• Title/Summary/Keyword: VS reduction

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Cost-Effectiveness Analysis in Comparing Alginate Silver Dressing with Silver Zinc Sulfadiazine Cream in the Treatment of Pressure Ulcers

  • Chuangsuwanich, Apirag;Chortrakarnkij, Peerasak;Kangwanpoom, Jupaporn
    • Archives of Plastic Surgery
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    • v.40 no.5
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    • pp.589-596
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    • 2013
  • Background The treatment of pressure ulcers is complicated, given the various wound dressing products available. The cost of different treatments varies and the cost-effectiveness of each product has not been thoroughly evaluated. We compare two wound dressing protocols-alginate silver dressing (AlSD) and silver zinc sulfadiazine cream (AgZnSD) with regard to wound healing and cost-effectiveness Methods Patients with grade III or IV sacral or trochanteric pressure ulcers were eligible for this prospective, randomized controlled trial. The patients were randomized to receive one of the two dressings for an eight-week period. The criteria of efficacy were based on the Pressure Ulcer Scale for Healing (PUSH) scoring tool. The cost of treatment was also assessed. Results Twenty patients (12 women and 8 men) were randomly assigned to receive either AlSD (n=10) or AgZnSD cream (n=10). The demographic data and wound characteristics were comparable in the two groups. The two groups showed no significant difference in the reduction of PUSH score, wound size, or volume of exudate. The tissue type score was significantly lower in the AlSD group ($3.15{\pm}0.68-1.85{\pm}0.68$ vs. $2.73{\pm}0.79-2.2{\pm}0.41$; P=0.015). The cost of treatment was significantly lower in the AlSD group (377.17 vs. 467.74 USD, respectively; P<0.0001). Conclusions Alginate silver dressing could be effectively used in the treatment of grade III and IV pressure ulcers. It can improve wound tissue characteristics and is cost-effective.

Dehydrocoupling of Bis(silyl)alkylbenzenes to Network Polysilanes, Catalyzed by Group 4 Metallocene Combination

  • Kim, Myoung-Hee;Lee, Jun;Moo, Soo-Yong;Kim, Jong-Hyun;Ko, Young Chun;Woo, Hee-Gweon
    • Journal of Integrative Natural Science
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    • v.3 no.1
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    • pp.1-6
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    • 2010
  • Bis(silyl)alkylbenzenes such as bis(1-sila-sec-butyl)benzene (1) and 2-phenyl-1,3-disilapropane (2) were synthesized in high yields by the reduction of the corresponding chlorosilanes with $LiAlH_4$ in diethyl ether. The dehydrocoupling of 1 and 2 was performed using group IV metallocene complexes generated in situ from $Cp_2MCl_2$/Red-Al and $Cp_2MCl_2$/n-BuLi (M = Ti, Hf), producing two phases of polymers. The TGA residue yields of the insoluble polymers were in the range of 64-74%. The molecular weights of the soluble polymers produced ranged from 700 to 5000 ($M_w$ vs polystyrene using GPC) and from 500 to 900 ($M_w$ vs polystyrene using GPC). The dehydropolymerization of 1 and 2 seemed to initially produce a low-molecular-weight polymer, which then underwent an extensive cross-linking reaction of backbone Si-H bonds, leading to an insoluble network polymer.

Comparison of Calorie Intake and Satiety Rate by Different Energy Density Level of Kimbab (에너지 밀도 차이에 따른 김밥의 섭취량 및 포만도 비교)

  • Chang, Un-Jae;Jun, Seung-Chol;Park, Hyo-Jung;Hong, In-Sun;Jung, Eun-Young
    • Journal of the Korean Dietetic Association
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    • v.14 no.4
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    • pp.396-403
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    • 2008
  • We attempted to determine whether energy density would influence calorie intake via cognitive cues, as reflected by satiety. This experiment was designed using two different energy density levels of Kimbab: normal Kimbab (1.6 kcal/g) vs low-density Kimbab (1.0 kcal/g). 26 female college students participated in this study. The subjects ate Kimbab in the lab once a week for 2 weeks. Each week at noon, they were served 24 units of either normal or low-density Kimbab, and we determined the units, grams, and calories of the real & cognitive intake of Kimbab, and also analyzed the satiety rate after eating Kimbab. Our results demonstrated that the real calorie intake from the low-density Kimbab was significantly lower than that of the normal Kimbab (290.3 kcal vs 474.4 kcal, p<0.001), but we noted no significant differences in the units and grams of real and cognitive intake between the normal and low-density Kimbab. However, despite consuming 39% lower caloric intake, the subjects reported similar levels of satiety rates with the two different density levels of Kimbab, as they did not perceive themselves to have eaten more normal Kimbab than low-density Kimbab. Thus, this study provides evidence that the energy density of food is a crucial determinant of caloric intake, and supports the notion that the consumption of low energy-dense foods may result in a reduction of caloric intake without altering satiety.

