• Title/Summary/Keyword: Uterine cervix

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Analysis of Pretreatment Prognostic Factors in Stage IIB Carcinoma of the Uterine Cervix (자궁경부암 IIB 병기에서의 치료전 예후 인자의 분석)

  • Shin, Kyung-Hwan;Ha, Sung-Whan;Yoo, Keun-Young
    • Radiation Oncology Journal
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    • v.10 no.2
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    • pp.227-236
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    • 1992
  • From March 1979 through December 1986, 232 previously untreated patients with invasive carcinoma of the uterine cervix stage IIB were treated at the Department of Therapeutic Radiology, Seoul National University Hospital. The patients studied were staged according to the FIGO recommendations and the majority of patients were treated with external beam whole pelvis radiation and intracavitary radiation. Pretreatment parameters, including physical examination findings, blood parameters, prior medical illnesses, histology and abdomino-pelvic CT findings were studied, employing univariate and multivariate analyses to identify the potentially significant prognostic factors on locoregional control, disease free survival and overall survival. Histology, extent of parametrial involvement on physical examination and paraaortic lymph node metastasis on CT were found to have prognostic significance in the carcinoma of uterine cervix stage IIB.

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Pregnancy-associated changes in morphological and histochemical characteristics of the uterine cervix of the native Korean cattle (한우 자궁경부의 임신경과에 따른 형태학적 및 조직화학적 연구)

  • Park, Guwan-myoung;Yang, Hong-hyun;Paik, Young-ki
    • Korean Journal of Veterinary Research
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    • v.28 no.2
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    • pp.261-270
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    • 1988
  • This study was performed to investigate the effect of gestation on the histological and histochemical changes of the uterine cervix of the native Korean cattle. A total of 110 cows obtained from the Chonhuk abattoir were divided into six groups. The 1st group was of 9 non-pregnant cows and 101 singleton pregnant cows were grouped into 5 groups from pregnant I to pregnant V according to gestation periods by means of crown rump length measures. For light microscopy the tissues were fixed in 10% neutral formalin and processed routinely for paraffin sections The $6{\mu}m$ sections were taken and stained with H-E, Alcian blue pH 1.0, Alcian blue pH 2.5, Alcian blue pH 2.5/PAS, PAS reaction, toluidin blue, and trichrome. The results obtained were as follows: 1. The cervical lengths and widths were increased in relation to advancing gestation. 2. The cervical folds of the pregnant groups were increased and complicated with many branches, and the cervical muscosal epithelia were increased in according to advancing gestation. 3. As advancing gestation, the tunics muscularis of cervix was increased following moderate distribution of fibroblast and vascularity, meanwhile decreased mast cells were found. 4. The cervical mucosubstance was composed of mixed mucopolysaccharides; the acid mucus was increased from the early pregnant state but the neutral mucus was found after pregnant IV, and the mucus was stained deeply in each staining in the fold cavity in according to gestation state.

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High versus Low Dose-Rate Intracavitary Irradiation for Adenocarcinoma of the Uterine Cervix (자궁경부 선암 환자에서 고선량률 강내치료와 저선량률 강내치료의 비교)

