• 동의생리병리학회지
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• 제20권5호
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• pp.1200-1210
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• 2006

This experiment was designed to investigate the effect of the CMT and MCMT hot water extract & ultra-fine powder on microglia and memory deficit model. The effects of the CMT and MCMT hot water extract on expression of IL-l${\beta}$, IL-6, TNF-${\alpha}$, NOS-II, COX-2, IL-10, TGF-${\beta}$1 mRNA and production of IL-lP, IL-6, TNF-a, NO, ROS in BV2 microglial cell line treated by lipopolysacchaide(LPS) ; serum glucose, uric acid, AChE activity of the memory deficit mice induced by scopolamine , behavior of the memory deficit mice induced by scopolamine and were investigated, respectively. The CMT and MCMT hot water extract suppressed the expression of IL-1${\beta}$, IL-6, TNF-${\alpha}$, NOS-II, COX-2 mRNA, production of IL-l${\beta}$, IL-6, TNF-${\alpha}$, NO, ROS and increased the expression of IL-10, TGF-${\beta}$l mRNA in BV2 microglial cell line treated by LPS. The MCMT hot water extract & ultra-fine powder increased glucose, decreased uric acid and AChE significantly in the serum of the memory deficit mice induced by scopolamine. The CMT and MCMT hotwater extract & ultra-fine powder groups showed significantly inhibitory effect on the scopolamine-induced impairment of memory in the experiment of Morris water maze. According to the above result, it is suggested that the CMT and MCMT hot water extract & ultra-fine powder might be usefully applied for prevention and treatment of dementia.

• 동의생리병리학회지
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• 제20권4호
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• pp.997-1008
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• 2006

This experiment was designed to investigate the effect of the CMT and PCMT hot water extract & ultra-fine powder on microglia and memory deficit model. The effects of the CMT and PCMT hot water extract on expression of $IL-l{\beta},\;IL-6,\;TNF-{\alpha}$, NOS-II, COX-2, IL-10, $TGF-{\beta}1$ mRNA and production of $IL-l{\beta},\;IL-6,\;TNF-{\alpha}$, NO, ROS in BV2 microglial cell line treated by lipopolysacchaide(LPS) , serum glucose, uric acid, AChE activity of the memory deficit mice induced by scopolamine , behavior of the memory deficit mice induced by scopolamine and were investigated, respectively. The CMT and PCMT hot water extract suppressed the expression of $IL-l{\beta},\;IL-6,\;TNF-{\alpha}$, NOS-11, COX-2 mRNA, production of $IL-l{\beta},\;IL-6,\;TNF-{\alpha}$, NO, ROS and increased the expression of IL-10, $TGF-{\beta}1$ mRNA in BV2 microglial cell line treated by LPS. The PCMT hot water extract & ultra-fine powder increased glucose, decreased uric acid and AChE significantly in the serum of the memory deficit mice induced by scopolamine. The CMT and PCMT hot water extract & ultra-fine powder groups showed significantly inhibitory effect on the scopolamine-induced impairment of memory in the experiment of Morris water maze. According to the above result, it is suggested that the CMT and PCMT hot water extract & ultra-fine powder might be usefully applied for prevention and treatment of dementia.

• 한국응용과학기술학회지
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• 제36권4호
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• pp.1281-1289
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• 2019

본 연구는 도로시설물의 염화칼슘 제거를 위한 미세기포 세척장비의 최적 운용조건에 대하여 성능평가를 수행하였다. 실험에 사용된 미세기포의 직경은 196.6±100.6nm에 1.36×108개/ml의 농도를 나타낸다. 세척장비의 분사장치에 대한 실험 성능결과, 100bar의 분사압력에서 100cm, 150cm 분사거리에 약 93%, 91%의 세척효율이 나타나는 것으로 확인되었다. 미세기포 생성(순환)횟수를 2-6회로 증가시킴에 따라 최소 1%에서 7%까지 염화물 제거율이 높아짐을 확인하였다. 미세기포 생성 공기유량을 4 ml/min에서 0.5 ml/min으로 낮춤에 따라 세척효율이 최대 30%까지 증가하는 것이 확인되었다. 일반 상수도와 미세기포의 세척효율은 미세기포가 일반상수도 보다 세척효율이 25% 높게 나타났다.

