• 제목/요약/키워드: Vascular status

검색결과 195건 처리시간 0.026초

운동 의도에 따른 뇌파-근전도 신호 간 연결성 분석 (Connectivity Analysis Between EEG and EMG Signals by the Status of Movement Intention)

  • 김병남;김연희;김래현;권규현;장원석;유선국
    • 감성과학
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    • 제19권1호
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    • pp.31-38
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    • 2016
  • 뇌와 근육은 상의 하달식 구조로 상지 운동 수행 과정에서 뇌파와 근전도 신호의 변화와 함께 기능적 연결성이 발생한다. 본 논문에서는 사용자가 상지 운동을 수행하였을 때의 뇌파와 근전도 신호에 대해 코히어런스 방법을 적용하여 운동 의도 여부에 따른 뇌와 근육간의 연결성 차이를 규명하고자 한다. 상지 운동을 수행하는 과정에서 운동 피질 영역의 뇌파는 뮤 리듬(mu rhythm, 8~14 Hz)과 베타 리듬(beta rhythm, 15~30 Hz)에서 활성화 되며, 근전도 신호는 베타 리듬과 파이퍼 리듬(piper rhythm, 30~60 Hz)에서 활성화 된다. 뇌파와 근전도 신호간의 코히어런스 분석 결과 운동 의도를 포함한 능동 운동 수행 시 수동 운동을 수행하였을 때 보다 유의미한 차이로 높은 코히어런스 계수가 확인되었다. 이는 인지적 반응과 근육의 움직임 사이의 코히어런스 관계로 운동 의도가 포함된 상지 운동 수행 과정에서의 뇌와 근육간의 연결성을 해석할 수 있었다. 운동 의도에 따른 뇌-근육간의 코히어런스 특징을 이용한다면 재활기기 사용자의 운동 의도에 따라 피드백이 필요한 재활 훈련 시스템 설계에 도움이 될 수 있을 것으로 사료된다.

페루 도시 빈민지역 청소년의 비만에 따른 식생활 및 건강요인의 차이 (Differences in Dietary Life and Health related Factors According to Obesity in Poor Urban Peruvian Adolescents)

  • 정혜경;이해영;김진리;남은우
    • 대한지역사회영양학회지
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    • 제23권4호
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    • pp.302-318
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    • 2018
  • Objectives: This study examined the differences in dietary life and health related factors, such as drinking behavior, exercise and leisure activities, mental health, and subjective perception for oneself according to obesity in poor urban Peruvian adolescents. Methods: A total of 1,532 Peruvian adolescents were selected from six schools in poor regions using stratified random sampling. The subjects were classified into two groups based on their BMI: 'normal weight group (NW group=980)' or 'overweight and obese group (OWOB group=293)'. The differences in the general characteristics, dietary life, drinking behavior, physical activity and leisure, mental health and subjective perception of oneself in the two groups were compared. ${\chi}^2$ analysis and independent sample t-test were performed using the SPSS program ver. 24. Results: For the total and male students, the frequency of breakfast and dinner were significantly lower in the OWOB group than in the NW group (all p<0.001). For total and female students, the percentage of subjects who received nutrition education was significantly higher in the OWOB group than in the NW group (all p<0.05). For total students, the percentage of subject who exercised more than five days/week was lower in the OWOB group than in the NW group (p<0.05). For the total and female students, the subjective health status was worse in the OWOB group than in the NW group (all p<0.05). The subjective body image was significantly different between the OWOB group and NW group in the total, male and female subjects (all p<0.001). Conclusions: The frequency of meals and exercise, and the subjective perceptions of the health status and body image differed according to obesity in poor urban Peruvian adolescents. Therefore, a school-based intervention program focused on regular meal and exercise, and adequate subjective perceptions for health status and body image need to be developed to prevent adolescent obesity.

