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Discrimination of Postradiotherapy Lung Fibrosis from Recurrence by Gallium-67 Scan in Lung Cancer (갈륨 스캔을 이용한 폐암의 치료 후 섬유성 변성과 재발의 감별)

  • Ryu, Sam-Uel;Lee, Jae-Tae
    • Radiation Oncology Journal
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    • v.9 no.1
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    • pp.81-85
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    • 1991
  • The differentiation between post-radiotherapy lung fibrosis and tumor recurrence is often a dilemma to physicians. Twenty two patients with lung cancer who had received 45~60 Gy to the chest were chosen to study the possible role of gallium-67 scan. Seventeen squamous cell carcinomas were treated with only radiotherapy, 3 small cell carcinomas with combination chemotherapy, 2 adenocarcinomas with lobectomy. A total of 8 patients with pneumonitis with or without fibrosis and recurrence showed uptake of gallium at the site of inflammation. Of the 12 recurrences and residual diseases after radiotherapy, positive gallium uptake was present in 11 cases (92%). Of the 10 recurrence-free cases, all the 5 patients with pneumonitis revealed gallium accumulation. However, 4 of the 5 patients (80%) with recurrence-free fibrosis have not accumulated gallium in the fibrotic areas. Fibroses in S patients were developed after 8 months of completion of radiotherapy. These facts suggest that gallium-67 scan after 1 year post-treatment may aid for the discrimination of fibrosis from tumor recurrence unless pneumonitis is present.

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Construction and Performance Evaluation of Digital Radiographic System (이동형 디지털 X선 촬영장치의 구축 및 성능평가)

  • Cho, Hyo-Min;Nam, So-Ra;Lee, Chang-Lae;Jung, Ji-Young;Kim, Hee-Joung
    • Progress in Medical Physics
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    • v.18 no.3
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    • pp.144-148
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    • 2007
  • Current digital radiography systems are rapidly glowing in clinical applications. The purpose of this study was to evaluate the characteristics of a mobile digital radiographic system. The performance of the mobile DR system was evaluated by measuring the modulation transfer function (MTF), noise power spectrum (NPS), and detective quantum efficiency (DQE). Measurements were made on a LISTEM Mobix-1000 generator and a Teleoptic PRA Alpha-R4000 detector. Imaging characteristics were measured for these two systems using the IEC-61267 defined RQA5 (kVp: 74, additional filtration: 21 mmAl) radiographic condition. The MTF at 10% was measured as 2.4 cycles/mm and the DQE(0) values for radiation exposure 0.19, 0.5, and 1.3 mR were measured as 54%, 55%, and 76%, respectively. The NPS curves gradually decreased at high spatial frequencies. This high DQE at low frequencies, may be useful for low frequency information. The results suggested that mobile DR system could be integrated with emergency ambulance system in teleradiologic imaging applications.

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Quantitative Analysis of Bone Mineral Measurements in Different Types of Dual-energy Absorptiometry Systems: Comparison of CT vs DEXA (이중 에너지 조사 방식의 장비별 골밀도 측정의 정량적 비교 분석: CT vs DEXA 비교)

  • Kim, Myeong Seong
    • Journal of radiological science and technology
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    • v.40 no.2
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    • pp.311-316
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    • 2017
  • Generally assessing bone mineral density (BMD) were performed on dual energy X-ray absorptiometry (DEXA) the same as dual energy CT (DECT) with a rapid-kVp switching. The purpose of this study is to compare the different of BMD value between DEXA and DECT method, and evaluate usefulness of DECT method. Using scanner for BMD measurements were GE, Healthcare Discovery 750 HD for DECT and Hologic QDR 4500W for DEXA. For compare BMD value in each method, scanned lumbar spine phantom and subjects visiting Korean National Cancer Center from April 2015 to December 2015, records of 50 patients. This study was approved by the Institutional Review Board. The mean BMD value measures for spine phantom and for subjects in each scanners presented strong correlation (r=0.948 with p<0.05 for phantom; r=0.635 with p<0.05 and Kendall's tau $({\tau})=0.46$ with p<0.05 for subjects) and linear relationship between DECT and conventional DEXA. DECT technique for BMD measurement will provide a very useful methodology without additional radiation dose.

