• Journal of the Korean GEO-environmental Society
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• v.13 no.2
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• pp.59-65
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• 2012

Solidification/Stabilization(S/S) is one of the remediation technologies that have been applied for treating inorganic hazardous wastes. This study investigated the reduction of arsenic concentration of arsenic-contaminated soil using by S/S. The binder plays a role in controlling the mobility and solubility of the contaminants in S/S process, so it is important to determine the optimum binder content. Therefore, this study evaluated the effectiveness of S/S using four different binders(cement, zero valent iron, and monosulfate and ettringite(cement-based synthesized materials) at the binder content ranged between 5%(wt.) and 20%(wt.). The leachability of arsenic in 1 N HCl was different depending on the types of binders: cement(71.41%) > monosulfate(47.45%) > ettringite(46.36%) > ZVI(33.08%) at the binder content of 20%. Additionally, three kinds of a mixture binder were prepared using cement and additives(monosulfate, ettringite, calcium sulfoaluminate(CSA)) and tested for arsenic reduction. The highest arsenic removal capacity was found at the mass ratio of cement to the additive, 4:1 in all experiments using a mixture binder, regardless of the additives types. A mixture binder(cement and additives) resulted in higher arsenic removal relative to the arsenic removal when cement was used alone.

• Korean Journal of Environmental Biology
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• v.35 no.3
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• pp.380-388
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• 2017

Factors affecting spatial distribution of halophytes were analyzed in June 2012 at the Goraebul coastal dunes. In the Goraebul sand dune, distribution of halophytes was divided into three groups. The first group belonging to Elymus mollis, Carex kobomugi, Calystegia soldanella, Ixeris repens and Glehnia littoralis was distributed in the ridge of primary sand dune and dune slack. The second group belonging to Lathyrus japonicus and Zoysia macrostachya was distributed in the dune slack. The third group belonging to Pinus thunbergii, Vitex rotundifolia and Linaria japonicus was distributed in the pine forest of the secondary sand dune. E. mollis, C. kobomugi, C. soldanella, I. repens and G. littoralis was distributed in relatively unstable habitat of sand dunes due to the large amount of sand movement. V. rotundifolia was distributed in a relatively stable habitat. Factors that have the greatest influence on distribution of halophytes in the Goraebul sand dunes are distance from the seashore, topography, and the pine forest. The Goraebul sand dune is a relatively well-preserved area with minimal human intervention. Therefore, different distribution of physico-chemical factors by natural processes is essential to spatial distribution of halophytes than other sand dunes in Korea. Significant natural processes in the Goraebul sand dunes were advance and retreat of coastlines from waves, erosion and sedimentation of sand due to wind and waves, and dispersal of seawater.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.6 no.1
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• pp.28-37
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• 1996

Benzidine, an aromatic amine used primarily in the manufacture of azo dyes, is recognized as a urinary bladder carcinogen in humans. In rats, mice, and hamsters, chronic exposure to benzidine resulted in tumors of the liver. The present study was undertaken to suggest analyzing the metabolites of benzidine with the optimal condition, identify the metabolites of benzidine, and observe time variance of the metabolites in the isolated perfusated rat liver. N-acetylbenzidine was synthesized by acetylation of benzidine with acetic anhydride and separated by thin layer chromatography(TLC) and high performance liquid chromatography(HPLC). To analysis benzidine and the metabolites of benzidine, HPLC operating condition has been optimized by means of preliminary experiment. The mobile phase consisted of acetonitrile(37%) in phosphate buffer, flow rate maintained at 1.0 ml/min. Optimal detective conditions were electrochemicaldetector(ECD) at 0.75 V for benzidine and N-acetylbenzidine and ultravioletdetector(UVD) at 287 nm for N,N'-diacetylbenzidine. The separation system was composed of a guard column and a separation column(Polymer C18, $4.6{\times}250cm$) at a temparature of $40^{\circ}C$. The perfusion system was equilibrated for 30 minutes before addition of benzidine to the perfusate. Samples of the perfusate were collected at time intervals(0, 10, 20, 30, 60, 90, 120 min) during the 2 hour perfusion. Before analyzing samples by HPLC/ECD/UVD, samples had been treated with sep-pak. Samples of perfusate analyzed by HPLC/ECD/UVD and the metabolites of benzidine in the isolated perfused rat liver were N-acetylbenzidine and N,N'-diacetylbenzidine. Benzidine metabolized over 60% during the initial 30 minutes of perfusion, extensively by 1 hour, and was undetectable in the perfusate. N-acetylbenzidine increased by 30 minutes of perfusion, declined. N,N'-diacetylbenzidine increased the 0-90 minutes period, remained constant during the 90-120 minutes period.

