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Asymptomatic Human Paragonimiasis among the Karen People in Tak Province, Thailand: A Case Report

  • Kusolsuk, Teera;Phuphisut, Orawan;Maipanich, Wanna;Pubampen, Somchit;Sa-nguankiat, Surapol;Poodeepiyasawat, Akkarin;Homsuwan, Nirundorn;Mongkolmoo, Srisuchart;Yoonuan, Tippayarat;Adisakwattana, Poom;Silachamroon, Udomsak;Nawa, Yukifumi
    • Parasites, Hosts and Diseases
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    • v.58 no.1
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    • pp.57-60
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    • 2020
  • During the mobile clinic activities in Tak Province, Thailand, Paragonimus sp. eggs were found in a fecal sample of a 72-year-old Karen resident. Paragonimus DNA was amplified from the stool sample and identified to P. heterotremus. The patient did not have any symptoms. Apparent pulmonary lesion was not found on the chest X-ray. The patient admitted habitual consumption of semi-cooked or roasted waterfall crabs for several years. The waterfall crabs collected from stream near the village were found negative for Paragonimus metacercariae. In northern Thailand, paragonimiasis remains as one of the public health concerns and should be ruled out for asymptomatic pulmonary patients.

Genome-wide SNP analysis provides insights into the XX/XY sex-determination system in silver barb (Barbonymus gonionotus)

  • Visarut Chailertrit;Thitipong Panthum;Lalida Kongkaew;Piangjai Chalermwong;Worapong Singchat;Syed Farhan Ahmad;Ekaphan Kraichak;Narongrit Muangmai;Prateep Duengkae;Surin Peyachoknagul;Kyudong Han;Kornsorn Srikulnath
    • Genomics & Informatics
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    • v.21 no.4
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    • pp.47.1-47.12
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    • 2023
  • Silver barb (Barbonymus gonionotus) is among the most economically important freshwater fish species in Thailand. It ranks fourth in economic value and third in production weight for fisheries and culture in Thailand. An XX/XY sex-determination system based on gynogenesis was previously reported for this fish. In this study, the molecular basis underlying the sex-determination system was further investigated. Genome-wide single-nucleotide polymorphism data were generated for 32 captive-bred silver barb individuals, previously scored by phenotypic sex, to identify sex-linked regions associated with sex determination. Sixty-three male-linked loci, indicating putative XY chromosomes, were identified. Male-specific loci were not observed, which indicates that the putative Y chromosome is young and the sex determination region is cryptic. A homology search revealed that most male-linked loci were homologous to the Mariner/Tc1 and Gypsy transposable elements and are probably the remnants of an initial accumulation of repeats on the Y chromosome from the early stages of sex chromosome differentiation. This research provides convincing insights into the mechanism of sex determination and reveals the potential sex determination regions in silver barb. The study provides the basic data necessary for increasing the commercial value of silver barbs through genetic improvements.

Management of aerosol generation during upper gastrointestinal endoscopy

  • Chawisa Nampoolsuksan;Vitoon Chinswangwatanakul;Asada Methasate;Jirawat Swangsri;Atthaphorn Trakarnsanga;Chainarong Phalanusitthepha;Thammawat Parakonthun;Voraboot Taweerutchana;Nicha Srisuworanan;Tharathorn Suwatthanarak;Thikhamporn Tawantanakorn;Thawatchai Akaraviputh
    • Clinical Endoscopy
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    • v.55 no.5
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    • pp.588-593
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    • 2022
  • In the highly contagious coronavirus disease 2019 pandemic, aerosol-generating procedures (AGPs) are associated with high-risk of transmission. Upper gastrointestinal endoscopy is a procedure with the potential to cause dissemination of bodily fluids. At present, there is no consensus that endoscopy is defined as an AGP. This review discusses the current evidence on this topic with additional management. Prevailing publications on coronavirus related to upper gastrointestinal endoscopy and aerosolization from the PubMed and Scopus databases were searched and reviewed. Comparative quantitative analyses showed a significant elevation of particle numbers, implying that aerosols were generated by upper gastrointestinal endoscopy. The associated source events have also been reported. To reduce the dispersion, certain protective measures have been developed. Endoscopic unit protocols are recommended for the concerned personnel. Therefore, upper gastrointestinal endoscopy should be classified as an AGP. Proper practices should be adopted by healthcare workers and patients.