• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.25 no.1
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• pp.17-25
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• 1995

The purpose of this study was to obtain some informations for the radiographic differential diagnosis between odontogenic keratocyst and unicystic ameloblastoma in the mandible. The author compared and analysed the clinico-radiographic features of 48 cases of odontogenic keratocyst and 32 cases of unicystic ameloblastoma. The obtained results were as follows : 1. Odontogenic keratocyst and unicystic ameloblastoma occurred the most frequently in the 2nd and 3rd decades, and both lesions occurred with slight predilection in males. The most frequent lesional site was molar area in odontogenic keratocyst(50.0％) and mandibular angle and ramus area in unicystic amelobla-stoma(71.9％). 2. Cortical thinning and expansion were observed with similar occurrences in odontogenic keratocyst(77.l％) and in unicystic ameloblastoma(72.9％). 3. Typical undulating lesional border was observed more frequently in odontogenic keratocyst(79.2％) than in unicystic ameloblastoma(46.9％). 4. Well-defined lesional outline occurred more frequently in odontogenic keratocyst(97.9％) than in unicystic ameloblastoma(53.1％). 5. Root resorption of adjacent teeth occurred more frequently in unicystic ameloblastoma(65.2％) than in odontogenic keratocyst(18.8％) respectively, but loss of lamina dura was frequently observed in odontogenic keratocyst(79.2％). And tooth displacement occurred more frequently in odontogenic keratocyst(50.0％) than in unicystic ameloblastoma(17.4％). 6. Displacement of mandibular canal occurred more frequently in odontogenic keratocyst(75.0％) than in unicystic ameloblastoma(61.5％). 7. Inhomogeneous lesional radiolucency occurred more frequently in unicystic ameloblastoma(53.l％) than in odontogenic keratocyst(39.6％).

• Imaging Science in Dentistry
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• v.35 no.2
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• pp.77-82
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• 2005

Purpose : To reveal what is the distinct differential diagnostic differences between unicystic ameloblastoma and solid or multicystic ameloblastoma. Materials and Methods : 56 cases of ameloblastoma were retrospectively reviewed and evaluated among the patients who had taken CT scans at the department of Oral & Maxillofacial Radiology in Yonsei University Dental Hospital from January 1996 to December 2003. Results : In 56 cases, 21 cases $(37.5\%)$ were unicystic ameloblastoma, 35 cases $(62.5\%)$ were solid or multicystic ameloblastoma. Only 1 case $(4.8\%)$ of unicystic ameloblastoma and 4 cases $(11.4\%)$ of solid or multicystic ameloblastoma were occurred in maxilla. 13 cases $(61.9\%)$ of unicystic ameloblastoma were observed as unilocular, and 8 cases $(38.1\%)$ as lobulated. 5 cases $(14.3\%)$ of solid or multicystic ameloblastoma were observed as unilocular, 13 cases $(37.1\%)$ as lobulated, and 17 cases $(48.6\%)$ as multilocular. Tn the results from the measurements after correction of the buccolingual widths and heights to the mesiodistal lengths, there is a statistically significant difference between unicystic ameloblastoma and solid or multicystic ameloblastoma in ANCOVA test (p<0.05). Hounsfield units in the lesion were $24.9{\pm}8.8\;HU$ in unicystic ameloblastoma, $31.2{\pm}11.5\;HU$ in solid or multicystic ameloblastoma. There is no statistically significant difference (p>0.05). Conclusion : Characteristic differences between unicystic ameloblastoma and solid or multicystic ameloblastoma is that there is higher prevalence of solid or multicystic ameloblastoma that have lobulated or multilocular patterns. To measure the Hounsfield units in the lesion is helpful, but it is not a differential diagnostic point between unicystic ameloblastoma and solid or multicystic ameloblastoma.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.13 no.2
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• pp.160-166
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• 1991

In 1977, Robinson & Martinez described a distinct varient of ameloblastomas in which the response to curettage was found to be favorable, with a recurrence rate of 25%. They referred to this varient as unicystic ameloblastoma. Unicystic ameloblastoma occur most commonly in the second and third decades of life, which is considerablly younger than the average age of discovery for the classical ameloblastoma. For the accurate histopathological diagnosis of the unicystic ameloblastoma, the specimen obtained the excisional biopsy, complete enucleation or incisional biopsy from the multiple site of the lesion. The purpose of this report is to review of the literature and to present three cases in which an unicystic ameloblastoma appear to be arising in the wall of a dentigerous cyst.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.36 no.6
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• pp.553-555
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• 2010

Ameloblastoma is a common odontogenic tumor originating from the dental lamina, reduced dental epithelium and rests of Malassez, and represents 10% of all odontogenic tumors of the jaw. Unicystic ameloblastoma is normally encountered in young patients, and often occurs in the mandible, and is particularly associated with an impacted tooth. We encountered an unicystic ameloblastoma arising from a dentigerous cyst after the treatment of a radiolucent lesion on the mandible.

• Restorative Dentistry and Endodontics
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• v.26 no.2
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• pp.124-126
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• 2001

A case of an unicystic ameloblastoma of the mandible presenting as an apical periodontal cyst was reported. The lesion showed an unilocular radiolucency with well delineated border. Histologic examination revealed that a fibrous cyst wall with a lining that consists of partially of ameloblastic epithelium. The overlying epithelial cells are loosely cohesive and resemble stellate reticulum. The fibrous cyst wall of the cyst is infiltrated by typical follicular ameloblastoma. but devoid of inflammatory reaction in the cystic wall. Some considerations regarding differential diagnosis. pathogenesis and biologic behaviour of the lesion were discussed.

