• Journal of the Korean Society for Nondestructive Testing
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• v.32 no.5
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• pp.502-508
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• 2012

Quantitative ultrasound technologies for osteoporosis diagnosis measure ultrasonic parameters such as speed of sound(SOS) and normalized broadband ultrasound attenuation(nBUA) in the calcaneus (heel bone). In the present study, the dependences of SOS and nBUA on bone mineral density in the proximal femur with high risk of fracture were investigated by using 20 trabecular bone samples extracted from bovine femurs. SOS and nBUA in the femoral trabecular bone samples were measured by using a transverse transmission method with one matched pair of ultrasonic transducers with a center frequency of 1.0 MHz. SOS and nBUA measured in the 20 trabecular bone samples exhibited high Pearson's correlation coefficients (r) of r = 0.83 and 0.72 with apparent bone density, respectively. The multiple regression analysis with SOS and nBUA as independent variables and apparent bone density as a dependent variable showed that the correlation coefficient r = 0.85 of the multiple linear regression model was higher than those of the simple linear regression model with either parameter SOS or nBUA as an independent variable. These high linear correlations between the ultrasonic parameters and the bone density suggest that the ultrasonic parameters measured in the femur can be useful for predicting the femoral bone mineral density.

• Journal of the Korean Society of Propulsion Engineers
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• v.23 no.2
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• pp.1-12
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• 2019

A fundamental study on a gas injection variable thrust method for thrust throttling in a liquid rocket engine was conducted. The gas injection variable thrust has the advantage of not only being able to control the thrust with a simple structure but it also increases the atomization performance through the injection pressure drop that increases in direct proportion to the density reduction. In this study, spray characteristics such as spray instability, spray pattern, spray angle, and breakup length based on changes in the liquid mass flow rate and amount of injected gas were investigated using effervescent swirl injectors.

• Journal of the Korean Institute of Intelligent Systems
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• v.14 no.7
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• pp.847-851
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• 2004

In the original mixture density network(MDN), which was introduced by Bishop and Nabney, the parameters of the conditional probability density function are represented by the output vector of a single multi-layer perceptron. Among the recent modification of the MDNs, there is the so-called modified mixture density network, in which each of the priors, conditional means, and covariances is represented via an independent multi-layer perceptron. In this paper, we consider a further simplification of the modified MDN, in which the conditional means are linear with respect to the input variable together with the development of the MATLAB program for the simplification. In this paper, we first briefly review the original mixture density network, then we also review the modified mixture density network in which independent multi-layer perceptrons play an important role in the learning for the parameters of the conditional probability, and finally present a further modification so that the conditional means are linear in the input. The applicability of the presented method is shown via an illustrative simulation example.

• The Journal of the Acoustical Society of Korea
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• v.34 no.4
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• pp.303-309
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• 2015

Speaker diarization is the task of determining the speakers for unlabeled data, and DBSCAN (Density-Based Spatial Clustering of Applications with Noise) has been widely used in the field of speaker diarization for its simplicity and computational efficiency. One challenging issue, however, is that if different clusters in non-spatial dataset are adjacent to each other, over-clustering may occur which subsequently degrades the performance of DBSCAN. In this paper, we identify the drawbacks of DBSCAN and propose a new density clustering algorithm based on local distribution property around object. Variable density criterions for local density and spreadness of object are used for effective data clustering. We compare the proposed algorithm to DBSCAN in terms of clustering accuracy. Experimental results confirm that the proposed algorithm exhibits higher accuracy than DBSCAN without over-clustering and confirm that the new approach based on local density and object spreadness is efficient.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.15 no.6
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• pp.138-149
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• 2016

The study reviewed the effects of the variable speed limit under adverse weather conditions by using a driving simulator. The study assumed that the display of the reduced speed limit without any change of the weather condition and the display of the same speed limit under the change of the weather conditions violate the expectancy of drivers, so it brings the negative effects on the safety. The study regards drivers conformance as the index of the degree of the compliance of driver expectancy, and utilizes the cumulative probability density within the certain range of the speed including displayed speed limit as the quantitative measure of effectiveness. The study reviewed this assumptions by using a driving simulator. As the results, the cases assumed to violate the expectancy of drivers showed the negative effects on the driving behaviour of driver relatively.

• Journal of Korean Society of Transportation
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• v.25 no.6
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• pp.111-120
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• 2007

More accurate vehicle trajectory data are now readily available through Differential Global Positioning Systems (DGPS). A variety of research opportunities emerge with utilization of such high resolution traffic data. A novel approach of this study is to explore drivers' responsive behavior to variable message signs (VMS) by using individual vehicle trajectories extracted from in-vehicle DGPS data. Responsive characteristics of drivers traveling on urban freeways, which can be represented by speeds and acceleration rates, under the provision of real-time traffic information through VMS are statistically investigated. In addition to conducting an ANOVA test, probability density functions of acceleration rates were estimated. The findings of this study can be used to understand the impact of drivers' workload when providing VMS messages on traffic flow patterns. Furthermore, results can be important fundamentals to assist in conducting more realistic traffic simulations.

