• Title/Summary/Keyword: Vascular stiffness

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Effects of Chungpyesagan-tang on arterial stiffness and pulse pressure in acute stroke patients (청폐사간탕(淸肺瀉肝湯)이 급성기 중풍환자의 동맥경직도 및 맥압에 미치는 영향)

  • Park, Young-Min;Hong, Jin-Woo;Shin, Won-Jun;Jeong, Dong-Won;Kim, Seok-Min;Bae, Hyung-Sup;Kim, Young-Suk;Moon, Sang-Kwan;Jung, Woo-Sang;Cho, Ki-Hoo
    • The Journal of Internal Korean Medicine
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    • v.27 no.2
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    • pp.416-428
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    • 2006
  • Objectives : Arterial stiffness and pulse pressure are related to cardiovascular and cerebrovascular survival and longevity. This study is aimed at examining the effects of Chungpyesagan-tang on arterial stiffness and Pulse pressure in acute stroke Patients. Methods: The subject of this study was acute strike Patients within 1 week after ictus, with Cardio-ankle vascular index(CAVI) higher than 9.0. They were divided into two groups: A treatment group (n=44) and a control group(n=46). For two weeks, Chungpyesagan-tang was given to the former, other herbal medicines to the latter. used for stroke patients for the control group for 2 weeks. At the end of first and second week, CAVI, pulse Pressure, National Institute of Health stroke scale(NIHSS), Modified Barthel Index(MBI) were measured. Serum lipid Profile, aspartate transaminase(AST), alanine transaminase(ALT). blood urea nitrogen(BUN), creatinine were also measured at the end of the study. Results : After 2 weeks, CAVI and Pulse Pressure in Chungpyesagan-tane group were significantly tower than those in the control group(P<0.05). NIHSS and MBI were improved in both groups. But there was no significant difference between the treatment group and the control group in terms of the NIHSS and MBI. Conclusions : We suggest Chungpyesagan-tanghas desirable effects on arterial stiffness and Pulse Pressure of acute stroke patients. It can improve morbidity and mortality of patients on the basis of influencing vascular stiffness and increased pulse pressure.

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The Effect of Magnetic Field Direction on the EEG and PPG Obtained from Pulsed Magnetic Stimulus at Acupoint PC9

  • Kim, Sun-Wook;Lee, Jin-Yong;Lee, Hyun-Sook
    • Journal of Magnetics
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    • v.16 no.3
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    • pp.259-262
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    • 2011
  • Compared to acupuncture, the pulsed magnetic field (PMF) stimulus is a useful tool for treatment of many physical conditions and health maintenance due to its advantages as a noninvasive and nontoxic medical treatment. The purpose of this study was to investigate the effect of PMF stimulus direction at PC9 on the alpha activity of electroencephalogram (EEG) and vascular aging calculated from photoplethysmograph (PPG). It can be concluded that the direction of PMF stimulus affects the increase of alpha activity of EEG and PPG, indicating the vascular stiffness and the sclerosis level of blood vessels weakly relevant to the direction of PMF stimulus.

Improvement of a characteristic point detection algorithm of arterial pulse (동맥맥파의 특징점 검출 알고리즘 개선에 관한 연구)

  • Jeon, Young-Ju;Lee, Jeon;Kim, Jong-Yeol;Lee, Lark-Beom;Im, Jae-Jong
    • Proceedings of the KIEE Conference
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    • 2007.07a
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    • pp.1916-1917
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    • 2007
  • Aortic AIx(augmentation index) has been used to measure aortic stiffness and evaluate ventricular load quantitatively. Algorithm for the detection of augmentation point gradually increases the differential order to detect inflection point rather than detects the distinctive point that appears after a specific time. Developed algorithm for AIx is proved to provide more accurate results than the ones developed by previous studies with the deviation from $-11.5{\pm}14.34$ points to $-3.75{\pm}1.26$ points. Results could provide the basis for the measurement of aortic stiffness using easily-measurable radial artery pulse waves, and could be extended to develop a system for early diagnosis of various vascular diseases.

