• Bulletin of the Korean Chemical Society
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• v.33 no.6
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• pp.1885-1889
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• 2012

Among 23 cytochrome P450s, CYP125A4 was proposed as a putative monooxygenase based on the high level of amino acid sequence homology (54% identity and 75% similarity) with the well characterized C27-steroid $Mycobacterium$ $tuberculosis$ CYP125A1. Utilizing MTBCYP125A1 as a template, homology modeling of SPCYP125A4 was conducted by Accelrys Discovery Studio 3.1 software. The modeled SPCYP125A4 structure with lowest energy value was subsequently assessed for its stereochemical quality and side-chain environment. The final model was generated by showing its active site through the molecular dynamics. The docking of steroids showed broad specificity of SPCYP125A4 with different orientation of ligand within active site facing the heme. One poses of C27-steroid with C26 facing the heme with distance of 3.734 ${\AA}$ from the Fe were predominant.

• Proceedings of the Korean Society of Embryo Transfer Conference
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• 1998.05a
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• pp.12-28
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• 1998

The technology of creating transgenic animals has a potential value in improving productivity and disease resistance of animals, gene therapy, drug pharming and production of model animals for certain diseases. Up to date, fairly low success rate of production of transgenic animals and a pronounced variability with respect to the expression of transgenes have been much observed. The mechanisms how to integrate the injected genes with a certain part of the genomes are unknown yet. Many techniques in gene transfer, beside microinjection, have been introduced and explored thus to improve the production efficiency of transgenic animals. In this article, the methods and efficiency of gene-transfer techniques, the detection and preselection of transgenes in embryos by PCR- and GFP-screenings and cloning of preselected transgenic embryos by nuclear transplantation are described and discussed. Some experimental results showed that the early screening and selection of integration of the injected gene with embryonic genome by polymerase chain reaction(PCR) and green fluorecence protein(GFP) were promising methods. Further, the application of nuclear transplantation technology to cloning and multiplication of the positively integrated genes in the cleaving embryos and embryonic cells will be beneficially used for the mass production of transgenic embryos and consequently improving the production efficiency in transgenic animals.

• IE interfaces
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• v.20 no.2
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• pp.216-226
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• 2007

In code-division multiple-access (CDMA) systems with soft handoff, mobile station (MS) within soft handoff region can use multiple radio channels and receive their signals from multiple base stations (BSs) simultaneously. In this paper, the effects of soft handoff region ratio (SHRR) on reverse link of a CDMA cellular system are analytically investigated. In order to analyze the network performance and quality of service (QoS) perceived by users more realistically, both the soft capacity increasing factor and the traffic load variation affected by SHRR are jointly considered and a two-dimensional continuous time Markov chain (CTMC) model is built. In the numerical example, it is observed that the optimal guard channel exists according the variations of the traffic load and propagation conditions when the proper value of SHRR is determined.

• Journal of Korea Society of Digital Industry and Information Management
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• v.15 no.1
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• pp.1-7
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• 2019

The objective of this study is to examine the trends in big data. Research abstracts were extracted from 4,019 articles, published between 1995 and 2018, on Web of Science and were analyzed using topic modeling and time series analysis. The 20 single-term topics that appeared most frequently were as follows: model, technology, algorithm, problem, performance, network, framework, analytics, management, process, value, user, knowledge, dataset, resource, service, cloud, storage, business, and health. The 20 multi-term topics were as follows: sense technology architecture (T10), decision system (T18), classification algorithm (T03), data analytics (T17), system performance (T09), data science (T06), distribution method (T20), service dataset (T19), network communication (T05), customer & business (T16), cloud computing (T02), health care (T14), smart city (T11), patient & disease (T04), privacy & security (T08), research design (T01), social media (T12), student & education (T13), energy consumption (T07), supply chain management (T15). The time series data indicated that the 40 single-term topics and multi-term topics were hot topics. This study provides suggestions for future research.

• The Journal of Economics, Marketing and Management
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• v.7 no.4
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• pp.1-5
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• 2019

Purpose - Along with the rapid growth of the economics and IT industry, E-commerce appears as the next potential area of world economics. For this no-entity shops commerce style, logistics is crucial for the success of E-commerce. Research design, data and methodology - In this paper, Dangdang.com, the largest online marketplace in China, is studied and a conceptual model is present, to develop a practical way to develop the logistics system in E-commerce situation. Results - This research finds that following 4 factors are critical success factors for E-commerce logistics: 1) logistics centres are very important to control the inventory management; 2) keep good cooperation with third-party logistics (3PL) can guarantee good quality shipping service and also can reduce delivery costs; 3) build strong information system; 4) quick response system also needed for an efficient logistics system. When E-commerce firms are developing their logistics systems, they should pay more attention to these 4 critical success factors. Conclusions - In summary, successful 3PL management is vital for competing regionally and globally throughout the logistics value chain. We see information system as an enabler in logistics management to get the right products to the right place in the right quantity at the right time and to provide quality services to satisfy the customer's needs.