• Journal of Microbiology and Biotechnology
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• v.27 no.5
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• pp.965-974
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• 2017

The single-chain variable fragment (scFv) against lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is a promising molecule for its potential use in the diagnosis and immunotherapy of atherosclerosis. Producing this scFv in several milligram amounts could be the starting point for further engineering and application of the scFv. In this study, the abundant expression of the anti-LOX-1 scFv was attempted using Escherichia coli (E. coli) and Brevibacillus choshinensis (B. choshinensis). The scFv had limited soluble yield in E. coli, but it was efficiently secreted by B. choshinensis. The optimized fermentation was determined using the Plackett-Burman screening design and response surface methodology, under which the yield reached up to 1.5 g/l in a 5-L fermentor. Moreover, the properties of the scFvs obtained from the two expression systems were different. The antigen affinity, transition temperature, and particle diameter size were 1.01E-07 M, $55.2{\pm}0.3^{\circ}C$, and 9.388 nm for the scFv expressed by B. choshinensis, and 4.53E-07 M, $52.5{\pm}0.3^{\circ}C$, and 13.54 nm for the scFv expressed by E. coli. This study established an efficient scale-up production methodology for the anti-LOX-1 scFv, which will boost its use in LOX-1-based therapy.

• Earthquakes and Structures
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• v.17 no.6
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• pp.557-566
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• 2019

The evaluation of the seismic hazard for a given site is to estimate the seismic ground motion at the surface. This is the result of the combination of the action of the seismic source, which generates seismic waves, the propagation of these waves between the source and the site, and site local conditions. The aim of this work is to evaluate the sensitivity of dynamic response of extended structures to spatial variable ground motions (SVGM). All factors of spatial variability of ground motion are considered, especially local site effect. In this paper, a method is presented to simulate spatially varying earthquake ground motions. The scheme for generating spatially varying ground motions is established for spatial locations on the ground surface with varying site conditions. In this proposed method, two steps are necessary. Firstly, the base rock motions are assumed to have the same intensity and are modelled with a filtered Tajimi-Kanai power spectral density function. An empirical coherency loss model is used to define spatial variable seismic ground motions at the base rock. In the second step, power spectral density function of ground motion on surface is derived by considering site amplification effect based on the one dimensional seismic wave propagation theory. Several dynamics analysis of a curved viaduct to various cases of spatially varying seismic ground motions are performed. For comparison, responses to uniform ground motion, to spatial ground motions without considering local site effect, to spatial ground motions with considering coherency loss, phase delay and local site effects are also calculated. The results showed that the generated seismic signals are strongly conditioned by the local site effect. In the same sense, the dynamic response of the viaduct is very sensitive of the variation of local geological conditions of the site. The effect of neglecting local site effect in dynamic analysis gives rise to a significant underestimation of the seismic demand of the structure.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.34 no.7
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• pp.821-827
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• 2010

This paper proposes a density method based topology optimization of a perpendicular magnetic recording system design in which the saturation effect is taken into account. During the topology optimization process in magnetic fields, the magnetic reluctivity is updated in accordance with the changes in element density determined by a sensitivity analysis. The magnetic reluctivity is determined from a B-H curve and is used to represent nonlinear material property, i.e., the saturation effect. The sensitivity for a generalized response functional is formulated using the adjoint variable method in which the nonlinear property is taken into account and the objective function is set such that the magnetic energy in the media is maximized. Effects due to the nonlinear property can be observed from a numerical study in which the linear and the nonlinear topology optimization results are compared.

• Journal of the Korean Wood Science and Technology
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• v.25 no.2
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• pp.33-44
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• 1997

This study was executed to examine the effects of polypropylene fiber length and process variables of the composites made from wood fiber and nonwood fiber mixed formulations. As a nonwood fiber the polypropylene with 3 denier thickness of tow condition was selected and cut into each length of 0.5, 1.0, 1.5, 2.0 and 2.5cm to mix with wood fiber. And also western hemlock wood fiber for medium density fiberboard was prepared. First, to decide an adequate polypropylene mixing fiber length, the composites of 1.0g/$cm^3$ density were made from 10% polypropylene fiber by each of five lengths and 90% western hemlock fiber mixed formulations. Thereafter as the experiments of process variable, the composites applied with adequate polypropylene fiber length(1.5cm) were made from 4 density levels (0.6, 0.8, 1.0, 1.2g/$cm^3$). 3 mixed formulations of wood fiber to polypropylene fiber(95 : 5, 90 : 10, 85 : 15), and 3 mat moisture contents(5, 10, 20%). According to the results and discussions it was concluded as follows ; The physical and mechanical properties were shown improved tendency. as polypropylene fiber length was increased in the range from 0.5 to 1.5cm, but shown decreasing tendency from 2.0 to 2.5 cm. Accordingly, it was shown that polypropylene fiber length is limited to 1.5cm or less length in mixing wood fiber and polypropylene fiber by turbulent air mixing process. As the densities of wood fiber-polypropylene fiber composites were increased, the physical and mechanical properties were clearly improved. Also they were shown significantly increasement statistically between densities respectively. In the mixed formulations, physical and mechanical properties were shown only slightly improvement, as they changed from 95 : 5 to 85 : 15 in wood fiber to polypropylene fiber. Despite of increasement of mat moisture content, mechanical properties were not improved significantly but physical properties were improved somewhat in wood fiber-polypropylene fiber composites.