• Proceedings of the Korea Information Processing Society Conference
• /
• 2011.11a
• /
• pp.1555-1558
• /
• 2011

국방 모델링 및 시뮬레이션(Modeling & Simulation) 소프트웨어 분야에서 분산 시뮬레이션 기술표준인 HLA(High Level Architecture)의 적용이 늘어나고 있으며, 시뮬레이션 요소의 재사용성 및 신뢰성 확보를 위한 개발 프레임워크 제공이 핵심기술로 떠오르고 있다. 특히, 시뮬레이션을 위한 공통 서비스를 제공하는 M&S 프레임워크가 개발되었다. 또한, 가상의 시험 환경을 제공하기 위한 요소 중 시험환경의 구성을 위한 시나리오 모델이 있다. 본 논문에서는 시험 환경을 구성하기 위한 M&S 프레임워크 내의 시나리오의 스키마 설계에 대해서 기술한다.

• Journal of the Korean Applied Science and Technology
• /
• v.28 no.1
• /
• pp.75-84
• /
• 2011

Atopic dermatitis is a chronic inflammatory skin disease associated with cutaneous hyper-reactivity to environmental triggers. In order to develop effective therapeutic herbal extracts for atopic dermatitis, cytotoxicity, antioxidant, anti-inflammatory and anti-allergic activities were investigated for various herbal extracts. Among candidate extracts, we selected Aloe vera L. (AV), Viola mandshurica W. Becker (VM), Punica granatum L. (PG), Dendrobium nobile L. (DN) and mixture of the above extracts (MX) for further investigations. All of them did not show cytotoxic activities to macrophage RAW264.7 cells below the concentration of 100 ppm. All showed antioxidant, anti-inflammatory and anti-allergic effects, although to various extents. In antioxidant effects, AV showed the highest effect, followed by PG and VM, while DN did the lowest. In evaluation for anti-inflammatory activities in macrophage RAW264.7 cells, AV and DN inhibited almost completely the LPS-induced production of nitric oxide, while AV, DN and VM showed strong inhibitory activities on the LPS-induced production of TNF-${\alpha}$. In anti-allergy effect in mast cell HMC-1, DN showed the highest effect, followed by AV and PG, while VM did the lowest. In the topical allergy reaction induced by compound 48/80 in Sprague-Dawley rat, DN exhibited significant anti-allergic effect, while PG, VM and AV did slight effect. These results suggest that AV, VM, PG and DN have antioxidant, anti-inflammatory and anti-allergic activities, and thus have the potential to reduce and alleviate the symptoms of atopic dermatitis.

• BMB Reports
• /
• v.53 no.6
• /
• pp.291-298
• /
• 2020

Tumor angiogenesis is an essential process for growth and metastasis of cancer cells as it supplies tumors with oxygen and nutrients. During tumor angiogenesis, many pro-angiogenic factors are secreted by tumor cells to induce their own vascularization via activation of pre-existing host endothelium. However, accumulating evidence suggests that vasculogenic mimicry (VM) is a key alternative mechanism for tumor vascularization when tumors are faced with insufficient supply of oxygen and nutrients. VM is a tumor vascularization mechanism in which tumors create a blood supply system, in contrast to tumor angiogenesis mechanisms that depend on pre-existing host endothelium. VM is closely associated with tumor progression and poor prognosis in many cancers. Therefore, inhibition of VM may be a promising therapeutic strategy and may overcome the limitations of anti-angiogenesis therapy for cancer patients. In this review, we provide an overview of the current anti-angiogenic therapies for ovarian cancer and the current state of knowledge regarding the links between microRNAs and the VM process, with a focus on the mechanism that regulates associated signaling pathways in ovarian cancer. Moreover, we discuss the potential for VM as a therapeutic strategy against ovarian cancer.

