• The Korean Journal of Nuclear Medicine Technology
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• v.16 no.2
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• pp.29-34
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• 2012

Purpose : Presently, hardwares and softwares for reducing radiation exposure are continually developed for PET/CT examination. Purpose of this study is to evaluate effectiveness of reducing radiation exposure dose of CT and SUV changes of PET when applied each kernel to ACCT (Attenuation Correction Computed Tomography) according to adopted IRIS (Iterative Reconstruction in Image Space) software. Materials and Methods : Biograph mCT (Siemens, Germany) was used as a PET/CT scanner. Using AAPM CT performance phantom, from standard (120 kVp, 100 mAs), 7 scans were conducted by reducing 15 mAs each. After image reconstruction by FBP (Filtered Back Projection) and IRIS, noise and spatial resolution were evaluated. The same method was applied to anthropomorphic chest phantom and acquired images were compared. NEMA IEC body phantom was used for SUV evaluation. Injected dose rate for hot sphere (hot) and background cylinder (BKG) were 1:8. CT dose condition (120 kVp, 50 mAs) was the same for each scan and PET scan durations were 1, 2, 3 and 4min. After scanning, each kernel of IRIS was applied to ACCT. And PET images were reconstructed by ACCT adopted IRIS for comparing SUV changes. Results : AAPM phantom test for noise evaluation, SD for FBP 100 mAs, IRIS 55 mAs were 8.8 and 8.9. FBP 85 mAs, IRIS 40 mAs were 9.5 and 9.7. FBP 70 mAs, IRIS 25 mAs were 11.9 and 11.1. Above mAs condition for FBP and IRIS, SD showed similar values. And for spatial resolution test, there was no significant difference. For chest phantom test, when applied the same mAs and kernel to both of FBP and IRIS, every applied kernels showed reduced noise. Lower mAs and higher kernel value showed higher noise reduction. There was no considerable difference only except for I70 very sharp kernel for SUV comparison using NEMA IEC body phantom. Conclusion : In this study, low mAs (55 mAs) applied IRIS and standard mAs (100 mAs) applied FBP showed similar noise. And only except for I70 kernel, there was no significant SUV changes. It is possible to reduce needless radiation exposure and acquire better image quality than FBP's through applying appropriate kernel of IRIS to PET/CT.

• Korean Journal of Veterinary Research
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• v.36 no.2
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• pp.395-403
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• 1996

Monoclonal antibodies(MAbs) against field isolates of the bovine rotavirus A strain(G6), V strain(G10) and reference I-801 strain(G8) were produced and characterized. Six MAbs(4C2, 4D9, 5E1, 5E7, 5D5, 3E4) against A strain had neutralizing activity and reacted only with the G6 bovine rotaviruses determined by fluorescence focus neutralization (FFN) test. Otherwise, five neutralizing MAbs(1G2, 2G6, 5E2, 5E12, 5H7) against I-801 strain neutralized the G6 and G8 bovine rotaviruses. Five non-neutralizing MAbs(5F12, 7F12, 5E11, 2A11, 2B12) were VP6-specific and cross-reacted with all bovine and porcine rotaviruses examined by fluorescence antibody(FA) test. None of the MAbs reacted with bovie viral diarrhea virus(BVDV) and bovine coronavirus(BCV) determined by FA and FFN test.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.22
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• pp.9823-9829
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• 2014