Replacement value of cassava for maize in broiler chicken diets supplemented with enzymes

  • Chang'a, Edwin Peter;Abdallh, Medani Eldow;Ahiwe, Emmanuel Uchenna;Mbaga, Said;Zhu, Ze Yuan;Fru-Nji, Fidelis;Iji, Paul Ade
    • Asian-Australasian Journal of Animal Sciences
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    • v.33 no.7
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    • pp.1126-1137
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    • 2020
  • Objective: Pellet durability, particle size distribution, growth response, tibia bone characteristics and energy retention were measured to evaluate cassava as an alternative energy source to replace maize in broiler diets with or without Ronozyme (A+VP) enzyme composites. Methods: A total of 480 one-day broiler chicks were randomly assigned to 8 treatments in a 4×2 factorial arrangement. Four levels of cassava: (0%, 25%, 50%, 75%) and 2 levels of enzymes (0 and 500 g/tonne) were used. Each treatment was replicated six times, with ten birds per replicate. Results: The particle size distribution in the diets showed an increasing trend of small particles with increase in cassava level. Pellet durability decreased (p<0.05) with cassava inclusion. Feed intake was highest in birds fed diets with medium cassava level at 1 to 24 d and 1 to 35 d of age. The body weight gain of birds reduced (p<0.037) as cassava level increased, but it increased (p<0.017 when enzymes were added. The feed conversion ratio was high (p<0.05) when cassava level was increased, but it reduced (p<0.05) when enzymes were added. The dressing percentage (DP), and weight of drumsticks reduced (p<0.05) with increasing cassava level. Enzyme supplementation increased (p<0.05) DP, and weight of breast, thighs and drumsticks. Ash content, weight, length, width, and bone strength decreased (p<0.05) when cassava level was increased, however, they were increased with enzyme addition. The contents of Ca, K, and Zn were raised (p<0.001) with increasing cassava level. Enzyme inclusion increased (p<0.001) all mineral contents in tibia bones. Body fat and energy retained as fat decreased (p<0.001) as cassava level increased. Enzyme inclusion increased (p<0.05) body protein content and energy retained as protein. Conclusion: Although broiler performance was depressed by high levels of cassava inclusion, it was not affected by low levels, which further improved by enzyme supplementation.

Study on the Exposure Dose(mAs) and acquisition Image set up Density Display and Sensitivity of control Panel for the Digital Flat-Panel-Detector (디지털 평판형 검출기에서 Control Panel의 Density Display와 Sensitivity 설정이 조사선량(mAs)과 획득영상에 미치는 영향에 관한 연구)

  • Kim, Byung-Ki;Kim, Sang-Keun;Cha, Seon-Hwa;Choi, Jun-Gu;Lee, Jun;Kim, Min-Woo;Kim, Sun-Bae;Kim, Gyeong-Sun
    • Korean Journal of Digital Imaging in Medicine
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    • v.9 no.2
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    • pp.17-21
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    • 2007
  • The purpose to recognize change of average pixel value of acquisition image by control panel's density and right set up method of speed (sensitivity) and exposure dose(mAs) change that dose in purpose digital flatpanel-detector. X -ray generator DHF-158H2(Hitachi, Japan). Detector CXDI 4OG(Canon, Japan), 12 : 1 grid and exposure ray 135 kVp, 250 mA, 10 ms. focus-detector distance 180 cm and used AEC mode. DICOM reflex analysis program used image J that is digital reflex analysis program that offer in United States America National Health Center(National Institutes of Health : NlH) phantom used chest phantom(Anthromorphic : Flukebrome.medicaI USA). An experiment chest phantom that consist by formation equivalence material use because density value( -3${\sim}$+3) in X-ray control panel and seep that is speed step(slow, medium, fast) each control experimentalize. image analysis reflex neted through an experiment using image j each image compare. These was change in dose according to slow, medium, fast and density's change in an experiment result. According to detector sensitivity and density condition set, dose was relationship dissimilarity 500% from 200%. The dose came highest when is density +3 to slow. and dose more increases gray scale's extent could know that rise. Could know whether how equipment set is important through this experiment. cause of disease which change by digital radiography system forward is thought to increase more, it is considered that suitable education by this and continuous interest about equipment need absolutely.

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Study on Performance Evaluation of Dental X-ray Equipment (치과 방사선 발생기의 성능평가에 관한 연구)