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Relationship between Arterial Stiffness and Physical Activity Level Assessed by International Physical Activity Questionnaire­short form (IPAQ­SF) in the Elderly (노인에서 동맥경화지표와 단문형 국제신체활동설문지(IPAQ­SF)로 평가한 신체활동수준과의 관계)

  • Lee, Hyun-Ju;Gwak, Ji-Yeon;Jun, Ha-Yeon;Kim, Eun-Kyung
    • Korean Journal of Community Nutrition
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    • v.25 no.3
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    • pp.236-245
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    • 2020
  • Objectives: Cardiovascular disease is a major cause of death in the elderly in Korea. Increased arterial stiffness is linked to risk of cardiovascular disease and mortality. The purpose of this study was to investigate the relationship between arterial stiffness and physical activity in the elderly. Methods: A total of 209 older adults (110 men and 99 women) participated in this study. Arterial stiffness of subjects such as brachial-ankle pulse wave velocity (baPWV) and ankle brachial pressure index (ABI) was measured using a non-invasive vascular screening device (VP-1000 Plus, Omron, Kyoto, Japan). The interviewed Korean version of the international physical activity questionnaire short form (IPAQ-SF) was used to evaluate subject's physical activity level and classify subjects as active or inactive group based on the time spent doing moderate to vigorous physical activity (MVPA). Results: The mean age of total subjects was 75.3 ± 5.6 years. There was no significant difference in sex distribution between the active group (39.7%) and inactive group (60.3%). The baPWV (1,758.1 ± 375.2 cm/sec) of the active group was significantly lower than that (1,969.7 ± 372.3 cm/sec) of the inactive group (P < 0.05). There was a significant inverse association between time spent in MVPA and baPWV (r = -0.245, P < 0.01). Conclusions: This study suggests that physical activity programs for older adults are needed to prevent arteriosclerosis.

The fruit of Acanthopanax senticosus Harms improves arterial stiffness and blood pressure: a randomized, placebo-controlled trial

  • Oh, Eunkyoung;Kim, Youjin;Park, Soo-yeon;Lim, Yeni;Shin, Ji-yoon;Kim, Ji Yeon;Kim, Ji-Hyun;Rhee, Moo-Yong;Kwon, Oran
    • Nutrition Research and Practice
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    • v.14 no.4
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    • pp.322-333
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    • 2020
  • BACKGROUND/OBJECTIVES: Arterial stiffness and endothelial dysfunction are 2 of the independent predictors for cardiovascular disease, while Acanthopanax senticosus Harms (ASH) is a traditional medicinal plant that can improve cardiovascular health. This study aimed to investigate the efficacy of the fruit of ASH on vascular function in apparently healthy subjects. SUBJECTS/METHODS: A 12-week, randomized, double-blind, placebo-controlled design, consisting of healthy adults with at least 2 of the following 3 conditions: borderline high blood pressure (BP; 120 mmHg ≤ systolic BP ≤ 160 mmHg or 80 mmHg ≤ diastolic BP ≤ 100 mmHg), smoking (≥10 cigarettes/day), and borderline blood lipid levels (220 ≤ total cholesterol ≤ 240, 130 ≤ low density lipoprotein cholesterol ≤ 165, or 150 ≤ triglyceride ≤ 220 mg/dL). Randomly assigned 76 subjects who received a placebo or 2 doses of ASH fruit (low, 500 mg/day; high, 1,000 mg/day) completed the intervention. Brachial-ankle pulse wave velocity (baPWV), flow-mediated dilation, carotid intima-media thickness, and BP were measured both at baseline and following the 12-week intervention. Endothelial nitric oxide synthase (eNOS) phosphorylation was assessed by western blotting. RESULTS: Compared with the placebo group, the low-dose group showed more significant changes after the 12-week intervention period in terms of systolic BP (0.1 vs. -7.7 mmHg; P = 0.044), baPWV (31.3 vs. -98.7 cm/s; P = 0.007), and the ratio of phospho-eNOS/eNOS (0.8 vs. 1.22; P = 0.037). CONCLUSIONS: These results suggest that ASH fruit extract at 500 mg/day has the potential to improve BP and arterial stiffness via endothelial eNOS activation in healthy adults with smoking and the tendency of having elevated BP or blood lipid parameters.

