• Food Science and Industry
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• v.52 no.2
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• pp.171-187
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• 2019

Novel food materials can be produced based on biotechnology such as genetic recombination, microbial fermentation, and enzymatic engineering by utilizing living organisms such as animal, plant, and microorganism or by applying the enzymes isolated from them. Especially, exploration and development of novel prebiotics and probiotics attracted great attention worldwide in the food industry, of which the research and industrial trends in food biotechnology field are promoting the production of next generation sweeteners and proliferation of beneficial bacteria in gastrointestinal tract. Development and commercialization of novel food materials by domestic bioprocessing technology have been sluggish due to the GMO/LMO food safety issues. Meanwhile, the US and EU do not perceive badly about gene manipulation technology, and the research is most active in the fields of crops and GMMs, respectively. Genetic scissors, which are considered as next generation technology, are notable since foreign genes do not remain in final products.

• Management & Information Systems Review
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• v.28 no.3
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• pp.161-189
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• 2009

The sub-prime crisis led to the collapse of US investment banks which were considered highly competitive during the Asian Financial Crisis. The event gave us a lesson on importance of the financial supervision. Additionally concerns rise over the fact that the role model of the Capital Market Law, created for the purpose of developing the capital market, is the US investment banks. This paper investigates if the prudential regulations, among them especially the capital regulation, are able to prevent the risk the arises from Korean financial firms operating investment bank business. The current capital requirement regulation, Net Capital Ratio(NCR), is not sufficient, because it's nature of being a ratio makes the NCR ineffective when assets and liabilities are concurrently rising. We also verified the internal model which measured the market risk, by comparing the US investment and Korean banks' diversification effect. The result of the test is that it is difficult to conclude the internal model has a critical defect. This paper's contribution is that it is not sufficient use only the capital regulation in supervising financial markets.

• Journal of Korea Technology Innovation Society
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• v.8 no.1
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• pp.220-236
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• 2005

In today's R&D environment, as the complexity of IT systems increases and the expected quality level for R&D outcomes enlarges, it has been critical issues for us to effectively define and improve the R&D standard processes tailored for our organization and projects. To meet this needs, we defined the R&D standard processes based on the international standards for systems and software engineering and our existing traditional work methods, and then applied them of our ongoing projects. Now, we are improving our defined R&D standard processes continuously by monitoring of the processes and products and through the feedback of the application results. In this paper, we introduce the R&D standard process model developed by our organization (E research Institute in Korea) and the requirements and approaches used for their development and improvement. We compare our defined R&D standard processes with ISO/IEC 15288 which is the international standards for systems engineering and summarize the lessons learned through their development and improvement.

• Plant Biotechnology Reports
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• v.3 no.2
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• pp.157-165
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• 2009

Human erythropoietin (EPO) is a leading product in the biopharmaceutical market, but functional EPO has only been produced in mammalian cells, which limits its application and drives up the production costs. Using plants to produce human proteins may be an alternative way to reduce the cost. However, a recent report demonstrated that overexpression of the human EPO gene (EPO) in tobacco or Arabidopsis rendered males sterile and retarded vegetative growth, which raises concern whether EPO might interfere with hormone levels in transgenic plants. In the present study, we demonstrated that overexpressing EPO with additional 5'-His tag and 3' ER-retention peptides in tobacco did not cause any developmental defect compared to GUS plants. With our method, all 20 transgenic plants grew on selective medium and, further confirmed by PCR, were fertile. Most of them grew similarly compared to GUS plants. Only one transgenic plant (EPO2) was shorter in plant height but had twice the life span compared to other transgenic plants. When 11 randomly selected EPO plants, along with the abnormal plant EPO2, were subjected to RT-PCR analysis, all of them had detectable EPO transcripts. However, their protein levels varied considerably; seven of them had detectable EPO proteins analyzed by western blot. Our results indicate that overexpressing human EPO protein in plants does not have detrimental effects on growth and development. Our transformation systems allow us to further explore the possibility of glycoengineering tobacco plants for producing functional EPO and its derivatives.

• Korean Journal of Health Education and Promotion
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• v.1 no.1
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• pp.43-57
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• 1999

One of the most fundamental and the oldest issues in the provision of health care throughout the world has been the issue of the role of the public and private sector of health care, and the relationship between them. This paper describes issues associated with the concept of health oriented partnerships in the United Kingdom and seeks to contrast public and private partnerships both in health and in health care. In the United Kingdom it is suggested that health care is conceived by the population to equate to the National Health Service(NHS) with "add on" private health care for certain sectors of the community and within certain well defined clinical parameters. This paper can provide us with valuable information on the characteristics of UK health care systems, current health policies as well as issues relating to the public and private partnerships in health/ health care in the UK, thus offer important policy implications for the improvement of Korean health care system which lacks health-oriented coordinations and partnership between public and private sector very considerably.