제주 성읍민속마을의 귀화식물 분포현황 및 관리방안 (A Study on the Distribution Status and Management Measures of Naturalized Plants Growing in Seongeup Folk Village, Jeju Island)

  • 노재현;오현경;한윤희;최영현;변무섭;김영숙;이원호
    • 한국전통조경학회지
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    • 제32권1호
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    • pp.107-119
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    • 2014
  • 제주시 성읍민속마을을 대상으로 관속식물상 및 귀화식물의 현황을 조사하고, 여타 민속마을과 제주도 전역에 분포하는 귀화식물의 분포양상 및 발생특성과 비교 고찰함으로써 이곳의 귀화식물의 관리방안을 모색할 목적으로 시도된 본 연구의 결론은 다음과 같다. 성읍민속마을의 관속식물상은 93과 260속 298종 44변종 12품종으로 총 354분류군이 확인되었으며, 이 중 귀화식물은 22과 46속 53종 2변종의 총 55분류군으로 이는 제주도 전역에서 확인된 총 254분류군의 21.7%에 해당된다. 이에 따른 성읍민속마을의 귀화율은 15.5%로서 이는 경북 안동의 하회마을, 경주의 양동마을, 성주의 한개마을, 강원 고성의 왕곡마을 그리고 충남 아산의 외암마을에 비해 월등히 높은 수치였다. 마을내 발생한 귀화식물 중 분포지가 제주도에 한정되어 있는 것은 양장구채, 국화잎아욱, 애기달맞이꽃, 긴잎달맞이꽃, 솔잎미나리, 자주풀솜나물, 선풀솜나물, 큰참새피, 등심붓꽃 등 9분류군으로, 귀화식물의 이입 관문이자 선구 발생지로서의 특성을 살린 적절한 관리전략이 필요한 것으로 판단된다. 한편 본 연구를 통해 제주도 기준목록에는 포함되지 않았던 까락빕새귀 리, 삼, 눈개불알풀 등 3분류군이 성읍민속마을에서 처음으로 확인되었다. 단위문화재 정원내 발생한 귀화식물은 총 20분류군으로 이 중 유럽점나도나물의 출현율이 62.5%로 가장 높았으며, 미국자리공 선개불알풀 망초 방가지똥 큰방가지똥(37.5%)도 비교적 높게 나타났는데 이는 제주도뿐만 아니라 대부분의 민속마을과 레크레이션공간의 공통된 특성으로 보인다. 한편 경관관리적 취급이 요망되는 식물군락은 유채를 비롯하여 귀화식물인 코스모스, 토끼풀, 잔개자리, 긴잎달맞이꽃, 애기달맞이꽃, 서양벌노랑이, 호밀풀, 양장구채, 서양금혼초, 미국질경이, 큰이삭풀, 유럽점나도 나물 등으로 분석되었다. 성읍민속마을의 단기적 귀화식물 관리방안으로는 경관농업적 차원에서 식재되고 있는 코스모스와 유채의 임내 침투 현황과 개화 후 활용 방안의 모색이 필요하다. 환경부가 지정한 생태계교란야생식물인 돼지풀과 서양금혼초는 우선적으로 제거하고, 재발에 대비한 추가 발생과 확산과 팽창을 염두에 둔 모니터링의 실시를 제안한다. 특히 서양금혼초는 서식밀도 파악 및 제근 등 물리적인 방제방안이 강구되어야 할 것이다. 또한 시각적으로 녹시율이 높은 정의읍성 외벽에 자생하는 방가지똥, 약모밀, 주홍서나물, 개망초, 자주광대나물의 제거가 시급하다. 이와 함께 폐 공가에 귀화식물의 분포와 우점도가 높음에 따라 공가에 대한 보존관리 및 민박 활용방안 등을 강구해야 할 것이다.

Vascular Endothelial Growth Factor (VEGF) Gene Polymorphisms and Breast Cancer Risk in a Chinese Population

  • Luo, Ting;Chen, Long;He, Ping;Hu, Qian-Cheng;Zhong, Xiao-Rong;Sun, Yu;Yang, Yuan-Fu;Tian, Ting-Lun;Zheng, Hong
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권4호
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    • pp.2433-2437
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    • 2013
  • Vascular endothelial growth factor (VEGF) is a potent regulator of angiogenesis and thereby involved in the development and progression of solid tumours. Associations between three VEGF gene polymorphisms (-634 G/C, +936 C/T, and +1612 G/A) and breast cancer risk have been extensively studied, but the currently available results are inconclusive. Our aim was to investigate associations between three VEGF gene polymorphisms and breast cancer risk in Chinese Han patients. We performed a hospital-based case-control study including 680 female incident breast cancer patients and 680 female age-matched healthy control subjects. Polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) analysis was performed to detect the three VEGF gene polymorphisms. We observed that women carriers of +936 TT genotypes [odds ratio (OR) =0.46, 95% confidence interval (CI) = 0.28, 0.76; P=0.002] or 936 T-allele (OR=0.81, 95% CI= 0.68, 0.98; P=0.03) had a protective effect concerning the disease. Our study suggested that the +1612G/A polymorphism was unlikely to be associated with breast cancer risk. The -634CC genotype was significantly associated with high tumor aggressiveness [large tumor size (OR=2.63, 95% CI=1.15, 6.02; P=0.02) and high histologic grade (OR=1.47, 95% CI= 1.06, 2.03; P=0.02)]. The genotypes were not related with other tumor characteristics such as regional or distant metastasis, stage at diagnosis, or estrogen or progesterone receptor status. Our study revealed that the VEGF -634 G/C and +936 C/T gene polymorphisms may be associated with breast cancer in Chinese Han patients.

