• Title/Summary/Keyword: Ulmus

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Cytotoxicity of Folkloric Medicine in Murine and Human Cancer Cells (천연물로부터 항암물질의 분리)

  • Lee, Ihn-Rhan;Song, Ji-Young;Lee, Yun-Sl
    • Korean Journal of Pharmacognosy
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    • v.23 no.3
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    • pp.132-136
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    • 1992
  • The whole plants of Selaginella tamariscina, Orostachycis japonicus, the cortex of Ulmus mandshurica, and the wood of Alnus japonica have been used as folk medicine for treating cancer. The cytotoxic activity of these plants were tested using a calorimetric tetrazolium assay (MTT assay). S. tamariscina and A. japonica showed mild $IC_{50}$ value, comparing with O. japonicus and U. mandshurica. So, MeOH extracts of S. tamariscina and A. japonica were partitioned into $CHCl_3$, EtOAc and n-BuOH, successively. The $CHCl_3$, EtOAc and BuOH fractions of S. tamariscina and A. japonica showed low percent of survival against $P_{388}$ and $MKN_{45}$ cells respectively. To isolate active components, they were subjected to silica gel column chromatography. Compound I was obtained from EtOAc extracts of S. tamariscina and identified as amentoflavone by chemical and spectral analysis. Amentoflavone inhibited the survival of P388 cells dose dependently, while not clearly inhibited that of $MKN_{45}$ cells.

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Vegetation Structure and Ecological Properties of Eleutherococcus senticosus Population (가시오갈피(Eleutherococcus senticosus)개체군의 식생구조와 생태특성)

  • Jung, Jiyoung;Gwon, Jaehwan;Song, Hokyung
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.16 no.5
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    • pp.27-38
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    • 2013
  • This study was conducted to analyze the correlation between vegetation, environmental factors, and soil characteristic of an endangered species, Eleutherococcus senticosus. Eighteen quadrats in population zones of Seoraksan, Odaesan, Chiaksna, Duckhangsan, Sobaeksan, Juwangsan, and, Jirisan were set up and ordination was analyzed. In the study sites, soil pH, available phosphorous, organic matter and nitrogen were ranged from 5.06~5.43, 24.63~57.77mg/kg, 14.01~18.37%, and 0.63~0.75%, respectively. Eleutherococcus senticosus is classified into Morus bombycis dominant population, Cornus controversa dominant population, and Eleutherococcus senticosus typical population. The importance value of Acer pictum subsp. mono, Morus bombycis, Magnolia sieboldii, Cornus controversa, Tilia taquetii, and Ulmus laciniata in Eleutherococcus senticosus population were 23.76%, 23.61%, 18.06%, 17.82, 15.31%, and 13.57%, respectively. The correlation between vegetation and environmental factors of Eleutherococcus senticosus vegetation distribution were shown to be affected by altitude, slope, and direction.

Study on the Vegetation and Flora of Nonsan Economical Forest Growing Site (논산 경제림 육성단지의 식물상 및 식생 연구)

  • Oh, Hyun-Kyung;Choi, Yeon-Ho;Beon, Mu-Sup
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.11 no.4
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    • pp.37-45
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    • 2008
  • The vascular plants of the studied area in Nonsan economical forest growing site appeared to be 341 taxa; 81 families, 218 genera, 290 species, 1 subspecies, 42 varieties and 9 forms. Based on the list of Korean endemic plants, 5 taxa existed; Cephalotaxus koreana, Thalictrum actaefolium, Asperula lasiantha, Populus tomentiglandulosa (Planted species), Paulownia coreana (Planted species). Specific plant species by floral region were total 13 taxa; Cirsium setidens in class III, Potentilla dickinsii in class II, Cephalotaxus koreana, Pinus koraiensis (Planted species), Hosta capitata, Juglans mandshurica, Alnus hirsuta, Quercus variabilis, Ulmus parvifolia, Dictamnus dasycarpus, Gwenia biloba var. parviflora, Vaccinium oldhami, Trigonotis icumae in class I. The naturalized plants in this site were 9 families, 19 genera, 20 species, 1 varieties, 21 taxa and naturalization rate was 6.1% of all 341 taxa vascular plants. The communities were classified into Quercus acutissima community, Pinus densiflora community, Quercus variabilis community, Platycarya strobilacea community, Quercus aliena community of natural forests and Pinus rigida community, Metasequoia glyptostroboides community, Larix leptolepis community of artificial forests.

