• Journal of Korean Society for Atmospheric Environment
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• v.16 no.4
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• pp.327-338
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• 2000

complexity in atmospheric environment coupled with shoreline and complex terrain often causes local variations of meteorology that are distinct from those representative over larger surrounding area, These kinds of local variations are less significant in usual long-term environmental impact analyses dealing with continuous plume. The variations could however be crucial in predicting dispersion of toxic substance released in a relatively small area for a short duration. In the present paper the effects of spatial and temporal resolution of diagnostic wind field on the dispersion of the released substance are investigated by using a puff model. A hypothetical release scenario assumes that a substance is released from a location in the Yochon Industrial Estate and passively dispersed within a few-kilometer distance for an hour. The results show that diagnostic analysis could resolve more spatial variations to some extent by employing smaller grid size. The peak concentrations and puff trajectories obtained from spatially -and/or tmeporally -varing diagnostic wind field are found appreciably different from those obtained from uniform wind field. Attention to high-resolution wind field in the both spatial and temporal spaces is called in the consequence analysis of toxic substance release.

• Structural Engineering and Mechanics
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• v.44 no.5
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• pp.663-680
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• 2012

Previous major earthquakes revealed that most damage of the buried segmented pipelines occurs at the joints of the pipelines. It has been proven that the differential motions between the pipe segments are one of the primary reasons that results in the damage (Zerva et al. 1986, O'Roueke and Liu 1999). This paper studies the combined influences of ground motion spatial variations and local soil conditions on the seismic responses of buried segmented pipelines. The heterogeneous soil deposits surrounding the pipelines are assumed resting on an elastic half-space (base rock). The spatially varying base rock motions are modelled by the filtered Tajimi-Kanai power spectral density function and an empirical coherency loss function. Local site amplification effect is derived based on the one-dimensional wave propagation theory by assuming the base rock motions consist of out-of-plane SH wave or combined in-plane P and SV waves propagating into the site with an assumed incident angle. The differential axial and lateral displacements between the pipeline segments are stochastically formulated in the frequency domain. The influences of ground motion spatial variations, local soil conditions, wave incident angle and stiffness of the joint are investigated in detail. Numerical results show that ground motion spatial variations and local soil conditions can significantly influence the differential displacements between the pipeline segments.

• Journal of Pharmaceutical Investigation
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• v.36 no.6
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• pp.421-435
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• 2006

The objective of this report is to introduce the European Union's variation rules governing medicinal products that are subject to post-approval changes. The EMEA outlines a variety of changes occurring to approved medicinal products. It also recommends a marketing authorisation holder to follow specific post-approval applications in various situations. For instance, the Commission Regulation(EC) No. 1085/2003 explains variation types and suggests post-authorisation procedures with which an applicant should comply. In all cases of minor and major variations the applicant has to investigate and validate whether or not the intended changes would have impact on the safety, efficacy and quality of a drug product. The applicant should then submit to the EMEA a variation application with adequate documentation in support of the notified changes. This procedure is implemented to ensure that changes to the approved medicinal product do not cause my public health concerns. In fact, the post-authorisation guidance categorizes post-approval changes into type IA/IB variations, type II variations, and extension applications. Such classifications determine administrative procedures to be followed in an efficient manner. Based on the type of a variation, the regulatory agency opts to reduce or extend the evaluation time-frame. The thrust of the EU's post-authorisation guidance is introduced in text with appropriate explanation. All these information will be likely to be helpful in updating a Korean regulatory guidance that could better deal with post-approval changes to generic drugs available in the market.

• The Korean Journal of Malacology
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• v.27 no.4
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• pp.345-351
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• 2011

Comparison of different morphological characteristics of bivalves is very useful for distinguishing species. Therefore, this study used a morphometric approach to document patterns of phenotypic change through the specimens of family Pinnidae inhabiting the bottom sediments at the coasts of An Thoi Archipelago (south-eastern Gulf of Thailand), in that way excluding intraspecific variations among different populations along a wide geographical range. It was revealed that individuals determined as Pinna trigonium separated from specimens of Pinna nigra and Atrina vexillum at high level, but P. nigra and A. vexillum were the single species A. vexillum, as it is assumed now. Also, it was found that both groups of P. trigonium individuals and A. vexillum specimens divided into tree subgroups unified the specimens with the similar morphometric parameters: small, medium and large within the populations, though there were no evident divisions into subgroups in the size distributions of the populations. In addition to the interspecific morphological variations, the species also showed significant intraspecific morphological variations even in the same population. Most probable reason for the appearance of the intraspecific morphological variations and division of all specimens into size-specific subgroups in the population is the fact that the growth of Pinnidae bivalves is not isometric.

• Journal of Korean Society for Atmospheric Environment
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• v.18 no.4
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• pp.253-264
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• 2002

Surface ozone concentrations measured at 40 monitoring sites in three major cities (Seoul, Busan, and Daegu) of Korea during 1993~2000 were analyzed to understand the characteristics of temporal and spatial distributions. Trends were analyzed for annual mean, 95th percentiles of daily 8-hour maximum and days exceeding 8-h ozone standard of 60 ppb. Three indicators exhibited increasing trends (+0.75 ppb yr$^{-1}$ , +2.20 ppb yr$_{-1}$ , and +5.35 days yr$_{-1}$ on average) throughout the study period at all cities. Diurnal and seasonal variations were the largest in Seoul followed by Daegue and Busan, due to the high photochemical production and titration of ozone (Seoul), strong wind and constant supply of background ozone from the ocean (Busan). In the urban centers and industrial areas at all cities, scavenging of ozone by NO reduces the daily 8-hour maximum ozone by 10 ppb on average. High concentrations of ozone have frequently occurred in downwind eastern (Seoul and Daegu) or northern (Busan) sides of the territory. In particular, the coastal area of Busan had relatively high ozone level due to the local sea land breeze circulation. The results indicated that the temporal and spatial variations of ozone concentration were non -uniform and were closely related to the local environments; emission levels, climates, and geographic locations.

