation rates increased linearly. At loading dose of 1.19 mg/$\textrm{cm}^2$, the flux reached 35.6 $\mu$g/$\textrm{cm}^2$/hr. New LP plasters showed a good adhesive property onto skin, and showed no crystal formation. The AU $C_{0-24hr}$ and $C_{max}$ after dermal application of LP plaster (60 mg/70 $\textrm{cm}^2$) were found to be 6951$\pm$230 ng.hr/ml and 400$\pm$44 ng/ml, respectively. And the plasma concentration maintained above 300 ng/ml up to 24 hr period. In the carrageenan-induced rat paw edema test, LP plaster showed similar inhibition rate with marketed ketoprofen (Ketoto $p^{R}$) plaster.aster.r.

• Biomolecules & Therapeutics
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• 제5권4호
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• pp.376-379
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• 1997

The peripheral neutrophil recovery test was conducted to determine the efficacy of CJ-50001, a drug developed in Cheil Jedang R&D center as a recombinant granulocyte-colony stimulating factor (rG-CSF). Grasin was used as control drug. CJ-50001 and Gratin were subcutaneously administered to ${\gamma}$-ray irradiated mice for 21 days at a dose of 10$\mu$g/kg after bone marrow transplantation and the recovery of neutrophil number was examined on the days of 9, 13, 17, and 21 after the drug administration. It was observed that the peripheral neutrophil number of the vehicle control group was recovered to the normal level on the day of 13 after the transplantation whereas the group administered with CJ-50001 and Grasin respectively, showed the normal level of peripheral neutrophil number on 9th day after the bone marrow transplantation. The number of peripheral neutrophils reached the highest level on the 21 st day of drug administration, and was recovered to the normal level on the 4th day after ceasing of the drug administration (on the 25th day of the transplantation). Thus, it was presumed that CJ-50001 showed efficacy similar to Grasin on the peripheral neutrophil recovery after bone marrow transplantation.

• Korean Journal of Veterinary Research
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• 제34권2호
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• pp.375-379
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• 1994

A teratogenicity test of 'folpet' was carried out in the developing chick embryos to investigate and validate the safety of rural environmental hazardous materials. Folpet was administered to chick embryos' yolk sac at a rate of 0.1mg and 0.01mg per SPF eggs at 96 hours of incubation. The morphological changes were examined. Fertility ratio of SPF eggs used was 94.9%. Hatching rate of untreated control group was 74.4% and the group dosed with 100ul of corn oil into the yolk sac was 70.0%. The $LD_{50}$ of folpet was 0.663mg/100ul/egg. After hatching, mean body weight, body length, claw length and beak length of high and low dose administered groups were not significantly different from untreated and vehicle control group. There was no abnormal appearence in all the groups. Therefore it seems that, within the doses applied, folpet dose not induce potential teratogenicity in the developing chick embryos.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2008년도 추계학술대회 논문집
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• pp.353-356
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• 2008

HEV(Hybrid Electrical Vehicle) is considered as one of the next generation vehicles. To develop the HEV, there must be a reliable simulator, by which the capacities of the power resources are tested, and the parameters of the HEV are optimized before developing the real model of the HEVs. This process can save the money for designing the HEV system and improve the system without experiments. Matlab Simulink is familiar to mechanical engineers and the program can simultaneously provide a system model and a controller in one program. Nowadays, the Simdriveline toolbox which is used for analysis a power-train system is applied to build a dynamic model for a HEV system. In this study, we make a HEV simulator with the Simdriveline toolbox and develop a controller. There are two simple strategies, applied to the controller. One strategy includes a power split ratio and a shift map which are created by user. Other strategy calculated an appropriate amount of resource's torque along specific results, and this is useful when users can't develop a fitting controller. The methodologies for configuring the simulator and its control system are presented in this paper.

• Transactions of the Korean Society of Automotive Engineers
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• 제21권1호
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• pp.61-67
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• 2013

In this paper, it was studied how the critical speed which could occur hot judder due to disk temperature. Through the dynamometer experiment, we measured the critical velocity and surface temperature when the hot judder occur on the disk break. Also with the critical velocity theory equation and the temperature change graph of factors which used in the equation, we was induced experiment equation including theory equation and experiment values. And it has compared with the method which approach as linea. From this, we predicted the change of critical speed which could occur hot judder due to disk temperature. In addition, critical speed graph has compared with actual driving speed and disc temperature at a vehicle test. Therefore it was estimate to possibility of arising hot judder.

• Applied Chemistry for Engineering
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• 제25권6호
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• pp.639-644
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• 2014

Domestic vehicle companies have been selling genuine engine oils with higher price than that of the same grade of regular engine oils. In this study, our group investigated the properties of engine oils for 14 kinds of the genuine and equivalent regular engine oil (KS product) species under a fresh as well as used condition recovered after 10,000 km driving. From analytic results, genuine engine oils had similar physical properties to regular engine oils under the fresh condition. But recovered regular engine oils had better properties in lubricity, kinematic viscosity and acid number change than those of recovered genuine engine oils.

• Proceedings of the KAIS Fall Conference
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• 한국산학기술학회 2009년도 춘계학술발표논문집
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• pp.244-248
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• 2009

본 논문에서는 만타형상의 무인잠수정의 운동성능과 제어기설계에 대한 성능을 확인하기 위한 수학모델을 정립하여 시뮬레이션 프로그램을 개발하였다. 본 논문에 사용된 수학모델은 6자유도 운동방정식을 이용하여 Matlab / Simulink를 이용하여 시뮬레이션 프로그램을 개발하였다. 개발된 시뮬레이션 프로그램을 이용하여 만타형상무인잠수정(Manta-type unmanned underwater test vehicle)의 동역학적 운동성능을 해석하였으며, 무인잠수정의 제어성능을 해석하기 위하여 PID(비례-미분-적분)제어기와 슬라이딩모드(Sliding mode)제어기를 설계하여 만타형상무인잠수정의 제어 성능을 해석하였다. 설계된 제어기는 무인잠수정의 수심제어와 방향각제어에 사용되었다. 설계된 제어기의 성능을 확인하기 위하여 미국 해군대학원(Naval Postgraduate School)의 AUV II와 비교하였다. 설계된 수심제어와 방향각 제어기를 이용하여 만타형무인잠수정의 설계 목표에 부합하는 항해제어시뮬레이션을 실시하였다.