• Journal of Auto-vehicle Safety Association
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• v.15 no.4
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• pp.39-47
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• 2023

Research on the safety of autonomous vehicle is being conducted in various countries, including the European Union, and computer simulation techniques so called 'Virtual Tool Chain' are mainly used. As part of the crash safety study of autonomous vehicle, 25 car to car collision scenarios were provided as a result of a real accident-based accident reproduction analysis study conducted by a domestic research institution, and a vehicle crash analysis was performed using the FE car to car model of the Honda Accord. In order to analyze the results of the car to car simulation and to construct a database, major crash parameters were selected as impact speed, angle, location, and overlap, and a method of defining them in an indexed form was presented. In order to compare the crash severity of each scenario, a value obtained by integrating the resultant acceleration measured by the ACU of the vehicle was applied. The equivalent collision test mode was derived by comparing the crash severity of the regulation test mode, 30 deg rigid barrier mode, in the same way.

• Journal of Venture Innovation
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• v.1 no.1
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• pp.67-82
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• 2018

Lately, recognition of Corporate Social Responsibility (CSR) has been changing. CSR turned out to be a powerful tool which a company incorporates to improve its image. Nowadays, it is no longer an option, but a shared sense which is a source of corporate growth and competitiveness. CSR has changed with times and the economic environment, especially as the global value chain (GVC) came to be more vital, it became accepted as an effective means of growth strategy for small and medium exporters. For SMEs exporters, participating in GVC requires that they meet international standards for CSR demanded by global enterprises. Reflecting this trend, exporters should strive to achieve both goals of social responsibility fulfillment and efficient growth through CSR activities. As one of the key measures for a sustainable growth of an organization, the following are the policy implications. First, it is necessary to establish a national organization dedicated to CSR for small businesses. The central government should establish an organization which is exclusively responsible for CSR of SMEs and oversee the task of CSR of small businesses. Second, the development and verification of the CSV evaluation model should be promoted. The international trend of CSR should be promptly spread out to individual firms and supported to maximize economic effects through consultancy. Third, it should be linked to global advancement. CSR reports by small and mid-size businesses will have to be written to ensure that they have a real effect on the global value chain.

• Journal of Navigation and Port Research
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• v.28 no.1
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• pp.51-58
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• 2004

Due to the changes in market place, new business types(e.g. e-business} have been rapidly emerged and increased. However, those new business types have not much been emerged in port and logistics related industries, and adoption rate of e-business in this area is very low, compared to other industries. Thus, to promote e-business in this area, many policies have been studied. However, most of previous studies have not been based on industrial structure, and results of these studies have mostly been case by case. Further, there have been no research based on the related theories. As a result, despite many of research and project for shipping and port related e-business, prominent achievements in this area have never to be presented. For these reasons, it am be stated that, first of all, basic studies related to new business types in shipping and port are needed, and then, various policies based on results of those basic studies should be discussed. The aim of this study is to classify business types existed (or expected) in a port related industry, ship bunkering. This taxonomy was based on theories related to business layer(BL) and value chain(VC), and these BL and VC combination enabled to acquire all possible business types.

• Journal of Korea Port Economic Association
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• v.27 no.4
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• pp.73-90
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• 2011

Global companies regard the conditions of a location as one of the most crucial factors to assess the competitiveness of ports and the port hinterland, as well as emphasize creation of throughput and the importance of value added logistics in the hinterland under diffusing Supply Chain Management(SCM). This study deals with the evaluation of competitiveness in 7 hinterlands and the establishment of assessment model in hinterland. This study analyzes the importance of factors for the port hinterland competitiveness using AHP method. As a result, logistics factor, accounting for 62.3%, is shown as the relative more important factor, followed by hinterland's economy factors(27.3%) and city/policy factor(10.4%). The result implicates that measures to activate logistics factors with relatively high importance are essentially needed in order to improve the competitiveness of the hinterland of Busan New Port. Especially, it is needed to establish service routes of the port and air networks and to expand infrastructure for support. This study also assesses the competitiveness of hinterlands for the seven domestic and foreign ports based on importance of assessment factors for the hinterland competitiveness using AHP analysis. Busan(3.903) is ranked fourth behind Singapore(4.570), Hong Kong(4.357) and Shanghai(4.042) in assessment.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2003.05a
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• pp.298-303
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• 2003

Due to the changes in market place, new business types(e.g. e-business) have been rapidly emerged and increased. However, those new business types have not much been emerged n shipping and port related industries, and adoption rate of e-business in this area is very low, compared to other industries. Thus, to promote e-business in this area. many policies have been studied. However, most of previous studies have not been based on industrial structure, and results of these studies have mostly been case by case. Further, there have been no research based on the related theories. As a result, despite many of research and project for shipping and port related e-business, prominent achievements in this area have never to be presented. For these reasons, it can be stated that, first of all, basic studies related to new business types in shipping and port are needed. For these reasons, it can be stated that, first of all, basic studies related to new business types in shipping and port are needed, and then, various policies based on results of those basic studies should be discussed. The aim of this study is to classify business types existed (or expected) in a port related industry, ship bunkering. This taxonomy was based on theories related to business layer(BL) and value chain(VC), and these BL and VC combination enabled to acquire all possible business types.