• Asian Pacific Journal of Cancer Prevention
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• v.17 no.5
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• pp.2597-2603
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• 2016

Ovarian cancer is a highly malignant neoplasm with high mortality rates. Research to identify markers facilitating early detection has been pursued for many years. Currently, diagnosis is based on the CA 125 and HE4 markers, as well as the ROMA algorithm. The search continues for new proteins that meet the criteria of good markers A total of 90 patients were included in the present study, allocated into: group 1, ovarian cancer, with 29 patients; group 2, endometrial cysts, with 30s; and group 3, simple ovarian cysts, with 31. Following histopathological verification, the CA 125, HE4, and metalloproteinase 3 (MMP3) levels were determined and the ROMA algorithm was calculated for all patients. The mean concentrations of all determined proteins, CA 125, HE4, and MMP3, as well as the ROMA values, were significantly higher in group 1 (ovarian cancer) compared to group 3 (simple ovarian cysts). The highest significant differences for the CA 125 levels (p<0.000001) and ROMA (p<0.000001) values were observed in postmenopausal women. For HE4, statistical significance was at the level of p=0.00001 compared to p=0.002 for MMP3. For the differentiation between ovarian cancer and endometrial cysts, the respective AUC ratios were obtained for CA 125, HE4, and MMP3 levels, as well as the ROMA values ( 0,93 / 0,96 / 0,75 / 0,98). After removing the post-menopausal patients, the MMP3 AUC value for ovarian cancer vs. benign ovarian cysts increased to 0.814. For post-menopausal women, the MMP3 AUC value for ovarian cancer vs. endometrial cysts was 0.843. As suggested by the results above, both the CA 125 and HE4 markers, as well as the ROMA algorithm, meet the criteria of a good diagnostic test for ovarian cancer. MMP3 seems to meet the criteria of a good diagnostic test, particularly in postmenopausal women; however, it is not superior to the tests used to date.

• The Journal of Engineering Geology
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• v.30 no.2
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• pp.161-173
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• 2020

This study is to examine the engineering characteristics of colunmar joints in Mudeugsan National Park, a global geopark. For these purposes, physical and mechanical properties of Mudeungsan Tuff, evaluation for the weathering degree of columnar joints, and crack behavior monitoring in columnar joints were conducted. The physical properties of Mudeungsan tuff were 1.02% for the average porosity, 0.38% for the average absorption, 2.69 g/㎤ for the average specific gravity, and 4,948 m/s for the average elastic wave velocity. Its mechanical properties were 337 MPa for the average uniaxial compressive strength, 68 GPa for the average elastic modulus, 0.29 for the average Poisson's ratio, 41.3 MPa for the average cohesion strength, and 62.8° for the average friction angle. the average rebound Q-value of the silver Schmidt hammer for the three columnar joint blocks at the Ipseok-dae was shown as 49.3. when this value is converted into uniaxial compressive strength, it becomes 70.5 MPa, which is about 21% of the uniaxial compression strength of Mudeungsan tuff. In addition, according to the results of crack monitoring measurements for the three columnar joint blocks at the Ipseok-dae, the crack behavior is less than 1 mm, so it is believed that its behavior in Ipseak-dae columnar joints has hardly occured to date.

• Journal of The Korean Society of Grassland and Forage Science
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• v.38 no.2
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• pp.91-98
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• 2018

This study was conducted in 2014 in the Gangjin area of Jeonnam province for the purpose of confirming the potential of Kenaf as an alternative feed crop of rice. The weather and soil conditions were favorable and there was no adverse effect on the growth of Kenaf. The amount of seeding was given at 10 kg, 15 kg and 20 kg. As the seeding volume increased, plant height and dry matter yield increased, and stem diameter and number of nodes decreased. The highest growth rate was observed between 75 and 90 days from the date of planting(p<0.05). As the growth progressed, stem rate increased and leaf rate decreased(p<0.05). Increased amount of seeding and growth resulted in decreased CP and TDN and increased ADF and NDF, which resulted in the decreased economic value of Kenaf as a feed crop. The result of increasing the use of organic fertilizer to 20 kg and 30 kg was similar to increasing the amount of seeding. As organic fertilizer usage increased, dry matter yield and growth rate improved(p<0.05).

