• KIPS Transactions on Software and Data Engineering
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• v.12 no.1
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• pp.51-58
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• 2023

In this paper, we propose an organ segmentation technique for the automatic extraction of medical diagnostic indicators from X-ray images. In order to calculate diagnostic indicators of heart disease and spinal disease such as VHS(vertebral heart scale) and Cobb angle, it is necessary to accurately segment the thoracic spine, carina, and heart in a chest X-ray image. A deep neural network model in which the high-resolution representation of the image for each layer and the structure converted into a low-resolution feature map are connected in parallel was adopted. This structure enables the relative position information in the image to be effectively reflected in the segmentation process. It is shown that learning performance can be improved by combining the OCR module, in which pixel information and object information are mutually interacted in a multi-step process, and the channel attention module, which allows each channel of the network to be reflected as different weight values. In addition, a method of augmenting learning data is presented in order to provide robust performance against changes in the position, shape, and size of the subject in the X-ray image. The effectiveness of the proposed theory was evaluated through an experiment using 145 human chest X-ray images and 118 animal X-ray images.

• Journal of Microbiology
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• v.45 no.6
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• pp.572-577
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• 2007

To enhance therapeutic potential of murine monoclonal antibody, humanization by CDR grafting is usually used to reduce immunogenic mouse residues. Most humanized antibodies still have mouse residues critical for antigen binding, but the mouse residues may evoke immune responses in humans. Previously, we constructed a new humanized version (AKA) of mouse CC49 antibody specific for tumor-associated glycoprotein, TAG-72. In this study, to select a completely human antibody light chain against TAG-72, guided selection strategy using phage display was used. The heavy chain variable region (VH) of AKA was used to guide the selection of a human TAG-72-specific light chain variable region (VL) from a human VL repertoire constructed from human PBL. Most of the selected VLs were identified to be originated from the members of the human germline VK1 family, whereas the VL of AKA is more homologous to the VK4 family. Competition binding assay of the selected Fabs with mouse CC49 suggested that the epitopes of the Fabs overlap with that of CC49. In addition, they showed better antigen-binding affinity compared to parental AKA. The selected human VLs may be used to guide the selection of human VHs to get completely human anti-TAG72 antibody.

• Korean Journal of Applied Biomechanics
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• v.15 no.1
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• pp.1-18
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• 2005

The purpose of this study was to evaluate performance characteristics. in the success of team attack during volleyball competition. For this, real game was analyzed using S-VHS video camera for three dimensional cinematography. The contents of this research were receive to set time, set to spike time, setter moving distance, ball position during set and attacker's relative ball position during jump and spike, and open area at spike. Among the various kinematical factors considered in this study, the ball height relative spiker and open area were found to be related to offensive performance. This finding implies that although their direct impact were not significant the other factors could have indirect impact on offensive performance by increasing open area. Thus, receiver, setter, assistant attacker, and main attacker should practice for successful performance in each stage. Lastly, it is necessary to develop kinematic variables to evaluate performance characteristics of players. Further study may consider the best defense position against the attack of the opponent player.

• Publications of The Korean Astronomical Society
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• v.13 no.1 s.14
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• pp.39-54
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• 1998

We have developed solar observational system in the department of Astronomy & Space Sciences of KyungHee University, in order to monitor solar activities and construct solar database for space weather forecasting at maximum of 23rd solar cycle, as well as an solar education and exercise for undergraduate students. Our solar observational system consists of the full disk monitoring system and the regional observation system for H a fine structure. Full disk monitoring system is made of an energy rejection filter, 16cm refractor, video CCD camera and monitor. Monitored data are recorded to VHS video tape and analog output of video CCD can be captured as digital images by the computer with video graphic card. Another system for regional observation of the sun is made of energy rejection filter, 21cm Schmidt-Cassegrain reflector, H a filter with 1.6A pass band width and $375\times242$ CCD camera. We can observe H a fine structure in active regions of solar disk and solar limb, by using this system. We have carried out intense solar observations for a test of our system. It is found that Quality of our H a image is as good as that of solar images provided by Space Environmental Center. In this paper, we introduce the basic characteristics of the KyungHee Solar Observation System and result of our solar observations. We hope that our data should be used for space weather forecasting with domestic data of RRL(Radio Research Laboratory) and SOFT(SOlar Flare Telescope).

• Proceedings of the KSME Conference
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• 2003.04a
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• pp.1845-1850
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• 2003

The underground utility tunnels are important facility as a mainstay of country because of communication developments. The communication and electrical duct banks as well as various utility lines for urban life are installed in the underground utility tunnel systems. If a fire breaks out in this life-line tunnel, the function of the city will be discontinued and the huge damages are occurred. In order to improve the safety of life-line tunnel systems and the fire detection, the behaviors of the fire-induced smoke flow and temperature distribution are investigated. In this study we assumed that the fire is occurred at the contact or connection points of cable. Numerical calculations are carried out using different velocity of ventilation in utility tunnel. The fire source is modeled as a volumetric heat source. Three-dimensional flow and thermal characteristics in the underground tunnel are solved by means of FVM (Finite Volume Method) using SIMPLE algorithm and standard ${\kappa}-{\varepsilon}$ model for Reynolds stress terms. The numerical results of the fire-induced flow characteristics in an underground utility tunnel with different velocity of ventilation are graphically prepared and discussed.