  • Jung, Jae-Eun;Jung, Jae-Ho;Kang, Hee-Doo;Lee, Jong-Woong;Ra, Keuk-Hwan
    • Korean Journal of Digital Imaging in Medicine
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    • v.11 no.2
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    • pp.115-119
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    • 2009
  • I think this will be valuable reference for assuring consistency and homogeneity of clarity and managing dental radiation equipment by experimentation of dental radiation equipment permanent which based on KS C IEC 61223-3-4 standard and KS C IEC 61223-2-7. Put a dental radiation generator and experiment equipment as source and film(sensor) length within 30 em, place the step-wedge above the film(sensor). Tie up tube voltage 60 kVp, tube current 7 mA and then get an each image through CCD sensor and film by changing the exposure time as 0.12sec, 0.25sec, 0.4sec. Repeat the test 5times as a same method. Measure the concentration of each stage of film image, which gained by experiment, using photometer. And the image that gained by CCD sensor, analyze the pixel value's change by using image J, which is analyzing image program provided by NIH(National Institutes of Health). In case of film, while 0.12sec and 0.25sec show regular rising pattern of density gap as exposure time's increase, 0.4sec shows low rather than 0.12sec and 0.25sec. In case of CCD sensor density test, the result shows opposite pattern of film. This makes me think that pixels of CCD's sensor can have 0~255 value but it becomes saturation if the value is over 255. The way that getting clear reception during decreasing human's exposed radiation is one of maintaining an equipment as a best condition. So we should keeping a dental radiation equipment's condition steadily through cyclic permanent test after factor examination. Even digital equipment doesn't maintain a permanent, it can maintain a clarity by post processing of image so that hard to set it as standard of permanent test. Therefore it would be more increase the accuracy that compare a film as standard image. Thus I consider it will be an important measurement to care for dental radiation equipment and warrant homogeneity, consistency of dental image's clarity through comparing pattern which is the result from factor test against cyclic permanent test.

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Molecular Taxonomy based on 16S rDNA Analysis and Pathogenicity of Yersinia pseudotuberculosis Isolated from Spring Waters (약수에서 분리한 Yersinia pseudotuberculosis의 병원성과 16S rDNA 분석에 의한 분자학적 분류)

  • Lee, Young-Kee;Choi, Sung-Min;Oh, Soo-Kyung;Lee, Kang-Moon;Ryeom, Kon
    • Korean Journal of Microbiology
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    • v.37 no.1
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    • pp.9-14
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    • 2001
  • In order to investigate the pathogenicity and development of differential identification technique in the Yersinia species and other entericbacteria, we isolated 5 strains of Y.pseudotuberculosis from spring water sites in Seoul. The biochemical characteristics of isolated strains revealed that indole, VP($25^{\circ}C$, $37^{\circ}C$), $H_2S$, phenylalanine, lysine, arginine, ornithine, gas from glucose, lactose, sucrose, sorbitol, oxidase and motility($37^{\circ}C$) were all negative and urease, glucose, mannitol, salicin, catalase and motility($25^{\circ}C$) were all positive. To detect the causative agent of pseudotuberculosis(Y.pseudotuberculosis), we carried out a study using a PCR with inv primers complementary to the pathogenic region and found that all strains were positive, this revealed that strains from spring waters were pathogenic. Also 16S rDNA for total 5 strains of Y. pseudotuberculosis were amplified and a stretch of approximately 1,450 nucleotides were sequenced and analyzed. The 16S rDNA nucleotide sequence homologies among Yersinia species ranged 97.5% to 100% and between Y.pseudotuberculosis and other entericbacteria they ranged 93.0% to 95.1%. The Phylogenetic tree generated from the sequence analysis of the 16S rDNA gene showed 3 coherent clusters that could be separated into Y.pseudotuberculsis strains, some Yersinia species strains and other entericbacteria strains.

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Selection of mAs with Using Table Strap in Computed Tomography Scan (전산화단층촬영 시 환자 고정 밴드를 이용한 선량의 선택)

  • Lee, Young-Hyen;An, Hyeong-Theck
    • Korean Journal of Digital Imaging in Medicine
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    • v.13 no.2
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    • pp.63-69
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    • 2011
  • Table strapis patient fixture for securing the patient movements and falls. if it designed to measure the abdominal circumference and used as an indicator of dose selection at CT scan. it will prevent the overexposure of dose without degradation of image quality and efficiently manage dose of each type of body to technician to deal with CT. First, in order to compare the dose used in CT image and qualitative characteristics. reference image is obtained by examining the abdominal phantom in same conditions with the hospital 120 kVp, 200 mAs, D-Dom (Dynamic Dose Of Modulation). SNR, PSNR, RMSE, MAE, CTDIvol of CT images are compared with reference image. for comparing with reference image, the image that Umbilicus level image of Abdomen CT is stored in the PACS were used. For comparison, the top 12 o'clock portion of the air drawn from the same ROI was measured. CTDIvol, mAs, etc. In order to analyze the characteristics of the image, by measuring the length of the umbilicus circumference, pattern of the dose was analyzed. by using the analyzed perimeter and dose information, To be identified visually, fixed band that scale marked were produced. Use them, If the length of circumference of less than 60 cm 100 mAs, Case of 61~80 cm 120 mAs, Case of 80~100 cm 150 mAs, more than 100 cm 200 mAs, dose selection based on the perimeter, the image was applied. by compare analyzed with the Reference Image, image quality was assessed. by compare with existing tests that equally 200 mAs applied, How much was confirmed that the dose reduction. 1. Depending on the Abdominal circumference, the average PSNR(dB) of the image that differently dose applied was 45.794. 2. Comparing with existing test. the dose of scan that adjusted the mAs depending on the circumference was decreased about 40%. SNR and PSNR of the image that obtained by adjusting the standard mAs based on dose modulation were not much different. Therefore, By choosing a low mAs. dose reduction can be obtained. and the dose selection method that measured Abdominal circumference using a fixed band can protect the overexposure and uniformly apply dose of each type of body to technician to deal with CT.

