• Journal of the Institute of Electronics Engineers of Korea SD
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• v.44 no.8
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• pp.74-79
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• 2007

In general, the high cost, long time, and complex steps are required in the design and implementation of MPSoC(Multi-Processor System on a Chip), therefore a platform is used to test the functionality and performance of IPs(Intellectual Properties). In this paper, we study a platform architecture to verify IPs based on Interconnect Network among processors, and show that the MPSoC platform gives better performance than a single processor for an application program.

• Journal of the Microelectronics and Packaging Society
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• v.27 no.3
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• pp.1-8
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• 2020

In this paper, the principles, characteristics and recent studies of the laser micro soldering are reviewed. The factors which influence laser micro welding and soldering are also included. Laser soldering is a non-contact process that transfers energy to solder joint by a precisely controlled laser beam. In recent electronics industry, the demands for laser soldering are increasing due to bonding for complex circuits and local heating in micro-joint. In laser soldering, there are several important factors like laser absorption, laser power, laser scanning speed, and etc, which affect laser solderability. The laser absorption ratio depends on materials, and each material has different absorption or reflectivity for the laser beam, which requires fine adjustment of the laser beam. Laser types and operating conditions are also important factors for laser soldering performance, and these are also reviewed.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.43 no.11 s.353
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• pp.19-25
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• 2006

The fast processing ability of an RTOS (Real Time Operating System) is one of important factors in determining the performance of embedded systems. With the development of multimedia and telecommunication technology, the higher level of performance environments is required. Moreover there is some difficulty in improving the performance of an RTOS which is based on a microprocessor. In this paper, we propose a hardware architecture to implement some functions of uC/OS-II as a target RTOS for the purpose of its performance improvement. The proposed architecture for uC/OS-II is implemented and analyzed with the performance comparison.

• Journal of the Korea Institute of Military Science and Technology
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• v.12 no.5
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• pp.601-608
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• 2009

Interoperability is the key issue in NCW. However, old-fashioned weapon systems have low level interoperability. The representative example is BTCS. Therefore, we apply KVMF R1 to BTCS in order to improve interoperability and testify the effectiveness of how to apply without any changes in existing software. In this paper, we have proposed a message and software architecture design method for applying KVMF to developed weapon system. Finally, it is confirmed that the proposed method is superior to apply KVMF to existing weapon system in a point of verifying how to highly efficiently apply KVMF on existing weapon system.

• Molecular & Cellular Toxicology
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• v.2 no.3
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• pp.212-215
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• 2006

Several reports have suggested a possible relationship between blood coagulation factors and schizophrenia. Plasminogen activator inhibitor type 1 (PAI-1) belongs to a serine protease inhibitor family, which regulates fibrinolysis and proteolysis by inhibiting plasminogen activation. The purpose of this study was to investigate the association of polymorphisms of the PAI-1 gene with schizophrenia in Korean population. Two important polymorphisms (-675 4G/5G and -844 G/A) located on promoter region of the PAI-1 gene were analyzed on 178 schizophrenia patients and 226 controls. The genotypic and allelic associations of -675 4G/5G were found significant. Furthermore, haplotype analysis revealed significant result, which suggests that -675 4G/5G polymorphism might confer increased susceptibility for schizophrenia in Korean population.

• The Korean Journal of Physiology and Pharmacology
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• v.14 no.4
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• pp.199-204
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• 2010

The potential therapeutic action of shikonin in an experimental model of rheumatoid arthritis (RA) was investigated. As a RA animal model, DBA/1J mice were immunized two times with type II collagen. After the second collagen immunization, mice were orally administered shikonin (2 mg/kg) once a day for 35 days, and the incidence, clinical score, bone mineral density (BMD), bone mineral content (BMC) and joint histopathology were evaluated. BMD in the proximal regions of the tibia largely increased in the shikonin treatment group compared with the control group. We also examined the effect of shikonin on inflammatory cytokines and cartilage protection. Shikonin treatment significantly reduced the incidence and severity of collagen-induced arthritis (CIA), markedly abrogating joint swelling and cartilage destruction. Shikonin also significantly inhibited the production of matrix metalloproteinase (MMP)-1 and up-regulated tissue inhibitors of metalloproteinase (TIMP)-1 in mice with CIA. In conclusion, shikonin exerted therapeutic effects through regulation of MMP/TIMP; these results suggest that shikonin is an outstanding candidate as a cartilage protective medicine for RA.

