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Revisit to Unfulfilled Premise of Arylsulfonylimidazolidinones as Anticancer Agent

  • Hung, Dang-The;Lee, Jee-Hyun;Cho, Soo-Hyun;Hong, Chang-Yong;Jeong, Shin-Wu;Jeon , Ki-Wan;Lee, Sung-Bae;Choi, Whan-Geun;Jung, Sang-Hun
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.344.3-345
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    • 2002
  • For the development of novel anticancer agent. we have designed. synthesized. and tested novel 4-phenyl-1(N)-arylsulfonylimidazolidinones. As a result. much more potent cytotoxicities of these compounds against the various cancer cell lines than those of doxorubicin were demonstrated. Elaboration on aryl motif on sulfonyl moiety led us to find highly potent 4-phenyl-1-(N-acylindoline-5-sulfonyl)imidazolidinones. Among them, 4-phenyl-l- [N-(p-aminobenzoyl)indoline-5-sulfonyl]imidazolidinone (PA) was proved to have good pharmacological profile. (omitted)

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RESOLVENT INEQUALITY OF LAPLACIAN IN BESOV SPACES

  • Han, Hyuk;Pak, Hee Chul
    • Journal of the Chungcheong Mathematical Society
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    • v.22 no.1
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    • pp.117-121
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    • 2009
  • For $1{\leq}p$, $q{\leq}{\infty}$ and $s{\in}\mathbb{R}$, it is proved that there exists a constant C > 0 such that for any $f{\in}B^{s+2}_{p,q}(\mathbb{R}^n)$ $${\parallel}f{\parallel}_{B^{s+2}_{p,q}(\mathbb{R}^n)}{\leq}C{\parallel}f\;-\;{\Delta}f{\parallel}_{B^{s}_{p,q}(\mathbb{R}^n)}$$, which tells us that the operator $I-\Delta$ is $B^{s+2}_{p,q}$-coercive on the Besov space $B^s_{p,q}$.

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DEPTHS OF THE REES ALGEBRAS AND THE ASSOCIATED GRADED RINGS

  • Kim, Mee-Kyoung
    • Bulletin of the Korean Mathematical Society
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    • v.31 no.2
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    • pp.210-214
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    • 1994
  • The purpose of this paper is to investigate the relationship between the depths of the Rees algebra R[It] and the associated graded ring g $r_{I}$(R) of an ideal I in a local ring (R,m) of dim(R) > 0. The relationship between the Cohen-Macaulayness of these two rings has been studied extensively. Let (R, m) be a local ring and I an ideal of R. An ideal J contained in I is called a reduction of I if J $I^{n}$ = $I^{n+1}$ for some integer n.geq.0. A reduction J of I is called a minimal reduction of I. The reduction number of I with respect to J is defined by (Fig.) S. Goto and Y.Shimoda characterized the Cohen-Macaulay property of the Rees algebra of the maximal ideal of a Cohen-Macaulay local ring in terms of the Cohen-Macaulay property of the associated graded ring of the maximal ideal and the reduction number of that maximal ideal. Let us state their theorem.m.m.

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Polarity Control of Wurtzite Crystal by Interface Engineering (계면공학에 기초한 우르차이트 결정의 극성 조절)

  • Hong, Soon-Ku;Suzuki, Takuma;;Cho, Myung-Whan;Yao, Takafumi
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2005.11a
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    • pp.95-96
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    • 2005
  • The general method and mechanism for the polarity control of heteroepitaxial wurtzite films, such as ZnO and GaN, by interface engineering via plasma-assisted molecular beam epitaxy are addressed. We proposed the principle and method controlling the crystal polarity of ZnO on GaN and GaN on ZnO. The crystal polarity of the lower film was maintained by forming a heterointerfce without any interface layer between the upper and the lower layers. However the crystal polarity could be changed by forming the heterointerface with the interface layer having an inversion center. The principle and method suggested here give us a promising tool to fabricate polarity inverted heterostructures, which applicable to invent novel heterostructures and devices.

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Pollutant Removal Efficiency in Oxidation Pond with Filamentous Algae Mat (사상성 조류매트 산화지의 수질정화효율)

  • Choi, Sun-Hwa;Jang, Jeong-Ryeol;Ahn, Yeul
    • Proceedings of the Korean Society of Agricultural Engineers Conference
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    • 2005.10a
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    • pp.655-660
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    • 2005
  • This study was carried out to evaluate of water purification in oxidation pond with filamentous algae mat. It is the water treatment process in the small rural streams to remove the organic materials and nutrients. We used the filamentous algae mat(FAM) which selectively predominate the filamentous algae to prevent the additional contamination by algae outflow. The removal efficiencies of COD, SS, T-N and T-P in Oxidation Pond with Filamentous Algae Mat were -2.5%, 84.7%, 63.9% and 89.2%, respectively. The removal efficiencies of T-N and T-P which are nutrients index were high. Results of this study would help us to determine the possibility of using the water treatment on the contaminated small rural streams.