• Proceedings of the Korean Vacuum Society Conference
• /
• 2010.02a
• /
• pp.464-464
• /
• 2010

A few years ago, for maintaining high stability and production yield of production equipment in a semiconductor fab, on-line monitoring of wafers is required, so that semiconductor manufacturers are investigating a software based process controlling scheme known as virtual metrology (VM). As semiconductor technology develops, the cost of fabrication tool/facility has reached its budget limit, and reducing metrology cost can obviously help to keep semiconductor manufacturing cost. By virtue of prediction, VM enables wafer-level control (or even down to site level), reduces within-lot variability, and increases process capability, $C_{pk}$. In this research, we have practiced VM on $SiO_2$ etch rate with optical emission spectroscopy(OES) data acquired in-situ while the process parameters are simultaneously correlated. To build process model of $SiO_2$ via, we first performed a series of etch runs according to the statistically designed experiment, called design of experiments (DOE). OES data are automatically logged with etch rate, and some OES spectra that correlated with $SiO_2$ etch rate is selected. Once the feature of OES data is selected, the preprocessed OES spectra is then used for in-situ sensor based VM modeling. ICP-RIE using 葰.56MHz, manufactured by Plasmart, Ltd. is employed in this experiment, and single fiber-optic attached for in-situ OES data acquisition. Before applying statistical feature selection, empirical feature selection of OES data is initially performed in order not to fall in a statistical misleading, which causes from random noise or large variation of insignificantly correlated responses with process itself. The accuracy of the proposed VM is still need to be developed in order to successfully replace the existing metrology, but it is no doubt that VM can support engineering decision of "go or not go" in the consecutive processing step.

• Journal of International Academy of Physical Therapy Research
• /
• v.10 no.2
• /
• pp.1768-1773
• /
• 2019

Background: Aging reduces cognitive abilities, including visual memory (VM) and visual discrimination (VD). Since common cortical networks subserve eye movement and attention, voluntary eye movement may improve visual attention. Visual selective attention was major role for memory, and visual memory and visual attention are intimately related. Objective: To identify the improvement in VD and VM, after implementing the eye movement program consisting of saccadic eye movement (SEM) and pursuit eye movement (PEM) in the institutionalized healthy elderly. Design: Randomized controlled trial. Methods: The study involved a sample of 36 participants, and the mean age was 79.03 years (range 76~84 years). They were randomly allocated to the experimental group (n=16) and control group (n=20). Participants in the experimental group performed SEM 5 times per week for 4 weeks: twice daily at the same time in the morning and afternoon. The program was carried out for 3 minutes, and it consisted of SEM and PEM. The target's moving frequency was set at 0.5 Hz. VM and VD at the baseline and post-intervention were measured using Motor-Free Visual Perception test-4 (MFVPT-4). Results: VM significantly improved in the experimental group (p < .01), and significant differences were observed compared to the control group (p < .01). There was no significant change in VD. Conclusion: The eye movement program consisting of SEM and PEM increased VM more than VD. Therefore, eye movement program was feasible interventions for improving VM in institutionalized elderly persons.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.26 no.6D
• /
• pp.927-933
• /
• 2006

The Variable Message Signs (VMS) are useful way to reduce the socio-economic costs due to the traffic congestions and delays by providing the information on traffic condition to drivers. This study provided a methodology to determine the locations of VMS's in terms of the minimization of the delay by applying the genetic algorithm. The optimal number of VMS's was also derived by the economic analysis based on the cost and the benefit. The simulation considered the variation of traffic volume, the frequency and duration of the incident, and the traffic conversion in order to reflect the real situation. I've made a scenario to consider traffic volume and incident, and it can undergo through changing different traffic volume and incident in time and days and seasons. And I've comprised two kinds of result, one is based on empirical studies, the other is based on Genetic Algorithm about optimal allocation VMS. This result of using optimal location VMS, reduce total travel time rather than preceding study based on normal location VMS and we can estimate optimal location VMS each one.

• Korean Journal of Optics and Photonics
• /
• v.13 no.1
• /
• pp.51-57
• /
• 2002

We have calculated the optimum refractive index and normalized thickness of a single layer antireflection coating on the facet of buried channel waveguides as a function of waveguide width for several waveguide depths using the angular spectrum method and field profiles obtained by the effective index method (EIM) and the variational method (VM), respectively, and discussed the results. In the area of large waveguide width, the optimum parameters of a single layer antireflection coating obtained by both methods are almost the same. However, as waveguide width decreases, the parameters obtained by the VM approach those of a single layer antireflection coating between cladding layer and air, while those obtained by the EIM do not approach those, and the difference between the two parameters is large. The tolerance maps of the quasi-TE and quasi-TM modes obtained by the VM for square waveguides are located in almost the same area regardless of refractive index contrast, while those obtained by the free space radiation mode (FSRM) method for refractive index contrast of 10% are located in the different area. Thus, we think that the tolerance maps obtained by the VM are more exact than those obtained by the FSRM method.