• 대한한의학회지
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• 제28권2호통권70호
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• pp.137-154
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• 2007

Objective : This experiment was designed to investigate the effect of the GYZB hot water extract & ultra-fine powder on the Alzheimer's disease model induced by amyloid ${\beta}$ protein (${\beta}A$). Method : We measured the effects of the GYZB hot water extract on expression of $IL-1{\beta}$, IL-6 mRNA and production of IL-6, $TNF-{\alpha}$ in the BV2 microglial cell line treated with lipopolysaccharide (LPS). The effects of the GYZB hot water extract & ultra-fine powder on (1) the behavior, (2) expression of $IL-1{\beta}$ and $TNF-{\alpha}$, (3) glucose in serum, (4) the infarction area of the hippocampus, and brain tissue injury in mice induced with Alzheimer's diseased by ${\beta}A$ were investigated. Results : The GYZB hot water extract suppressed the expression of $IL-1{\beta}$ and IL-6 mRNA and significantly suppressed the production of IL-6 and $TNF-{\alpha}$ in the BV2 microglial cell line treated with LPS. The GYZB hot water extract & ultra-fine powder showed a significant inhibitory effect on the memory deficit of the mice with Alzheimer's disease induced by ${\beta}A$ in the Morris water maze experiment, which measured stop-through latency and distance movement-through latency. The GYZB ultra-fine powder significantly suppressed the expression of $IL-1{\beta}$ and $TNF-{\alpha}$ protein, and the GYZB hot water extract significantly suppressed the expression of $TNF-{\alpha}$ protein in the microglial cell of mice with Alzheimer's disease induced by ${\beta}A$. The GYZB hot water extract & ultra-fine powder reduced the infarction area of hippocampus in the mice with Alzheimer's disease induced by ${\beta}A$. Conclusions : These results suggest that GYZB hot water extract & ultra-fine powder may be effective for the prevention and treatment of Alzheimer's disease. Investigation into the clinical use of GYZB for Alzheimer's disease is suggested for future research.

• 한국분말재료학회지
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• 제20권2호
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• pp.100-106
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• 2013

Ultra-fine zirconium carbide (ZrC) powder with nano-sized primary particles was synthesized by the carbothermal reduction method by using nano-sized $ZrO_2$ and nano-sized graphite powders mixture. The synthesized ZrC powder was well dispersed after simple milling process. After heat-treatment at $1500^{\circ}C$ for 2 h under vacuum, ultra-fine ZrC powder agglomerates (average size, $4.2{\mu}m$) were facilely obtained with rounded particle shape and particle size of ~200 nm. Ultra-fine ZrC powder with an average particle size of 316 nm was obtained after ball milling process in a planetary mill for 30 minutes from the agglomerated ZrC powder.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2001년도 춘계학술대회 논문집
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• pp.147-150
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• 2001

The ARB (Accumulative Rolling Bonding) Process was applied to a 6061 Al alloy to obtain ultra-fine grains. After 4 ARB cycles at $315^{\circ}C$, original equilibrium large grains were transformed to ultra-fine grains of several hundred nano-meter size with nonequilibrium grain boundaries. At lower number of cycles, microsutcture of highly-tangled dislocation cells were observed. Large grains and coarsened precipitates filled the microstructure of specimens experienced ARB cycles more than 5. Sliding wear tests using a pin-on-disk type wear tester were conducted on the ARB processed 6061 Al alloy plate. Wear rates of the 6061 Al alloy increased with the increase of ARB cycle number as well as the applied load. Worn surfaces and debris, cross-sections of the worn specimen were examined with scanning electron microscopy (SEM) to investigate the wear mechanism of the ultra-fine grained 6061 Al Tensile properties of the 6061 Al alloy were also studied and used to correlate the wear test results with the microstructures, which evolved continuously with the number of ARB cycles.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2016년도 춘계 학술논문 발표대회
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• pp.45-46
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• 2016