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Relationship between Diabetes Mellitus and Anemia in Korean Adults-Based on the Korean National Health and Nutritional Examination Survey VI (제6기 국민건강영양조사를 토대로 분석한 한국 성인의 당뇨병과 빈혈 관계)

  • Lee, Ae-Ri;Yun, Jung-Mi
    • Journal of the Korean Dietetic Association
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    • v.23 no.1
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    • pp.54-63
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    • 2017
  • Anemia, defined as a reduction in the hemoglobin concentration of blood, is common in diabetes mellitus (DM) patients, can be potentially caused by diabetes complications such as nephropathy. Recent research suggests that diabetes mellitus (DM) itself may be a major risk factor of anemia. However, there are few Korean studies on the relationship between diabetes mellitus (DM) and anemia. This study was performed to investigate the association between anemia and diabetes mellitus (DM) in Korean adults. A total of 10,151 Korean adults over aged 19 years (4,422 male, 5,729 female) were selected from the participants of the Korean National Health and Nutrition Examination Survey VI (KNHANES VI). Korean adults with anemia had a higher prevalence of diabetes mellitus (DM) than the normal adults (11.4% vs. 30.4% in male, 8.8% vs. 9.4% in female). The unadjusted odds ratio (OR) for anemia was greater in adults with DM than in normal male (OR=3.28; 95% CI: 2.27~4.73). After adjusting for other risk factors including age, education, family income, smoking, drinking, and menstrual status, anemia and diabetes were not associated (OR=1.33; 95% CI: 0.84~2.09). Similarly, there was no association between anemia and diabetes in female. In conclusion, this study shows that the prevalence of anemia is similar in diabetic and non-diabetic Korean adults after adjusting for multiple risk factors. Further research is required to elucidate the mechanism of anemia caused as a consequence of diabetes mellitus (DM).

Recovery of Metallic Lithium by Room-Temperature Electrolysis: I. Effect of Electrode Materials (상온(常溫) 전해법(電解法)에 의한 리튬 금속(金屬)의 회수(回收): I. 전극물질(電極物質)의 영향(影響))

  • Lee, Jae-O;Park, Jesik;Lee, Churl Kyoung
    • Resources Recycling
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    • v.21 no.6
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    • pp.45-50
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    • 2012
  • The room-temperature electrodeposition of metallic lithium was investigated from ionic liquid, 1-methyl-1-propylpiperidinium bis(trifluoromethanesulfonyl)imide (PP13TFSI) with lithium bis (trifluoromethanesulfonyl)imide (LiTFSI) as a lithium source. Cyclic voltammograms on gold working electrode showed the possibility of the electrodeposition of metallic lithium, and the reduction current on a gold electrode was higher than the value on platinum and copper. The metallic lithium could be electrodeposited on the gold electrode under potentiostatic condition at -2.4 V (vs. Pt-QRE) and was confirmed by analytical techniques including XRD and SEM-EDS. The dendrite-typed electrodeposits were composed of a metallic lithium and a alloy with gold substrate. And any impurity could be detected except for trace oxygen introduced during handling for the analyses.