• Imaging Science in Dentistry
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• v.35 no.1
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• pp.47-50
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• 2005

Purpose : To acquire the useful diagnostic information through the analysis of the clinical and radiological characteristics of mandibular unicystic ameloblastoma. Materials and Methods : The researchers compared and analysed the clinical and radiological features of 79 cases of mandibular unicystic ameloblastoma confirmed by histopathlogic examination. Results : The results of our research showed that unicystic ameloblastomas occurred more frequently in males than in females and the incidence is the highest in the 2nd and 3rd decades. These lesions occurred most frequently in angle-ramus area, mandibular molar area, and anterior area in descending order respectively $68.4\%$, $24\%$, and $7.6\%$. These lesions had smooth ($54.4\%$) rather than undulating ($45.6\%$) borders. These lesions showed well- defined borders in $59.5\%$ among all the cases. Root resorption and loss of lamina dura were observed as $55.7\%$ and $58.5\%$ respectively. Displacement of mandibular canal was observed in $55.9\%$ among all the related cases. Internal pattern of lesional radiolucency was observed as even ($49.4\%$) or uneven ($50.6\%$). Conclusion : These results would be helpful in diagnosing of mandibular unicystic ameloblastoma. (Korean J Oral Maxillofac Radiol 2005; 35 : 47-50)

• Maxillofacial Plastic and Reconstructive Surgery
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• v.14 no.1_2
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• pp.160-168
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• 1992

Ameloblastoma is an aggressive but benign epithelial neoplasm of odontogenic origin, and the occurrence of odontogenic epithelium in the wall of a dentigerous cyst is well-known entity. The presence of ameloblastic proliferation in the walls of odontogenic cysts has been reported for many years. Cahn in 1933 described a case in which he considered an ameloblastoma to have originated in a dentigerous cyst, and numerous other cases of ameloblastomatous proliferation have since been reported. In 1977, Robinson and Martinez described a distinct variant of ameloblastoma in which the response to curettage was found to be favorable with a recurrence rate of 25%. The gross and microscopic features indicated that this variant vas associated with a large cystic cavity with either luminal or mural proliferation of ameloblastic tumor cells, and they referred to this variant as unicystic ameloblastoma. Unicystic ameloblastoma occurs most commonly in the second and third decades of life, which is considerably younger than the average age of discovery for the classical ameloblastoma. For the accurate histopathological diagnosis of the unicystic ameloblastoma, the specimen obtained the excisional biopsy, complete enucleation or incisional biopsy from the multiple site of the lesion. This article provides histopathologic evidence of multilocular unicystic ameloblastoma in which ameloblastic tissue was associated with a dentigerous cyst that was found in a 31-year-old female, and complete radiographic, photographic, and microscopic documentation is presented.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.33 no.5
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• pp.435-439
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• 2011

Ameloblastoma is an aggressive benign odontogenic epithelial tumour that may arise from the enamel organ, remnants of dental lamina, or the lining of an odontogenic cyst. It is usually categorized into solid or multicystic, unicystic, and peripheral types. Treatment ofameloblastomas include conservative methods such as marsupialisation, enucleation, and curettage; and radical treatments such as marginal or segmental resection. Radical treatments have resulted in lower recurrence rates; however, may also encounter esthetic, functional, and reconstructive problems. Unicystic ameloblastoma has been considered less aggressive and a lower recurrence tendency. Thus, many authors have recommended conservative treatment in cases of unicystic ameloblastoma. An 11 year-old boy presented with displaced second and third molars by luminal unicystic ameloblastoma in the mandible. Cyst enucleation, curettage, and third molar extraction were done. No signs of recurrence or esthetic problems such as facial asymmetry were seen radiologically and clinically, up to 8 years 2 months postoperatively.

• Imaging Science in Dentistry
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• v.41 no.1
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• pp.29-33
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• 2011

A 46-year-old man was referred to our hospital for treatment, complaining of swelling on the right mandibular molar region. Radiographic examination revealed a well defined multilocular radiolucent lesion with root resorption of right lower anteriors and molars. Following biopsy, a diagnosis of unicystic ameloblastoma of mural type was made and hemimandibulectomy was performed under general anesthesia. Histopathological examination of the surgical specimen exhibited a unicystic ameloblastoma of luminal, intraluminal, and mural type. Intraluminal proliferation was of plexiform pattern and mural proliferation showed unusual histopathological findings, which revealed follicular, acanthomatous areas coexisted with desmoplastic areas. This mural picture was similar to the so-called 'hybrid lesion of ameloblastoma', whose biological profile is not elicited due to the lack of adequate published reports. Two years follow up till date has not revealed any signs of recurrence.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.31 no.1
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• pp.70-73
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• 2005

An Ameloblastoma is one of the most common odontogenic tumors. The treatment of ameloblastoma has been controversial because of this disease entity as a slow-growing, locally invasive tumor with high rate of recurrence. Recurrence rate of ameloblastoma are reported 15% to 25% after radical treatment and 75% to 90% after conservative treatment. On the other hand, Robinson and Gardner reported that the recurrence rate after conservative treatment of unicystic ameloblastoma was lower than those of multicystic or solid lesion. In this report, what we want to show is to review the articles to find out pros and cons of conservative treatment of ameloblastoma. In addition we would like to discuss which requies conservative treatment or radical treatment are more acceptable through our case report.