• Title/Summary/Keyword: V2C

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Design of Product-Line Architecture based-on Common Architecture (공통 아키텍처 기반 제품계열 아키텍처 설계)

  • Oh, Young-Bae;Shin, Sung-Oog;Kim, Young-Gab;Baik, Doo-Kwon
    • Journal of Information Technology Services
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    • v.5 no.2
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    • pp.155-168
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    • 2006
  • Software product line is a software product or a set of software system, which has common functions. We can develop a specific software product, which satisfies requirements of a particular market segment and a mission in a specific domain by reusing the core asset such as the developed software architecture through the software product line. Software development methodology based on the software product line can develop a software more easily and fast by reusing the developed software core asset. Developed countries of software technology select software product line as a core field of software production technology, and support technology development. In case of USA, CMU/SEI(Carnegie Mellon University/Software Engineering Institute) developed product-line framework 4.0 together with the industry and the Department of Defense. Europe is supporting the development of product line technology through ITEA(IT for European Advancement) program. However, industries in our country understand the necessity of software production technology based on product line concept for the purpose of increasing productivity, it is not sufficient to invest for this technology development. In this paper, we aim to construct the common architecture of software product line for production of the software product line.

VvpM Induces Human Cell Death via Multifarious Modes Including Necroptosis and Autophagy

  • Lee, Mi-Ae;Kim, Jeong-A;Shin, Mee-Young;Lee, Jeong K.;Park, Soon-Jung;Lee, Kyu-Ho
    • Journal of Microbiology and Biotechnology
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    • v.25 no.2
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    • pp.302-306
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    • 2015
  • VvpM, one of the extracellular metalloproteases produced by Vibrio vulnificus, induces apoptotic cell death via a pathway consisting of ERK activation, cytochrome c release, and activation of caspases-9 and -3. VvpM-treated cells also showed necrotic cell death as stained by propidium iodide (PI). The percentage of PI-stained cells was decreased by pretreatment with Necrostatin-1, indicating that VvpM-mediated cell death occurs through necroptosis. The appearance of autophagic vesicles and lipidated form of light-chain-3B in rVvpM-treated cells suggests an involvement of autophagy in this process. Therefore, the multifarious action of VvpM might be one of the factors responsible for V. vulnificus pathogenesis.

ELECTRICAL STIMULATION FOR THE RESTORATION OF GAIT FUNCTION IN HEMIPLEGIC PATIENTS (일측 마비환자의 전기자극에 의한 보행기능의 회복)

  • Jeong, D.H.;Park, B.R.;Kim, S.S.;Lee, C.H.;Hong, S.H.
    • Proceedings of the KOSOMBE Conference
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    • v.1992 no.05
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    • pp.203-208
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    • 1992
  • In order to restore the gait function by functional electrical stimulation(FES) in hemiplegic patients, an electrical stimulator and foot sensor were developed on the basis of optimal parameters which resulted from animal experiments. Physical properties of the soleus muscle were quite different from those of themedial gastrocnemius muscle, that is, the former had a characteristic or slow muscle and the letter had a characteristic of fast muscle in rats. Optimal parameters for electrical stimulation were 0.2ms of pulse width and 20Hz of frequency in the soleus muscle and 0.3ms, 40Hz in the medial gastrocnemius muscle. Amplitude modulated electrical stimulator with -15V of maximal output was made and automatic on-off time if the stimulator was 5 seconds. The foot sensor composed of 3 sensors in 3 pressure points of the foot was made in order to control the gai t function by closed loop feedback system. The gait function was improved by using the stimulator and foot sensor in peroneal palsy. These results suggest that the electrical stimulator with closed loop feedback system may restore the gait function in hemiplegic patients.

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A parallel-series type AC-DC converter with a fast dynamic response (빠른 동적 응답특성의 병렬-직렬 구조형 AD-DC 컨버터)

