• Title/Summary/Keyword: Variance of Analysis

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Formulation Optimization of the Tablet Prepared with Solid Dispersion of Biphenyl Dimethyl Dicarboxylate with Poloxamer (비페닐 디메칠 디카르복실레이트 고체분산체 정제 처방의 최적화)

  • Lee, Jang-Won;Park, Eun-Seok;Chi, Sang-Cheol
    • Journal of Pharmaceutical Investigation
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    • v.28 no.4
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    • pp.267-274
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    • 1998
  • Biphenyl dimethyl dicarboxylate (DDB) has been used for the treatment of acute and chronic hepatitis. However, its poor solubility in water, $2.5\;{\mu}g/ml$, caused low bioavailability of the drug after its oral administration. In order to increase the dissolution of DDB in gastrointestinal tracts, consequently to increase the bioavailability of the drug, DDB tablet was prepared with solid dispersion of DDB with poloxamer 338 or 407 using a direct compression method. To improve the flowability of the solid dispersion, Aerosil was used as an adsorbent. The effect of formulation variables (poloxamer and Aerosil contents) on the dissolution rate of DDB from tablets was investigated using an analysis of variance. The dissolution rate of DDB from tablets was evaluated with KP II (paddle) method. The dissolution patterns of the drug from the tablet prepared with poloxamer 407 were affected significantly by the contents of poloxamers and Aerosil over the range employed, but those of the drug from the tablet prepared with poloxamer 338 were not. The optimum formulation of the DDB tablet, showed the same dissolution pattern as that of the reference, was obtained after polynomial equations of drug dissolution profiles for each formula were fitted to contour plots. The optimum formulation ratios of DDB:poloxamer 407:Aerosil were 1:2.5:2.5 and 1:5:5.

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Optimization of photo-catalytic degradation of oil refinery wastewater using Box-Behnken design

  • Tetteh, Emmanuel Kweinor;Naidoo, Dushen Bisetty;Rathilal, Sudesh
    • Environmental Engineering Research
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    • v.24 no.4
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    • pp.711-717
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    • 2019
  • The application of advanced oxidation for the treatment of oil refinery wastewater under UV radiation by using nanoparticles of titanium dioxide was investigated. Synthetic wastewater prepared from phenol crystals; Power Glide SAE40 motor vehicle oil and water was used. Response surface methodology (RSM) based on the Box-Behnken design was employed to design the experimental runs, optimize and study the interaction effects of the operating parameters including catalyst concentration, run time and airflow rate to maximize the degradation of oil (SOG) and phenol. The analysis of variance and the response models developed were used to evaluate the data obtained at a 95% confidence level. The use of the RSM demonstrated the graphical relationship that exists between individual factors and their interactive effects on the response, as compared to the one factor at time approach. The obtained optimum conditions of photocatalytic degradation are the catalyst concentration of 2 g/L, the run time of 30 min and the airflow rate of 1.04 L/min. Under the optimum conditions, a 68% desirability performance was obtained, representing 81% and 66% of SOG and phenol degradability, respectively. Thus, the hydrocarbon oils were readily degradable, while the phenols were more resistant to photocatalytic degradation.

A Study on Homemaker's Consciousness to the Management of Apartment house (아파트 관리에 관한 주부의 의식조사연구)

  • 임정빈;안영애
    • Journal of Families and Better Life
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    • v.1 no.2
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    • pp.21-42
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    • 1983
  • This paper aims to present basic data in order to improve the management of apartment house through grasping homemaker's concern about the management of apartment house satisfaction and dissatisfaction with it, and , furthermore, to suggest the best way to enjoy pleasent life of apartment house. The date collected through the questionnaire were analyzed, using the analysis of variance, chi square, and Pearson product moment correlation coefficient. The conclusion of this are as follows: 1) The homemakers are concerned with the management of apartment house, but they seem to dissatisfy with it. 2)The apartment house of the management of self-government contains may factors of dissatisfaction than of commission, expecially in the management of inside facilities. 3)When homemakers in the apartment house of the management of the self-government are very concerned with the management of the area, they are satisfied with. For the management of it's facilities, however, the more they show concerns with it, the less they satisfy with it. But for the case of the management of commission, they are interested in the management of inhabitants and satisfied with it. 4) The homemakers in the apartment house of the self-government are satisfied with the management of the whole if they gave friendship and trust on the manger, and get accustomed the life of the apartment house and enjoy it. While those who have friendship and trust on the manger in the management of commission have concern and satisfaction with the management.