경남 합천군의 관속식물 분포와 자원특성에 관한 연구 - 오도산, 황매산, 대암산, 무월봉을 중심으로 - (Distribution of Vascular Plants and Plant Resources Characteristics in Hapcheon-gun, Gyeongsangnamdo Province - Mt. Odo, Mt. Hwangmae, Mt. Daeam, and Muweol Peak -)

  • 한종원;김현준;강신호;양선규;박정미;장창기
    • 한국환경생태학회지
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    • 제24권4호
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    • pp.406-425
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    • 2010
  • 2009년 3월부터 10월까지 경상남도 합천군일대의 자원식물분포조사를 수행하였다. 본 조사를 통해 확인된 조사지역내의 소산 관속식물은 82과 292속 427종 4아종 49변종 9품종으로 총 489분류군으로 확인되었다. 조사 지역에서 분포하고 있는 식물의 자원 유용도를 분석한 결과, 식용자원식물이 187분류군, 섬유용 자원식물이 9분류군, 약용 자원식물이 137분류군, 관상용 자원식물이 52분류군, 초지 자원식물이 126분류군, 공업원료자원이 2분류군, 염료용 자원식물이 112분류군, 목재용 자원식물이 16분류군, 용도가 밝혀지지 않은 식물이 134분류군로 구분되었다 특기할만한 식물로는 한국 특산 관속식물이 총 18분류군, 환경부지정 특정식물종이 33분류군, 희귀식물은 2분류군으로 각각 조사되었고, 귀화식물은 44분류군으로서 전체분류군의 약 8.9%를 차지하였다. 한편 조사지역의 식생은 비교적 양호한 편이었으나, 레저시설이 형성되거나, 중계소, 사찰 등으로 인한 임도와, 저지대의 많은 농경지로 인해, 귀화식물의 분포가 빠르게 확산될 우려가 크므로 이에 따른 적절한 조치가 필요할 것으로 판단된다.

복강경 담낭절제술 시 공기배증 전에 주입한 복강 내 lidocaine의 공기배증 후 혈압상승 완화효과 (Attenuation of pneumoperitoneum-induced hypertension by intra-peritoneal lidocaine before pneumoperitoneum in laparoscopic cholecystectomy)

  • 송선옥;이혜미;윤성수;유화림;심수영;김흥대
    • Journal of Yeungnam Medical Science
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    • 제33권2호
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    • pp.90-97
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    • 2016
  • Background: We have previously found that intra-peritoneal lidocaine instillation before pneumoperitoneum attenuates pneumoperitoneum-induced hypertension. Whether this procedure alters patient's hemodynamic status during operation should be determined for clinical application. This study elucidated the possible mechanism of the attenuation of the pneumoperitoneum-induced hypertension by intra-peritoneal lidocaine before pneumoperitoneum. Methods: Thirty-four patients underwent laparoscopic cholecystectomy (LC) were randomly allocated into two groups. After induction of general anesthesia, 200 mL of 0.2% lidocaine (lidocaine group, n=17), or normal saline (control group, n=17) were sub-diaphragmatically instilled 10 minutes before pneumoperitoneum. The changes in systolic blood pressure, heart rate, central venous pressure, stroke volume, cardiac output, and systemic vascular resistance were compared between the groups. The number of analgesics used during post-operative 24 h was compared. Results: Systolic blood pressure was elevated during pneumoperitoneum in both groups (p<0.01), but the degree of elevation was significantly reduced in the lidocaine group than in the control (p<0.01). However, stroke volume and cardiac output were decreased and systemic vascular resistance was increased after induction of pneumoperitoneum (p<0.05) without statistical difference between two groups. The number of analgesics used was significantly reduced in the lidocaine group (p<0.01). Conclusion: These data suggest that intra-peritoneal lidocaine before pneumoperitoneum does not alter patient's hemodynamics, and attenuation of pneumoperitoneum-induced hypertension may be the consequence of reduced intra-abdominal pain rather than the decrease of cardiac output during pneumoperitoneum. Therefore, intra-peritoneal lidocaine instillation before pneumoperitoneum is a useful method to manage an intraoperative pneumoperitoneum-induced hypertension and to control postoperative pain without severe detrimental hemodynamic effects.

