• Journal of computational fluids engineering
• /
• v.7 no.4
• /
• pp.8-18
• /
• 2002

The primary objective of the present study is evaluation of the k-ε-vv-f turbulence model for prediction of natural convection in a rectangular cavity. As a comparative study, the two-layer k-ε model is also considered. Both models, with and without algebraic heat flux model, are applied to the analysis of natural convection in a rectangular cavity. The performances of turbulence models are investigated through comparison with available experimental data. The predicted results of vertical velocity component, turbulent heat fluxes, turbulent shear stress, local Nusselt number and wall shear stress are compared with experimental data. It is shown that, among the turbulence models considered in the present study, the k-ε-vv-f model with an algebraic heat flux model predicts best the vertical mean velocity and velocity fluctuation, and the inclusion of algebraic heat flux model slightly improves the accuracy of results.

• Bulletin of the Korean Chemical Society
• /
• v.7 no.3
• /
• pp.241-245
• /
• 1986

The vibration-vibration energy exchange of $N_2(v=1)+O_2(v=0){\to}N_2(v=0)+O_2(v=1)$ has been investigated, in particular, at low temperatures. The energy exchange rate constants are calculated by use of the solution of the time-dependent Schrodinger equation with the interaction potential of the colliding molecule as a perturbation term. The predicted rate constants are significantly agree with a experimental values in the range of 295∼$90^{\circ}K$. The consideration of the VV-VT coupling decreases the predicted pure VV energy exchange value by a factor of ∼2. When the collision frequency correction is introduced, the VV-VT rate constant is consistent with the observed value in the liquid phase. The consideration of the population of the rotational energy level increases the VV-VT value significantly.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
• /
• v.8 no.3
• /
• pp.285-294
• /
• 2003

To select an appropriate sampler for the environmental monitoring survey in coastal waters of Saemangeum, Jeollabuk-do, a macrobenthic sampling was conducted in April 2002. Employed samplers were dredge (type Charcot), a semi-quantitative sampler and Smith-McIntyre (SM) and van Veen grab (VV) as quantitative ones. One haul was tried for dredge and 3 replicates (0.1 ㎡${\times}$3) for SM and W at each of 11 stations. Comparisons of sediment volume in sampler bucket and of precision of biological parameters (i.e., density, biomass, species number and diversity index, H') were made between SM and VV. Sediment volume was significantly different (SM > VV) at p-value of 0.0050 (paired t-test) and, in average, 3 replicate samples of SM and VV satisfied a precision level of 0.2 by applying 4th root transformation. Patterns of observed and expected species numbers and H' were compared. Dredge-VV samples showed higher affinity than any other pair. Several dominant species in the area were underestimated in dredge samples (e.g., polychaete Heteromastus filiformis. Aricidea assimilis etc.). Quantifying the agreement pattern of multi-species responses was accomplished by estimating correlations between similarity matrices. Correlation between dredge and VV was slightly higher, but near-per-fect matches were found in general. Different ranks and composition among principal species lists were presumably linked to the effect of penetration depth that differs among samplers. Lower level of some species' abundance in VV samples (ca. 50％ compared with those of SM) was explained in this context. It seem appropriate to regard the effect as a probable cause of relatively higher correlations in dredge-VV, Overall bio-logica1 features indicated that a better choice could be SM in situations of requiring high data quality. The others work well, however, on observing and defining faunal characteristics and their capability cannot be questionted if we do not expect a first-order quality.

• Journal of Korean Society of Occupational and Environmental Hygiene
• /
• v.20 no.3
• /
• pp.139-146
• /
• 2010

Recent studies suggest that prolonged standing at work is associated with varicose veins (VV). The objective of this study was to analyze the differences of VV risk in terms of work types in casino dealers and hotel service workers. Symptoms of VV were evaluated using a self-reported questionnaire from 2,092 participants, and muscle fatigue in the lower legs were evaluated using surface electromyography. The shift rate of median frequency in Gastrocnemius was -30.0% among the casino dealers working in prolonged static standing posture, and - 14.3% among the casino dealers sitting during working time. After adjusting age, gender, smoking, and family history of VV, the risk ratio of VV was 3.67(95% CI 2.03-6.59) in group I (prolonged standing and occasional walking at work), 6.29(95% CI 3.48-11.35) in group II (prolonged standing, occasional walking and heavy lifting at work), and 8.07(95% CI 4.51-14.43) in groupIII(prolonged static standing at work). In conclusion, prolonged standing at work may be a work related risk factor of VV.

• Korean Journal of Veterinary Research
• /
• v.29 no.3
• /
• pp.407-416
• /
• 1989

The prospect of live vaccines consisting of genetically modified vaccinia virus expressing foreign genes is exciting, but important issues concerning safety and efficacy need to resolved. Vaccinia virus (VV) is an efficient expression vector with broad host range infectivity and large DNA capacity. This vector has been particularly useful for identifying target antigens for humoral and cell-mediated immunity. The WHO smallpox eradication program, involving the extensive use of VV vaccines, resulted in the late 1970s in the elimination of one of the world's most feared diseases. This achievement is a triumph for preventive medicine and for international collaboration in public health. In 1980, WHO recommended that the routine use of smallpox vaccine should be stopped. Against this background, the prospect of li ve vaccines consisting of genetically modified VV expressing foreign antigens arising from the work of Moss, and Paoletti and their colleagues in 1982 has been greeted with enthusiasm. These investigators have shown that genes coding for immunogenic proteins can be inserted into VV DNA without impairing the ability of the virus to grow in cell culture. Moreover experimental animals infected with VV recombinants containing genes coding for a variety of immunizing proteins have been shown to be protected against challenge infection with the corresponding infectious agent. In this communication, I describe current progress in the construction of a novel plasmid vector that facilitate the insertion and expression of foreign genes in VV as well as the selection of recombinants.