• Journal of Applied Biological Chemistry
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• v.61 no.2
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• pp.125-130
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• 2018

The quality and microbiological characteristics of various Mul-kimchi prepared with addition of 0.02, 0.05, and 0.1% (w/v) chlorella water extract (CWE) were investigated during fermentation for 7 days at $10^{\circ}C$. The addition of CWE powder stimulated the growth of lactic acid bacteria and considerably improved the acid production. After 6 days fermentation, titratable acidity of CWE Mul-kimchi was 0.16-0.19% and was higher than that (0.14%) of Mul-kimchi made without CWE. The lactic acid bacterial counts were increased rapidly in CWE Mul-kimchi during fermentation for 4 days. The sensory quality of Mul-kimchi added with 0.05-0.1% CWE powder lightly enhanced in taste and overall acceptability among the tested Mul-kimchis preparations. When CWE Mul-kimchi preparations fermented for 6 days were incubated at $4^{\circ}C$ for 15 days, their titratable acidities were continuously increased up to 0.21-0.26% but number of viable lactic acid bacteria were well maintained above $10^7CFU/g$ through storage period.

• Korean Journal of Environmental Agriculture
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• v.17 no.3
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• pp.189-194
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• 1998

In order to evaluate the residual effects of bituminous coal fly ash, gypsum, oyster shell as soil amendments, Chinese cabbage was cultivated on acidic sandy loam soils with low boron content. The soils were amended in the upper 15cm with amendments in previous year and the growth and qualities of plants were analyzed. Amendments treated one year before were, in metric tons per hectare, i) none(Check) ; ii) 80 fly ash(FA) ; iii) 4 shell(SH) ; iv) 56 fly ash + 24 gypsum (FG) ; v) 40 fly ash + 24 gypsum + 0.8 shell(FGS). Yield response in fresh weight of Chinese cabbage was in order of 834% for FGS > 780% for FG > 755% FA > 193% for SH plants. Reducing sugar, vitamin-C, and total nitrogen contents of leaves depending on treatments showed the same tendencies as that in yields, whereas crude fibre opposite to them. In particular, FA, FG, and FGS plants showed normal growth without both boron deficiency symptoms which appeared in Check and SH plants and possibilities of accumulation of heavy metals. In any soils treated with the above amendments, however, magnesium was insufficient.

• The Journal of the Korean life insurance medical association
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• v.2 no.1
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• pp.34-36
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• 1985

Korea is an endemic area of chronic hepatitis in the world. Liver cirrhosis and liver cell carcinoma, presumed to be related to such chronic hepatitis, are the major causes of death in this country. The purpose of this study is disclosing the sources of chronic hepatitis in Korea establishing its histologic characteristics, disclosing the patterns of progression in chronic hepatitis, delineating its prognosis and finally speculating its etiology. The study group was composed of 183 patients with biopsy-proven acute icteric viral hepaticis, 32 patients with biopsy- proven anicteric hepatitis and 260 patients with biopsy- proven chronic hepatitis. These patients submitted to long-term follow-up by means of liver needle biopsy and/or clinicolaboratory evaluation. The period of follow-up ranged from two months to 18 years. The histological features of the initial biopsy specimens of chronic hepatitis permitted a division of the cases cases into the following five types: Type I. Persisting portal hepatitis : so called persisting hepatitis 43 Type II. Chronic inactive hepatitis with incomplete strand septal fibrosis. This type has thin fibrotic septation in addition to Type I with portal sclerosis 38 Type III. Chronic active periportal hepatitis(CAPH) : so called aggressive hepatitis, characterized by marked piecemeal necrosis. This type has been subdivided further into three groups: AB and C on the basis of histologic features. A CAPH without cirrhosis 15 B CAPH with cirrhosis 99 C CAPH with diffuse acinus type parenchymal nodules; characterized by rosette-forming micronodules 21 Type IV. Subacute hepatic necrosis; characterized by multilobular and/or bridging necrosis. 14 Type V. Persisting lobular hepatitis; characterized by spotty necrosis, which looks very similar to acute viral hepatitis. Such histologic changes should be persisted for more than six months 30 In Korea the main source of chronic hepatitis is the anicteric type. Of the chronic hepatitis observed in the hospital, Type IIIb was the most frequent in its incidence and occasionally exhibited development of hepatocellular carcinoma, but the mortality was highest in Type IIIc during the period of follow-up. Histologic characteristics of these five types suggest a spectrum of chronic hepatitis in Korea from an early and mild stage to advanced and fatal cirrhosis, which is occasionally associated with primary hepatic cell carcinoma. It seems that Type IV can be followed by flare-up of various stages of acute and chronic hepatitis with HBsAg and that many cases of liver cirrhosis prevalent in Korea occur through such an active process of Type IV. The etiology is not established, but in Korea it is mainly related to HBsAg.