  • Chae, S.Y.;Hyun, B.C.;Kim, W.S.;Shin, J.W.;Cho, B.H.
    • Proceedings of the KIPE Conference
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    • 2008.06a
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    • pp.49-51
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    • 2008
  • 본 논문은 중용량급 전원회로의 구성을 간략화 할 수 있는 절연형 AC-DC 컨버터의 구조와 그 제어 방법을 제안한다. 제안하는 회로의 구조는 병렬 전력 처리를 기반으로 한다. 병렬 모듈의 기능을 각각 AC 입력 전류의 위상을 제어하는 역률개선(PFC) 기능과, 콘덴서에 저장된 에너지를 이용하여 DC 전압을 생성하는 DC-DC 컨버터의 기능으로 분리한다. 병렬 모듈의 최종 출력단을 서로 직렬 연결하여, PFC 모듈이 생성한 전압과 DC-DC 컨버터 모듈이 생성한 전압을 서로 더해서 출력하는 구조이다. 이러한 구조를 통해서 기존의 병렬형 AC-DC 컨버터에 대비하여 반도체 소자의 내압을 감소시킬 수 있고, 최종 DC 전압의 동작응답특성 향상이 가능하다. 회로의 동작모드 분석이 실시되었고, 제어기 구현 방법이 제시되었다. 제안된 구조는 PDP 전원회로에의 응용을 위해서 400W(출력전압-200V, 출력전류-2A)급 실험용 회로를 구현하여 동작검증을 실시하였다.

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Effect of L-Menthol on the Percutaneous Absorption of Ketorolac Tromethamine Across Human Cadaver Skin (사람 카다베르 피부를 통한 케토롤락 트로메타민의 경피 흡수에 L-menthol이 미치는 영향)

  • Lee, Yong-Seok;Oh, Heung-Seol;Kim, Ha-Hyung;Lee, Kwang-Pyo
    • YAKHAK HOEJI
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    • v.44 no.6
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    • pp.595-600
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    • 2000
  • Transdermal delivery of ketorolac tromethamine, a potent non-narcotic analgesic, through human cadaver skin was investigated in vitro. A mixture of ethanol/water (40/60) containing 0, 1, 3, 5, and 8 (w/v)% L-menthol were used as a vehicle and penetration enhancer respectively. The permeation of ketorolac through human cadaver skin from saturated drug solution was evaluated at $37^{\circ}C$ with modified Franz diffusion cell. The in vitro skin flux and lag time were $1.23\;{\pm}\;0.11\;{\mu}g/cm^2{\cdot}hr$ and $5.56\;{\pm}\;0.34\;hr$, respectively. The cumulative amount of penetrated ketorolac containing L-menthol in ethanol/water (40/60) binary system was increased by the following order; 3%, 5%, 8%, 1%, 0%, and the lag time was decresed by the following order; 3%, 5%, 8%, 0%, 1%. The results suggested that a potential use of 3% L-methol is an effective penetration enhancer of ketorolac tromethamine through the human cadaver skin.

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A Study on Flexural Behaviors of Sandwich Composites with Facesheets of Unequal Thickness (면재 두께가 다른 샌드위치 복합재의 굽힘 거동 연구)

  • Shin, Kwang-Bok;Lee, Jae-Youl;Ryu, Bong-Jo;Lee, Sang-Jin
    • Journal of the Korean Society for Railway
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    • v.10 no.2 s.39
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    • pp.201-210
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    • 2007
  • Sandwich composites made of glass fabric epoxy facesheets with aluminum honeycomb core or balsa core is considered for the structural design of bodyshell of a Korean Low Floor Bus. Initially, in order to select the optimal facesheet and core materials in design stage, the flexural response of a sandwich composite is a critical importance. In this study, theoretical formula which could easily and quickly evaluate and obtain the flexural responses such as deflection and flexural stiffness of a sandwich composite subjected to external load was established. This theory could calculate the flexural responses of sandwich composites with narrow as well as wide width and with facesheets of unequal thickness, and also distinguish between the bending and shear effects of deflection. Finite element analysis using ANSYS V10.0 was used to offer the best elements for real sandwich composites, and flexural test according to ASTM C393 was conducted to compare with the results of theoretical formula and finite element analysis. The results show that the flexural responses of sandwich composites using proposed theoretical formula is in good agreement with those of experiment and finite element method.