• Journal of the Korean Society for information Management
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• v.30 no.4
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• pp.265-281
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• 2013

The early history of foreign Protestant missionaries in Korea has begun in the late 19th century, when they came to work as professionals such as teachers, medical doctors, etc. as the nation opened its door to western culture with the fall of national isolationism. Their records are considered crucial resources that enable us to shed new light on modern Korean history, politics, economy and society beyond mere religious value. Despite the recognition of such historic value of early missionary resources, however, there has been serious lacking of a systematic attempt to develop policies and plans for making it easy to collect, preserve and access the resources. Up to date, the records of early Protestant missionaries, in diverse forms of mission reports, books, periodicals, personal diaries, letters and photos, are scattered around various places, including their home country churches, governments, libraries, museums, research institutes and homes. Therefore, this research aims at providing basic resources on the archival status of early Protestant missionaries in Korea, needed for developing a sustainable and systematic digital archive system, through the investigation of early foreign missionaries' resources and in-depth interviews of experts. The study covers the period of 1800s to 1910, that is from the beginning of Protestant missionaries entering into Korea until the start of the Japanese annexation in 1910.

• Journal of the Korean Society of Clothing and Textiles
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• v.11 no.1
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• pp.29-42
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• 1987

This study was an attempt to survey, the relationships between women's values and preference in clothing design. For the measurement of values scale was to relect the theoretical, economic aesthetic, social. political and religious values explained by Allport-vernon- Lindzey. The preference rate in clothing design consisted of 50 items and 3 factors including color, form and texture. The questionnaire were administered to a sample of women (between college students and adult) who lined in Seoul, Korea. The date for 910 respondents were analyzed by person's carrelation coefficient, to-test and $x^2$ test. Through this study, the followings were founds; 1. Aesthetic value was the mast important of female college students values and economic value was the most important of adult's values. 2. There were significant relation between values and the preference for clothing form in line and style; 1) In line preference, adult women indicated negative correlation with religious values but positive correlation with aesthetic and political values. 2) In style preference, adult women indicated negative correlation with economic values positive correlation with social values, for female college students indicated positive correlation with aesthetic social and political values. 3. There were significant relation between values and preference for texture in touch, thickness, weight, light and luster; 1) In relationship between texture and values, adult women indicated touchness preference negative correlation with theoretical and religious values, for female college students indicated positive correlation with aesthetic and social values. 2) In thickness preference adult women indicated negative correlation with theoretical values but female college students indicated positive correlation with political values. 3) In weight preference, adult women indicated negative correlation with theoretical values. But female college students indicated positive correlation with religious values. 4) In brightness preference, only adult women indicated positive correlation with social values, negative correlation with economic values. In transparency preference, adult women indicated positive correlation with aesthetic values, negative correlation with religious values. 4. There were significant correlation among color and economic, aesthetic; political and religious values, that is, evacuation and economic political values in adult women there were positive correlation with religious values in female students. 1) In chroma only adult women indicated negative correlation with religious values. In warm and cold, positive correlation with economic values in both of them. 2) In coloration, adult women like a complement color indicated negative correlation with aesthetic values, but positive correlation with political values. 5. There were significant differences in the preference of clothing design between female college students and adult women; correlationship with color variables. Evacuation, both of them indicated negative correlation with chroma positive correlation with warm and cold and coloration. In chroma, adult women indicated negative correlation with coloration and warm and cold, for female students indicated negative correlation with coloration. 6. Comparison with clothing preference: 1) In color preference, adult women liked the most white, brown, blue and black in sequence. Female college students liked the most white, also the next is blue and pink. 2) Clothing design preference, there was significant difference in warm and cold and coloration, adult women more liked than female students. In shape of clothing, both of them indicated significant difference in line and style, female students more liked sporty style. In texture, adult women more liked soft thin light weight and bright. 3) In silhouette preference, the most is H-line, female college students more liked.

