• Title/Summary/Keyword: University Portals

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Development of Model Plans in Three Dimensional Conformal Radiotherapy for Brain Tumors (뇌종양 환자의 3차원 입체조형 치료를 위한 뇌내 주요 부위의 모델치료계획의 개발)

  • Pyo Hongryull;Lee Sanghoon;Kim GwiEon;Keum Kichang;Chang Sekyung;Suh Chang-Ok
    • Radiation Oncology Journal
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    • v.20 no.1
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    • pp.1-16
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    • 2002
  • Purpose : Three dimensional conformal radiotherapy planning is being used widely for the treatment of patients with brain tumor. However, it takes much time to develop an optimal treatment plan, therefore, it is difficult to apply this technique to all patients. To increase the efficiency of this technique, we need to develop standard radiotherapy plant for each site of the brain. Therefore we developed several 3 dimensional conformal radiotherapy plans (3D plans) for tumors at each site of brain, compared them with each other, and with 2 dimensional radiotherapy plans. Finally model plans for each site of the brain were decide. Materials and Methods : Imaginary tumors, with sizes commonly observed in the clinic, were designed for each site of the brain and drawn on CT images. The planning target volumes (PTVs) were as follows; temporal $tumor-5.7\times8.2\times7.6\;cm$, suprasellar $tumor-3\times4\times4.1\;cm$, thalamic $tumor-3.1\times5.9\times3.7\;cm$, frontoparietal $tumor-5.5\times7\times5.5\;cm$, and occipitoparietal $tumor-5\times5.5\times5\;cm$. Plans using paralled opposed 2 portals and/or 3 portals including fronto-vertex and 2 lateral fields were developed manually as the conventional 2D plans, and 3D noncoplanar conformal plans were developed using beam's eye view and the automatic block drawing tool. Total tumor dose was 54 Gy for a suprasellar tumor, 59.4 Gy and 72 Gy for the other tumors. All dose plans (including 2D plans) were calculated using 3D plan software. Developed plans were compared with each other using dose-volume histograms (DVH), normal tissue complication probabilities (NTCP) and variable dose statistic values (minimum, maximum and mean dose, D5, V83, V85 and V95). Finally a best radiotherapy plan for each site of brain was selected. Results : 1) Temporal tumor; NTCPs and DVHs of the normal tissue of all 3D plans were superior to 2D plans and this trend was more definite when total dose was escalated to 72 Gy (NTCPs of normal brain 2D $plans:27\%,\;8\%\rightarrow\;3D\;plans:1\%,\;1\%$). Various dose statistic values did not show any consistent trend. A 3D plan using 3 noncoplanar portals was selected as a model radiotherapy plan. 2) Suprasellar tumor; NTCPs of all 3D plans and 2D plans did not show significant difference because the total dose of this tumor was only 54 Gy. DVHs of normal brain and brainstem were significantly different for different plans. D5, V85, V95 and mean values showed some consistent trend that was compatible with DVH. All 3D plans were superior to 2D plans even when 3 portals (fronto-vertex and 2 lateral fields) were used for 2D plans. A 3D plan using 7 portals was worse than plans using fewer portals. A 3D plan using 5 noncoplanar portals was selected as a model plan. 3) Thalamic tumor; NTCPs of all 3D plans were lower than the 2D plans when the total dose was elevated to 72 Gy. DVHs of normal tissues showed similar results. V83, V85, V95 showed some consistent differences between plans but not between 3D plans. 3D plans using 5 noncoplanar portals were selected as a model plan. 4) Parietal (fronto- and occipito-) tumors; all NTCPs of the normal brain in 3D plans were lower than in 2D plans. DVH also showed the same results. V83, V85, V95 showed consistent trends with NTCP and DVH. 3D plans using 5 portals for frontoparietal tumor and 6 portals for occipitoparietal tumor were selected as model plans. Conclusion : NTCP and DVH showed reasonable differences between plans and were through to be useful for comparing plans. All 3D plans were superior to 2D plans. Best 3D plans were selected for tumors in each site of brain using NTCP, DVH and finally by the planner's decision.

Personalized Information Delivery Methods for Knowledge Portals (지식포탈을 위한 개인화 지식 제공 방안)

  • Lee Hong Joo;Kim Jong Woo;Kim Gwang Rae;Ahn Hyung Jun;Kwon Chul Hyun;Park Sung Joo
    • Journal of Information Technology Applications and Management
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    • v.12 no.4
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    • pp.45-57
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    • 2005
  • In order to provide personalized knowledge recommendation services, most web portals for organizational knowledge management use category or keyword information that portal users explicitly express interests in. However, it is usually difficult to collect correct preference data for all users with this approach, and, moreover, users' preferences may easily change over time, which results In outdated user profiles and impaired recommendation qualify. In order to address this problem, this paper suggests knowledge recommendation methods for portals using user profiles that are automatically constructed from users' activities such as posting or uploading of articles and documents. The result of our experiment shows that the Proposed method can provide equivalent performance with the manual category or keyword selection method.

