• 한국조사연구학회지:조사연구
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• 제8권1호
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• pp.1-30
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• 2007

본 연구에서는 6시그마에서 기대한 성과를 얻으려면 도입과정에서 일련의 단계를 거쳐야 한다는 가정을 하였으며 특히 조직성숙이 성과에 미치는 영향을 분석하고 있다. 6시그마에서 성과를 얻는 단계를 준비단계, 수용단계, 성숙단계로 정의하여 단계적 모형을 제시하였다. 준비단계는 다시 조직변화오인, 추진시스템요인으로 세분하였고, 결과변수인 성과는 시장경쟁력성과, 조직구성원성과, 재무성과로 구분하였다. 6시그마를 도입하여 기대한 성과를 얻으려면 이 단계를 순차적으로 거쳐야 한다는 가정을 토대로 단계모형과 경쟁모형을 설정하여 구조방정식 모형을 통하여 비교 분석하였다. 기업을 표본단위로 한 판단표집(judgement sampling)을 통해 설문자료를 수집 처리하였다. 최종적인 분석에는 281 업체에서 수집된 자료가 사용되었다. 6시그마를 도입하고자 하는 기업은 준비단계, 수용단계, 그리고 성숙단계까지 도달해야만 기대한 성과를 얻을 수 있다는 것을 분석결과로 제시한다. 즉, 준비와 수용만 되었다고 큰 성과를 얻는다기보다는 성숙단계까지 가야만 성과를 제대로 얻을 수 있음을 시사하고 있다.

• 한국조경학회지
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• 제28권2호
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• pp.10-16
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• 2000

The purpose of this study is to identify relationships between a central angle and a radius of curvature of divided roads in flat terrain of traditional villages, suggesting layout criteria for traditional villages: Nak-an, Sung-Eup, Ha-Whe. This study is sought to find the optimum model through the various SAS regression analyses. a regression analysis of this data was adopted to induce the relationship formula between a central angle of curve and a radius of curvature. Results of this study are as follows: 1) Most of the divided roads in traditional villages have a complex curve rather than a simple curve. 2) A central angle of curve has ranged from 11$^{\circ}$to 127$^{\circ}$, with a mean degree of 63.9. 3) In the lower level of central angle(11-40$^{\circ}$), the branch roads have distributed with a high frequency, but with a low frequency in the higher level of central angle(90-140$^{\circ}$). 4) A radius of curvature in the divided roads has ranged from 0.9m to 59.6, but half of the roads have concentrated on 1-6m of the curvature. 5) Compared to the result of hilly villages in previous study(Ahn, 1999), value of central angels in flat villages is lower than that of hilly villages, while a mean value of the curvature is higher than that of hilly villages. 6) A Non-linear regression analysis, resulting from the SAS application, was useful method to induce a relationship formula between a central angle and a radius of curvature in the branch roads. Our study's formula is as follow: R=100.3*EXP(-0.06*$\delta$)+3.91. 7) Our study model has less error than that of the Kishizuka's method, being applicable to a broader range of the branch roads. 8) A minimum radius of curvature in our study has showed 3.9m, suggesting to reconsider applications of the Kishizuka's(5.8m) in the footpass design, In the study for this presupposition model the efficiency and utility of it can be estimated to grow large according to how much and how far it includes both extremes of data. This study is for the application to a design in future through the numerical formula of divided roads of various traditional villages. The studies from now on will be about the quasi-hilly quasi-hilly village and hilly village supplementing these factors more.