• Journal of Korea Foresty Energy
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• v.18 no.1
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• pp.1-5
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• 1999

Variations in the wood quality were analyzed to utilize Korean pine (Pinus koraiensis S. et Z.) efficiently and to develop suitable use, depending on the stem location. Variations in the tracheid length and width, microfibril angle, compression strength were measured at the heights of 0.3, 1.3, 2.3, and 5.3m in the longitudinal direction of the 20m pine and they were analyzed by Duncan`s multiple range test. Variations in the tracheid length, width and compression strength did not show significant difference, whereas those in the microfibril angle showed significant difference. However, the microfibril angle did not vary with the height of trees, showing inconsistent pattern in change.

• Journal of The Korean Astronomical Society
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• v.53 no.3
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• pp.69-75
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• 2020

We study the photometric phase curves for the planets of our solar system which can be considered as a prototypical non-compact planetary system. We focus on modeling the small variations caused by three effects: reflection, ellipsoidal, and Doppler beaming. Theoretical predictions for these photometric variations are proposed, considering a hypothetical external observer. Unlike similar studies of multi-planetary systems, the physical and geometrical parameters for each planet of the solar system are well-known. Therefore, we can accurately evaluate the relationships that shape the planetary light curves for a fictitious external observer. Our results suggest that, for all planets, the ellipsoidal effect is very weak while the Doppler beaming effect (DBE) is, in general, dominant. In fact, the DBE seems to be the principal cause of variations of the light curves for the planets of the solar system. However, for Mercury and Venus the Doppler beaming and reflection effects have similar amplitudes. The phase curves obtained for the planets of the solar system show new interesting features of interest for the study of other non-compact planetary systems.

• Ocean and Polar Research
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• v.31 no.2
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• pp.219-229
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• 2009

In order to establish annual variations in the marine ecosystem of the East China Sea, suspended solids (SSs) and particulate organic carbon (POC) were extensively investigated in the northern part of the East China Sea from August 2003 to April 2008. Surface SS concentrations showed large spatial variations in spring and fall, but not in summer. Surface SS concentrations in spring were lower than those in summer and fall. In summer, SSs discharged from Changjiang were mostly deposited in the coastal areas and did not reach our study area which was located about 260 km from the river mouth. High SS concentrations were observed near the bottom, which resulted from resuspension of bottom sediments by the bottom currents. Surface POC concentrations did not exhibited large seasonal variations. Phytoplankton biomass was a main factor controlling surface POC concentrations. POC/chlorophyll ratios showed large seasonal variations, with maximum numbers in summer. POC/PON ratios were higher in summer than the Redefied ratio (6.6), while they were lower in spring and fall. In summer, higher POC/chlorophyll and POC/PON ratios were probably attributed to the high phytoplankton mortality caused by nutrient depletion in surface waters.

• Ocean Systems Engineering
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• v.7 no.1
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• pp.21-38
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• 2017

In real sea environments, excessive dynamic axial tension variations can be exerted on the top-tensioned risers (TTRs) and lead to structural integrity issues. The traditional riser-tension-variation analysis, however, by using parametric formulation is only conditionally valid under certain strict limits and potentially underestimates the total magnitudes of tension variations. This phenomenon is especially important for the long stroke tensioner in dry-tree semisubmersible with larger global heave motion and longer stroke. In this paper, the hydro-pneumatic tensioner (HPT) is modeled in detailed component-level which includes a set of hydraulic and pneumatic components. The viscous fluid frictional effect in the HPT is considered. The main objectives are (i) to develop a detailed tension variation model of the HPT; (ii) to identify the deviations between the conventional parametric formulation and component-level formulation; (iii) to numerically analyze the tension variation of long stroke tensioner in a dry-tree semisubmersible (DTS). The results demonstrate the necessity of component-level formulation for long stroke tensioner in the development of DTS.

• Journal of the Korean Chemical Society
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• v.6 no.2
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• pp.176-197
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• 1962

Seasonal variations of chemical constituents of estuarine water at a definite station of the tidal flat in Guang Yang inlet have been determined for two days a month. The range and mean of the annual variations are as follows:Tidal variations through a year are as follows:1. Although the tidal value of pH is almost constant during one tidal cycle, it raises abruptly 0.1-0.2 intervals of pH value during the first period of flood.2. The lower values of chlorinity, magnesium and calcium contents have been determined the nearer the slack after ebb, and slightly higher during the first period of flood tide than the last of ebb. The tidal change of calcium contents is more remarkable than of magnesium.3. The higher per cent saturation values of dissolved oxygen, sometimes higher than 100 per cent, re determined the nearer the slack after ebb.4. The total nitrogen contents, relatively poor, varies accidentally during one tidal cycle, whereas phosphate-P and silicate-Si are rich at the slack after ebb and increase proportionally to the mixing percentage of fresh water. The average values, 52.2 and 18.5 of Si/P and N/P are greater than of the normal.5. The acid soluble iron contents, lower in winter than in summer, is also varies accidentally during one tidal cycle and the magnitude of the variation is large.6. The chemical composition considered from the value of Ca/Cl or Mg/Cl of estuarine water varies according to the chlorinity even at the high chlorinity of 18-19%.