Short-term Comparison of Supervised Rehabilitation and Home-based Rehabilitation for Earlier Recovery of Shoulder Motion, Pain, and Function after Rotator Cuff Repair

  • Song, Si-Jung;Jeong, Tae-Ho;Moon, Jung-Wha;Park, Han-Vit;Lee, Si Yung;Koh, Kyoung-Hwan
    • Clinics in Shoulder and Elbow
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    • v.21 no.1
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    • pp.15-21
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    • 2018
  • Background: This study was undertaken to compare the outcome of supervised and home exercises with respect to range of motion (ROM), pain, and Single Assessment Numeric Evaluation (SANE). We further correlated the ROM recovery and pain reduction as well. Methods: The study included 49 patients who underwent arthroscopic rotator cuff repair. Rehabilitation was initiated after 4 weeks of immobilization. A total of 29 patients performed supervised exercise 3 times a week. Standardized education and brochures for review were provided to the remaining 20 patients who insisted on home rehabilitation. Statistical analysis was performed for comparing pain Numerical Rating Scale (NRS), SANE, and ROM. In addition, we also evaluated the correlation between pain and ROM. Results: Comparison of the two groups revealed no significant differences in forward flexion, internal rotation, abduction, and pain NRS. However, SANE at the 9th week (63.8 vs. 55.0, p=0.038) and improvement of external rotation from the 5th to the 9th week (17.6 vs. 9.3, p=0.018) were significantly higher in the supervised exercise group as compared to the home exercise group. Correlation of pain NRS with forward flexion, external rotation, internal rotation and abduction were statistically not significant (correlation coefficient=0.032 [p=0.828], -0.255 [p=0.077], 0.068 [p=0.642], and -0.188 [p=0.196], respectively). Conclusions: The supervised rehabilitation after arthroscopic rotator cuff repair showed better improvement in external rotation and higher SANE score after 4 weeks of rehabilitation exercise. However, no statistically significant correlation was observed between the recovery of ROM and short-term pain relief.

Effect of Hydraulic Loading Rate of a Continuous Stirred Tank Reactor(CSTR) on the Removal Efficiency of Pollutants of Pig Slurry (CSTR의 수리학적 부하율이 돈슬러리의 유기물 및 영양염류 저감효율에 미치는 영향)

  • 정우철;최홍림
    • Journal of Animal Environmental Science
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    • v.5 no.3
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    • pp.189-196
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    • 1999
  • Anaerobic digestion is a naturally occuring microbial process involving the decomposition of organic materials such as livestock manure. This study explores the effect of the operating conditions, HRT (Hydraulic Retention Time) and feeding frequency on treatment efficiency for digestion of pig slurry, which has been one of most difficult organic waste for proper treatment in livestock production industry in Korea at the present time. The pilot-scale CSTR of 5 m3 in volume was designed. manufactured, and operated at the temperature of 35$\pm$1$^{\circ}C$. The digester was designed to hydraulically stir for complete mixing and to supply heat from the water bath to maintain mesophilic temperature. The HRT of the digester for Test 1 and Test 2, and Test 3 was set for 17 days and 13 days respectively and pig slurry was fed once a day with 300$\ell$ each for Test 1 and Test 3, while twice with 150$\ell$each for Test 2. Test 2 showed better performance by increase of 4% in VS removal efficiency and 5% in biogas production rate. This is mainly attributed to smaller temperature drop by feeding frequently with half amount, which eventually led to lesser impact on anaerobic mocrobes in the digester. Test 2 maintained optimum pH 7.8 which uplifted the activaton of sulfur-reduction bacteria, alkalinity of around 4,000mg/$\ell$, VA of over 3,000mg/$\ell$ for whole period of experiment. Further research may require to provide the practical operation strategy of anaerobic treatment system for treatment of pig slurry.

A Study on the Quality and Biological Characteristics of Moss Panel Utilizing Alumina Cement (알루미나 시멘트 활용 이끼 판넬의 품질 및 생물학적 특성에 관한 연구)

  • Choi, Yun-Wang;Oh, Sung-Rok;Kim, Cheol-Gyu;Lee, Jae-Heun
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.7 no.1
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    • pp.57-65
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    • 2019
  • In this study, the quality characteristics of the mother material of panel were evaluated for the production of moss panel using alumina cement and biological characteristics and environmental impact characteristics of moss panel were evaluated. The ratio of W/B 10%, Vs/Vm 20% and foaming agent 0.5% were selected as the basic mixing ratio for the mother panel of moss panel through pretest and SAP was added to improve the moisture content of panel. The optimal mixing ratio of SAP was considered to be less than 0.5% considering the quality characteristics. Also, through the use of alumina cement, the pH of the panel could be lowered to 10~11. The panel was able to improve the surface roughness through the foaming agent, and it was confirmed that the SAP had an effect of improving the moisture content of the panel. For the environmental impact characteristics of the moss panel, the moss panel evaluated the carbon dioxide reduction performance and the fine dust cleaning performance.

