Most scholars calssify caves into natural resource, but caves possess values of natural and human resource, mix up the features of natural resources and human resources. Now, caves are distributed 260 in Korea. Seongryu Cave is showed in 1967 for the first time, till 1997 12 caves is opened to tourist. But since 1996 the 12 show caves of all is not launched the safety and environment-protection check-up adduced reason for IMF. Then caves must maintain environment of the normal temperature, humidity and dark. But the environment of caves are destroyed by tourism development. Thus to maintain environment of caves, it used to consider the counterplan as follows in restraint of the environmental change. Firstly, in case of development work to open caves, it must keep up with the prototype. Secondly, it must establish a freight depositary to prevent the influence of the caves's stain and damage due to tourist's objects. Thirdly, to maintain the normal temperature and humidity, it must install artificial poultice equipment of the inner parts of caves. Fourthly, in order to prevent the occurrence of $CO_2$, it must assessment of the optimum number of the greatest stayer. Fifthly, the control of closure for a given period of time is useful of the restoration to the cave's original state. Sixthly, by means of make narrow entrance, it should not influence the outer's air on the inner parts on caves. Seventhly, to keep the temperature of the inner part of caves, the lightening should be maintained moderately considering the convenience of a tour. Eightly, when water-proof cables for the lightening bulbs are connected each other, silicon tape is suitable and circuit breakers should be installed at the diverging points of the cables. Ninthly, the direction and angle of the lightening must be changed periodically to prevent green-pollution at the lightening spot. Lastly, when facilities and arrangements are equipped, corrosive materials should be excluded if circumstances allow.
The overproduction of nitric oxide (NO) by inducible nitric oxide synthase (iNOS) is known to be responsible for vasodilation and hypotension observed in septic shock and inflammation. Inhibitors of iNOS, thus, may be useful candidates for the treatment of inflammatory diseases accompanied by overproduction of NO. In the course of screening oriental anti-inflammatory herbs for the inhibitory activity of NO synthesis, a crude methanolic extract of Curcuma zedoaria exhibited significant activity. The activity-guided fractionation and repetitive chromatographic procedures with the EtOAc soluble fraction allowed us to isolate three active compounds. They were identified as 1,7-bis (4-hydroxyphenyl)-1,4,6-heptatrien-3-one (1), procurcumenol (2) and epiprocurcumenol (3) by spectral data analyses. Their concentrations for the 50% inhibition of NO production $(IC_{50})$ in lipopolysaccharide (LPS)-activated macrophages were 8, 75, 77 ${\mu}M$, respectively. Compound 1 showed the most potent inhibitory activity for NO production in LPS-activated macrophages, while the epimeric isomers, compound 2 and 3 showed weak and similar potency. Inhibition of NO synthesis by compound 1 was very weak when activated macrophages were treated with 1 after iNOS induction. In the immunoblot analysis, compound 1 suppressed the expression of iNOS in a dose-dependent manner. In summary, 1,7-bis (4-hydroxyphenyl)-1,4,6-heptatrien-3-one from Curcuma zedoaria inhibited NO production in LPS-activated macrophages through suppression of iNOS expression. These results imply that the traditional use of C. zedoaria rhizome as anti-inflammatory drug may be explained at least in part, by inhibition of NO production.
Korean Journal of Computational Design and Engineering
/
v.20
no.1
/
pp.65-74
/
2015
Structure and/or fluid analysis is gradually increased by an essential design process in the small and medium-sized businesses (SMBs) because of the needs for a rapid design process and the certification about the supplement of the parts by the large business (LB). In this paper, we developed the web-based ezSIM platform installed in the resources integrated system server. The ezSIM platform is based on the heterogeneous linux and windows operating system for the user-friendly connection with the part of the analysis for the SMBs. The procedure of the structure/fluid analysis service module using the public software and the license-free open code in the ezSIM platform was explained. The convenience of the ezSIM platform service was presented by the reaction rate of the graphic motion compared with that of a local PC and the solving and pre-post processing interface compared with that of the KISTI supercomputer. The web-based ezSIM platform service was identified as a useful and essential platform to the SMBs for the usage of the structure and/or fluid analysis procedure.