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A Study on the Incidence of Side Effects according to the Number of Beams in Intensity-modulated Radiation Therapy for Prostate Cancer using 15 MV (15 MV를 이용한 전립샘암 세기조절 방사선치료 시 빔의 개수에 따른 부작용 발생률에 관한 연구)

  • Joo-Ah Lee
    • Journal of the Korean Society of Radiology
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    • v.17 no.3
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    • pp.481-487
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    • 2023
  • In this study, we analyzed the incidence of side effects of photoneutron dose according to the number of beams during intensity-modulated radiotherapy of prostate cancer using 15 MV. The radiation treatment plan design for intensity-modulated radiation therapy for prostate cancer was established with a prescription dose of 220 cGy per dose and a total of 7260 cGy for 33 treatments. The linear accelerator used in the experiment is Varian's True Beam STx (Varian, USA). Photoneutron dose was generated by using 15 MV energy in the planning target volume (PTV). The treatment plan was designed with IMRT 5, 7, and 9 portals using the Eclipse System (Varian Ver 10.0, USA). An optically stimulated luminescence albedo neutron dosimeter (Landauer Inc., USA) was used to measure photoneutron dose. IMRT 5 portals, 1.7 per 1,000, 7 portals, 1.8 per 1,000, 9 portals, 2.0 per 1,000 were calculated as the probability of experiencing side effects on the thyroid gland due to photoneutron dose. This study studies the risk of secondary radiation exposure dose that can occur during intensity-modulated radiation therapy, and it is considered that it will be used as useful data in relation to stochastic effects in the future.

Neutron dosimetry depending on the number of portals for prostate cancer IMRT(Intensity-Modulated Radiation Therapy) (전립선암의 세기조절 방사선치료 시 조사문수별 중성자선량 평가)

  • Lee, Joo-Ah;Son, Soon-Yong;Min, Jung-Whan;Choi, Kwan-Woo;Na, Sa-Ra;Jeong, Hoi-Woun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.6
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    • pp.3734-3740
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    • 2014
  • The aim of this study was provide basic information and establish the criteria in radiation therapy planning by measuring the absorbed neutron dose of normal tissues and lesions according to the number of portals. From September 2013 to January 2014, 20 patients who were diagnosed with prostate cancer and were previously treated with radiation therapy were replanned retrospectively to measure the absorbed neutron dose distribution according to the number of portals. The absorbed neutron dose was measured in each of the 5, 7 and 9 portals using a 15 MV energy, which meant a therapeutic dose of 220 cGy. The optical stimulation luminescence dosimeter was separated by 20cm and 60cm away from the center of the field of view. As a result, the average radiation dose in the abdomen appeared to have a positive relationship with the number of portals, which was statistically significant (p<.05). The average radiation dose was $4.34{\pm}1.08$. The average radiation dose in the thyroid was $2.71{\pm}.37$. Although it showed a positive relationship with the number of portals, it did not have statistical significance. The number of portals and the neutron dose depending on the position showed a significant positive relationship, particularly in the abdomen. As a result of linear regression analysis, as the number of the portal increased in steps, the average volume of the neutrons increased significantly (0.416 times). In conclusion, efficient selection of the number of portals is needed considering the difference in the absorbed neutron dose in the normal tissues depending on the number of the portals.

The Analyses of Successful Strategy for Internet Portals: From the Analyses of M&A Cases (인터넷 포탈의 성공적인 분석: 인수합병 사례를 중심으로)

  • Chae, Soo-Wan;Kwon, Seung-Woo;Yoo, Byung-Joon
    • Information Systems Review
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    • v.9 no.2
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    • pp.85-108
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    • 2007
  • Currently, most of big IT companies attempt to penetrate into Internet portal industry aggressively in order to expand their channels(sale, distribution, marketing, R&D, and so on) and to acquire competitive advantages. Existing Internet portals also have become larger and more complex with continuous developments. Therefore, it is necessary to acquire competitive contents to survive the extreme competition and to satisfy diverse needs of customers. In this paper, we have done qualitative analyses on the cases of domestic and foreign major Internet portals which have acquired contents through of M&A and strategic alliances. In our analyses, we identify five factors crucial to the successes and failures of Internet portals. From the analyses, we find that the acquisition of UCC based contents and subscribers over the critical mass point are the two most important factors that should be simultaneously satisfied for the successful M&As. Additional analyses suggest how to acquire synergy effects from successful M&As.

Distribution and Evaluation of News on Portals: How News Use and Engagement Influence Portal News Credibility

  • Najin JUN
    • Journal of Distribution Science
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    • v.21 no.7
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    • pp.1-9
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    • 2023
  • Purpose: This study aims to understand if heterogeneous news is evenly consumed and distributed on portals as it examines people's news use and engagement behaviors and news credibility. Focusing on the four behaviors of news use, i.e., viewing news by keyword search, viewing news from subscribed sources, viewing news from the list of most-viewed news, and reading comments, and the three behaviors of news engagement, i.e., sharing news, 'liking' or 'recommending' news, and posting comments, this study investigates the relation between each of the behaviors and portal news credibility. Research design, data and methodology: From 2022 News Audience Survey in Korea, this study conducts a regression analysis to investigate the relations between each behavior and news credibility. Results: The results show a positive relation for the former two news use behaviors and the latter two news engagement behaviors, and a negative relation for the latter two news use behaviors. Conclusions: The positive relations between active news use and engagement behaviors and portal news credibility indicate that news consumers are more likely to use and engage in attitude-consistent news rather than attitude-challenging news, implying that heterogeneous news is less likely to be consumed and distributed evenly on portals across all news users.