Does conventional freezing affect sperm DNA fragmentation?

  • Le, Minh Tam;Nguyen, Thai Thanh Thi;Nguyen, Tung Thanh;Nguyen, Trung Van;Nguyen, Tam An Thi;Nguyen, Quoc Huy Vu;Cao, Thanh Ngoc
    • Clinical and Experimental Reproductive Medicine
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    • v.46 no.2
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    • pp.67-75
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    • 2019
  • Objective: Sperm cryopreservation has been widely used in assisted reproductive technology, as it offers great potential for the treatment of some types of male infertility. However, cryopreservation may result in changes in membrane lipid composition and acrosome status, as well as reductions in sperm motility and viability. This study aimed to evaluate sperm DNA fragmentation damage caused by conventional freezing using the sperm chromatin dispersion test. Methods: In total, 120 fresh human semen samples were frozen by conventional methods, using SpermFreeze Solution as a cryoprotectant. Routine semen analysis and a Halosperm test (using the Halosperm kit) were performed on each sample before freezing and after thawing. Semen parameters and sperm DNA fragmentation were compared between these groups. Results: There was a significant decrease in sperm progressive motility, viability, and normal morphology after conventional freezing (32.78%, 79.58%, and 3.87% vs. 16%, 55.99%, and 2.55%, respectively). The sperm head, midpiece, and tail defect rate increased slightly after freezing. Furthermore, the DNA fragmentation index (DFI) was significantly higher after thawing than before freezing (19.21% prior to freezing vs. 22.23% after thawing). Significant increases in the DFI after cryopreservation were observed in samples with both normal and abnormal motility and morphology, as well as in those with normal viability. Conclusion: Conventional freezing seems to damage some sperm parameters, in particular causing a reduction in sperm DNA integrity.

Dioxygen Binding to Dirhodium(Ⅱ, Ⅱ), (Ⅱ, Ⅲ), and (Ⅲ, Ⅲ) Complexes. Spectroscopic Characterization of $[Rh_{2}(ap)_{4}(O_{2})]^{+},\;Rh_{2}(ap)_{4}(O_{2}),\;and\;[Rh_{2}(ap)_{4}(O_{2})]^-$, where ap=2-anilinopyridinate Ion

  • Lee, Jae-Duck;Yao, Chao-Liang;Capdevielle, Francoise J.;Han, Bao-Cheng;Bear, John L.;Kadish, Karl M.
    • Bulletin of the Korean Chemical Society
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    • v.14 no.2
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    • pp.195-200
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    • 1993
  • The neutral, reduced, and oxidized 2,2-trans isomers of $Rh_2(ap)_4$ (ap=2-anilinopyridinate) were investigated with respect to dioxygen binding in $CH_2Cl_2$ containing 0.1 M tetrabutyl-ammonium perchlorate. $Rh_2(ap)_4$ binds dioxygen in nonaqueous media and forms a $Rh^{II}Rh^{III}$ superoxide complex, $Rh_2(ap)_4(O_2)$. This neutral species was isolated and is characterized by UV-visible and IR spectroscopy, mass spectrometry and cyclic voltammetry. It can be reduced by one electron at $E_{1/2}$ = -0.45 V vs. SCE in $CH_2Cl_2$ and gives ${[Rh_2(ap)_4(O_2)]}^-$ as demonstrated by the ESR spectrum of a frozen solution taken after controlled potential reduction. The superoxide ion in ${[Rh_2(ap)_4(O_2)]}^-$ is axially bound to one of the two rhodium ions, both of which are in a +2 oxidation state. $Rh_2(ap)_4(O_2)$ can also be stepwise oxidized in two one-electron transfer steps at $E_{1/2}$ = 0.21 V and 0.85 V vs. SCE in $CH_2Cl_2$ and gives ${[Rh_2(ap)_4(O_2)]}^+$ followed by ${[Rh_2(ap)_4(O_2)]}^{2+}$. ESR spectra demonstrate that the singly oxidized complex is best described as ${[Rh^{II}Rh^{III}(ap)_4(O_2)]}^+$ where the odd electron is delocalized on both of the two rhodium ions and the axial ligand is molecular oxygen.