Lee, Jong Kuk;Kim, Jea Chul;Lee, Kun Jai;Belorid, Miloslav;Beeley, Philip A.;Yun, Jong-Il
Nuclear Engineering and Technology
/
v.46
no.4
/
pp.557-568
/
2014
This paper presents the results of an analysis of wind characteristics and atmosphere dispersion modeling that are based on computational simulation and part of a preliminary study evaluating environmental radiation monitoring system (ERMS) positions within the Barakah nuclear power plant (BNPP). The return period of extreme wind speed was estimated using the Weibull distribution over the life time of the BNPP. In the annual meteorological modeling, the winds from the north and west accounted for more than 90 % of the wind directions. Seasonal effects were not represented. However, a discrepancy in the tendency between daytime and nighttime was observed. Six variations of cesium-137 ($^{137}Cs$) dispersion test were simulated under severe accident condition. The $^{137}Cs$ dispersion was strongly influenced by the direction and speed of the main wind. A virtual receptor was set and calculated for observation of the $^{137}Cs$ movement and accumulation. The results of the surface roughness effect demonstrated that the deposition of $^{137}Cs$ was affected by surface condition. The results of these studies offer useful information for developing environmental radiation monitoring systems (ERMSs) for the BNPP and can be used to assess the environmental effects of new nuclear power plant.
Purpose: This study investigated the effects of proprioceptive neuromuscular facilitation (PNF) exercise on the range of motion (ROM), pain, and functional activity of patients who received total knee arthroplasty (TKA). The purpose of this study was to provide fundamental data regarding the use of PNF exercise among patients with musculoskeletal disease. Methods: Fourteen patients who received TKA were randomly divided into an experimental group (n=7) that took part in PNF exercise and a control group (n=7) that performed general rehabilitation exercise. Both groups performed the respective exercises for 30 minutes, five times a week for 2 weeks. For the measurement of ROM, the range of knee flexion was measured using a clinometer smartphone application. A visual analogue scale (VAS) was used for the measurement of the level of pain. The timed up and go test (TUG) was conducted to measure functional activity. A paired t-test was performed to compare within-group changes before and after the PNF exercise. Differences between the experimental group and control group were analyzed by an independent t-test. For all tests, the level of statistical significance was set at ${\alpha}=0.05$. Results: After the exercise, there was a significant within-group change in VAS and TUG scores in the experimental group and control group (p<0.01). There was also a significant between-group difference in VAS and TUG scores after the intervention (p<0.05). Conclusion: General rehabilitation exercise is commonly applied as a treatment for TKA patients and is relatively effective. The application of PNF exercise may be useful in such patients, considering its effects on ROM improvement, pain reduction, and functional enhancement.
This study focuses on the ideas that Chok-Du-Ri(족두리)ㆍHwa-Gwan(화관) are mentioned a substitute preventing abuses of luxury mood by Gache(가채) as the sharpest social problem at that time. First, the origin of Chok-Du-Ri(족두리) was introduced from Ko-Ko-Gwan(고고관) of Mongo(몽고) in Korea dynasty, then was linked to Chosun. That is, Ko-Ko(고고) started from headgear reflecting spiritual view of the northen people, its size was getting smaller passing through Ming(명) dynasty, its essential decoration changed and it carried out Jeon-Ja(전자) remaining decoration nature by real accessories, then it might be descended to Chosun. Second, Hwa-Gwan(화관) is very different from Nanaec(난액) of Chosun Dynasty Records, rather Jeonia, the original form of Chok-Du-Ri, is more similar to it. Third, its decoration like color, jewel, pattern etc influenced wishes of this life like sex, prosperity, glory, longevity, blessing, wealth and fame. Fourth, Chok-Du-Ri(족두리) was restored a substitute for Gache(가채), it was accessory for preventing luxury life, besides it was modeled from headgear in China, Chosun people had it. It is worthwhile as it was based on Chosun Sinocentrism(조선중화주의) in the latter period of Chosun and made it the fruit of that age. Moreover, in those days Qing(청) society accepted the advanced culture and institutional profit of Qing(청) actually, social mood is that home and overseas policy was corrected in many parts, Chok-Du-RiㆍHwa-Gwan were mentioned a substitute of Gache, symbol of luxury. It shows one part of Practical Thougth that abolishes vanity and affectation and makes useful profits in the latter period of Chosun.