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Studies on the Frost Heave Revelation and Deformation Behaviour due to Thawing of Weathered Granite Soils (화강암 풍화토의 동상 발현 및 융해에 따른 변형 거동에 관한 연구)

  • 류능환;최중대;류영선
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.37 no.3_4
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    • pp.61-71
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    • 1995
  • Natural ground is a composite consisted of the three phases of water, air and soil paircies. Among the three components, water as a material is weU understood but soil particles are not in foundation engineering. Especially, weathered granite soil generally shows a large volumetric expansion when they freeze. And, the stability and durability of the soil have shown decreased with repetitive freezing and thawing processes. These unique charcteristics may cause various construction and management problems if the soil is used as a construction material and foundation layers. This project was initiated to investigate the soil's physical and engineering characteristics resulting from freezing and freezing-thawing processes. Research results may be used as a basic data in solving various problems related to the soil's unique characteristics. The following conclusions were obtained: The degree of decomposition of weathered granite soil in Kangwon-do was very different between the West and East sides of the divide of the Dae-Kwan Ryung. Soil particles distributed wide from very coarse to fine particles. Consistency could be predicted with a function of P200 as LL=0.8 P200+20. Permeability ranged from 10-2 to 10-4cm/sec, moisture content from 15 to 20% and maximum dry density from 1.55 to 1.73 g /cmΥ$^3$ By compaction, soil particles easily crushed, D50 of soil particles decreased and specific surface significantly increased. Shear characteristics varied wide depending on the disturbance of soil. Strain characteristics influenced the soil's dynamic behviour. Elastic failure mode was observed if strain was less than 1O-4/s and plastic failure mode was observed if strain was more than 10-2/s. The elastic wave velocity in the soil rapidly increased if dry density became larger than 1.5 g /cm$^3$ and these values were Vp=250, Vg= 150, respectively. Frost heave ratio was the highest around 0 $^{\circ}C$ and the maximum frost heave pressure was observed when deformation ratio was less than 10% which was the stability state of soil freezing. The state had no relation with frost depth. Over freezing process was observed when drainage or suction freezing process was undergone. Drainage freezing process was observed if freezing velocity was high under confined pressure and suction frost process was occurred if the velocity was low under the same confined process.

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Controll over the Au@Ag Core-shell Nanoparticle 2D Patterns via Diblock Copolymer Inverse Micelle Templates and Investigation of the Surface Plasmon Based Optical Property (이중블록공중합체 역마이셀 주형을 이용한 Au@Ag 코어-쉘 나노입자 2차원 패턴 제어 및 표면 플라즈몬 기반 광학적 특성 연구)

  • Yoon, Min Ji;Kim, Jihyeon;Jang, Yoon Hee;Lee, Ji-Eun;Chung, Kyungwha;Quan, Li Na;Kim, Dong Ha
    • Journal of the Korean Chemical Society
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    • v.57 no.5
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    • pp.618-624
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    • 2013
  • We demonstrated unique inter- and intra-plasmonic coupling effects in bimetallic Au@Ag core-shell NP arrays which are regularly or randomly arranged on self-assembled block copolymer (BCP) inverse micelle monolayers. Polyvinylpyrrolidone (PVP)-stabilized Au@Ag core-shell NP arrays in regular or disordered configuration were incorporated and assembled on reconstructed PS-b-P4VP inverse micelle templates through two types of processes. The intensively enhanced LSPR coupling properties of individual and assembled Au@Ag NPs were evaluated by UV-visible spectroscopy in terms of the type of ligand stabilizer, coupling between Au and Ag, thickness of Ag shell, and type of array configuration. Finally, Au@Ag core-shell NP arrays were employed as active substrates for surface enhanced Raman spectroscopy (SERS) and a significantly enhanced signal enhancement was observed in accordance with the coupling intensity of Au@Ag NPs patterns.