• 유통과학연구
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• 제5권1호
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• pp.57-73
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• 2007

농산품의 물류관리 정보시스템의 최적화로 물류 정보수준에 따른 성과를 실증 분석하여 물류관리의 효율성과 효과성을 높이는 측면에서 개선방안을 제시하여 물류효율성을 향상시키는데 본 연구의 목적이 있다. 본 연구의 분석방향은 첫째, 조직특성 및 조직전략에 따라 정보기술수준은 물류성과에 영향을 미칠 것인지를 분석하였다. 물류성과는 고객물류서비스 향상과 판매물류비용절감으로 나누어서 측정을 하였다. 둘째, 물류정보시스템 활용수준과 정보기술은 직접적으로 물류성과에 어떠한 영향을 미치고 있는가를 분석하였다. 연구 결과에 의하면, 농산품 물류정보시스템 도입을 물류기업의 경쟁력 강화요인으로 인식하는 기업들은 비교적 물류정보기술 활용수준이 높았고 물류 정보시스템이 농산품 물류서비스 향상과 물류비 관리의 통합망을 구축하는 링크관리를 실시함으로서 농산품 물류 효율성을 높이고 있었다. 그러므로 농산품 물류기업의 물류경쟁력을 높이기 위하여 물류정보기술수준을 높여야 하고 농산품업체의 물류관리와 관련된 의사결정자의 정보마인드가 필요하고 물류업무의 표준화, 정보시스템의 구축전문 인력의 양성과 함께 물류교육이 뒷받침되어야 할 것이다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권12호
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• pp.7635-7638
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• 2013

Background: Sperm-associated antigen 9 (SPAG9) has been recently proposed as a novel biomarker for early diagnosis of several human tumors, including ovarian, cervical and breast cancers. Its clinical value remains to be clarified for endometrial cancer (EC). In this study, we investigated the utility of serum SPAG9 levels in diagnosis of EC and its association with important clinicopathological parameters. Materials and Methods: This cross-sectional study was performed at a tertiary women's referral center in Ankara, Turkey. Preoperative serum samples were collected from patients surgically treated for endometrial cancer between June 2012-April 2013. Similar aged women with a biopsy proven benign endometrium were used as controls. Serum SPAG9 levels were measured with an enzyme-linked immunosorbent assay (ELISA) method and assessed for links with clinicopathological factors. Receiver operating characteristic (ROC) curve analysis was performed to assess power of SPAG9 levels for EC prediction. P values less than 0.05 were considered statistically significant. Results: A total of 63 women with EC and 27 with benign endometrium were included in the study. Mean age in the EC group was $58.7{\pm}1.1$. Median SPAG9 levels in the EC and control groups were 18.3 (range, 12.7-53.8) and 14.1 (range, 4.3-65.3), respectively (p<0.001). A cut-off value of 17 ng/ml for SPAG9 predicted presence of malignant endometrium with 74% sensitivity and 83% specificity [Area under curve (AUC)=0.82, p<0.001]. SPAG9 levels did not demonstrate any significant association with histological type, FIGO stage, tumor grade, size, myometrial invasion, lymphovascular space invasion, cervical involvement, adnexal involvement, peritoneal cytology or lymph node status (all p>0.05). Conclusions: Testing for SPAG9 may be useful for early detection of EC in asymptomatic high-risk women. Its role in post-treatment follow-up and early detection of recurrence should be assessed in future trials.

• 한국콘텐츠학회논문지
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• 제20권7호
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• pp.404-416
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• 2020

홍수는 도시가 피할 수 없는 자연재해이다. 홍수 재해는 도시의 경제와 안전, 그리고 지속발전을 심각하게 저해한다. 수변 공간에 대한 개발과 건설 과정에서 기본적인 방재시설의 건축을 통해 홍수의 경제적 피해를 줄이고자 막대한 자본을 투입하더라도 이를 완전히 피할 수는 없으며. 재해 발생 후 도시의 재건 비용은 방재(防災)시설의 건설비용보다 훨씬 많은 비용을 필요로 한다. 최근 몇 년간 도시재건 등에 있어 탄성(resilient)이론은 학계의 광범위한 토론과 주목을 불러일으키며 도시의 문제해결에 관한 주제가 되어왔다. 즉, 탄성의 방재개념을 이론과 경험적 요소를 토대로 어떻게 실천으로 전환시켜야 하는지가 도시방재가 마주하고 있는 현실적 문제이다. 본 논문은 도시의 수변(공간) 완충지역(홍수 취약지역)여 관한 이론 문헌과 도시의 실천 사례연구를 통해 탄성 방재이론인 5R 요소를 명확화하고, 이에 따른 상세 대책을 제시하고자 한다. 또한, 도시의 수변완충지역을 중심으로 탄성 방재이론 요소의 도시수변(공간)계획에서의 실행 가능성을 강조하는 동시에 다음과 같은 두 가지 문제를 해결하고자 한다. 첫째, 방재계획수단을 이용해 도시수변토지의 개별 효용과 수변완충지역의 방재기능 간의 갈등을 완화하는 것과 둘째, 수변완충지역이 탄성 방재계획을 통해 방재 측면에서 홍수가 수반하는 문제에 최대한 대응할 수 있게 하는 것이다.