Descending Aorta Blood Flow Characteristics before the Development of Necrotizing Enterocolitis in Preterm Neonates

  • Kim, Kyung Min;Kim, Hyo Sup;Yoon, Ji Hong;Lee, Eun-Jung;Yum, Sook Kyung;Moon, Cheong-Jun;Youn, Young-Ah;Kwun, Yoo Jin;Lee, Jae Young;Sung, In Kyung
    • Neonatal Medicine
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    • 제25권2호
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    • pp.78-84
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    • 2018
  • Purpose: To investigate the hemodynamic risk factors for necrotizing enterocolitis (NEC), we analyzed the characteristics of descending aorta (DA) blood flow in preterm neonates, who later developed NEC. Methods: This was an observational case-control study on 53 preterm neonates at a tertiary referral center. Clinical and echocardiographic data were collected from 23 preterm neonates with NEC (NEC group), and compared with those of 30 preterm neonates without NEC (control group). Echocardiography was done at a median (interquartile range) of 5 (3-9) days after birth and 2 (1-2.5) days before the diagnosis of NEC. Results: Basic clinical characteristics including gestational age, birth weight, Apgar score, breast feeding status, use of umbilical catheters, and mode of invasive ventilator care were similar between the groups. Compared with the control group, the lowest diastolic velocity of DA was significantly decreased, whereas the diastolic reverse flow and the ratio of diastolic reverse to systolic forward flows were significantly increased in the NEC group. In addition, the resistive index (RI) of DA was significantly increased in the NEC group and showed a positive association with the development of NEC. Multivariate logistic regression analysis showed that increasing RI of DA was an independent risk factor for the development of NEC (P=0.008). Conclusion: Significant changes in DA flow characteristics including decreased diastolic velocity and increased diastolic reverse flow along with increased peripheral vascular resistance were observed before the development of NEC in preterm neonates. These findings may help clinicians stratify in advance neonates at a risk of developing NEC and may help improve outcomes in these neonates.

치매 환자(患者) 84례(例)에 대한 유형별(類型別) 임상고찰(臨床考察) (The Clinical Analysis on 84 Cases of Dementia)

  • 전상윤;강화정;김윤완;홍석
    • 대한한방내과학회지
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    • 제21권2호
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    • pp.193-201
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    • 2000
  • Objective : In western medicine, many medication therapies and non-medication therapies have been treated for dementia. But these methods did no more than symptomatic therapies, not basic treatment, which just can better subordinate symptoms. In fact, care or control became the very point of treatment of dementia. So, to try to find oriental medical treatments for Dementia, a clinical analysis was carried out for 84 patients who were diagnosed as Dementia through MMSE-K and treated in Dong-shin Oriental Medicine Kwangju Hospital and Karitaas Sanatorium from 10. Jan. 1998 to 20. May. 2000. Methods : Regardless of patterns of Dementia, the basic treatment(本治) is to supplement encephalon deficiency(腦髓不足). And the external treatment(標治) must be accompanied by through diagnosis according to symptoms(辨證). All patients were given Yukmi-jihwanghwan gami and acupuncture treatment. Results : Dementia of cerebral vascular type shows a high distribution(51 patients, 60.7%). Women also are distributed more widely(62명, 73.8%). In Age distribition, 70-79 years-32 patients(38.1%), over 80 years-21 patients(25%), 60-69 years-17 patients(20.2%), 50-59 years-13 patients(15.5%) and under 49 years-1 patient(1.2%). From this, Dementia occurs well over 60 years and the rate of occurrence of Dementia is high as people grow older. In past history of people with Dementia, hypertension is associated much(50 patients, 64.1%). Distribution of mental state by MMSE-K examination declined in orientaion, mathmatical faculty, memory faculty and composition faculty. In therapeutic effect by treatment duration, 14 patients(93.3%) out of 15 in sanatorium show a significant effect. And 52 patients(75.4%) out of 69 in the hospital show the same result. Especially, 11 patients with Alzheimer type in sanatorium showed an good effect when treated over 4 months. 40 patients(83.3%) with cerebral vascular type out of 48 in the hospital showed the stage of betterment. Conclusions : The basic treatment(本治) for Dementia is to supplement encephalon deficiency(腦髓不足). For promoting encephalon through supplementing kindney(補腎健腦), All patients were given Yukmi-jihwanghwan gami. And the external treatment(標治) through diagnosis according to symptoms(辨證) were be accompanied by. The result is quite effective. We consider there must be more research based on this study.