Background: High-dose methotrexate (HD-MTX) is recognized as an efficient component of therapy against pediatric osteosarcoma in combination with other drugs such as cisplatin (CDP), carboplatin (CBDCA), doxorubicin (ADM), etoposide (VP-16) and ifosfamide (IFO). Objectives: To demonstrate the feasibility and effectiveness of the HD-MTX/CDP/DOX/VP-16/IFO [MTX(+)] protocol comparable to CDP/ADM/CBDCA/IFO [MTX(-)] for treating childhood osteosarcoma at Ramathibodi Hospital (1999-2014). Materials and Methods: A retrospective analysis was conducted of osteosarcoma patients aged less than 18 years treated with two chemotherapeutic regimens between 1999 and 2014. A total of 45 patients received the MTX(-) and 21 the MTX(+) protocol. Results: Overall limb-salvage and amputation rate were 12.9% and 77.7%, respectively. Kaplan-Meier analysis results for 3-year disease free survival (DFS) and overall survival (OS) regardless of treatment regimens were $43.4{\pm}6.0%$ and $53.2{\pm}6.1%$ respectively. The 3-year DFS and OS were improved significantly with the MTX(+) protocol compared to MTX(-) protocol (p=0.010 and p=0.009, log rank test) [$69.8{\pm}10.5%$, $79.8{\pm}9.1%$ for MTX(+) and $31.1{\pm}6.9%$, $42.2{\pm}7.4%$ for MTX(-) protocol, respectively]. Patients with metastatic osteosarcoma treated with the MTX(+) protocol had statistically significant higher 3-year DFS and OS than those treated with the MTX(-) protocol ($66.7{\pm}13.6%$ and $15.0{\pm}8.0%$ for 3-year DFS, p=0.010, $73.3{\pm}13.2%$ and $20{\pm}8.9%$ for 3-year OS, p=0.006, respectively). The independent risk factors for having inferior 3-year DFS and OS were poor histological response (tumor necrosis <90%) and treatment with the MTX(-) protocol. The multivariate analysis identified only the treatment with the MTX(-) protocol as an independent predictor of inferior OS with a hazard ratio (HR) of 3.53 (95% confidence interval of 1.2-10.41, p=0.022). Conclusions: Our study demonstrated the tolerability, feasibility and efficacy of the HDMTX-based regimen improving the survival rate in pediatric osteosarcoma cases, in line with reports from developed countries.

• The Optical Journal
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• s.113
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• pp.44-47
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• 2008

상업용 디지털 인쇄시장이 기존 복사기업계의 새로운 블루오션으로 부상하고 있다. 디지털 인쇄 시장에 가장 먼저 진출한 한국후지제록스는 최근 분당 288매 양면출력이 가능한 디지털 흑백 인쇄 시스템 '누베라288'을 출시하며 강한 자신감을 보이고 있는 가운데, 지난해 7월 옵셋 인쇄기와 동등한 품질의 디지털 인쇄기 'IPRC7000VP'를 선보이며 캐논코리아비즈니스솔루션이 후발주자로 추격을 시작한데 이어 11월에는 신도리코가 코닥과 손잡고 컬러.흑백 디지털 인쇄기 '넥스프레스.디지마스터'를 선보이며 시장에 합류했다. 디지털 상업 인쇄시장은 전 세계적으로 연간 30%의 성장률을 보이고 있는 유망 성장 시장으로서 통합문서관리 시장과 함께 복사기 및 프린팅 업체들이 차세대 수익창출원으로서 경쟁적인 마케팅을 펼칠 것으로 보인다.

• Journal of the Korean Institute of Telematics and Electronics B
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• v.33B no.4
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• pp.217-225
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• 1996

This paper describes a high power resonant inverter for diagnostic X-ray generators using zero-voltage soft-switching technology. The system consists of a step-down chopper, a resonant phase-shift PWM inverter, a hihg-voltage diode, and high voltage cables a smoothing DC capacitor. The inverter makes use the leakage inductance of the hihg-voltage transformer and external capacitor as resonant components. The rectified input voltage is controlled by a step-down chopper with input voltage compensator. The output regualtion is obtained by a resonant phase-shift PWM inverter with the digital feedback controller using DSP (digital signal processor), resulting in fast rising time and wide output voltage variation. The theoretical results are correlated with results from an experimental prototype of a 7-kVp, 300mA (21kW).