Environments of Post-Glacial Age at Sorori, Reconstructed by the Species of Excavated Woods (청원 소로리 후빙기 시대의 환경 -출토목재의 수종분석을 중심으로-)

  • 박원규;김수철;이융조
    • The Korean Journal of Quaternary Research
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    • v.17 no.1
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    • pp.1-6
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    • 2003
  • One hundred fifty six pieces of woods were excavated at the muddy sand layer (post-glacial age: about 8,800 bp) above the upper peat layer from Sarori, Chungwongun, Korea in the central Korea. Due to the deteriorated structure of peat woods, all samples were embedded in PEG(polyethylene glycol) 2000 and then sectioned using a rotary microtome. Only two species were found; Alnus spp.(95%) and Ulmus spp.(5%). No conifers were found. Species composition indicates that the climate condition of central Korean peninsula around 8,800 bp was little wetter condition. The sampled region at the Sarori appeared to be a swamp or riverside.

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Vegetation Sectional View and Flora in the Sinpyeong Stream (Imsil), Churyeong Stream (Jeongeup) (신평천(임실), 추령천(정읍) 일대의 식물상 및 식생 단면도)

  • Oh, Hyun-Kyung;Beon, Mu-Sup
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.14 no.2
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    • pp.59-81
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    • 2011
  • The flora of the Sinpyeong and Churyeong stream were listed 324 taxa; 87 families, 227 genera, 289 species, 1 subspecies, 31 varieties and 3 forms. The Sinpyeong stream were 249 taxa and Churyeong stream were 221 taxa. Based on the rare plants (IUCN) by the Korea Forest Service and Korea National Arboretum were recorded; Penthorum chinense (Crassulaceae), etc. and endemic plants, 6 taxa; Weigela subsessilis (Caprifoliaceae), Lycoris flavescens (Amarylidaceae), etc. Based on the specific plants by floral region were total 12 taxa (3.7% of all 324 taxa of flora); Monochoria korsakowi (Pontederiaceae), etc. in class III. 10 taxa (Salix glandulosa (Salicaceae), Ulmus parvifolia (Ulmaceae), Impatiens noli-tangere (Balsaminaceae), Grewia biloba var. parviflora (Tiliaceae), Nymphoides peltata (Gentianaceae), Actinostemma lobatum (Cucurbitaceae), Cirsium pendulum (Compositae), Microstegium japonicum (Gramineae), etc.) in class I. Based on the naturalized plants, 51 taxa and ecosystem disturbing wild plants, 6 taxa (Rumex acetosella, Sicyos angulatus, Aster pilosus, Ambrosia artemisiaefolia, Hypochaeris radicata, Paspalum distichum var. distichum) and naturalization rate was 15.7% of all 324 taxa of flora, urbanization index was 18.8% of all 271 taxa of naturalized plants. Based on the hydrophytes, 23 taxa and emergent hydrophytes were 17 taxa, floating-leaved hydrophytes were 3 taxa, submergent hydrophytes were 2 taxa, free-floating hydrophytes was Spirodela polyrhiza.

Growth-inhibiting Effects of Brazilian and Oriental Medicinal Plants on Human Intestinal Bacteria

  • Kim, Moo-Key;Lee, Sung-Eun;Lee, Hoi-Seon
    • Journal of Applied Biological Chemistry
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    • v.43 no.1
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    • pp.54-58
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    • 2000
  • Methanol extracts of 27 Brazilian plant samples and 10 oriental medicinal plant samples (27 families), using spectrophotometric and paper disc agar diffusion methods under anaerobic conditions, were tested in vitro for their growth-inhibiting activities against Bifidobacterium longum, Bifidobacterium bifidum, Bifidobacterium adolescentis, Clostridium perfringens, and Bacteroides fragilis. The responses varied with bacterial strains, plant species, and tissues sampled. In a test with B. longum and B. bifidum(20 mg/disc), extracts of Acanthopanax sessilifolinus stem bark and Ampelozizyphus amazonicus leaves strongly inhibited the growth of B. longum, whereas other plant samples did not inhibit any intestinal bacteria tested. At 5 mg/disc, adding extracts of Aralia eleta, Euterpe oleracea, and Syzygium guineense to the media strongly inhibited the growth of C. perfringens and B. fragilis without growth inhibition of B. adolescentis, B. longum, and B. bifidum. Extracts of Jacaranda mimosifolia and Ulmus paraifolia significantly inhibited the growth of C. perfringens and B. fragilis as well as B. adolescentis. These results may be indications of at least one of the pharmacological actions of the five Brazilian plants but not oriental medicinal plants tested.

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A Case of Acute Liver Injury Caused by Comfrey and so on with Oriental Medicine (Comfrey 등으로 발생한 독성 간손상 환자의 한방치료 1례)

  • Park, Bong-Ky;Jung, Tae-Young;Cho, Jung-Hyo;Son, Chang-Gue
    • The Journal of Internal Korean Medicine
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    • v.30 no.1
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    • pp.249-255
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    • 2009
  • Currently, drug-induced liver injury (DILl) has been reported to be common cause of acute hepatitis, and oriental medicine and folk remedies are no exception. However, because many studies about DILl have been reported by western medical society. they has taken the initiative of DILl not only for western drugs but also herbs. So, academia of oriental medicine should make an effort to progress herb-related DILl studies. We describe a patient of acute liver injury which had been caused by comfrey, albizzia julibrissin, ulmus davidiana var. japonica, red ginseng. We hope that this report helps for studying the diagnosis and management of herb-derived DILl. and for establishing a standard of oriental therapy to DILL.