Technical Note of Arthroscopic Subtalar Arthrodesis Using Posterior Portals - Operative Technique - (후방 삽입구를 이용한 관절경적 거골하 관절 유합술- 수술 방법-)

  • Lee, Keun-Bae;Choi, Jin;Park, Yu-Bok;Seo, Hyeong-Yeon;Suh, Jin-Soo
    • Journal of Korean Foot and Ankle Society
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    • v.9 no.2
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    • pp.193-196
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    • 2005
  • A posterior 3-portal arthroscopic approach with the patient in the prone position provides a novel and optimal approach for isolated subtalar arthrodesis. This approach facilitates access to the posterior talocalcaneal facet and facilitates safe access with regard to the posteromedial neuromuscular bundle. The technique involves prone positioning, establishment of two posterolateral portals and one posteromedial portal, arthroscopic posterior talocalcaneal facet debridement, percutaneous morcellized bone grafting and internal screw fixation. Preliminary results have shown high patient satisfaction, an excellent fusion rate and less postoperative morbidity than open subtalar arthrodesis.

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Evaluation of Photoneutron Dose for Prostate Cancer Radiation Therapy by Using Optically Stimulated Luminescence Dosimeter (OSLD) (전립선암 방사선치료 시 광자극발광선량계를 이용한 광중성자선량 평가)

  • Lee, Joo-Ah;Back, Geum-Mun;Kim, Yeon-Soo;Son, Soon-Yong;Choi, Kwan-Woo;Yoo, Beong-Gyu;Jeong, Hoi-Woun;Jung, Jae-Hong;Kim, Ki-Won;Min, Jung-Whan
    • Journal of radiological science and technology
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    • v.37 no.2
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    • pp.125-134
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    • 2014
  • This study is to provide basic information regarding photoneutron doses in terms of radiation treatment techniques and the number of portals in intensity-modulated radiation therapy (IMRT) by measuring the photoneutron doses. Subjects of experiment were 10 patients who were diagnosed with prostate cancer and have received radiation treatment for 5 months from September 2013 to January 2014 in the department of radiation oncology in S hospital located in Seoul. Thus, radiation treatment plans were created for 3-Dimensional Conformal Radiotherapy (3D-CRT), Volumetric-Modulated Arc Radiotherapy (VMAT), IMRT 5, 7, and 9 portals. The average difference of photoneutron dose was compared through descriptive statistics and variance analysis, and analyzed influence factors through correlation analysis and regression analysis. In summarized results, 3D-CRT showed the lowest average photoneutron dose, while IMRT caused the highest dose with statistically significance (p <.01). The photoneutron dose by number of portals of IMRT was $4.37{\pm}1.08mSv$ in average and statistically showed very significant difference among the number of portals (p <.01). Number of portals and photoneutron dose are shown that the correlation coefficient is 0.570, highly statistically significant positive correlation (p <.01). As a result of the linear regression analysis of number of portals and photoneutron dose, it showed that photoneutron dose significantly increased by 0.373 times in average as the number of portals increased by 1 stage. In conclusion, this study can be expected to be used as a quantitative basic data to select an appropriate IMRT plans regarding photoneutron dose in radiation treatment for prostate cancer.

A Study of Cancer Incidence Rate due to Photoneutron Dose during Radiation Therapy for Prostate Cancer Patients (전립샘암 환자의 방사선 치료 시 광중성자 선량으로 인한 암 발생률의 연구)

  • Lee, Joo-Ah
    • Journal of the Korean Society of Radiology
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    • v.16 no.4
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    • pp.471-476
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    • 2022
  • The purpose of this study was to study the probability of cancer occurrence due to photoneutron dose exposure of the colon and thyroid gland, which are normal organs, in 3D CRT, IMRT 5 portals, and IMRT 9 portals, which are radiotherapy methods for prostate cancer. The total prescribed dose for prostate cancer was 6600 cGy, 220 cGy per dose, and 30 divided irradiations were applied for the total number of times. After setting up the Rando phantom on the treatment table (couch) of the medical linear accelerator used in the experiment, an optically stimulated luminescence albedo neutron dosimeter was placed on the corresponding area of the large intestine and thyroid gland of the phantom for measurement. During 3D CRT of prostate cancer, the probability of secondary cancer due to photoneutron dose to the colon and thyroid gland, which are normal organs, was 1.8 per 10,000 people. And IMRT 5 portals were 8.7 per 10,000 people, which was about 5 times larger than 3D CRT. IMRT 9 portals derived the result that there is a probability that 1.2 people per 1,000 people will develop cancer. Based on this study, the risk of secondary radiation exposure due to the dose of photoneutrons generated during radiation therapy is studied, and it is thought that it will be used as useful data for radiation protection in relation to the stochastic effect of radiation in the future.