• Asian Pacific Journal of Cancer Prevention
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• 제15권20호
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• pp.9039-9043
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• 2014

There is a continuing need for innovative alternative therapies for liver cancer. DNA vaccines for hormone/growth factor immune deprivation represent a feasible and attractive approach for cancer treatment. We reported a preventive effect of a DNA vaccine based on six copies of the B cell epitope GRP18-27 with optimized adjuvants against H22 hepatocarcinoma. Vaccination with pCR3.1-VS-HSP65-TP-GRP6-M2 (vaccine) elicited much higher level of anti-GRP antibodies and proved efficacious in preventing growth of transplanted hepatocarcinoma cells. The tumor size and weight were significantly lower (p<0.05) in the vaccine subgroup than in the control pCR3.1-VS-TP-HSP65-TP-GRP6, pCR3.1-VS-TP-HSP65-TP-M2 or saline subgroups. In addition, significant reduction of tumor-induced angiogenesis associated with intradermal tumors of H22 cells was observed. These potent effects may open ways towards the development of new immunotherapeutic approaches in the treatment of liver cancer.

• 대한화학회지
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• 제35권6호
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• pp.673-679
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• 1991

N-Tert-butylbenzothiazole-2-sulfenamide (TBBS;가황촉진제)의 전기화학적 환원을 직류와 시차펄스 폴라로그래피, 순환 전압전류법, 조절전위 전기량법으로 연구하였다. TBBS의 전극환원과정은 단일 환원파(-2.31 volts vs. Ag/0.1M AgN$O_3$)에서 비가역으로 4전자가 이동하는 E-C-E-C 반응기구로 진행되었다. 조절전위 전기분해 결과 sulfenamide(-S-N=)결합이 끊어지고 mercaptobenzothiazole (MBT)과 유리된 황 그리고 benzothiazole disulfide (MBT dimer) 등이 생성물로 얻어졌다. 생성물의 분석결과와 pH변화에 따른 폴라로그램의 해석을 바탕으로 전기화학적 반응기구를 제안하였다.

• 대한화학회지
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• 제35권6호
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• pp.680-688
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• 1991

N-Oxyldiethylenebenzothiazole-2-sulfenamide (ODBS;가황산촉진제)의 전기화학적 환원을 직류와 시차펄스 폴라로그래피 순환 전압전류법, 조절전위 전기량법으로 연구하였다. ODBS의 전극환원과정은 단일 환원파(-1.86 volts vs. Ag/0.1 M AgN$O_3$in AN)에서 비가역으로 3전자가 이동하는 E-C-E-C 반응 메카니즘으로 진행되었다. 조절전위 전기분해 결과 SULFENAMIDE(-S-N=) 결합이 끊어지고 mercaptobenzothiazole(MBT)과 benzothiazole disulfide(MBT dimer) 그리고 유리된 sulfur 등이 생성물로 얻어졌따. pH 변화에 따른 폴라로그램의 해석과 생성물 분석의 결과를 바탕으로하여 전기화학적 반응 메카니즘을 제안하였다.

• 대한화학회지
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• 제30권5호
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• pp.433-440
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• 1986

反陽性子性 溶媒인 dimethylsulfoxide中에서 p-nitrobenzeneazoresororcinol<4n-BAR>에 대하여 직류 폴라로그래피적 거동을 조사하였다. 0.05M $NaClO_4$의 DMSO溶媒中에서 4n-BAR은 1電子 2段階의 還元過程을 거쳐 hydrazo기를 포함하는 化合物로 還元된다. 還元反應의 中間 生成物은 比較的 反陽性子性 溶媒 속에서 安定하였다. 各 段階의 還元電流는 擴散支配的이었으며 一部 反應電流도 包含되었다. 酸을 添加함에 따라서 2個의 還元波가 하나로 合致되며 [acid]/[reductant]의 몰 (M)비가 M = 2인 條件에서 加電位(-E)에 대해 $log(i_d-i)(Mi_d/2-i)/i$/의 可逆性은 1電子 2段階 還元反應이고 非可逆的이었다.