Lines of non-extension (LoNEs) on torso surface during arm abduction were investigated to provide appropriate location for inserting less-extensible yarns which can be used as seams for design and or clothing pressure variation. As experimental methods, reference points about 3 cm apart were marked on the skin and scanned at 30, $90^{\circ}$ and $135^{\circ}$ arm abduction. Skin deformation was measured by connecting reference points in horizontal, vertical and various angles of diagonal directions. Observation of skin deformation was made within the separated sections of the torso as well as integrated ones to cover the various occasions of design application. LoNEs of front and back torso were provided as mapping lines. Actual compression wear of three types was constructed with different pattern reduction rate at each separated section using LoNEs as boundary cutting lines. Clothing pressure and subjective evaluations of those three compression wear were evaluated by six subjects. LoNEs found in this study were useful as seam lines to differentiate clothing pressure at each part of the body, providing positive wear sensation. It is also expected that LoNEs can be paths for less strechable conductive yarns of IT-integrated upper garments.
This study is to investigate the housing conditions and housing satisfaction of Chinese students in S. Korea, and identified effective factors for related housing design. Chinese students at CBNU participated in this survey from November to December in 2011. A questionnaire survey was used. 200 students voluntarily participated in this survey with 147 surveys providing useful data for analysis. Descriptive statistics, correlation, and linear regression were used to analyzed the data with SPSS 12.0. The results are as follow. 1) Many Chinese students received housing information from discussion with acquaintance. They lived together 2 students in one-room or dormitory. Monthly rental was about 240,000 won, and they found the living conditions a burden. 2) They are unsatisfied with food, the lack of a refrigerator, and non availability kitchen facilities. These factors are considered in planning for Chinese students housing. 3) For the most part, they are satisfied with their current housing environment, although there is a need to improve health related housing environment factors, including sunlight, noise, and indoor air. The effective residential factors to overall housing satisfaction are dwelling space and size, space organization and floor plan, kitchen toilet bathroom facilities, sunlight, and safety from natural disasters. The effective neighborhood factors identified include access to natural environment, community facilities, parks, noise, and commuting time. 4) Subjective factors played a larger role in overall housing satisfaction than did objective factors such as gender and types of house.
The last few years have been a boom time for the online gaming industry. Internet-based online games have made an increasingly popular form of entertainment. The gaming industry estimates that online gaming players reach over 26 million in 2002. The rapid development of online game-contents and related information technology shall increase the size of industry and have a profound impact on many ways of our living and sociaty. This paper develops the exploratory LISREL model for identifying the factors attecting the players' loyalty for some specific brand of online games. The concept of flow, word of mouth, feedback, challenge, social norms, and online community activities, etc, are all introduced into the model, as the independent variables affecting the loyalty directly and indirectly. Based on data collected from online questionnaire survey, the validity of the model has been tested and interesting conclusions have been developed concerning the relationships between the loyalty, flow, word of mouth and other set of independent vareables. It is hoped that this result might provide the useful guidelines for developing the successful online game contents.
Purpose: The purpose of study was to identify how patients experienced chemotherapy-induced peripheral neuropathy (CIPN) and quality of life related to CIPN. Methods: This was a descriptive research. We collected data from 105 patients with chemotherapy-induced peripheral neuropathy. They completed a self-reported questionnaire including Eastern Cooperative Oncology Group (EORTC) CIPN20 and items related to their disease and peripheral neuropathy. The investigators filled in part of items about disease and treatment. Results: In the study, duration of peripheral neuropathy was 9.4 month and 54.3% of patients used pharmacological or non-pharmacological interventions. Patients reported the highest score for sensory scale and it's score was $38.74{\pm}20.24$. The scores for motor scale and autonomic scale were $21.95{\pm}19.19$ and $26.61{\pm}21.0$ respectively. This showed that patients more suffered from sensory neuropathy than any other domain of neuropathy. The most frequently selected two items were 'did you have tingling fingers or hands?' and 'did you have tingling toes or feet?'. Conclusion: The results of this study will provide useful information for chemotherapy-induced peripheral neuropathy.
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