• Journal of Korean Society for Atmospheric Environment
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• v.29 no.1
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• pp.97-104
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• 2013

Methyl alcohol is one of the basic intermediates in the chemical industry and is also being used as a fuel additive and as a clean burning fuel. In this study, conversion of carbon dioxide to methyl alcohol was investigated using catalytic chemical methods. Ceramic monoliths (M) with $400cell/in^2$ were used as catalyst supports. Monolith-supported CuO-ZnO catalysts were prepared by wash-coat method. The prepared catalysts were characterized by using ICP analysis, TEM images and XRD patterns. The catalytic activity for carbon dioxide hydrogenation to methyl alcohol was investigated using a flow-type reactor under various reaction temperature, pressure and contact time. In the preparation of monolith-supported CuO-ZnO catalysts by wash-coat method, proper concentration of precursors solution was 25.7% (w/v). The mixed crystal of CuO and ZnO was well supported on monolith. And it was known that more CuO component may be supported than ZnO component. Conversion of carbon dioxide was increased with increasing reaction temperature, but methyl alcohol selectivity was decreased. Optimum reaction temperature was about $250^{\circ}C$ under 20 atm because of the reverse water gas shift reaction. Maximum yield of methyl alcohol over CuO-ZnO/M catalyst was 5.1 mol% at $250^{\circ}C$ and 20 atm.

• Journal of the Society of Naval Architects of Korea
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• v.33 no.2
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• pp.30-35
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• 1996

It is well known that the improved methods of the estimation of the service power margin is necessary to design a optimum ship and to operate economically a ship. Unfortunately, most conventional methods of the predicting of the service power margin are not so accurate that attention should be payed to improve this. From this overview, it is importance with. the effects of waves, as recommended by the 15th and 16th International Towing Tank Conference in 1978 and l981. However the progress of research in this field is very slow mainly since it is taken so long time to take data about hull roughness according to ship ages. For instance, it would be taken 17 or 25 years to measure ideally the data for a ship. Moreover it would be also necessary to take data for many types of ships to lead a general solution. A relationship between roughness and ship age are studied in this paper considering full scale data. A comparison is also made between the effects of hull roughness and of weather at sea for the ship.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.18
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• pp.8503-8512
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• 2016

The purpose of this study was to provide a detailed explanation of the mechanism of bisanthracycline, WP 631 in comparison to doxorubicin (DOX), a first generation anthracycline, currently the most widely used pharmaceutical in clinical oncology. Experiments were performed in SKOV-3 ovarian cancer cells which are otherwise resistant to standard drugs such as cis-platinum and adriamycin. As attention was focused on the ability of WP 631 to induce apoptosis, this was examined using a double staining method with Annexin V and propidium iodide probes, with measurement of the level of intracellular calcium ions and cytosolic cytochrome c. The western blotting technique was performed to confirm PARP cleavage. We also investigated the involvement of caspase activation and DNA degradation (comet assay and immunocytochemical detection of phosphorylated H2AX histones) in the development of apoptotic events. WP 631 demonstrated significantly higher effectiveness as a pro-apoptotic drug than DOX. This was evident in the higher levels of markers of apoptosis, such as the externalization of phosphatidylserine and the elevated level of cytochrome c. An extension of incubation time led to an increase in intracellular calcium levels after treatment with DOX. Lower changes in the calcium content were associated with the influence of WP 631. DOX led to the activation of all tested caspases, 8, 9 and 3, whereas WP 631 only induced an increase in caspase 8 activity after 24h of treatment and consequently led to the cleavage of PARP. The lack of active caspase 3 had no outcome on the single and double-stranded DNA breaks. The obtained results show that WP 631 was considerably more genotoxic towards the investigated cell line than DOX. This effect was especially visible after longer times of incubation. The above detailed studies indicate that WP 631 generates early apoptosis and cell death independent of caspase-3, detected at relatively late time points. The observed differences in the mechanisms of the action of WP631 and DOX suggest that this bisanthracycline can be an effective alternative in ovarian cancer treatment.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.14 no.6
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• pp.1405-1415
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• 1994

The soil on the behavior of the nonlinear elastic work-hardening plasticity has a variety of stress paths due to the state of soil and the test conditions. The soil with a specific volume ${\upsilon}$ in principal stress space (${\sigma}_1$, ${\sigma}_2$, ${\sigma}_3$, and ${\upsilon}$v) displays the shape of an irregular hexagonal pyramid with an end cap. With variations of ${\upsilon}$ the size of the cap is changed but its shape remains unchanged and the movement of the cap is controlled by the increase or decrease of the plastic volumetric strain. By reflecting such a property of soil various cap models have been developed by researchers. In this thesis, a constitutive model of soil with a combination of the nonlinear elastic work-hardening plastic cap and the failure surfaces of Mohr-Coulomb (M-C cap model) has been developed. According to the the results of analyses using the work-hardening plastic cap model, the normally consolidated soil under shearing has experienced the work-hardening and plastic flow (movement of the cap). But in the shearing of the overconsolidated soil the elastic behavior is shown until the stress path has reached the failure surface and the cap does not move.