• Journal of Life Science
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• v.28 no.3
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• pp.351-356
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• 2018

L-Serine dehydratase (LSD) is an iron-sulfur containing enzyme that catalyzes the conversion of L-serine to pyruvate and ammonia. Among the bacterial amino acid dehydratases, it appears that only the L-serine specific enzymes utilize an iron-sulfur cluster at their catalytic site. Moreover, bacterial LSDs are classified into four types based on structural characteristics and domain arrangement. To date, only the LSD enzymes from a few bacterial strains have been studied, but more detailed investigations are required to understand the catalytic mechanism of various bacterial LSDs. In this study, LSD type II from Mycobacterium tuberculosis (MtLSD) H37Rv was expressed and purified to elucidate the biochemical and catalytic properties using the enzyme kinetic method. The L-serine saturation curve of MtLSD exhibited a typically sigmoid character, indicating an allosteric cooperativity. The values of $K_m$ and $k_{cat}$ were estimated to be $59.35{\pm}1.23mM$ and $18.12{\pm}0.20s^{-1}$, respectively. Moreover, the plot of initial velocity versus D-serine concentration at fixed L-serine concentrations showed a non-linear hyperbola decay shape and exhibited a competitive inhibition for D-serine with an apparent $K_i$ value of $30.46{\pm}5.93mM$ and with no change in the $k_{cat}$ value. These results provide insightful biochemical information regarding the catalytic properties and the substrate specificity of MtLSD.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.36 no.1
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• pp.78-88
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• 2018

The purpose of this study is to establish a utilization plan according to the cultural value of Placenta Chamber of King Sejong's Princes. We used SNS to analyze various public perceptions and opinions, collected data and analyzed it. The collection period is from June 01, 2007 to June 30, 2017 (for about 10 years), We gathered data from blogs, cafes, and Knowledge IN that contain keywords related to 'Placenta Chamber', 'Placenta Chamber of Seongju', 'Placenta Chamber of King Sejong's Princes'. and Analyzed using the text mining method of the big date program. Based on the main results of the big data analysis, Placenta Chamber's method of utilization was derived. As a result, major keywords such as King Sejong Great, Prince, Sungju, Feng Shui, culture, preservation, blessing etc were derived. The association of 'world', 'heritage', 'cultural heritage' is high, and the connection of 'Placenta Chamber', 'Gyeongsangbuk-do', 'cultural property' is high, and it was able to confirm the value of Placenta Chamber as a world cultural heritage. and It is necessary to induce visitors to feel stimulation or change of surroundings through facility refurbishment and environmental improvement around Placenta Chamber.

• The Korean Journal of Pesticide Science
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• v.7 no.3
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• pp.216-222
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• 2003

In order to develop effective control methods for Bakanae disease caused by Gibberella fujikuroi (Saito) Ito during rearing of rice seedlings, we investigated the disease resistance of 15 rice varieties to G. fujikuroi and control effect of six seed disinfectants, and tried to improve the using methods of the seed disinfectants. Disease resistance was tested by investigating the disease incidence on each rice cultivar grown in rice seedling box infested with or not infested with G. fujikuroi at 30 days after sowing seeds and 20 days after heading date. The results showed that Hwayongbyeo, Dongjinbyeo, Hwoanbyeo, Nonghobyeo, Nampyeongbyeo, and Hwojinbyeo were resistant G. fujikuroi, meanwhile Keulubyeo, Sobibyeo, Odaebyeo, Junambyeo, Samchonebyeo, Sangjubyeo, and Hwabongbyeo were susceptible. Three seed disinfectants, prochloraz, fludioxonil, and carproamid + thiram + fludioxonil controlled Bakanae disease of rice very well, while bonomyl + thiram, thiophanate-methyl + thiram and thiophanate-methyl + triflumizole did not suppress the disease enough. Water temperature was turned to be an important factor for controlling the disease by treating seed disinfectants. Prochloraz showed 61% control value on the disease at $10^{\circ}C$, but it showed above 95% control value at the range of $30-35^{\circ}C$. It was confirmed that the control effect of seed disinfectants increased with increasing water temperature. Meanwhile soaking period of rice seeds in the suspension of seed disinfectants and chemical dosage had no high relation to control the disease. This results suggest that rice varieties, water temperature, and optimal selection of suitable seed disinfectants are very important to control Bakanae disease effectively.