• Journal of Korean Neurosurgical Society
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• v.60 no.3
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• pp.380-384
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• 2017

Glioblastoma multiforme (GBM) is located most frequently in the cerebral hemispheres. Glioblastoma presenting as an extraaxial mass of cerebellopontine angle (CPA) is very rare in adults. We report a rare case of GBM arising in the CPA. The patient was a 71-year-old female, who complained of progressive gait disturbance and poor memory. Initial magnetic resonance imaging (MRI) revealed a $1.4{\times}1.3cm$ mass in the left CPA, with broad base to the petrous bone, showing homogenous enhancement. Follow-up MRI showed a rapid increase in size of mass ($2.7{\times}2.2cm$) with a necrotic portion. A stereotactic biopsy was done under the guidance of navigation system, and the histopathologic diagnosis was GBM, World Heath Organization grade IV. Further surgical resection was not performed considering her general condition, and the patient underwent concurrent chemotherapy with radiation therapy. Although rare, the possibility of glioblastoma should be included in the differential diagnosis of atypical CPA tumor.

• Proceedings of the KSME Conference
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• 2003.11a
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• pp.816-821
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• 2003

The pumping characteristics of a disk-type drag pump (DTDP) from free molecular flow region to the slip flow region are calculated by the direct simulation Monte Carlo (DSMC) method. In this study, the pumping performance is studied numerically for several channel depths. The interaction between molecules is modeled by variable hard-sphere (VHS). The no time counter method is used as a collision sampling technique. The clearance between rotor and stator is considered an effect on performance. Spiral channels are cut on both upper and lower sides of rotating disks, and stationary disks are planar. A three-dimensional DSMC method for the analysis of steady rarefied flows in a single-stage DTDP has been developed. Velocity and density fields were obtained by the DSMC simulation in the rotor. The present experimental data in the outlet pressure range of $7.5{\times}10^{-3}{\sim}4$ Torr were compared with the DSMC results in the single-stage DTDP. Comparison between the experimental data and DSMC results showed good agreement.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.52 no.6
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• pp.644-649
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• 2019

Killed vaccines, developed by inactivation with formalin, have been investigated for many fish viruses. In this study, the inactivation of viral hemorrhagic septicemia virus (VHSV) by formalin was investigated based on the infectivity titer. When viral cell culture supernatants were used, the infectivity titer decreased 1,000-fold at 1 d after treatment with 0.1% (v/v) formalin, but was below the detection limit at 7 and 14 d. Moreover, neither the N nor G gene were detectable by RT-PCR immediately after formalin treatment. In western blot analysis, N protein was not detected by rabbit antiserum against VHSV KR-9225 from 2 d after formalin treatment. On the other hand, when we used a virus that was purified and concentrated ~100 times, the infectivity titer was maintained at 10^6.05 TCID₅₀/mL, even at 14 d after formalin treatment, and no change in the viral structural proteins was observed. This study provides important data on the production and use of formalin-inactivated vaccines.

• Proceedings of the KOSOMBE Conference
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• v.1995 no.05
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• pp.164-166
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• 1995

The objectives of study are to develop a peripheral device on the endoscopic surgery system. These systems are consist of the following units. They are a color monitor of high resolution, light source, computer system and endoscopic camera with a C-mount head, irrigator, color video printer, Super VHS recorder and a system rack. The color monitor is a NTSC monitor for monitoring the image projected of the surgical section. The lightsource is necessary to irradiate the interior of a body via an optic fiber, The light projector will adapt the brightness in accordance with changing distance from the object. A miniature camera using a color CCD chip and computer system is used to capture and control an image of the surgical section[1]. The video printer is a 300 DPI resolution using thermal sublimation methods, which is developed by Samsung Electronics Co., Ltd. The specification of the endoscopic data management system is consist of storage of a captured image and pathological database of patients [2-4].

• Proceedings of the Korea Information Processing Society Conference
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• 2006.11a
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• pp.171-174
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• 2006

본 논문에서는 IP-TV 보금을 위해서 고성능 저가의 IP-TV(Internet Protocol TV) 셋탑박스의 필요성을 감안하여 TV를 통한 인터넷 컨텐츠 이용에 최적화된 IP-TV 셋탑박스를 제조업체(Ninelanes)와 공동으로 개발하였다. 개발된 셋탑박스는 브로드밴드를 이용한 VOD서비스, 1Mbps급의 DVD급 화질을 지원하고 스트리밍 비디오와 저장된 콘텐츠를 직접 재생할 수 있다. 개발된 셋탑박스는 VHS(450kbps), DVD급(750kbps), DVD(1.2Mbps), MP3, AC3, MPEG-2/4, VP4/5/6, WMV9, DVIX 등의 다양한 디지털 미디어 재생 포맷을 지원 할 수 있도록 개발되어 가격경쟁력 향상 및 멀티미디어 지원환경 구축, 인코더방식의 코덱 전환이 가능하다. 또한 고집적, 저전력, 고성능, 저가형 개발 개념으로 개발된 이 셋탑박스는 각종 IP-TV기능을 펌웨어나 소프트웨어 수정으로 시스템 변경이 가능하여 IP-TV 셋탑박스 보급에 크게 기여할 것으로 기대된다.