A Study on the Correlation between the Second Derivative of Photoplethysmogram and Quality of Life using SF-36 Questionnaire in Women (광용적맥파와 SF-36을 이용한 여성의 삶의 질 관계 연구)

  • Jang, Young-Hun;Park, Young-Jae
    • The Journal of Korean Medicine
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    • v.41 no.2
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    • pp.34-42
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    • 2020
  • Background and Objectives: The purpose of this study was to examine the relationship between between one's quality of life (QoL) level and the arterial stiffness estimated by the second derivative of photoplethysmogram (SDPTG) for women patients. Methods: A retrospective chart review was performed on charts of 407 women patients (38.38±11.82 years) who visited Gangdong Kyung Hee Hospital between April 1st and September 30th, 2011. Vascular aging index (VAI, (b-c-d)/a), b/a, c/a, and d/a were considered as the arterial stiffness indexes, and the Korean version of the Short-Form 36 (SF-36) were completed to estimate one's physical and mental QoL. Results: Physical and mental components of the SF-36 in older group (50, 60, and 70 years-group) were lower than those in younger group (20 and 30 years-group). Large arterial stiffness-related b/a in older group was higher that in younger group, while small arterial stiffness-related d/a in older group was lower that in younger group. Physical and mental component scores of the SF-36 had the negative correlations with VAI and b/a (r; -0.153~-0.195), while had the positive correlations with c/a and d/a (r; 0.147~0.228). Conclusions: In conclusion, this study suggests that convenient and cost-effective SDPTG test may serve as an auxiliary tool to estimate one's physical and mental QoL.

Application of self-healing technique to fibre reinforced polymer wind turbine blade

  • Fifo, Omosola;Ryan, Kevin;Basu, Biswajit
    • Smart Structures and Systems
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    • v.16 no.4
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    • pp.593-606
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    • 2015
  • This paper presents a novel concept of healing some of the damages in wind turbine blades (WTBs) such as cracks and delamination. This is achieved through an inherent functioning autonomous repairing system. Such wind turbine blades have the benefit of reduced maintenance cost and increased operational period. Previous techniques of developing autonomous healing systems uses hollow glass fibres (HGFs) to deliver repairing fluids to damaged sites. HGFs have been reported with some limitations like, failure to fracture, which undermines their further usage. The self-healing technique described in this paper represents an advancement in the engineering of the delivery mechanism of a self-healing system. It is analogous to the HGF system but without the HGFs, which are replaced by multiple hollow channels created within the composite, inherently in the FRP matrix at fabrication. An in-house fabricated NACA 4412 WTB incorporating this array of network hollow channels was damaged in flexure and then autonomously repaired using the vascular channels. The blade was re-tested under flexure to ascertain the efficiency of the recovered mechanical properties.

Effects of Wear Training for Improving Vascular Compliance on Blood Pressures and Blood Lipid Profiles in Prehypertensive Subjects (온열요법으로서의 착의훈련이 고혈압 전단계자의 혈압 및 혈중 지질성분에 미치는 영향)

  • Yoo, Shin-Jung;Park, Joon-Hee
    • Korean Journal of Human Ecology
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    • v.21 no.1
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    • pp.141-149
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    • 2012
  • This study investigates the effects of wear training on blood pressure and blood lipid profiles. For the purpose of this research, 'wear training' refers to the alternating stimulation of temperature while using specific clothing under controlled situations ($18.8{\pm}0.2^{\circ}C$, $38{\pm}3%RH$). The participants alternated between two different garments producing a $1.5^{\circ}C$ difference in the innerest microclimate temperature over a period of 4 weeks. The experiments in this study were conducted in a comfortable environment after sufficient rest. The results were as follows. The systolic blood pressure and mean arterial pressure were lower in the post test than in the pre test (p<.05). The atherogenic index (AI) was also reduced and the LDL-C/HDL-C ratio increased (p<.05) in the post test. These results demonstrated that wear training positively affected improvement in vascular stiffness.