  • Kim Woo Chul;Kim Gwi Eon;Chung Eun Ji;Suh Chang Ok;Hong Soon Won;Cho Young Kap;Loh JK
    • Radiation Oncology Journal
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    • v.18 no.1
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    • pp.32-39
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    • 2000
  • Purpose :The incidence of adenocarcinoma of the uterine cervix is low. Traditionally, Low Dose Rate (LDR) brachytherapy has been used as a standard modality in the treatment for patients with carcinoma of the uterine cervix. The purpose of this report is to evaluate the effects of the High dose rate (HDR) brachytherapy in the patients with adenocarcinoma of the uterine cervix compared with the LDR. : From January 1971 to December 1992, 106 patients of adenocarcinoma of uterine cervix were treated with radiation therapy in the Department of Radiation Oncology, Yonsei University with curative intent. LDR brachytherapy was carried out on 35 patients and 71 patients were treated with HDR brachytherapy. In LDR Group, 8 patients were in stage I, 18 in stage II and 9 in stage III. External radiation therapy was delivered with 10 MV X-ray, daily 2 Gy fractionation, total dose 40$\~$46Gy (median 48 Gy). And LDR Radium intracavitary irradiation was peformed with Henschke applicator, 22$\~$59 Gy to point A (median 43 Gy). In HDR Group, there were 16 patients in stage 1, 38 in stage II and 17 in stage III. The total dose of external radiation was 40$\~$61 Gy(median 45 Gy), daily 1.8$\~$2.0 Gy. HDR Co-60 intracavitary irradiation was peformed with RALS (Remote Afterloading System), 30 $\~$ 57 Gy(median 39 Gy) to point A, 3 times a week, 3 Gy per fraction. Conclusion : The 5-year overall survival rate in LDR Group was 72.9$\%$, 61.9$\%$, 45.0$\%$ in stage I, II, III, respectively and corresponding figures for HDR were 87.1$\%$, 58.3$\%$, 41.2$\%$, respectively (p>0.05). There was no statistical difference in terms of the 5-year overall survival rate between HDR Group and LDR Group in adenocarcinoma of the uterine cervix. There was 11$\%$ of late complication rates in LDR Group and 27$\%$ in HDR Group. There were no prognostic factors compared HDR with LDR group. The incidence of the late complication rate in HDR Group stage II, III was higher than that in LDR Group(16.7$\%$ vs. 31.6$\%$ in stage II, 11.1$\%$ vs. 35.3$\%$ In stage III, p>0.05). Although the incidence of radiation induced late complication rate was higher in HDR Group stage II and III patients than that in the LDR Group, statistical significance was not detected and within acceptable level. Conclusion : There was no difference in terms of 5-year survival rate and failure pattern in the patients with adenocarcinoma of the uterine cervix treated with HDR and LDR brachytherapy. Even late complication rates were higher in the HDR group It was an acceptable range. This retrospective study suggests that HDR brachytherapy seems to replace the LDR brachytherapy in the adenocarcinoma of the uterine cervix. However, further studies will be required to refine the dose rate effects.

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Case of Bacterial Identification in Reproductive Organs of Holstein Dairy Cows with Endometritis or Pyometra (자궁내막염 혹은 자궁축농증 발병 젖소의 생식기 내 분포하는 세균 동정 증례)

  • Choe, Changyong;Jung, Young-Hoon;Jo, Yong-Il;Yoo, Jae-Gyu;Im, Seok-Ki;Kwon, Eung-Gi;Seong, Hwan-Hoo;Kim, Sung-Woo;Cho, Young-Moo;Kim, Chang-Woon;Kang, Dawon
    • Journal of Embryo Transfer
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    • v.30 no.3
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    • pp.257-260
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    • 2015
  • Reproductive disorders in cows cause economic loss in livestock farms. Reproductive diseases, such as follicular cyst, luteal cyst, endometritis, pyometra, and repeat breeding cause infertility. Among these diseases, endometritis and pyometra are uterine infections that are leading causes of infertility. This study was performed to investigate the causative agents of uterine diseases using bacterial culture. Bacteria were obtained from the reproductive organs (vagina, uterine cervix, and uterine horn) of dairy cow diagnosed with endometritis or pyometra, and cultured on blood agar. The colonies obtained from cultivation for 24 hours were passaged. To identify the bacteria, the colonies grown in passaged culture Gram stained and applied to an automatic biochemical microbial identification system. Escherichia coli were commonly detected in vagina, uterine cervix, and uterine horn of dairy cows diagnosed to pyometra. The cows having endometritis showed not only Escherichia coli but also Pantoea spp. and Klebsiella spp. strains. Dairy cows that were infected with Escherichia coli in uterus caused mastitis or digestive disease. These results suggest that sanitary feeding and management beforehand are needed to prevent bacterial infections.