Measurement of Trap Parameters of $CaSO_4:Tm$ TLD using Glow Curve Fitting (Glow 곡선 Fitting에 의한 $CaSO_4:Tm$ TLD의 포획매개변수 측정)

  • Park, Myeong-Hwan;Kim, Sung-Hwan;Lee, Joon-Il;Kim, Do-Sung
    • Journal of radiological science and technology
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    • v.21 no.2
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    • pp.53-56
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    • 1998
  • Highly sensitive $CaSO_4:Tm$ TLD is fabricated and their trap parameters are determined. The glow curve of $CaSO_4:Tm$ consists of three glow peaks and these peaks are isolated by the thermal bleaching method. The isolated glow peaks are fitted by a least squares method. The activation energies are 0.68, 0.82 and 1.03 eV. The frequency factors are $8.09{\times}10^8,\;9.14{\times}10^8$ and $1.03{\times}10^9/s$, and the kinetic orders are 1.37, 1.54 and 1.68, respectively. The optimum temperature range of the main peak for radiation dosimetry is between 220 and $290^{\circ}C$.

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Observed Seasonal Variability of Barrier Layer in the Bay of Bengal

  • Thadathil, Pankajakshan;Muraleedharan, P.M.;Rao, R.R.;Somayajulu, Y.K.;Reddy, G.V.;Revichandran, C.
    • Proceedings of the KSRS Conference
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    • v.2
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    • pp.922-925
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    • 2006
  • The objective of this study is first to resolve the spatial and seasonal variability of BL in the bay using 'the most comprehensive' data set available for the bay and then to understand the formation mechanisms and variability in the light of the known dynamical and thermodynamical processes. The most recent study [Masson et al., 2002] on the BL variability in the bay was based on the World Ocean Atlas (WOA98) of Levitus [1998]. The temperature and salinity profiles in the bay have increased considerably after the release of WOA98. The WOA98, itself has been updated to WOA01 in 2001. Further, the deployment of ARGO profiling floats in the bay since 2002 has generated many additional profiles. In addition to the ARGO data and the updated WOA01, the hydrographic data collected from the bay under several Indian national programs and archived in the Indian Oceanographic Data Centre (IODC) was also considered in the present study. The WOA98 and WOA01 consist of only limited data from the IODC archive, especially from the Exclusive Economic Zone of India. Therefore, the combination of these data from the three different sources (WOA01, ARGO and IODC) provides ‘the most comprehensive data set’ for the bay to resolve the BLT structure and its variability in a much better scale than in the past.

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Oxygen Annealing Effect of SrTiO$_3$ Single Crystal Substrate Damaged by Ar$^+$ Ion Milling (Ar 이온 밀링으로 손상된 단결정 SrTiO$_3$ 기판의 산소 열처리 효과)

  • Choi, Hee-Seok;Hwang, Yun-Seok;Kim, Jin-Tae;Lee, Doon-Hoon;Lee, Soon-Gul;Park, Yong-Ki;Park, Jong-Chul
    • 한국초전도학회:학술대회논문집
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    • v.9
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    • pp.87-90
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    • 1999
  • We have studied the annealing effects of 570 (SrTiO$_3$) single crystal substrate and the I-V properties of step-edge junctions after Ar ion milling. YBa$_2Cu_3O_7$ (YBCO) thin films are fabricated on the substrates by using pulsed laser deposition (PLD) and photolithography. The surface of Ar ion milled substrate was characterized with atomic force microscope (AFM) and scanning electron microscope (SEM) images. After the substrate was damaged by milling, the critical current density of YBCO thin films deposited on the substrate was lowered. The annealing of the damaged substrate at about 1000 $^{\circ}C$ recovered the critical current density to that before the milling. Futhermore the annealing helped junction formation due to high quality film and increased the yield rate for the fabrication of high quality step-edge junction.

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An unrecorded species of Hemicycliophora litoralis (Criconematoidea: Hemicyliophorinae) from South Korea

  • Kang, Heonil;Eun, Geun;Ha, Jihye;Kim, Yongchul;Choi, Insoo;Kim, Donggeun
    • Journal of Species Research
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    • v.5 no.3
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    • pp.547-550
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    • 2016
  • Hemicycliophora litoralis is newly collected from Korea. Korean population is well matched and within a range of original description and additional record from Solomon island in de Man's of L, b, c, V, R, Rex, Ran, Roes, RV (ant), annule, excretory pore, stylet length, and tail length. Differences are observed in RV and RVan. RV and RVan of original description was 55 (48-69) and 14 (10-19) but Korean population is 68 (61-76) and 22 (19-24), respectively. H. litoralis described from Solomon island has RVan of 19.6 (17-23) and is similar to Korean population. H. litoralis from Solomon island has slight higher Rst value of 39 (35-59) compared to Korean population of 33.5 (29-38). The measurements of MB (%), s, G1, G2 values are newly given.