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Factors Associated with the Practice of Traditional Prenatal Education (Taegyo) among Pregnant Korean Women

  • Kim, Young-Hee
    • Women's Health Nursing
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    • v.17 no.5
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    • pp.491-498
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    • 2011
  • Purpose: Recently as couples have only one or two children, they concern about their children's optimal health. Furthermore, as the basic principles of Korean traditional prenatal education (Taegyo) are supported by scientific evidence, and as increasing numbers of pregnant women are recognizing Taegyo refresh, the practice of Taegyo is growing. The purpose of this study was to identify the factors associated with the practice of Taegyo among pregnant Korean women. Methods: This was a cross-sectional, survey study of 228 pregnant women recruited at a health center in South Korea using a convenience sampling method. The instruments included the perception of Taegyo scale, the spouse's support scale, the self-confidence for infant care scale, and the practice of Taegyo scale. The data were analyzed using descriptive statistics and multiple regression analyses. Results: The results of the stepwise multiple regression analysis indicated that the following factors accounted for 26.5% of the variance in the practice of Taegyo: the perception of Taegyo, family income. Conclusion: Consequently, this result showed that the pregnant women were influenced by family income, spouses' support as requisite factors, and also they developed the level of self-confidence for infant care and the perception of Taegyo as self-care agency for the practice of Taegyo. The present study findings will add to the accumulated knowledge of health care professionals about the cultural factors involved in the practice of Taegyo and the traditional cultural beliefs and culture-specific health promoting behaviors of ethnic minority pregnant women to provide culturally competent care for them.

Impact of Topsoil Stockpiling Methods on the Viability of Seed Banks

  • Yi, Myung-Hoon
    • Journal of Environmental Science International
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    • v.27 no.10
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    • pp.907-923
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    • 2018
  • The aim of this study was to determine the appropriate stockpiling methods for revegetation by comparing the germination status of seed banks before and after preservation for 2 years. Soil temperature in stockpiled topsoil was higher in open treatment and at 1.5 m, whereas soil water content was maintained at lower levels (14.06-19.08%), than those in the control group. The seed banks in stockpiled topsoil had 48 species and 1,559 individuals, among which perennials showed the highest number in terms of life forms, whereas Compositae and Gramineae were dominant in terms of families. Based on seed bank type, persistent seed banks had the highest number of species, while transient seed banks had the highest number of individuals. By stockpiling period, the number of species in the seed bank started to increase after 24 months, while the number of individuals began increasing after 12 months and exceeded that of the control group after 24 months. Regarding the treatment of stockpiling methods, the number of species and individuals in open treatment were closer to those of the control group. When analyzed by height, the number of species and individuals were higher at 0 m, but still lower than those of the control group. A multivariate analysis of variance (MANOVA ) showed that the optimal combination was obtained in open treatment and the number of individuals increased with the lengthening of the stockpiling period.

Home Nursing and Quality of Life in Parents of Children with Atopic Dermatitis (아토피피부염 환아 부모의 가정관리와 삶의 질)

  • Kwon, In-Soo;Seo, Yeong-Mi
    • Child Health Nursing Research
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    • v.15 no.4
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    • pp.401-408
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    • 2009
  • Purpose: This study was done to assess the home nursing and quality of life of parents caring for preschool children with atopic dermatitis and to identify the factors which influence quality of life. Methods: Participants in the study were 149 parents of preschool children with atopic dermatitis attending a kindergarten and a nursery school in S city. Parent completed a set of questionnaires (assessing demographic factors, home nursing, quality of life). Descriptive analysis, t-test, ANOVA and multiple regression were used to analyze the data. Results: The mean score for home nursing was $3.06{\pm}0.38$ and for quality of life, $4.18{\pm}0.74$. The lowest scored question in the 13 question on quality of life was that of frustration related to itching sensation. Significant factors that affect quality of life were severity and home care. These variables explained 21% of variance in quality of life (F=21.17, p<.001). Conclusion: The results indicate that severity of childhood atopic dermatitis and home nursing impact on the quality of life of parents. Using the above findings, health professionals who work with children with atopic dermatitis and their parents need to develop specific nursing interventions that will promote health of children with atopic dermatitis and quality of life in their parents.

Effect of Ingested Caffeine on the Sleep Quality among Shift Workers (교대근무자의 카페인 섭취가 수면의 질에 미치는 영향)

  • Kim, Hyesung;Lee, Jong-Eun
    • Korean Journal of Occupational Health Nursing
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    • v.29 no.4
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    • pp.306-315
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    • 2020
  • Purpose: This study was conducted to identify the effects of caffeine intake by shift workers on sleep, considering various variable related to the sleep health of shift workers. Methods: A descriptive survey study was conducted with 128 employees who worked shifts. Respondents were surveyed on their of caffeine intake behavior, schedule type, quality of sleep, health promotion behavior, and occupational stress. Differences in their quality of sleep were assessed using the t-test and analysis of variance, while factors influencing the effect of caffeine intake on the quality of sleep were analyzed using hierarchical logistic regression. Results: The average Pittsburgh Sleep Index, Korean Version score of those surveyed was 7.3±3.25, indicating that their quality of sleep was low. On the other hand, their aveage daily intake of caffeine was 1.6±0.99 cups (1 cup =150 mL) and 116.4±77.58 mg/dL of caffeine. When the various variables that could have affected the quality of sleep were corrected, an increase in the amount of caffeine consumed was found to lead to a decrease in the quality of sleep (p=.015). Conclusion: Caffeine intake by shift workers has a significant bearing on their quality of sleep; therefore, such intake should be adjusted to improve their sleep health.