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Screening for Antioxidant Activity of Plants and Marine Algae and Its Active Principles from Prunus davidiana

  • Choi, Jae-Sue;Lee, Ji-Hyeon;Park, Hae-Jin;Kim, Hyung-Geun;Young, Han-Suk;Mun, Sook-Im
    • Korean Journal of Pharmacognosy
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    • v.24 no.4
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    • pp.299-303
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    • 1993
  • The antioxidant activity of methanol extracts of plants and marine algae was tested by using 1,1-diphenyl-2-picrylhydrazyl(DPPH). Five plant extracts(Prunus davidiana, Eriobotrya japonica, Artemisia iwayomogi, Stirodella tolyrrhiza and Ulmus davidiana) and two algae (Ecklonia stolonifera and Symphycoladia latiuscula) were found to be the most effective in DPPH radical scavenging activity. The methanol extract obtained from the stems of Prunus davidiana was fractionated with several solvents. The ethylacetate soluble fraction exhibiting the strongest antioxidant activity was further purified by repeated silica gel and Sephadex LH-20 column chromatography. Antioxidant flavonoids and flavonoid glycosides were isolated and the most active ones was identified as (+)-catechin by MS, $^1H-NMR$ and $^{13}C-NMR$. Its antioxidant activity was higher than that oil vitamin C.

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Growing Environment Characteristics and Vegetation Structure of Daphne Pseudomezereum var. Koreana Native Habitats in Korea

  • Lee, Da-Hyun;Son, Ho-Jun;Park, Sung-Hyuk;Kim, Se-Chang;Park, Wan-Geun
    • Journal of Forest and Environmental Science
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    • v.35 no.1
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    • pp.31-40
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    • 2019
  • Daphne pseudomezereum var. koreana is an endangered deciduous shrub distributed in mountain areas that is vulnerable to climate change. The purpose of this study was to provide foundational data on the physical characteristics, soil environment, and vegetation structure of habitats of Daphne pseudomezereum var. koreana habitat in Korea in order to help with management decisions on ecosystem restoration. Rock exposure was 15 to 35%, with an average of 24%. The native habitat of D. pseudomezereum included 129 taxa consisting of 46 families and 95 genera. Two-way cluster analysis divided the habitat into three plant communities: Community I (dominaterd by Tilia amurensis and Quercus mongolica), Community II (dominaterd by Fraxinus rhynchophylla and Acer pseudosieboldianum), and Community III (dominaterd by Ulmus davidiana var. japonica). The diversity indices for Communities I, II, and III were 1.124, 1.047 and 0.932, respectively. The soils were loam or clay loam. Soil pH, organic matter content, and available phosphoric acid were 5.40, 14.38%, and 31.08 ppm, respectively. Ordination analysis resulted that most significant factors influencing D. pseudomezereum distribution were magnesium content of soil, shrub layer, and altitude.

Anti-Allergic Effect of Fermented Extracts of Medicinal Plants Andrographis paniculate, Salvia plebeia R. Br., Canavalia gladiate, Eleuthorococcus senticosus, Ulmus davidiana var. japonica, and Clerodendrum trichotomum Thunb. ex Murray

  • Mi Jeong, Choi;Yu Ri, Kim
    • Microbiology and Biotechnology Letters
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    • v.50 no.4
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    • pp.512-521
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    • 2022
  • Since the main symptoms of COVID-19 involve the respiratory system, the infection rate of this disease is predicted to be higher in patients with other respiratory conditions such as allergic rhinitis. In such a situation, it will be meaningful to conduct research on an allergy treatment that has fewer side effects and can effectively reduce allergy symptoms. Here, we prepared experimental samples under various fermentation conditions with mixed extracts of six medicinal plants. To examine the anti-allergic efficacy of these samples, an egg albumin-induced allergic rhinitis animal model experiment, a serum histamine and IgE experiment, and a COX and LO inhibitory activity experiment were conducted. As a result of animal experiments, OVA+SP-4 showed superior efficacy compared to OVA+SP-1 in nasal rubbing and sneezing experiments and had anti-allergic efficacy similar to that of OVA-cetirizine. The serum histamine concentration of OVA+SP-4 was also 1.3 times higher than that of the OVA+cetirizine group, showing a high histamine reduction ability, and IgE showed the same trend. An analysis of COX inhibitory efficacy also confirmed that COX-1 and COX-2 inhibitory efficacy is high, and the longer the fermentation time, the higher the antiallergic efficacy. The composition proposed by this study is expected to have a significant effect on sustainable allergy prevention and treatment in the future by applying it to human patients.