• Korean Journal of Hospice Care
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• v.5 no.1
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• pp.74-81
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• 2005

Purpose: The purpose of this study is to help apply spiritual care in clinics by testing whether spiritual support like prayer and praise, which is appled on a patient who has been cared for by Facility Hospice can have an effect on their physical pain, emotional anxietv, loneliness and well being. Method: This research was done on a subject patient who had been hospitalized in Saemmul from Jan, 2002 to June, 2003, and who could easily communicate. Questionnaire of quality of life, they had this test from the date of admission into the hospital 1week, 3week, 5week later. The Target was 182 people for the hospital data, 124 people after one week, 84 people after 3 weeks and 54 people after for 5 weeks later. For statistics, SPSS for Window(SPSS inc. ver.10), student T-test and one way ANOVA were used. The interrelation between pray and pain was analyzed by the "Pearson correlation". In case where the P-value was below 0.05, we concluded it had statistical-value. Results: When we compared both the party which had a low degree of peace by prayer and praise and the B party which had the highest degree, B party had an increasing tendency for less anxiety and loneliness and more well-being. Each of the data 0, 1, 3 and 5 week showed visible difference between both parties. Conclusion: First, in case that a late cancer patient is hospitalized, the difference for tranquility and pain control by prayer and praise is not noticeable. While, 1 and 3 weeks later, the difference is visible, so we concluded the relationship between the cancer patient's spiritual tranquility and physical pain are closely related with each other. Also the patients who are in spiritual peace by prayer and praise can control the pain better than the other patients. Second, because the patient who can feel calm from the data of being admitted into the hospital is mentally calm, both party's difference is noticeable in each period of the 1, 3 and 5th week. Compared with other patients, the object patients who have spiritual tranquility will have less anxiety and loneliness and more tranquility.

• The Korean Journal of Zoology
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• v.33 no.4
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• pp.499-508
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• 1990

Surveys of elecirophoretic variations in isozymes and proteins encoded by 25 persumtive loci were conducted to estimate the degree of genic variation and to assess species recognition for three species of the Family Gasterosteidae (Pisces) in Korea. The average degree of genic variation of Gasterosteus aculeatus was HD = 0.086, HG = 0.084, and P =36% and it was similar to Pungitius sinensis (HD = 0.080, HG = 0.091, P = 29%). But P.kaibarae was less variable than these species (HD = 0.034; HG = 0.034, P = 13%). The average genetic similarities among the populations in each species of Gasterosteus aculeatus pungitius sinensis and P. kaibarae were S = 0.963, S = 0.953 and S = 0.800 respectively.Yongchon and Kyongiu populations of P. kaibarae were genetically remote from the rest of the conspecific populations (S = 0.690). Chae (1988) also observed morphological differences between them. The value of genetic similariiy coefficients of S = 0.606 between P. sinensis and P. kaibarae is low enough to consider as specific level of genetic difference, but moderate rate of hybridization (44%) between them at a synpatric area of Kangnung indicates that isolating mechanism is incomplete. Therefore it is concluded that P. sinensis and P. kaffarae are semispecitic status. Intergeneric genetic similarities between the genus Gasrerosteus and Pungitius were S = 0.052 and this value is the lowest estimate up to date in freshwater fishes.