Effects of Abdominal Breathing on Anxiety and Labor Time in Primipara Women (복식호흡이 초산부의 진통 중 불안과 분만소요시간에 미치는 효과)

  • An, Sung-Eun
    • Women's Health Nursing
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    • v.14 no.3
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    • pp.196-204
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    • 2008
  • Purpose: This study aimed to examine the effects abdominal breathing on anxiety and length of labor time in primipara women. Method: It was a quasi-experimental design with a non-equivalent comparison group, performed from October 11 to December 4, 2007. Thirty-six subjects who received pitocin and met the inclusion criteria were chosen by convenience sampling from the labor room of Y hospital located in Seoul. The intervention of abdominal breathing was 'four seconds of inhale, six seconds of exhale breathing method.' The abdominal breathing was carried out 30 times each when the uterine cervix was dilated $3{\sim}4cm$ and $5{\sim}6cm$. Psychological anxiety was measured by VAS-A before and after the cervix dilatation to $3{\sim}4cm$ and $5{\sim}6cm$. Result: Anxiety scores of the experimental was found lower than that of the control group at $3{\sim}4cm$(z=-3.05, p=.00) and $5{\sim}6cm$(z=-2.04, p=.04) of cervix dilatation. However, the abdominal breathing was not effective to the length of labor from the active phase thru full dilatation, though there was 56 minutes of difference between the two groups. Conclusion: Carrying out the abdominal breathing 30 times at two time points was effective in decreasing anxiety level during labor. Further study is suggested to examine the effects of abdominal breathing on labor time, fetal heart rate, and uterine contraction.

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A Study on Specificity of Cancer Incidence in Daegu-Kyungbuk Area (일부 지역의 암발생 특성에 관한 조사연구)

  • 김진모;민경진
    • Korean Journal of Health Education and Promotion
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    • v.6 no.1
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    • pp.60-65
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    • 1989
  • A statistical analysis was made on 15,971 surgically operated patients at D-Medical Center in the year of 1978 and 1988. 1,416 cancer patients among them were classified by sex, age, and malignant tumor site. The obtained results indicated that trend of male cancer was generally similar to the results of nation wide study. But, specific phenomenon was found in the case of female cancer in Daegu-Kyungbuk area. Among females the frequency rank was uterine cervix (35.77%), breast (17.97%), stomach (11.65%) in 1988. The frequency of uterine cervix was higher than other area. Breast cancer was highly ranked tumor compare with other area, and its age distribution also appeared in much younger decade.

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Economic Consideration of Mass Screening Program for Early Detection of Carcinoma of the Uterine Cervix (자궁부암의 조기발견을 위한 집단 적격 검사 계획의 경제학적 고려)

  • Yang, Dal-Sun
    • Journal of Preventive Medicine and Public Health
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    • v.7 no.2
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    • pp.367-372
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    • 1974
  • Authors reviewed 2,362 cases of consecutive vaginal and cervical smears submitted to the Department of Pathology, Pusan Gospel Hospital during one year period from Jan. 1, 1974 to Dec. 31, 1974. Prevalence of dysplasia, carcinoma in situ and invasive carcinoma of the uterine cervix was analyzed, and cost per a lesion was calculated. The followings are conclusions: 1. Prevalence of dysplasia, carcinoma in situ and invasive carcinoma was 2.88%, 0.34% and 2.58% restectively. 2. Cost per a lesion for dysplasia was calculated as 34,735 Won, for carcinoma in situ, as 295,250 Won and for invasive carcinoma as 38,721 Won. Cost per a lesion for dysplasia and carcinoma in situ was calculated as 31,079 Won and for dysplasia and for all the lesions as 17,248 Won. 3. The results obtained suggested that mass cytologic screeiding for detection of dysplasia, carcinoma in situ and invasive carcinoma was reasonable in the present status of economy.

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