• 유통과학연구
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• 제12권10호
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• pp.123-128
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• 2014

Purpose - The purpose of the study is to reexamine the price fairness as practiced by low cost airlines, as a consumer has to experience such inconveniences as inferior airport transportation, extra fees on in-flight meals, and non-negotiable seats, and consumers evaluate such experiences keeping in mind their total costs. This evaluation includes price fairness and allows a reasonable and overall consideration of factors of low cost airlines. It tries to set up a measurement of the indicators consumers' perceptions of price fairness academically as it adapts price fairness to airline services which are renowned for price volatility. Research design, data, and methodology - The research proposes an alternative pricing strategy for the long term profit of low cost airlines after going over conflicts between the traditional theory of consumers' price perception mechanism and flexible fair policy of low cost airlines. It was meaningful when it relates to the early stage of the business, while it enhances the risks relating to the long term survival of low cost airlines. In addition, it is significant as it highlights the negative influences on consumers' perceptions of price fairness, as low cost airlines run on extremely low cost perspectives. Results - The results of the research provide insight into four perspectives, as consumers' perceptions of price fairness are influenced by the frequency and range of price changes and services. The first perspective is that it would lead to positive price evaluation when a low cost airline cuts prices frequently with little changes than one big change. It also would lead to the same result when it comes to necessary services. The second perspective is that one big increase of price would rather undermine the negative aspects of price changes than those of several smaller ones. The third perspective is that additional services would be good to consumers' perceptions of price fairness as compared to discount benefits with respect to the cost. Finally, a low cost airline should consider that consumers will change airlines or defer their flight schedule if the flight fares increase beyond their limits. Conclusions - Low cost airlines should reconsider their pricing policies for services that were provided free earlier. A consumer would not like discount benefits when made to pay for services that were, for long, free of charge. If a low cost airline can provide services with no charge, it should improve volumes if the costs are standardized and, moreover, should consider the charging fees. Alternatively, a consumer can choose between services and fair discount. Low cost airlines are implementing sales promotion strategies, as the competition is more intense than it used to be. In these days, they should regard services over sales promotion, as consumers may prefer to spend money on good premium services. Some differentiation in services could create a good market position for the airlines and, hence, good financial performance.

• 조명전기설비학회논문지
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• 제22권2호
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• pp.134-141
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• 2008