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Crystallographic, Magnetic and Mössbauer Study of Phase Transition in LaVO3

  • Yoon, Sung-Hyun
    • Journal of Magnetics
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    • v.12 no.3
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    • pp.108-112
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    • 2007
  • Nature of phase transition in $LaVO_3$ has been studied using X-ray diffraction, SQUID magnetometer, and $M\"{o}ssbauer$ spectroscopy with 1% of $^{57}Fe$ doped sample. The crystal structure was orthorhombic with space group Pnma. Antiferromagnetic phase transition temperature $T_N$ was 140K, below which a weak ferromagnetic trace has been found. $M\"{o}ssbauer$ spectra below $T_N$ were single set of hyperfine sextet, which enabled us to discard the possibility of two inequivalent magnetic sites or uncompensated antiferromagnetism. Hyperfine magnetic field abruptly disappeared as low as about 90K, much below $T_N$.

An improvement for system identification by use of M-transform

  • Kashiwagi, H.;Liu, M.;Harada, H.;Yamaguchi, T.
    • 제어로봇시스템학회:학술대회논문집
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    • 1998.10a
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    • pp.275-279
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    • 1998
  • In this paper, the authors propose a new method for improving identification method of linear system by us-ing M-transform. The authors has recently proposed a new mettled for linear system identification by use of M-transform. In this method, the input signal n(i) must have the same period N as that of the M-sequence. When N becomes large, it will take a long time to compute. To overcome this difficulty, we propose a new approach of system identification by using a small size matrix. The results of simulation show a good agreement with the theoretical considerations.

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Study on 4,4-pentamethylene-1,3-oxazolidine-5-one-2-thione (4,4-pentamethylene-1,3-oxazolidine-5-one-2-thione에 관한 연구)

  • 국채호;조윤상;주상섭
    • YAKHAK HOEJI
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    • v.16 no.2
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    • pp.85-89
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    • 1972
  • 4,4-Pentamethylene-1,3-oxazolidine-5-one-2-thione is to be obtained from 1-amino cyclohexane carboxylic acid and thiophosgene, however, it was not isolated because of its unstability. When it was treated with $C_{6}H_{5}NH_{2},$ N-phenyl-(1-aminocyclohexane) carboxylic acid and N-(1-carboxycyclohexyl), N-phenyl thiourea were obtained. When refluxed in $H_{2}O$ at pH 2, pH 12 and neutral condition, the resulting carboxylic compound, being anticipated by us, was 1-aminocyclohexane carboxylic acid. From the above results, we have got the suggestion f the chemical behavior of 4,4-pentamethylene-1,3-oxazolidine-5-one-2-thione and also some informations of the reaction mechanism between 1-aminocyclohexane carboxylic acid and thiophosgene.

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Mathematical Modelling of the H1N1 Influenza (신종 인플루엔자의 수학적 모델링)

  • Lee, Sang-Gu;Ko, Rae-Young;Lee, Jae-Hwa
    • Communications of Mathematical Education
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    • v.24 no.4
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    • pp.877-889
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    • 2010
  • Mathematical modelling is a useful method for reinterpreting the real world and for solving real problems. In this paper, we introduced a theory on mathematical modelling. Further, we developed a mathematical model of the H1N1 influenza with Excel. Then, we analyzed the model which tells us what role it can play in an appropriate prediction of the future and in the decision of accompanied policies.

Faults detection and identification for gas turbine using DNN and LLM

  • Oliaee, Seyyed Mohammad Emad;Teshnehlab, Mohammad;Shoorehdeli, Mahdi Aliyari
    • Smart Structures and Systems
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    • v.23 no.4
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    • pp.393-403
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    • 2019
  • Applying more features gives us better accuracy in modeling; however, increasing the inputs causes the curse of dimensions. In this paper, a new structure has been proposed for fault detecting and identifying (FDI) of high-dimensional systems. This structure consist of two structure. The first part includes Auto-Encoders (AE) as Deep Neural Networks (DNNs) to produce feature engineering process and summarize the features. The second part consists of the Local Model Networks (LMNs) with LOcally LInear MOdel Tree (LOLIMOT) algorithm to model outputs (multiple models). The fault detection is based on these multiple models. Hence the residuals generated by comparing the system output and multiple models have been used to alarm the faults. To show the effectiveness of the proposed structure, it is tested on single-shaft industrial gas turbine prototype model. Finally, a brief comparison between the simulated results and several related works is presented and the well performance of the proposed structure has been illustrated.