• Journal of the Korea Society for Simulation
• /
• v.19 no.4
• /
• pp.189-198
• /
• 2010

Conceptual Model of the Mission Spaces(CMMS) is a first abstraction model of the military real world and serves as a knowledge(mission spaces) reference models for development, interoperability and reusability of defense modeling and simulation(M&S) systems, by capturing basic information about entities involved in any mission and their key actions and interactions. Therefore, the completeness of CMMS is the key to success for the quality of M&S systems based on it. To improve quality and credibility of CMMS, the Verification, Validation and Accreditation(VV&A) processes of CMMS is very important. This paper briefly describes the K-CMMS(Korean Conceptual Model of Mission Space) and the VV&A process.

• Journal of the Korean Institute of Telematics and Electronics
• /
• v.25 no.8
• /
• pp.966-971
• /
• 1988

AES was used to study oxygen adsorption due to the oxygen exposure at 300\ulcorner temperature and segregation of impurities due to annealing on polycrystal copper surface. The intensity of peak of CuM2, 3VV and CuL3 VV increased with annealing time and the peak of CKLL increased after Ar ion bombardment. The effect of oxygen adsorption on copper surface at 300\ulcorner was verified by the decreased of peak of CuM2, 3VV and CuL3 VV as oxygen exposure increase. The binding energy of copper atoms gradualy shifts from 0.7eV to 1.5eV of copper atoms gradually shifts from 0.7eV to 1.5eV after a oxygen exposure. After the oxygen exposure, the width at half the height of CuM2, 3VV is larger 2V*C/S by the effect of chemical liaison of the copper aton with oxygen atom.

• The Journal of the Korean Society for Microbiology
• /
• v.35 no.3
• /
• pp.251-261
• /
• 2000

V. vulnificus is an estuarine bacterium which causes septicemia and shock in susceptible patients. The organism produces a hemolytic cytolysin (VvH), which has a membrane damaging effect on erythrocytes. To clarify the mechanisms by which VvH might contribute to virulence, we examined its effect on macrophages. When mouse peritoneal macrophages were harvested and co-cultured with hemolysin-positive V. vulnificus strains (100 bacteria/cell), about 60% of the macrophages were killed; macrophages were not killed when co-cultured V. vulnificus strain CVD 707, a VvH-negative deletion mutant. Exposure of macrophages to filtered culture supernatants (2.5 HU/ml) and purified VvH (3 HU/ml) resulted in an increase in dead cells (80 and 90%, respectively), as determined by the trypan blue dye exclusion method and LDH release from macrophages was also increased (70 and 65.5%, respectively). The cytotoxic effect of VvH on macrophages was both the dose- and time-dependent. The VvH caused damage to the macrophage membrane and was blocked significantly by preincubation with cholesterol (p<0.01). Fetal bovine serum showed remarkable inhibition of VvH synthesis by V. vulnificus and inhibited VvH activity in culture supernatant. Cell viability was increased by 35% (p<0.01) and LDH release decreased by 28% (p<0.01) when macrophages were incubated with V. vulnificus (100 bacterial cell) in DMEM-10% FBS for 2 hr. Bacterial clearance activity of mice against V. vulnificus CVD 707 was decreased by pretreatment with 10 HU of VvH. This result suggests that the VvH can impair the membrane of macrophages and may playa role in the pathogenesis of V. vulnificus septicemia.

• Asian-Australasian Journal of Animal Sciences
• /
• v.9 no.6
• /
• pp.679-684
• /
• 1996

This study evaluates the susceptibility of scaleless mutant chickens to very virulent Marek's disease virus (vvMDV) inoculation. One day old chickens were inoculated subcutaneously with Taiwanese isolates of LTB-1 and LTS-1 strains, and standard strain of Md/5. Compared with the non-inoculated group the vvMDV-inoculated chickens showed decreased body weights and atrophy of lymphoid organs before 35 days old. These results indicate that scaleless chickens show the same susceptibility as the wild type chickens to vvMDV infection. Furthermore, the protective effect of herpesvirus of turkey (HVT) vaccination at 1 day old against vvMDV challenge was evaluated. Scaleless mutant chickens of treated groups showed 20-30% early death, and 85.7-100% and 12.5-14.2% had lymphomatous lesions in visceral organs and peripheral nerves, respectively. No significant lesions were observed in non-challenged chickens of the control group. The HVT vaccination did not provide an effective protection against vvMDV infection. It is concluded that scaleless mutant chickens are susceptible to vvMDV infection.

• Proceedings of the Korea Society for Simulation Conference
• /
• 2001.10a
• /
• pp.391-395
• /
• 2001

Model verification, validation and accreditation (VV&A) of system simulation are detailedly discussed in this paper. The necessity of VV&A is explained by analyzing the factors on which the model and the reality are discrepant. The W&A technology is expounded in detail not only in the conceptual aspect but also in the methodological aspect. Some principles, difficulties and problems that should be paid attention to are discussed concretely and reasonedly. The paper is expected to be instructional and helpful to the VV&A study.