본 논문은 전력회사와 수용가가 실시간으로 상호 협력하면서 효율적으로 여름철 냉방부하를 관리하여 첨두부하를 저감하기 위한 기법에 대하여 기술한다. 전력회사가 필요 관리량을 수용가 측에 요청하면 부하관리 요청을 받은 수용가, 예를 들면 대규모 아파트 단지의 중앙 지능관리 서버(Central Intelligent Management Server: CIMS)가 자율적인 관리를 통하여 요구받은 관리전력 이내로 부하율을 조정하도록 한다. 부하율을 관리하기 위한 수단으로CIMS는 필요 관리 부하전력에 따라 냉방기를 가동할 수 있는 권리에 해당하는 적정 수의 토큰(Token)을 발행하고 각 세대내의 냉방기를 제어할 수 있는 다수의 로컬 지능관리 서버(Local Intelligent Management Server: LIMS)들이 각 집안의 상황에 따라 냉방기를 가동하기 원할 경우에 전체 관리 서버에게 냉방기를 가동할 수 있는 권리에 해당하는 토큰을 요청하도록 한다. CIMS는 LIMS들의 토큰 요청을 관리하기 위한 큐(Queue)를 구성하여 관리하고 토큰을 요구한 각 LIMS들은 토큰을 할당받는 대로 자신이 담당하는 세대내의 냉방기를 가동하고 일정조건이 만족되면 자율 또는 타율로 토큰을 반납하여 큐에서 기다리는 다른 LIMS들에게도 토큰이 할당될 수 있도록 한다. 큐 운영 정책에 다양한 냉방기 운용 환경 정보를 반영하고 CIMS와 LIMS간에 원만한 상호 협력을 위하여 지능형 멀티 에이전트(Multi-Agent) 시스템으로 구성하고 이들을 계층구조의 네트워크로 연결하였다. 제안하는 기법을 서울의 한 아파트단지의 여름철 전력수요 데이터를 예로 하여 예상되는 대기 시간과 지원 받을 수 있는 전력요금 규모를 산정해 보았으며, 비교적 적은 수용가의 불편으로 큰 부하관리 효과를 얻을 수 있는 것을 알 수 있었다.

• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 2002년도 Proceedings of the International Welding/Joining Conference-Korea
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• pp.235-243
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• 2002

Ni-base superalloys are used extensively in industry, both in aeroengines and land based turbines. About 60% by weight of most modern gas turbine engine structural components are made of Ni-base superalloys. To satisfy practical demands, the efficiency of gas turbine engines has been steadily and systematically increased by design modifications to handle higher turbine inlet or firing temperatures. However, the increase in operating temperatures has lead to a decrease in the life of components and increase in costs of replacement. Moreover, around 80% of the large frame size industrial/utility gas turbines operating in the world today were installed in the mid-sixties to early seventies and are now 25 to 30 years old. Consequently, there are greater opportunities now to repair and refurbish the older models. Basically, there are two major factors influencing the weldability of the cast alloys: strain-age cracking and liquation cracking. Susceptibility to strain-age cracking is due to the total Ti plus AI content of the alloy; Liquation cracking is due either to the presence of low melting constituents or constitutional liquation of constituents. Though Rene 41 superalloy has 4.5wt.% total Ti and Al content and falls just below the safe limit proposed by Prager et al., controlled grain size and special heat treatments are needed to obtain crack-free welds. Varying heat treatments and filler materials were used in a laboratory study, then the actual welding of service parts was carried out to verity the possibility of crack-tree weld of components fabricated from Rene 41 superalloy. The microstructural observations indicated that there were two kinds of carbides in the FCC matrix. MC carbides were located along the grain boundaries, while M$_{23}$C$_{6}$ carbide was located both inter and intra granularly. Two kinds of filler materials, Rene 41 and Hastelloy X were used to gas tungsten arc weld a patch into the sheet metal, along with varying pre-weld heat treatments. The microstructure, hardness and tensile tests were determined. The service distressed parts were categorized into three classes: with large cracks, with medium cracks and with small or no visible cracks. No significant difference in microstructure among the specimens was observed. Specimens were cut from the corner and the straight edge of the patch repair, away from the corner. The only cracks present were found to be associated with inadequate surface preparation to remove oxidation. Guidelines for oxide removal and the welding procedures developed in the research enabled crack-free welds to be produced.d.

• Asian Pacific Journal of Cancer Prevention
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• 제16권18호
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• pp.8579-8587
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• 2016