Probabilistic Method for The Harmonic Analysis of Railroad Feeding System (철도급전시스템의 고조파 평가를 위한 확률론적 방법)

  • Lee, Seung-Hyuk;Song, Hak-Seon;Lee, Jun-Kyong;Kim, Jin-O
    • The Transactions of the Korean Institute of Electrical Engineers A
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    • v.55 no.9
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    • pp.384-391
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    • 2006
  • The harmonic currents generated along with the operating speed of electrical railroad traction are very difficult to analyze because of its nonlinear characteristics. This paper therefore presents probabilistic approach for the evaluation of harmonic currents about the operating speed of the arbitrary single traction. To use probabilistic method for railroad system, PDF(Probability Density Function) using measuring data based on the realistic h 따 monic currents per operating speed is calculated. Measuring data of harmonic current per operating speed is obtained using the result data of PSCAD/EMTDC dynamic simulation based on an IAT(Intra Airport Transit) in Incheon International Airport. The means(expected values) and variances of harmonic currents of single traction also are obtained by the PDF of the operating traction speed and harmonic currents. The uncertainty of harmonic currents can be calculated through the mean and variance of PDF. The probability of harmonic currents generated with the operating of arbitrary many tractions is calculated by the convolution of functions. The harmonics of different number of tractions are systematically investigated to assess the TDD(Total Demand Distortion) for the railroad system. The calculation of TDD was carried out using Monte-Carlo Simulations(MSCs) and the results of TDD evaluation of the power quality in the IAT power feeding system.

Comparison of Diagonal Shoulder Exercises with and Without Distal Wrist and Finger Movement

  • Ann, So-Youn;Park, Se-Yeon;Kim, Jwa-Jun
    • Journal of the Korean Society of Physical Medicine
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    • v.10 no.1
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    • pp.1-7
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    • 2015
  • PURPOSE: The aim of this study was to investigate the effects of distal movement on shoulder muscle activation during diagonal pattern of exercises. METHODS: Seventeen healthy male participants volunteered to participate. Five muscles of shoulder were investigated during standing performance of diagonal shoulder exercises with and without visual trace. Two patterns of the diagonal exercises were used as diagonal 1 flexion and extension (D1F-E), and diagonal 2 flexion and extension (D2F-E). Two way repeated measures analysis of variance was used, which the factor was the presence of distal movement and exercise variations. RESULTS: The average muscle activity values of the lower trapezius and anterior deltoid are higher with the D2F-E, compared to the D1F-E (p<.05). The distal movement effect was observed within included all muscles except the lower trapezius, which the values are significantly greater in exercise with distal movement (P<.05). All significant increase of the muscles during the exercise with distal movement condition showed over 0.9 for the observed power in present study. CONCLUSION: Present result suggested that the diagonal pattern of exercise with distal movement has additional advantages of activating the scapulothoracic muscle as well as glenohumeral muscles. In addition, the D2F-E exercise pattern is effective for activating lower trapezius and anterior deltoid muscles.

A Study on the Visual Evaluation according to Clothing Stimuli and the Method of Presentation (의복자재물(衣服刺載物)과 제시방법(提示方法)에 따른 시각적(視覺的) 평가(評價))

  • Kim, Hee Jung;Lee, Kyoung Hee
    • Journal of the Korean Society of Clothing and Textiles
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    • v.17 no.3
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    • pp.428-435
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    • 1993
  • The purpose of this study was to investigate the difference of the visual evaluation about clothing texture, the state of wearing and the method of presentation. The data from observation were analyzed by factor analysis, t-test, ANOVA, Scheffe test and MCA. The results of this study were as follows ; 1. 17 pairs of discriptors used for the visual evaluation of clothing stimuli were found to include four factor dimensions(total variance 65.6%) ; Attention, Appearance, Texture, Maturity. 2. For the image of clothing texture, there were significant differences in the attention and texture. 3. For the image of the state of wearing, there were significant differences in the attention and appearance. 4. For the image of the method of presentation, there were significant differences in the clothing texture and the state of wearing. 5. According to clothing texture, the state of wearing and the method of presentation, the interaction effect was significant in the attention and appearance.

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