Effects of Uwhangchungsimwon on Arterial Stiffness (우황청심원이 정상인의 동맥경직도에 미치는 영향)

  • Rhee, Jun-woo;Moon, Sang-kwan;Park, Seong-uk;Jung, Woo-sang;Park, Jung-mee;Ko, Chang-nam;Cho, Ki-ho;Bae, Hyung-sup;Kim, Young-suk
    • The Journal of the Society of Stroke on Korean Medicine
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    • v.7 no.1
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    • pp.17-22
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    • 2006
  • Objectives : Uwhangchungsimwon (UC) is one of the famous herbal medicine frequently used for stroke, hypertension, and atherosclerosis, etc. Therefore, we intended to examine if UC could have therapeutic effect on arterial stiffness by assessing Cardio-Ankle Vascular lndex (CAVI). Methods : We enrolled 38 healthy male subjects (28±4.41 years old) and divided them into two groups (UC and control group). The UC group (N=22) were treated with 1 pill of UC and monitored by CAVI every hour for 6 hours. The control group(N=16) did not receive any medicine and were also monitored by CAVI the same manner as the UC group. In both group, we also assessed each subject's Yin-Yang pattern score by the diagnostic scoring system. In analysis, we compared the difference of CAVIs between the UC and the control group considering subject's Yin-Yang pattern. Results : There was no significant difference in the change of CAVI between the UC and the control group. After excluding Yang-pattern subjects in both group, however, we could observe that CAVI decreased significantly 5 hours after UC administration compared with the corresponding CAVI in the control group (P=0.025). In the repeated measure analysis, the between-subjects effect had statistical significance (P=0.035). Conclusion : According to these results, we suggest that UC have therapeutic effect on arterial stiffness especially after taking oriental medical diagnosis into consideration.

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Correlation between Arterial Stiffness and Physiological Parameters (동맥경화도와 생리학적 변수들 간의 상관관계)

  • Shin, Jae-Wook;Seok, Seong-Ja;Lee, Gil-Hyun;Choi, Seok-Cheol;Hyun, Kyung-Yae
    • The Korean Journal of Health Service Management
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    • v.7 no.3
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    • pp.71-82
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    • 2013
  • Arterial stiffness(AS) is an important pathologic state of vascular injury. This study was carried out to elucidate the effect of physiological variables on brachial-ankle pulse wave velocity(BAPWV), index of AS. Four hundred adults(volunteers) participated in this study. Body indices, biochemical, cardiac and inflammatory markers, and right(Rt)- and left(Lt)-BAPWV were measured. Body mass index(BMI), Rt- and Lt-BAPWV, glucose, triglyceride, alkaline phosphatase(ALP), gamma-glutamyl transferase(GGT), creatinine, uric acid, troponin-I(TNI), NT-proBNP and high sensitivity C-reactive protein(hs-CRP) levels were higher than the reference value of each variable. Rt- and Lt-BAPWV were directly correlated with age, body weight, BMI, glucose, ketone, aspartate aminotransferase, alanine aminotransferase, ALP, GGT, total cholesterol, low density lipoprotein, lipoprotein(a), apolipoprotein-B, blood urea nitrogen, heart rate, TNI, creatine kinase, CK-MB, lactic dehydrogenase, myoglobin, hs-CRP, lipase, reumatoid factor, fibrinogen and D-dimer (P<0.05, P<0.01, P<0.001 or P<0.000, respectively), but inversely associated with total bilirubin, uric acid, apolipoprotein-A1 and GFR (P<0.05). These observations suggest that a variety of physiological variables may influence BAPWV, resulting in increased risk or prevention of cardiovascular and/or cerebrovascular attacks. Therefore, physiological variables affecting BAPWV should be regularly controlled.