• Proceedings of the KSPS conference
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• 2005.04a
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• pp.71-75
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• 2005

We can easily recognize the voices already known to us. But what about unknown voices? Is there any relationship between voices and the images triggered by the voices? Actually, this question has been partly addressed by Moon(2000, 2002). The current study aims at shedding some more lights on the topic by investigating the relationship between unknown foreign voices and the images triggered by them. Speech samples from 16 American males and females (8 each) were recorded and 180 Korean subjects without any knowledge of the American Speakers were asked to match the voices with the corresponding photos. And the number of corrects matches between voices and pictures of the current study was less than that of Korean-speakers and Korean-listeners case. But in terms of the majority matches, regardless of correctness, the present study showed a similar trend: that is, there is more than a chance relationship between voices and the images triggered by the voices.

• Journal of Korea Society of Digital Industry and Information Management
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• v.10 no.3
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• pp.23-33
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• 2014

The smart phone are changing the way people communicate. And, the mobile app marketplace is greatly fast-growing. The app store continues its rapid growth, there are already more than 900,000 mobile apps on AppStore. We anticipate to see gained momentum throughout the business. Mobile is also becoming popular for marketers. Therefore, specialized app analysis systems are becoming important to how marketers and app developers invest, analyze and market their apps. App analysis systems enable users to discover and analyze behavior through data observations and meaningful patterns. In this paper, we introduce app analysis system and CMS System Open API, NugaLog. The NugaLog acquires users data and engages with them in a variety of ways. It will be essential for us to understand how users interact with and move through the app. The NugaLog will be able to see the number of users, smart phone model, smart phone OS, resolution, page views, and app version.

• Journal of the Korean Mathematical Society
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• v.54 no.5
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• pp.1457-1482
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• 2017

Let S and R be rings and $_SC_R$ a (faithfully) semidualizing bimodule. We introduce and study C-weak flat and C-weak injective modules as a generalization of C-flat and C-injective modules ([21]) respectively, and use them to provide additional information concerning the important Foxby equivalence between the subclasses of the Auslander class ${\mathcal{A}}_C$ (R) and that of the Bass class ${\mathcal{B}}_C$ (S). Then we study the stability of Auslander and Bass classes, which enables us to give some alternative characterizations of the modules in ${\mathcal{A}}_C$ (R) and ${\mathcal{B}}_C$ (S). Finally we consider an open question which is closely relative to the main results ([11]), and discuss the relationship between the Bass class ${\mathcal{B}}_C$(S) and the class of Gorenstein injective modules.

• Korean Journal of Child Studies
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• v.3
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• pp.115-126
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• 1982

Nobody denies that to detect a view of children agreeable to us is one of our tasks. Studying the Early Buddhist Scriptures, for the purpose of finding and the view of children entered the priesthood of Buddhism rooted deeply in our culture, I can find out the following conclusions. 1. Buddha regards that adults and children are same in that both of them are equally able to attain Nirvana, and he recognizes the differences between adults and children appeared in body and mind in the process of spiritual discipline. 2. He consideres that parent's worldly love is needed to the children priests below the age of 12. 3. He called priests over the age of 12 to 20 children priests, and he said that they have to be under a certain guard in particular, because unlike adults they have a lot of problem in the discipline process. 4. In the view of human being's growth and development, it is assumed that the group of children priests played a part as a group of spiritual discipline for youths. 5. It's regarded that the group of children priests also had function as a group of child welfare of today. 6. In other side, we can see Buddha's strict view of education for children priests, that is, even though they were children they had to discipline themselves thoroughly according to the view of values of Buddhism as far as they are priests who entered the temple. 7. Even if they are children, only minimal living things are permitted to them, and an ascetic life is required to them. In modern sense, how can such views be accepted and used? I think, this is our new task deeply looked into again in the standpoint of education of whole man rooted in religions psychology.

• BMB Reports
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• v.57 no.5
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• pp.216-231
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• 2024

Mammalian genomes are intricately compacted to form sophisticated 3-dimensional structures within the tiny nucleus, so called 3D genome folding. Despite their shapes reminiscent of an entangled yarn, the rapid development of molecular and next-generation sequencing technologies (NGS) has revealed that mammalian genomes are highly organized in a hierarchical order that delicately affects transcription activities. An increasing amount of evidence suggests that 3D genome folding is implicated in diseases, giving us a clue on how to identify novel therapeutic approaches. In this review, we will study what 3D genome folding means in epigenetics, what types of 3D genome structures there are, how they are formed, and how the technologies have developed to explore them. We will also discuss the pathological implications of 3D genome folding. Finally, we will discuss how to leverage 3D genome folding and engineering for future studies.