• Bulletin of the Korean Chemical Society
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• v.33 no.4
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• pp.1285-1289
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• 2012

RAP80 plays a key role in DNA damage responses by recognizing K63-linked polyubiquitin moieties through its two ubiquitin-interacting motif (UIM) domains. The linker between the two UIMs possesses a phosphorylation site, but the relationship between phosphorylation and polyubiquitin recognition remains elusive. We investigated the interaction between a phosphorylation-mimic RAP80 mutant S101E and linear polyubiquitins, structurally equivalent to the K63-linked ones, using isothermal titration calorimetry (ITC). ITC analysis revealed differential binding affinities for linear tetraubiquitin by otherwise equivalent UIMs in S101E. Mutational analysis supported such differential polyubiquitin recognition by S101E. Our results suggest a potential crosstalk between polyubiquitin recognition and phosphorylation in RAP80.

• 제어로봇시스템학회:학술대회논문집
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• 1996.10b
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• pp.1336-1339
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• 1996

In this paper, we design implement an Object-Oriented Graphic System Configuration Editor for Access Control Systems. 'Visual Builder', with such functions as graphic drawing, system configuration, graphic management, processing of user input through graphics. Visual Builder is designed to be well separated from and independent of S/W parts closely coupled with the underlying H/W and thus to improve its reusability and maintainability.

• The Transactions of the Korea Information Processing Society
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• v.2 no.3
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• pp.324-334
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• 1995

Most UIMS(User Interface Management System) adopt dialogue model of user interface Implementation of UIMS influenced by adopted dialogue model of user interface strongly. While the Model-View-Controller framework has contributed to many aspects of user interface development in Smalltalk environment- user interfaces generated with MVC have highly coupled model, view, and controller classes. Such coupling impedes the reuse of software component. So In this paper, we suggest MVCD model to resolve a decline of reuse with MVC have highly coupled. User messages are not changed by Controller immediately, but sent to Dialogue object which maintains the syntatic structure of the interaction. Dialogue object invokes Model object to updates is value. Since Model objects have active values, the value change propagates to the linked Controllers. Finally, Controller object convert the new value and update the View object. User interface builder is implemented on X-window with OSF/Motif that is base on this user dialogue model.

• IE interfaces
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• v.12 no.2
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• pp.294-304
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• 1999

This paper describes the theoretical background and detailed structure of Navi-HEGS (Navigation system Human factors Evaluation and Guideline System) which has been developed for the human factors and HMI(Human-Machine Interface) researches for a CNS (Car Navigation System) and a digital map. Navi-HEGS is and integrated system that consists of a digital map UIMS(User Interface Management System), a CNS simulator, various evaluation tools, and a design guideline system. If Navi-HEGS is properly applied and utilized, it is possible to extract the substantial users requirements and preferences of a CNS and a digital map and then, these requirements can be simulated and evaluated with various human factors evaluation techniques. Applications of Navi-HEGS can improve the CNS usability, drivers safety and performance that directly affect the success of ITS(Intelligent Transport System). Also, results can be used as the basic data to establish the standards and design guidelines for the driver-centered CNS design.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.23 no.60
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• pp.47-55
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• 2000

Two experiments were conducted to examine the relationships between the color structure and the user preference of a CNS (Car Navigation System) digital map in terms of HSE (Human Sensibility Ergonomics). In the first experiment, the user's preference of color structures were investigated from the subjects' self-designed digital maps using a CNS digital map UIMS (User Interface Management System): in the second, statistical relation models between the user's color structure satisfaction level and the color components of CIE (Commission Internationale de ι'Eclairage) of the real products were suggested. For each experiment, CIE L*u*v* and CIE LCH color space were adapted, respectively, because they have their own characteristics of perceptual uniformity which enables the color components to transform a linear function.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.5
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• pp.117-126
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• 2021

Microfinance focuses on economic development at a minute level. Microfinance is adopted to reduce the poverty level in the economic system. This study is conducted to investigate the microfinance institutions' outreach, its growth, and challenges faced by the Microfinance Banks (MFBs) and Microfinance Institutions (MFIs). Data is collected from MFBs and MFIs working in Muzaffarabad as well as from interviews and focus group discussions. Findings are based upon lending, headcount ratio, offers, the value of their offer, and the possible growth chances of microfinance in Muzaffarabad. In addition to this, the challenges associated with microfinance outreach have been highlighted during analysis and guidelines have been provided to the MFBs and MFIs to increase their outreach. The sector is financially unstable which is attributable to its reliance on conventional sources of funding. The industry faces several endogenous as well as exogenous challenges from its environment which obstructs its growth. Further, it helps the policymakers to work on the development of the region and provide the base for further future research work.