• Journal of Ginseng Research
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• v.41 no.4
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• pp.566-571
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• 2017

Background: A number of reports have described the protective effects of ginsenoside Rg1 (Rg1) in Alzheimer's disease (AD). However, the protective mechanisms of Rg1 in AD remain elusive. Methods: To investigate the potential mechanisms of Rg1 in ${\beta}$-amyloid peptide-treated SH-SY5Y cells, a comparative proteomic analysis was performed using stable isotope labeling with amino acids in cell culture combined with nano-LC-MS/MS. Results: We identified a total of 1,149 proteins in three independent experiments. Forty-nine proteins were significantly altered by Rg1 after exposure of the cells to ${\beta}$-amyloid peptides. The protein interaction network analysis showed that these altered proteins were clustered in ribosomal proteins, mitochondria, the actin cytoskeleton, and splicing proteins. Among these proteins, mitochondrial proteins containing HSD17B10, AARS2, TOMM40, VDAC1, COX5A, and NDUFA4 were associated with mitochondrial dysfunction in the pathogenesis of AD. Conclusion: Our results suggest that mitochondrial proteins may be related to the protective mechanisms of Rg1 in AD.

• Journal of Acupuncture Research
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• v.17 no.3
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• pp.168-175
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• 2000

Stimulation of the auricle is known to be effective in reducing obesity. The aim of the present study is to investigate whether stimulating a specific auricular acupuncture point is effective on suppression of appetite. Cholesystokinin (CCK) is known to induce a powerful feeding response after central administration and particularly abundant in the cerebral cortex. In food-deprived rats exhibiting a strong drive for feeding, decreased CCK release was markedly detected in the cerebral cortex of the brain. Needling the fasted rats on the specific auricular region increased the CCK level of the cerebral cortex. In conclusion, stimulating the specific auricular points increases CCK-expression in the cerebral cortex of the fasted rats and may be useful for controlling obesity.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2010.04a
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• pp.200-206
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• 2010

본 논문은 풍력발전 시스템의 하부 지지 구조물인 타워의 플랜지 연결부 설계 평가를 위한 플랜지 모델건전성 평가 기법에 대해 다룬다. 일반적으로 풍력발전 시스템 타워의 연결부는 Ring-형 플랜지의 형태를 가지고 있다. 이러한 ring-형 플랜지에 대한 설계 기준 및 방법은 풍력 발전 시스템 기술기준 등 에 명시되어있다. 이러한 설계 기준을 따르는 플랜지 연결부에 대해 구조 및 체결 볼트의 건전성 평가를 위해 하중평가 전용 프로그램인 GH-Bladed 3.8를 통해 생성된 하중 데이터를 유한요소 범용 프로그램인 Ansys 12.0에 접목하여 구조해석을 수행 하였다. 해석 방법은 풍력발전시스템의 타워를 셸 요소로 모델링하여 계산한 해석 결과를 플랜지 모델의 경계면에 적용 시켜 해석하는 submodeling 기법과 타워를 빔의 형태로 단순화 화여 계산한 거동 결과를 플랜지 모델에 적용하는 기법을 사용 하였다. 이 두 가지의 해석 기법으로 도출된 결과의 비교를 통하여 해석 결과 신뢰성을 평가하고 효율적이고 합리적인 방법을 제시하고자 하였다.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.5
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• pp.1111-1116
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• 2006

Medical science is an area of study that focuses on maintaining health and treating disease. However, modern medicine focuses on treating disease and neglects methodology of maintaining health. Although the definition of heal this defined by the World Health Organization (WHO) and as the concept of harmonizing Yin and Yang in Korean medicine, there is no specific details regarding the definition. Thus, the following conclusion was obtained after the concept of health is viewed through Yin-Yang(陰陽), Vital Essence(精), Qi(氣), and Healthy Person(平人). Although Yin and Yang have opposite properties, they work very closely, maintaining the overall balance and harmony. Secondly, Vin and Yang would each function by the effects of one another, and the body could maintain normal physiological activities through this function. Thirdly, it maintains normal physiological state through the ascending Kidney-Water and descending Heart-Yang(水升火降). Fourthly, Vital Essence is divided into the congenital Essence(先天之精) and the acquired Essence(後天之精) in which the former is related with reproduction and the latter, nourishing. Fifthly, Qi is resistant to pathogens and related with the physique so that Qi and physique should be balanced. Sixthly, Healthy Person is the state where the exchange of Qi-Blood is active.