• Bulletin of the Korean Chemical Society
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• 제33권4호
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• pp.1285-1289
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• 2012

RAP80 plays a key role in DNA damage responses by recognizing K63-linked polyubiquitin moieties through its two ubiquitin-interacting motif (UIM) domains. The linker between the two UIMs possesses a phosphorylation site, but the relationship between phosphorylation and polyubiquitin recognition remains elusive. We investigated the interaction between a phosphorylation-mimic RAP80 mutant S101E and linear polyubiquitins, structurally equivalent to the K63-linked ones, using isothermal titration calorimetry (ITC). ITC analysis revealed differential binding affinities for linear tetraubiquitin by otherwise equivalent UIMs in S101E. Mutational analysis supported such differential polyubiquitin recognition by S101E. Our results suggest a potential crosstalk between polyubiquitin recognition and phosphorylation in RAP80.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1996년도 한국자동제어학술회의논문집(국내학술편); 포항공과대학교, 포항; 24-26 Oct. 1996
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• pp.1336-1339
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• 1996

In this paper, we design implement an Object-Oriented Graphic System Configuration Editor for Access Control Systems. 'Visual Builder', with such functions as graphic drawing, system configuration, graphic management, processing of user input through graphics. Visual Builder is designed to be well separated from and independent of S/W parts closely coupled with the underlying H/W and thus to improve its reusability and maintainability.

• 한국정보처리학회논문지
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• 제2권3호
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• pp.324-334
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• 1995

대부분의 사용자 인터페이스 관리 시스템은 사용자 인터페이스의 대화 모델을 채 택하고 있다. 사용자 인터페이스 관리 시스템의 구현은 채택된 사용자 인터페이스의 대화 모델에 의해 강한 영향을 받는다. 모델-뷰-콘트롤러(Model-View-Controller : MVC) 프레임웨이 Smalltalk 환경에서 사용자 인터페이스 개발의 여러 측면에서 기여한 동안 사용자 인터페이스는 강하게 결합된 모델, 뷰, 콘트롤러 클래스를 가진 MVC를 이 용하여 생성되었다. 이러한 결합은 소프트웨어 부품의 재사용을 방해하였다. 따라서 본 논문에서는 MVC모델이 갖는 강한 결합력으로 인한 소프트웨어 재사용의 저하를 해 결하기 위해, 상호 작용의 구문적 관리를 하는 다이알로그 객체를 추가하여 사용자로 부터 생성된 메세지가 콘트롤러에 의해 바로 값이 변경되지 않고 다이알로그에 전달 되도록 MVCD모델을 제안하였다. 메세지를 전달받은 다이알로그 객체는 모델 객체의 값 을 변경하기 위해 모델 객체를 호출한다. 모델 객체는 active 값들을 가지고 있기 때 문에 값의 변경은 연결된 콘크롤러 객체에게 전달된다. 최종적으로 콘트롤러 객체는 새로운 값을 변경하고 뷰 객체를 수정한다. 이러한 사용자 대화 모델에 기반을 둔 사 용자 인터페이스 구축기를 X-윈도우상에서 OSF/Motif을 이용하여 개발하였다.

• 산업공학
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• 제12권2호
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• pp.294-304
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• 1999

This paper describes the theoretical background and detailed structure of Navi-HEGS (Navigation system Human factors Evaluation and Guideline System) which has been developed for the human factors and HMI(Human-Machine Interface) researches for a CNS (Car Navigation System) and a digital map. Navi-HEGS is and integrated system that consists of a digital map UIMS(User Interface Management System), a CNS simulator, various evaluation tools, and a design guideline system. If Navi-HEGS is properly applied and utilized, it is possible to extract the substantial users requirements and preferences of a CNS and a digital map and then, these requirements can be simulated and evaluated with various human factors evaluation techniques. Applications of Navi-HEGS can improve the CNS usability, drivers safety and performance that directly affect the success of ITS(Intelligent Transport System). Also, results can be used as the basic data to establish the standards and design guidelines for the driver-centered CNS design.

• 산업경영시스템학회지
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• 제23권60호
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• pp.47-55
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• 2000

Two experiments were conducted to examine the relationships between the color structure and the user preference of a CNS (Car Navigation System) digital map in terms of HSE (Human Sensibility Ergonomics). In the first experiment, the user's preference of color structures were investigated from the subjects' self-designed digital maps using a CNS digital map UIMS (User Interface Management System): in the second, statistical relation models between the user's color structure satisfaction level and the color components of CIE (Commission Internationale de ι'Eclairage) of the real products were suggested. For each experiment, CIE L*u*v* and CIE LCH color space were adapted, respectively, because they have their own characteristics of perceptual uniformity which enables the color components to transform a linear function.

• The Journal of Asian Finance, Economics and Business
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• 제8권5호
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• pp.117-126
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• 2021

Microfinance focuses on economic development at a minute level. Microfinance is adopted to reduce the poverty level in the economic system. This study is conducted to investigate the microfinance institutions' outreach, its growth, and challenges faced by the Microfinance Banks (MFBs) and Microfinance Institutions (MFIs). Data is collected from MFBs and MFIs working in Muzaffarabad as well as from interviews and focus group discussions. Findings are based upon lending, headcount ratio, offers, the value of their offer, and the possible growth chances of microfinance in Muzaffarabad. In addition to this, the challenges associated with microfinance outreach have been highlighted during analysis and guidelines have been provided to the MFBs and MFIs to increase their outreach. The sector is financially unstable which is attributable to its reliance on conventional sources of funding. The industry faces several endogenous as well as exogenous challenges from its environment which obstructs its growth. Further, it helps the policymakers to work on the development of the region and provide the base for further future research work.