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The Blood Neutrophil-to-lymphocyte Ratio Predicts Survival in Patients with Advanced Hepatocellular Carcinoma Receiving Sorafenib

  • Zheng, You-Bing;Zhao, Wei;Liu, Bing;Lu, Li-Gong;He, Xu;Huang, Jian-Wen;Li, Yong;Hu, Bao-Shan
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권9호
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    • pp.5527-5531
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    • 2013
  • Background and Aim: Increasing evidence correlates the presence of systemic inflammation with poor survival in patients with hepatocellular carcinoma (HCC). The aim of this study was to investigate the prognostic significance of the blood neutrophil-to-lymphocyte ratio (NLR) in patients with advanced HCC who received sorafenib monotherapy. Methods: A total of sixty-five patients with advanced HCC, not eligible for locoregional therapy, treated with sorafenib were enrolled. Potential prognostic factors such as age, gender, tumoral characteristics, performance status and NLR were analyzed. Results: Median OS and TTP for the entire cohort were 10.0 months (95%CI, 7.6-12.3 months) and 4.5 months (95% CI, 4.0-4.9 months). The mean NLR at baseline was 2.89. The median OS of patients with a high NLR (>4) was 6.5 months (95%CI, 5.2-7.7 months) compared with 12.5 months (95%CI, 9.9-15.0) for patients with a normal NLR (${\leq}4$) (P=0.01). Age ${\leq}65$, NLR>4, extrahepatic metastases and vascular invasion were all predictors of poorer overall survival. Multivariate analysis showed that NLR > 4, vascular invasion and extrahepatic metastases were independent predictors of poorer overall survival. The median TTP of patients with a high NLR was 2.5 months (95%CI, 1.4-3.6 months) compared with 4.5 months (95%CI, 3.9-5.1 months) for patients with a normal NLR (P=0.012). Conclusions: High baseline NLR was associated with worse OS and TTP for patients with advanced HCC treated with sorafenib.

덕적도(인천)의 관속식물상 조사 연구 (The Study for Flora of Vascular Plants of Deokjeokdo (Incheon))

  • 백은호;문애라;박정미;장창기
    • 환경생물
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    • 제28권3호
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    • pp.158-171
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    • 2010
  • 비교적 크기가 크고 남방계인자들이 간헐적으로 보고 된 덕적도 일대에 대하여 자연자원의 분포를 규명하고, 환경 및 기후변화 등의 기초 자료를 제공하기 위하여 관속식물에 대한 분포조사를 2007년 9월부터 2008년 9월까지 35회에 걸쳐 수행하였다. 본 조사를 통해 확인된 조사지역 내의 소산 관속식물은 108과 320속 480종 2아종 45변종 8품종의 535분류군으로 확인되었다. 관속식물 중에서 국화과 식물이 가장 많은 비율을 차지하고 있었고 벼과, 콩과, 장미과의 순이었다. 특정식물로는 한국 특산 관속식물 4분류군, 산림청 지정 희귀 및 멸종위기식물 6분류군, 환경부지정 특정식물종 55분류군이 각각 조사되었고, 반면에 귀화식물은 50분류군이 조사되어 전체식물상의 약 17.9%를 차지하였다. 조사지역의 식생은 일부 지역에서 인간 활동에 의해 교란되어 있었으나 대체로 양호한 상태이고 일부 지역은 특이할 만한 식물들도 발견되어 체계적인 보호가 요구되어졌다. 인간 간섭이 심할 것으로 판단되는 저지대의 대부분 지역에서 귀화식물의 점유율이 아주 높았고, 차후로 귀화식물의 분포가 빠르게 확산될 것이 예상되어 생태계의 교란이 우려되어 지므로 이에 대한 대책이 수립되어야 할 것으 로 보아진다.