As the demand for super tall buildings is currently increased in domestic and foreign countries, some kinds of ultra-high strength concretes are being developed actively. Since the cross section of concrete becomes smaller thanks to such kinds of ultra-high strength concretes, the concrete structures can be much bigger, more gigantic and much ultra-high. And as another benefit which is generated thanks to the enhancement of the durability performance, the maintenance expenses are also saved. However, since low W/B ultra-high concrete has a high possibility that many cracks can occur in the initial period due to the self-shrinkage caused by the self-desiccation as one of the blending characteristics, the problem becomes bigger by influencing the safety of a structure. Therefore, in this study, it is intended to analyze the effects of substituting some limestone-based ultra-high strength mortar with electric arc furnace oxidizing slag fine aggregates on the self-shrinkage of mortar.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2015년도 춘계 학술논문 발표대회
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• pp.71-72
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• 2015

As this study is the one related to the ultra high strength concrete essentially used for high rise buildings, it has analyzed on the flowability of ultra high strength concrete according to the variation of coarse aggregate and fine aggregate. The coarse aggregate was planned as two types including Granite Aggregate (GA) and crushed coarse Limestone Aggregate (LA) while fine aggregate was planned as four types including Sea Sand (SS), Limestone Crushed Fine Aggregates (LFA), Electric Arc Furnace Oxidizing Slag Aggregates (EFA) and Crushed Sand (CS) to perform experiment with a total of eight variables. As a result of analyzing slump flow, 500mm concentration time, U-Box and L-Flow, etc. among the characteristics of fresh concrete, a mix using LA+LFA is determined to show high flowability in case of applying ultra high strength concrete.

• 한국대기환경학회지
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• 제22권3호
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• pp.353-360
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• 2006

This study identified a particle size distribution (PSD) of fine particulate matter and emission characteristics of V and Ni by the comparison between anthropogenic sources of oil combustion (industrial boiler, oil power plant, etc.) and lab-scale combustion using a drop-tube furnace. In oil combustion source, the mass fraction of fine particles (less than 2.5 micrometers in diameter) was higher than that of coarse particles (larger than 2.5 micrometers in diameter) in $PM_{10}$ (less than 10 micrometers in diameter) as like in lab-scale oil combustion. In addition to this, it was identified that ultra-fine particles (less than 0.1 micrometers in diameter) had a large distribution in fine particles. Toxic metals like V and Ni had large mass fractions in fine particles, and most of all was distributed in ultra-fine particles. Most of ultra-fine particles containing toxic metals have been emitted into ambient by combustion source because it is hard to control by the existing air pollution control device. Hence, we must be careful on these pollutants because it is obvious that these are associated with adverse health and environmental effect.

• 전기전자학회논문지
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• 제6권1호
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• pp.21-29
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• 2002

본 논문에서는 전부 디지털 회로로 구성된 고 해상도의 DLL(Delay Locked Loop)를 제안하였다. 제안된 회로는 위상 검출기, 지연 선택 블록, 그리고 각각의 지연 체인을 가지는 Coarse, Fine 그리고 Ultra Fine 위상조정 블록의 삼 단의 형식으로 되어 있다. 첫 번째 단은 Ultra Fine 위상조정블록으로 고 해상도를 얻기 위하여 Vernier Delay Line을 사용하였다. 두 번째와 세 번째 단은 Coarse와 Fine 위상조정블록으로 각각의 단위 지연 체인을 이루는 단위 지연 소자의 해상도 만큼의 위상 제어를 하게 되며, 두 단은 상당히 비슷한 구조를 이루고 있다. 회로는 HSPICE를 이용하여 공급 전압이 3.3V인 $0.35{\mu}m$ CMOS 공정으로 시뮬레이션 되었다. 시뮬레이션 결과 회로의 해상도를 약 10ps로 높일 수 있었으며, 동작 범위는 250MHz에서 800MHz 이다.