• Title/Summary/Keyword: Urinary Tract

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Use of selegiline in 3 Cases of Canine Pituitary-dependent Hyperadrenocorticism (개의 뇌하수체 의존성 부신 피질 기능 항진증에서의 selegiline 적용)

  • 김주민;황철용;윤정희;윤화영;한홍율
    • Journal of Veterinary Clinics
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    • v.19 no.4
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    • pp.455-460
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    • 2002
  • Pituitary-dependent hyperadrenocorticism (PDH) was diagnosed with history taking, physical examination, complete blood count, serum chemistry profiles, abdominal radiology, ultrasonography and adrenal function tests in 3 dogs. Their clinical signs were polyuria, polydipsia, polyphagia, bilateral symmetrical truncal alopecia and secondary infection in skin or urinary tract. Especially one dog showed severe clinical signs such as calcinosis cutis and delayed wound healing. These 3 dogs were diagnosed as PDH, and treated with selegiline 1-2 mg/kg /ay sid PO. 2 dogs with clinical signs of PDH were disappeared and improved, but 1 dog with severe illness progressed gradually despite of selegiline and mitotane application, and eventually died.

Analysis of Basic Constituents in Korean Earthworm About Lamnodrilus gotai Hatai (한국산 토룡의 기초성분 분석 -Lamnodrilus gotai Hatai를 대상으로-)

  • Chung, Yong;Lee, Yun-Sil;Lee, Hyo-Min
    • YAKHAK HOEJI
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    • v.31 no.4
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    • pp.224-229
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    • 1987
  • The earthworm(Annelid) is a herbicine which has traditionally been used in the treatment of infectious fever, jaundice, infection of middle ear, laryngitis, pharyngitis, nephritis, headache, toothache and certain urinary tract infections from the olden times. Before the isolation and purification of biologically active components we analyzed the basic constituents(proteins, amino acids, mineral, etc.) with lyophilized powder of Lamnodrilus gotai Hatai. The results were as follows: Minerals detected and quantitatively analyzed were $Ca^#$, $Mg^#$, Fe, Zn, Mn, Cu, Co, Cr, Ni, Ge and Se. Amino acids detected were alanine, phenylalanine, leucine, glutamic acid, tyrosine, threonine, arginine, aspartic acid, methionine, lysine, serine, histidine, isoleucine, glycine, proline and etc. The constituents of proteins, fat, fiber, ash and phosphorous were measured. These constituents were compared and discussed with those of other investigations.

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Short Term Antibiotic Prophylaxis in Open Heart Surgery (개심술시 단기적인 예방적 항생제 투여요법에 관한 연구)

  • 이건우
    • Journal of Chest Surgery
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    • v.18 no.4
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    • pp.740-745
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    • 1985
  • A retrospective double blind study comparing 7 day with 2 day regimen of antibiotic prophylaxis was conducted among 200 patients undergoing open heart surgery. No case of endocarditis and wound infection occurred. Pneumonia developed in 5 cases of the 7 day and 1 case of the 2 day group. Urinary tract infection without clinical significance developed in 1 case of the 7 day and 3 cases of the 2 day group. Bacteremia developed in 2 cases of the 7 day and 1 case of the 2 day group. We concluded as follows: l. Administration of antibiotics for 2 days appears to be without substantial risk of infection comparing long term 7 day regimen. 2. 7 days of antibiotics may actually increase the risk of serious infection such as nosocomial pneumonia, and predispose to the development of infections with fungi or antibiotic resistant bacteria. 3. 2 days of prophylaxis is more beneficial than long term 7 day regimen for example economically.

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Studies on the patho-physiological observation of lower urinary tract disease of cats (고양이 하부뇨로(下部尿路) 질환(疾患)의 병태생리(病態生理)에 관한 연구(硏究))

  • Shin, Sa-kyeng;Sato, Motoyoshi;Miyahara, Kazuro;Hirose, Tsuneo
    • Korean Journal of Veterinary Research
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    • v.36 no.4
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    • pp.967-972
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    • 1996
  • A study was carried on histopathology of LUTD. Based on this study, it was noted that a plural number of factors and some genetic mechanisms are participating in onset of this disease, which should have to be studied further in future in omnidirections.