Background: The molecular mechanisms linking breast cancer progression and inflammation still remain obscure. The aim of the present study was to investigate the possible association of angiopoeitin like protein 4 (ANGPTL4) and its regulatory factor, hypoxia inducible factor-$1{\alpha}$ (HIF-$1{\alpha}$), with the inflammatory markers nuclear factor kappa B/p65 (NF-${\kappa}B$/P65) and interleukin-1 beta (IL-$1{\beta}$) in order to evaluate their role in inflammation associated breast cancer progression. Materials and Methods: Angiopoietin-like protein 4 (ANGPTL4) mRNA expressions were evaluated using quantitative real time PCR and its protein expression by immunohistochemistry. DNA binding activity of NF-${\kappa}B$/P65 was evaluated by transcription factor binding immunoassay. Serum levels of ANGPTL4, HIF-$1{\alpha}$ and IL-$1{\beta}$ were immunoassayed. Tumor clinico-pathological features were investigated. Results: ANGPTL4 mRNA expressions and serum levels were significantly higher in high grade breast carcinoma ($1.47{\pm}0.31$ and $184.98{\pm}18.18$, respectively) compared to low grade carcinoma ($1.21{\pm}0.32$ and $171.76{\pm}7.58$, respectively) and controls ($0.70{\pm}0.02$ and $65.34{\pm}6.41$, respectively), (p<0.05). Also, ANGPTL4 high/moderate protein expression was positively correlated with tumor clinico-pathological features. In addition, serum levels of HIF-$1{\alpha}$ and IL-$1{\beta}$ as well as NF-${\kappa}B$/P65 DNA binding activity were significantly higher in high grade breast carcinoma ($148.54{\pm}14.20$, $0.79{\pm}0.03$ and $247.13{\pm}44.35$ respectively) than their values in low grade carcinoma ( $139.14{\pm}5.83$, $0.34{\pm}0.02$ and $184.23{\pm}37.75$, respectively) and controls ($33.95{\pm}3.11$, $0.11{\pm}0.02$ and $7.83{\pm}0.92$, respectively), (p<0.001). Conclusion: ANGPTL4 high serum levels and tissue expressions in advanced grade breast cancer, in addition to its positive correlation with tumor clinico-pathological features and HIF-$1{\alpha}$ could highlight its role as one of the signaling factors involved in breast cancer progression. Moreover, novel correlations were found between ANGPTL4 and the inflammatory markers, IL-$1{\beta}$ and NF-${\kappa}B$/p65, in breast cancer, which may emphasize the utility of these markers as potential tools for understanding interactions for axes of carcinogenesis and inflammation contributed for cancer progression. It is thus hoped that the findings reported here would assist in the development of new breast cancer management strategies that would promote patients' quality of life and ultimately improve clinical outcomes. However, large-scale studies are needed to verify these results.

• Nuclear Engineering and Technology
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• 제52권6호
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• pp.1120-1130
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• 2020

The CREOLE experiment performed In the EOLE critical facility located In the Nuclear Center of CADARACHE - CEA have allowed us to get interesting and complete experimental information on the temperature effects in the light water reactor lattices. To analyze these experiments with accuracy an elaborate calculation scheme using the Monte Carlo method implemented in the MCNP6.1 code and the ENDF/B-VII.1 cross section library has been developed. We have used the ENDF/B-VII.1 data provided with the MCNP6.1.1 version in ACE format and the Makxsf utility to handle the data in the specific temperatures not available in the MCNP6.1.1 original library. The main purpose of this analysis is the qualification of the ENDF/B-VII.1 nuclear data for the prediction of the Reactivity Temperature Coefficient while ensuring the ability of the MCNP6.1 system to model such a complex experiment as CREOLE. We have analyzed the case of UO₂ lattice with 1166 ppm of boron in ordinary water moderator in specified temperatures. A detailed comparison of the calculated effective multiplication factors with the reference ones [1] in room temperature presented in this work shows a good agreement demonstrating the validation of our 3D calculation model. The discrepancies between calculations and the differential measurements of the Reactivity Temperature Coefficient for the analyzed configuration are relatively small: the maximum discrepancy doesn't exceed 1,1 pcm/℃. In addition to the analysis of direct differential measurements of the reactivity temperature coefficient performed in the poisoned UO₂ lattice configuration, we have also analyzed integral measurements in UO₂ clean lattice configuration using equivalency of the integral temperature reactivity worth with the driver core fuel reactivity worth and soluble boron reactivity worth. In this case both of the ENDF/B-VII.1 and JENDL.4 libraries were used in our analysis and the obtained results are very similar.