• The KIPS Transactions:PartB
• /
• v.18B no.5
• /
• pp.249-254
• /
• 2011

FGS (fine granularity scalability) supporting scalability in MPEG-4 Part 2 is a scalable video coding scheme that provides bit-rate adaptation to varying network bandwidth thereby achieving of its optimal video quality. In this paper, we proposed FGS coding scheme which performs one more bit-plane coding for residue signal occured in the enhancement-layer of the basic FGS coding scheme. The experiment evaluated in terms of video quality scalability of the proposed FGS coding scheme by comparing with FGS coding scheme of the MPEG-4 verification model (VM-FGS). The comparison was conducted by analysis of PSNR values of three tested video sequences. The results showed that when using rate control algorithm VM5+, the proposed FGS coding scheme obtained Y, U, V PSNR of 0.4 dB, 9.4 dB, 9 dB averagely higher and when using fixed QP value 17, obtained Y, U, V PSNR of 4.61 dB, 20.21 dB, 16.56 dB averagely higher than the existing VM-FGS. From results, we found that the proposed FGS coding scheme has higher video quality scalability to be able to achieve video quality from minimum to maximum than VM-FGS.

• Journal of KIISE:Computer Systems and Theory
• /
• v.37 no.3
• /
• pp.172-183
• /
• 2010

Virtual memory systems (VM) reduce disk I/Os caused by page faults using page prefetching, which reads pages together with a desired page at a page fault in a single disk I/O. Operating systems including 4.4BSD attempt to prefetch as many pages as possible at a page fault regardless of page access patterns of applications. However, such an approach increases a disk access time taken to service a page fault when a high portion of the prefetched pages is not referenced. More seriously, the approach can cause the memory pollution, a problem that prefetched pages not to be accessed evict another pages that will be referenced soon. To solve these problems, we propose an adaptive page prefetching control scheme (APC), which periodically monitors access patterns of prefetched pages in a process unit. Such a pattern is represented as the ratio of referenced pages among prefetched ones before they are evicted from memory. Then APC uses the ratio to adjust the number of pages that 4.4BSD VM intends to prefetch at a page fault. Thus APC allows 4.4BSD VM to prefetch a proper number of pages to have a better effect on reducing disk I/Os, though page access patterns of an application vary in runtime. The experiment of our technique implemented in FreeBSD 6.2 shows that APC improves the execution times of SOR, SMM, and FFT benchmarks over 4.4BSD VM by up to 57%.

• Journal of the Institute of Electronics Engineers of Korea SC
• /
• v.42 no.1
• /
• pp.1-11
• /
• 2005

Several Solid Freeform Fabrication Systems(SFFS) are commercialized in a few companies for rapid prototyping. However, they have many technical problems including the limitation of applicable materials. A new method of agile prototyping is required for the recent manufacturing environments of multi-item and small quantity production. The objectives of this paper include the development of a novel method of SFFS, the CAFL/sup VM/(Computer Aided Fabrication of Lamination for Various Material), and the manufacture of the various material samples for the certification of the proposed system and the creation of new application areas. For these objectives, the technologies for a highly accurate robot path control, the optimization of support structure, CAD modeling, adaptive slicing was implemented. However, there is an important problem with the conventional 2D lamination method. That is the inaccuracy of 3D model surface, which is caused by the stair-type surface generated in virtue of vertical 2D cutting. In this paper, We design the new control algorithm that guarantees the constant speed, precise positioning and tangential cutting on the 5DOF SFFS. We develop the tangential cutting algorithm to be controlled with constant speed and successfully implemented in the 5DOF CAFL/sup VM/ system developed in this paper. Finally, this paper confirms its high-performance through the experimental results from the application into CAFL/sup VM/ system.