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A 13 Week Subcutaneous Toxicity Study of Recombinant Human Epidermal Growth Factor (DWP401) in Mice (Recombinant Human Epidermal Growth Factor (DWP401)의 마우스를 이용한 피하투여 아급성독성시험)

  • 송시환;강부현;신천철;김희연;강진석;심점순;한상섭;노정구
    • Biomolecules & Therapeutics
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    • v.4 no.2
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    • pp.138-147
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    • 1996
  • DWP401, a recombinant human epidermal growth factor, was subcutaneously administered to ICR mice at the dose levels of 0, 0.04, 0.2 and 1.0 mg/kg/day (15rats/sex/group) in order to evaluate the subchronic toxicity. General observations, examinations for food and water consumption, ophthalmoscopy and urinalysis were carried out during the study. For the complete gross and microscopic examinations, 10 mice/ sex/group were sacrificed at the ends of the dosing period, and the remaining animals were sacrificed with a 5 week recovery period. Examinations for hematology and blood biochemistry were also carried out at the time of recovery period. Based on the results, it was thought that the target tissue or organs were mesothelial cell, injection site, spleen, adrenal gland, ovary and transitional epithelial cell of urinary tract, and no observed toxic level of DWP401 was 0.04 mg/kg while definite toxic dose level might be 0.2 mg/kg.

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Prenatally Diagnosed and Surviving Patient with Jarcho-Levin Syndrome: Case Report with Literature Review

  • Lee, Chan Young;Lee, Na Mi;Yi, Dae Yong;Yun, Sin Weon;Chae, Soo Ahn;Lim, In Seok;Kim, Gwang Jun
    • Perinatology
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    • v.29 no.4
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    • pp.185-188
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    • 2018
  • Jarcho-Levin syndrome is a congenital disorder characterized by several vertebral and costal anomalies. Other abnormalities have also been described, including neural tube defects, Arnold-Chiari malformation, renal/urinary tract abnormalities, hydrocephalus, hydroureteronephrosis, and meningomyelocele. We describe a spondylocostal dysplasia form of Jarcho-Levin syndrome that was prenatally diagnosed at 11 weeks of gestation and surviving. Although the patient had sporadic-type Jarcho-Levin syndrome, with normal karyotype and no family history of disease, the assessment of inheritance patterns and genetic counseling for the parents was important to inform them about the potential risks.

A Case Report of Recurrent Cystitis Treated by Baektong-tang based on Shanghanlun Provisions (『상한론(傷寒論)』 변병진단체계(辨病診斷體系)에 근거하여 백통탕(白通湯) 투여 후 호전된 재발성 방광염 증례 1례)

  • Ryu, Hee-chang
    • 대한상한금궤의학회지
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    • v.12 no.1
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    • pp.161-169
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    • 2020
  • Objective: This case report describes the improvements of a patient with recurrent cystitis who was treated using an herbal medication according to the Shanghanlun disease pattern identification diagnostic system (DPIDS). Methods: 'DPIDS'and 'Interpretation based on Etymological chinese characters,'the patient was diagnosed with Shaoyin-bing, provision number 315, and administered Baektong-tang herb medication for 30 days. The changes in the symptoms of recurrent cystitis were estimated using the Interstitial Cystitis Symptom Index and Problem Index-Korean version (ICSI/ICPI-K) and Visual Analogue Scale (VAS). Results : The ICSI/ICPI-K score changed from 33 to 0 and VAS score changed from 7 to 0. Conclusions: The main causes of the disease were 微 and 利,and the symptoms of recurrent cystitis

Clinical Genetic Testing in Children with Kidney Disease

  • Kang, Eungu;Lee, Beom Hee
    • Childhood Kidney Diseases
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    • v.25 no.1
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    • pp.14-21
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    • 2021
  • Chronic kidney disease, the presence of structural and functional abnormalities in the kidneys, is associated with a lower quality of life and increased morbidity and mortality in children. Genetic etiologies account for a substantial proportion of pediatric chronic kidney disease. With recent advances in genetic testing techniques, an increasing number of genetic causes of kidney disease continue to be found. Genetic testing is recommended in children with steroid-resistant nephrotic syndrome, congenital malformations of the kidney and urinary tract, cystic disease, or kidney disease with extrarenal manifestations. Diagnostic yields differ according to the category of clinical diagnosis and the choice of test. Here, we review the characteristics of genetic testing modalities and the implications of genetic testing in clinical genetic diagnostics.

Vesicoureteral reflux-associated hydronephrosis in a dialysis patient treated with percutaneous nephrostomy

  • Ju Hwan Oh;Min Woo Kim;Jung Hwa Kim;A Young Cho;In O Sun;Kwang Young Lee
    • Journal of Medicine and Life Science
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    • v.19 no.2
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    • pp.66-69
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    • 2022
  • Patients with vesicoureteral reflux (VUR), the retrograde flow of urine from the bladder to the kidney, are known to experience renal scarring; this results in the worsening of renal function. Reflux nephropathy is a cause of chronic kidney disease, and VUR has also been observed in dialysis patients. VUR is a major underlying precursor condition of urinary tract infection (UTI) and is sometimes accompanied by hydronephrosis. However, there are no guidelines for the management of UTI due to VUR-associated hydronephrosis in patients with end-stage kidney disease. Herein, we report a case of UTI caused by VUR-associated hydronephrosis in a dialysis patient treated with percutaneous nephrostomy.