• Korean Journal of Radiology
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• 제20권1호
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• pp.18-33
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• 2019

In this study, we summarize the clinical role of magnetic resonance imaging (MRI) in the diagnosis of patients with malignant uterine neoplasms, including leiomyosarcoma, endometrial stromal sarcoma, adenosarcoma, uterine carcinosarcoma, and endometrial cancer, with emphasis on the challenges and disadvantages. MRI plays an essential role in patients with uterine malignancy, for the purpose of tumor detection, primary staging, and treatment planning. MRI has advanced in scope beyond the visualization of the many aspects of anatomical structures, including diffusion-weighted imaging, dynamic contrast enhancement-MRI, and magnetic resonance spectroscopy. Emerging technologies coupled with the use of artificial intelligence in MRI are expected to lead to progressive improvement in case management of malignant uterine neoplasms.

• Korean Journal of Radiology
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• 제1권1호
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• pp.51-55
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• 2000

Objective: To determine the accuracy of CT and positron emission tomography (PET) in the diagnosis of recurrent uterine cervical cancer. Materials and Methods: Imaging findings of CT and PET in 36 patients (mean age, 53 years) in whom recurrent uterine cervical cancer was suspected were analyzed retrospectively. Between October 1997 and May 1998, they had undergone surgery and/or radiation therapy. Tumor recurrence was confirmed by pathologic examination or follow-up studies. Results: In detecting recurrent uterine cervical cancer, the sensitivity, specificity, and accuracy of CT were 77.8%, 83.3%, and 80.5%, respectively, while for PET, the corresponding figures were 100%, 94.4%, and 97.2%. The Chi-square test revealed no significant difference in specificity (p = .2888), but significant differences in sensitivity (p = .0339) and accuracy (p = .0244). Conclusion: PET proved to be a reliable screening method for detecting recurrent uterine cervical cancer, but to determine the anatomical localization of recurrent tumors, and thus decide an adequate treatment plan, CT was eventually needed.

• 대한수의학회지
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• 제62권2호
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• pp.11.1-11.4
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• 2022

A captive female capybara (Hydrochoerus hydrochaeris) of unknown age discharged a bloody mass from the vaginal region. A histopathology examination revealed the mass to be a reproductive leiomyosarcoma, and an ovariohysterectomy was performed. The histopathology examination confirmed that the excised tissue was a uterine leiomyosarcoma. The purpose of this report is to describe clinical history and histopathological diagnosis of leiomyosarcoma in capybaras. This report is novel because it describes the first diagnosis of uterine leiomyosarcoma in a capybara. Since clinical data about capybaras are rare, this case report will help to diagnosis and treat reproductive diseases of this species.

• Korean Journal of Radiology
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• 제1권4호
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• pp.198-207
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• 2000

Uterine cervical carcinoma is one of the most common malignant tumors occurring in females. After primary treatment, patients are usually followed up with CT or MRI and the findings of these modalities may be the first sign of recurrent disease. Because earlier additional treatment by chemotherapy or radiation therapy may improve the prognosis, the early detection of recurrent cervical carcinoma is clinically important. In this article, we review the CT and MR imaging findings of recurrent uterine cervical carcinoma, and assign them to one of four groups: a) recurrence at the primary site, involving the intrapelvic organs, b) extension to the pelvic side-wall, c) metastases to pelvic and extrapelvic lymph nodes, or d) metastases to distant organs. A further contribution of CT and MR imaging is the detection of hydronephrosis due to ureteral obstruction. The cases in each group are illustrated and discussed, and since an awareness of the spectrum of imaging findings of recurrent cervical carcinoma is likely to lead to its early detection, radiologists should be familiar with the information presented.

• 기본간호학회지
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• 제14권4호
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• pp.457-465
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• 2007

Purpose: This study was done to analyze symptom distress and spiritual well-being in patients with cancer according cancer diagnosis, metastasis, treatment stage, number of hospitalizations and treatment modality. Method: The participants, 285 patients being treated in one of ten general hospitals either as in- or out-patients, completed the McCorkle and Young(1978) Symptom Distress Scale translated and adapted by Uhm(1986) and the Spiritual Well-Being Scale by Paloutzian and Ellison(1982) translated by Choi(1990). Data collection was done from June 19 to September 30, 2006. Results: For symptom distress, there were significant differences for cancer diagnosis(p=.018), metastasis(p=.000), treatment stage(p=.000), number of hospitalizations(p=.000), and treatment modality(p=.002). For spiritual well-being, the only significant difference was for cancer diagnosis(p=.002). Patients with ovarian/uterine cancer had the lowest spiritual well-being. Conclusion: For patients with cancer, symptom distress was significantly different for illness and treatment factors, in particular, stage of illness, while for spiritual well-being, patients with uterine ovarian cancer had the lowest spiritual level. These results indicate a need to develop nursing interventions to decrease symptom distress in patients according to treatment stage and to promote spiritual well-being, particularly in women with ovarian/uterine cancer.