• 상하수도학회지
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• 제7권1호
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• pp.13-19
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• 1993

Anaerobic Digestion of thickened septage was investigated in this study. Thickening could reduce the volume of septage to be treated to about 40% with 12hr HRT. The VS and BOD removal efficiencies were respectively 28 to 45%, and 75% when digested the thickened septage with 30 day HRT Or $1.4kgVS/m^3/d$. The BOD removal efficiency could be increased to about 90% with subsequent settling tank with about 6 hours HRT. The gas production rate was 0.22 to $0.35m^3gas/kgVSadd$($0.75m^3gas/kgVSrm$), or $1.32m^3gas/kgBOD_{rm}$. In addition, the supernatant of thickener could be returned to the aeration tank treating domestic sewage. In this case, a BOD loading rate of 0.5 to $0.7kgBOD/m^3/d$ or 0.5kgBOD/kgMLVSS/d was proposed for 80% BOD reduction.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2002년도 전력전자학술대회 논문집
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• pp.343-346
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• 2002

In recent, complex SVPWM (Space Vector PWM) algorithm can be easily implemented by high performance microprocessor and DSP. Various SVPWM techniques are widely studied due to the advantages of low harmonic distortion and high use ratio of D.C. link voltage. Most of various studies for improving of VS-PWM inverter performance are concentrated about switching pattern and zero pulse pattern split algorithms. However, dc link voltage that is determined at rated load and speed conditions is not proper in the low speed and under rated load. In this paper, analysis of current ripple with digitally implemented SVPWM inverter is introduced according to link voltage. The optimal link voltage in the designed inverter system and load condition is provided in order to suppress output voltage error and current ripple. As remaining the effective voltage vector interval per sampling period sufficiently, additional voltage error and current ripple are suppressed. The proposed algorithm is verified through digital simulation and experimental results.

• 한국미생물·생명공학회지
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• 제24권2호
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• pp.217-221
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• 1996

Various treatments of naked barley with commercial liquefying enzymes have been emploved to reduce high viscosity of naked barley in cooking as a raw material for alcohol production and to increase alcohol yield. The enzyme BAN used for cooking and liquefaction of naked barley was able to make a reduction of one third of viscosity and to enhance alcohol yield of 4 l/Ton of raw material than the T120L was. Of course, alcohol yield depended in part on the applied saccharifying enzymes. The low temperature cooking of naked barley with BAN was favorable compared with high temperature cooking for both of reducing viscosity (210 vs. 237 cp) and final alcohol yield (Yp/so: 0.397 vs. 0.395 g/g) in industrial scale.

• 한국물환경학회지
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• 제28권6호
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• pp.781-785
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• 2012

This study was carried out to treat the thermal elutriated acids of piggery wastewater using UASB process. The UASB reactor was operated at an organic loading rate (OLR) of $7.4\;kgCOD/m^3-day$ (6.5 ~ 9.0). During the start-up period, the low COD removal efficiency (20%) was caused by shock loading and instability in the reactor. It was mainly due to the high concentration amounts of ammonia nitrogen, which caused inhibitory and toxic effects to toward the anaerobic bacteria. In steady state, the UASB reactor showed a SCOD removal efficiency of 71% and a VS removal efficiency of 39%. The gas production and methane content were 1.3 L/day $(0.21\;m^3\;CH^4/kg$ COD removed) and 77%, respectively.

• 대한화학회지
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• 제11권4호
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• pp.138-142
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• 1967

Zn, Ni 및 Co ion의 陰極反應速度를 Polarograph로써 몇 가지 支持電解液과 溫度에서 Randles法으로 測定하였다. Zn의 速度値는 Randles들의 測定値와 20% 誤差內에서 一致하였다. Ni 와 Co ion에 對한 값은 文獻에 나타나 있지 않으나 前報의 다른 方法에 依한 値와 比較하면 適當한 값이라고 볼 수 있다. Randles法에 依한 速度値를 써서 Kambara들이 提案한 Parameter x,y(z)를 求하고 이들 사이의 關係을 考察하였으며 log y vs. log z 사이에 一種의 曲線關係가 있음을 發見하였다.

• 대한화학회지
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• 제5권1호
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• pp.84-87
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• 1961

A polarographic method for rapid determination of Uranium in the presence of foreign ions was proposed. The method is based on the measurement of polarogram in the sulfuric acid as supporting electrolyte. In this medium Uranyl ions give well defined reduction waves, and half-wave potentials are -0.19V vs. S.C.E. as first wave, and uncertain volt. vs. S.C.E. as second wave in $2.4 N-H_2SO_4.$ The first wave has a linear relationship between the concentration of Uranyl ion and wave height. The author also studied a method for rapid determination of Uranium in Korean monazite sand without eliminating the foreign ions. The Korean monazite sands were analyzed by this method and satisfactory result were obtained.