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Aerosol protection using modified N95 respirator during upper gastrointestinal endoscopy: a randomized controlled trial

  • Chawisa Nampoolsuksan;Thawatchai Akaraviputh;Asada Methasate;Jirawat Swangsri;Atthaphorn Trakarnsanga;Chainarong Phalanusitthepha;Thammawat Parakonthun;Voraboot Taweerutchana;Nicha Srisuworanan;Tharathorn Suwatthanarak;Thikhamporn Tawantanakorn;Varut Lohsiriwat;Vitoon Chinswangwatanakul
    • Clinical Endoscopy
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    • v.57 no.3
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    • pp.335-341
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    • 2024
  • Background/Aims: The coronavirus disease 2019 pandemic has affected the worldwide practice of upper gastrointestinal endoscopy. Here we designed a modified N95 respirator with a channel for endoscope insertion and evaluated its efficacy in upper gastrointestinal endoscopy. Methods: Thirty patients scheduled for upper gastrointestinal endoscopy were randomized into the modified N95 (n=15) or control (n=15) group. The mask was placed on the patient after anesthesia administration and particles were counted every minute before (baseline) and during the procedure by a TSI AeroTrak particle counter (9306-04; TSI Inc.) and categorized by size (0.3, 0.5, 1, 3, 5, and 10 ㎛). Differences in particle counts between time points were recorded. Results: During the procedure, the modified N95 group displayed significantly smaller overall particle sizes than the control group (median [interquartile range], 231 [54-385] vs. 579 [213-1,379]×103/m3; p=0.056). However, the intervention group had a significant decrease in 0.3-㎛ particles (68 [-25 to 185] vs. 242 [72-588] ×103/m3; p=0.045). No adverse events occurred in either group. The device did not cause any inconvenience to the endoscopists or patients. Conclusions: This modified N95 respirator reduced the number of particles, especially 0.3-㎛ particles, generated during upper gastrointestinal endoscopy.

Isolation and Synthesis of Tryptamine Derivatives from a Symbiotic Bacterium Xenorhabdus nematophilus PC

  • Paik, Seung-Uk;Park, Myung-Kwang;Jhun, Seong-Hoon;Park, Heai-Ku;Lee, Chun-Soo;Cho, Bum-Rae;Byun, Hong-Sik;Choe, Seok-Burm;Suh, Seong-Il
    • Bulletin of the Korean Chemical Society
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    • v.24 no.5
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    • pp.623-626
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    • 2003
  • Nematophin and its analog incorporating tryptamine unit have been isolated and characterized from strain XRPC of a symbiotic bacterium Xenorhabdus nematophilus, which was newly isolated from Korean entomopathogenic nematodes. The stereoselective synthesis of these compounds was accomplished, and the relative configurations were determined. Nematophin exhibited potent antibacterial activities over several strains of methicillin-resistant S. aureus (MRSA) comparable to those of vancomycin.

Characterization of DRL1 and AtELPs gene

  • Cho, Kiu-Hyung;Choi, Hoon-Sung;Jun, Sang-Eun;Yi, Young-Byung;Hirokazu, Tsukaya;Kim, Gyung-Tae
    • Proceedings of the Korean Society of Plant Biotechnology Conference
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    • 2005.11a
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    • pp.196-196
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    • 2005
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