• 한국산학기술학회논문지
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• 제19권4호
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• pp.403-411
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• 2018

본 연구의 목적은 현상학적 접근을 통하여 고강도 초음파 치료를 받은 자궁양성종양 환자에 대한 경험의 본질을 심도 있게 파악하기 위해 이루어졌다. 연구 대상자는 자궁양성종양을 진단받고 고강도 초음파 집속술 치료를 받은 5명의 환자였다. 본 연구의 자료 수집은 2018년 2월부터 3월까지 이루어졌으며, 고강도 초음파 집속술을 시술하고 있는 D시 여성전문병원에서 시행되었다. 연구방법은 일대일 심층 면담을 통해 이루어졌으며, 자료는 비구조적이고 개방된 질문형태를 사용하여 자신의 의견과 경험을 자유롭고 유연하게 표현할 수 있도록 하였다. 인터뷰 자료는 Colaizzi의 현상학적 분석 방법을 사용하였다. 연구결과 5명의 대상자로부터 얻은 고강도 초음파 집속술 치료에 따른 건강문제는 총 3개의 범주로 구성되었고, 각각의 범주는 다시 하부 요인으로 구성되었다. 3개의 범주로는 '불편감', '양가감정', '의지와 요구' 로 나타났다. 본 연구는 고강도 초음파 치료를 받은 자궁양성종양 환자들의 경험을 이해하는데 도움을 줄 것이다. 나아가 본 결과는 향후 여성건강을 위한 새로운 치료법의 개발과 발전에 따라 올바른 간호학적 이해 및 고강도 초음파 치료를 받는 환자에 대한 지속적인 연구와 효과적인 간호 교육프로그램 개발이 이어져야 할 것이다.

• 대한영상의학회지
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• 제84권1호
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• pp.127-149
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• 2023

자궁에 생기는 병변들의 특성을 파악하고 다른 골반강 내에 생기는 병변들과 감별하는 것은 추후 환자의 치료 방향을 결정하는데 있어 중요하다. 자궁의 병변에 대한 평가는 일차적으로 초음파로 이루어지며 자기공명영상이 추가적인 정보를 제공할 수 있다. 병변이 주로 어디에 위치하고 있는지, 병변의 경계와 범위, 내부의 성상 및 혈류공급 정도 등의 패턴 인식법에 기반해 자궁 병변을 평하가는 것은 양성과 악성병변을 구분하고 정확하고 효율적인 감별진단을 내리는 데 도움을 줄 수 있다.

• Journal of Chest Surgery
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• 제40권11호
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• pp.789-792
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• 2007

양성 전이성 평활근종은 조직학적으로는 양성이나 임상적으로 폐나 다른 장기로 원격전이를 하는 매우 드문 질환이다. 저자들은 10년 전 자궁평활근종 절제술을 시행한 환자의 폐에서 발견된 다발성 결절 일부를 흉강경 수술하에 절제하여 조직학적 및 면역염색검사로 양성 전이성 평활근종임을 진단할 수 있었다. 환자는 수술 후 종양의 크기 변화 및 특이 증상이 없으며 특별한 치료 없이 외래 추적관찰 중이다.

• 대한세포병리학회지
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• 제19권2호
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• pp.111-118
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• 2008

Background : Cervicovaginal cytology is a screening test of uterine cervical cancer. The sensitivity of cervicovaginal cytology is less than 50%, but studies of cytologic/histologic correlation are limited. We analyzed the diagnostic accuracy of cervicovaginal cytology in the detection of the squamous epithelial lesions of the uterine cervix and investigate the cause of diagnostic discordance. Materials and Methods : We collected a total of 481 sets of cervicovaginal cytology and biopsies over 5 years. The cytologic diagnoses were categorized based on The Bethesda System and the histologic diagnoses were classified as negative, flat condyloma, cervical intraepithelial neoplasia (CIN) I, CIN II, CIN III, or squamous cell carcinoma. Cytohistologic discrepancies were reviewed. Results: The concordance rate between the cytological and the histological diagnosis was 79.0%. The sensitivity and specificity of cervicovaginal cytology were 80.6% and 92.6%, respectively. Its positive predictive value and negative predictive value were 93.7% and 77.7%, respectively. The false negative rate was 19.4%. Among 54 false negative cytology cases, they were confirmed by histology as 50 flat condylomas, 2 CIN I, 1 CIN III, and 1 squamous cell carcinoma. The causes of false negative cytology were sampling errors in 75.6% and interpretation errors in 24.4%. The false positive rate was 7.4%. Among 15 false positive cytology cases, they were confirmed by histology as 12 atypical squamous cells of undetermined significance (ASCUS) and 3 low grade squamous intraepithelial lesions (LSIL). The cause of error was interpretation error in all cases. The overall diagnostic accuracy of cervicovaginal cytology was 85.7%. Conclusions : Cervicovaginal cytology shows high overall diagnostic accuracy and is a useful primary screen of uterine cervical cancer.

• The Korean Journal of Pain
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• 제34권4호
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• pp.375-393
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• 2021

Percutaneous osteoplasty (POP) is defined as the injection of bone cement into various painful bony lesions, refractory to conventional therapy, as an extended technique of percutaneous vertebroplasty (PVP). POP can be applied to benign osteochondral lesions and malignant metastatic lesions throughout the whole skeleton, whereas PVP is restricted to the vertebral body. Common spinal metastases occur in the thoracic (70%), lumbosacral (20%), and cervical (10%) vertebrae, in order of frequency. Extraspinal metastases into the ribs, scapulae, sternum, and humeral head commonly originate from lung and breast cancers; extraspinal metastases into the pelvis and femoral head come from prostate, urinary bladder, colon, and uterine cervical cancers. Pain is aggravated in the dependent (or weight bearing) position, or during movement (or respiration). The tenderness and imaging diagnosis should match. The supposed mechanism of pain relief in POP is the augmentation of damaged bones, thermal and chemical ablation of the nociceptive nerves, and local inhibition of tumor invasion. Adjacent (facet) joint injections may be needed prior to POP (PVP). The length and thickness of the applied needle should be chosen according to the targeted bone. Bone cement is also selected by its osteoconduction, osteoinduction, and osteogenesis. Needle route should be chosen as a shortcut to reach the target bony lesions, without damage to the nerves and vessels. POP is a promising minimally invasive procedure for immediate pain relief. This review provides a technical survey for POPs in painful bony lesions.