• Journal of radiological science and technology
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• v.24 no.1
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• pp.17-22
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• 2001

Medical X-ray examination are increased double for the last $6{\sim}8$ years. Therefore a patient exposure dose should be decrease half every 7 years. We made an experiment on copper filter thickness to decrease a patient exposure dose up to half and compared to the Image quality by MTF. The results as follow 1. A thin region like extremities needs a thicker Cu filter as compared a thick region. 2. 1/2 reduction filter must be thicker when kVp Increase. 3. Exposure factor should be increas when using 1/2 reduction filter ; extremity is 4.0 times, chest 2.9 times, skull 1.62 times, and abdomen 1.58 times 4. The MTF of using 1/2 reduction filter is lower than without filter. But no difference of visual image. 5. 1/2 reduction filter compared with double speed screen showed almost same image quality.

• Journal of the Korean Institute of Telematics and Electronics A
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• v.31A no.12
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• pp.16-22
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• 1994

In this paper, transmitter and receiver modules for free space optical interconnection are implemented and characterized. In the transmitter module, bias circuitry which inject current into the direct modulated laser diode is fabricated and in the receiver module, p-i-n diode is integrated with an MMIC amplifying stage. Laser diode has a direct-modulated bandwidth of 2 GHz at 1.4 Ith bias while p-i-n diode and amplifying stage has a bandwidth of 1.3 GHz and 1.5 GHz, repectively. Optical interconnection has a bandwidth of 1.3 GHz and linearly transmit modulated voltage signal up to 1.5 Vp-p. Measured loss of optical interconnection is 5dB which is composed of optoelectronic conversion loss of 15 dB, electrical impedance mismatch loss of 6.7 dB in transmitter module and gain of 18 dB in receiver module. Seperation between transmitter and receiver can be extended up to 50 cm by using a lens.

• Nuclear Engineering and Technology
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• v.34 no.3
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• pp.211-217
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• 2002

A 1-MW vacuum feedthrough for the KSTAR ICRF antenna is fabricated and high power RF test is performed. It is designed to have two alumina $(Al_2O_3)$ ceramic cylinders and O-ring seal instead of a brazed seal for good mechanical and thermal strength, which is important in long pulse or steady state operation. For cooling of the ceramics, dry air is circulated in a space between the two cylinders and the outer conductor. Independent cooling water channels are installed to cool the inner conductor of the feedthrough. RF high voltage test is performed using two kinds of ceramics with the purities of 99.7% and 97%. Stable operation is possible with the RF voltage of 30 kVp at long pulse of 300 sec without any severe damage.

• Journal of the Korean Society of Clothing and Textiles
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• v.26 no.7
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• pp.970-981
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• 2002

The purpose of the study is to clarify orange image in the modern fashion. So kinds of costume sample being visual power in orange have been selected from photographs in fashion magazines and divided into the tones : mist(Vp, Lgr, L), bright(P, B), vivid(S, V, Dp). The study was measured by using 27 semantic differential hi-polar scales. The subjects were 50 female students majoring in clothing and textiles, The data was analyzed using the statistical SPSS package. The data were collected using self-administred questionnaires and analyzed by Cronbach $\alpha$, Factor analysis, MDS, ANOVA Sheff test and Regression analysis. The major findings of this research were as follows. 1. Factor analysis has extracted 4 factors of orange image in the fashion. These factor are Attractiveness, Audacity, Hardness and Softness, Cuteness. 2. There were significant difference in visual evaluation of tones. 3. The discrimination among tones was related to cuteness and weight of orange. 4. The image effect on Preference, Buying needs, Pleasant and Riches was consist of complicated sensibility.

• Journal of Veterinary Science
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• v.24 no.2
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• pp.18.1-18.7
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• 2023

Tibet orbivirus (TIBOV) was identified as a novel orbivirus in 2014. Antibodies against TIBOV were detected in cattle, Asian buffalo, and goats, while all the sequenced TIBOV strains were isolated from mosquitos and Culicoides. The known TIBOV strains have been classified into four putative serotypes. In this study, two TIBOV strains isolated from Culicoides spp. in Shizong County of Yunnan Province, China, were fully sequenced. The phylogenetic analysis of outer capsid protein 2 (VP2) indicated that these two viral strains belong to two novel putative serotypes of TIBOV. The updated putative serotypes may help in an investigation of the distribution and virulence of TIBOV.