• Journal of the Korea Concrete Institute
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• v.17 no.1 s.85
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• pp.51-58
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• 2005

Moment frames have been widely used in building construction. In current design codes, concrete moment frames are classified into ordinary, intermediate, and special moment resisting concrete frames (OMRCF, IMRCF, SMRCF)). The objective of this study is to investigate the seismic behavior of columns in ordinary moment resisting concrete frames (OMRCF) and intermediate moment resisting concrete frames (IMRCF). For this purpose 3 story OMRCF and IMRCF buildings were designed and detailed in compliance to ACI 318 (2002) and KCI (1999). In this study the buildings were assumed to be located in seismic zone 1 classified by UBC (1997). This study considered the columns in the 1st story since these columns shall resist the largest axial and lateral forces during an earthquake. Eight 2/3 scale column specimens were made for representing the upper part and lower part of exterior and interior columns of the OMRCF and the IMRCF Quasi-static reversed cyclic loading was applied to each specimen with a constant or varying axial load. Test results show that seismic behaviors of columns are influenced by existence of lap splices, axial force levels, and lateral reinforcement at possible plastic hinging region. However, the effect of such variables strongly co-related to each other.

• Journal of the Korea Concrete Institute
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• v.17 no.5 s.89
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• pp.673-678
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• 2005

ACI 318 (1999) defines three types of moment frames: Ordinary Moment Resisting Concrete Frame (OMRCF), Intermediate Moment Resisting Concrete Frame (IMRCF), and Special Moment Resisting Concrete Frame (SMRCF). OMRCF is the most popular type of moment frame in mild seismic zones that requires the least detail and design requirements. This study focuses on the seismic performance of Ordinary Moment Resisting Concrete Frames (OMRCF) designed only for gravity loads. For this purpose a 3-story OMRCF was designed in compliance with the minimum design requirements in ACI 318 (1999). An one third 3 story specimen was made and tested. For scaled model, the similitude law of true replica was applied. The specimen was loaded with quasi-static reversed cyclic lateral loading. The overall behavior of OMRCF is quite stable without abrupt strength degradation. It is found that tested frame has the base shear strength larger than the design base shear for seismic zone 1, 2A and 2B calculated using UBC 1997.

• Korean Institute of Interior Design Journal
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• v.26 no.2
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• pp.72-82
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• 2017

Current world population is rapidly ageing and the disabled population is expected to age seriously as well. The concern about the elderly and the disabled is increased largely not just the field of social welfare and service but the housing planning where the physical environment of everyday life is. Recently in Ireland, 'Universal Design Guideline for Homes' is established and proposed in public. It is considered as initial and special national policy for the socially venerable. The purpose of this research is to analyze the User Benefit Characteristics(UBC) of 'Universal Design Guideline for Homes in Ireland' and clearly organize the characteristics for comprehensive communication. The research subjects are 444 guidelines of 'Universal Design Guideline for Homes in Ireland.' The research is conducted by contents analysis technique, and each guideline is analyzed by the 4 main concepts of UBC- 'Behavioral Facilitation(BF)', 'Physiological Maintenance(PhM)', 'Perceptual Maintenance(PM)', 'Social Facilitation(SF).' As results, the User Benefit Characteristic of 'Universal Design Guideline for Homes in Ireland' is ordered by PhM>PM>BF>SF. The design guidelines are supposed to support ageing in place and sustainable living in the existing houses even though people are ageing or being disabled. 'Universal Design Guideline for Homes in Ireland' supports safe behavior and comfort cognition especially in indoor and surrounding outdoor environment. This research is significant for sharing the knowledge and comprehension of decreasing environmental stress of the elderly in specific, and could be utilized for developing new elderly housing in future.

• 한국태양에너지학회:학술대회논문집
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• 2009.04a
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• pp.102-108
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• 2009

Fossil power plants firing lower grade coals or equipped with modified system for NOx controls are challenged with maintaining good combustion conditions while maximizing generation and minimizing emissions. In many cases significant derate, availability losses and increase in unburned carbon levels can be attributed to poor combustion conditions as a result of poorly controlled local fuel and air distribution within the boiler furnace. In order to develop a on-line combustion tuning system, field test was conducted at operating power boiler. During the field test the exhaust gases' $O_2$, NOx and CO was monitored by using a spatially distributed monitoring grid located in the boiler's high temperature vestibule and upper convective back-pass region. At these locations, the flue gas flow is still significantly stratified, and air in-leakage is minimal which enables tracing of poor combustion zones to specific burners and over-fire air ports. using these monitored information we can improving combustion at every point within the furnace, therefore the boiler can operate at reduced excess $O_2$ and gas temperature deviation, reduced furnace exit gas temperature levels while also reducing localized hot spots, corrosive gas conditions, slag or clinker formation and UBC. Benefits include improving efficiency, reducing NOx emissions, increasing output and maximizing availability. Discussion concerning the reduction of greenhouse gases is prevalent in the world. When taking a practical approach to addressing this problem, the best way and short-term solution to reduce greenhouse gases on coal-fired power plants is to improve efficiency. From this point of view the real time optimized combustion tuning approach is the most effective and implemented with minimal cost.

• BMB Reports
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• v.47 no.4
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• pp.233-238
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• 2014

Polypyrimidine tract-binding protein 1 (PTBP1) and its brain-specific homologue, PTBP2, are associated with pre-mRNAs and influence pre-mRNA processing, as well as mRNA metabolism and transport. They play important roles in neural differentiation and glioma development. In our study, we detected the expression of the two proteins in glioma cells and predicted that they may be sumoylated using SUMOplot analyses. We confirmed that PTBP1 and PTBP2 can be modified by SUMO1 with co-immunoprecipitation experiments using 293ET cells transiently co-expressing SUMO1 and either PTBP1 or PTBP2. We also found that SUMO1 modification of PTBP2 was enhanced by Ubc9 (E2). The mutation of the sumoylation site (Lys137) of PTBP2 markedly inhibited its modification by SUMO1. Interestingly, in T98G glioma cells, the level of sumoylated PTBP2 was reduced compared to that of normal brain cells. Overall, this study shows that PTBP2 is posttranslationally modified by SUMO1.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.11
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• pp.6375-6378
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• 2013

Background: The glutathione S transferase (GST) family of enzymes plays a vital role in the phase II biotransformation of environmental carcinogens, pollutants, drugs and other xenobiotics. GSTs are polymorphic and polymorphisms in GST genes have been associated with cancer susceptibility and prognosis. GSTP1 is associated with risk of various cancers including bladder cancer. A case control study was conducted to determine the genotype distribution of GSTP1 A>G SNP, to elucidate the possible role of this SNP as a risk factor in urinary bladder cancer (UBC) development and to examine its correlation with clinico-pathologic variables inUBC cases. Materials and Methods: Using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) approach, we tested the genotype distribution of 180 bladder cancer patients in comparison with 210 cancer-free controls from the same geographical region with matched frequency in age and gender. Results: We did not observe significant genotype differences between the control and bladder cancer patients overall with an odds ratio (OR)=1.23 (p>0.05). The rare allele (AG+GG) was found to be present more in cases (28.3%) than in controls (24%), though the association was not significant (p<0.05). However, a significant risk of more than 2-fold was found for the variant allele (AG+GG) with smokers in cases as compared to controls (p>0.05). Conclusions: Thus, it is evident from our study that GSTP1 SNP is not implicated overall in bladder cancer, but that the rare, valine-related allele is connected with higher susceptibility to bladder cancer in smokers and also males.

• Journal of the Korean Solar Energy Society
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• v.29 no.5
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• pp.45-52
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• 2009

Fossil power plants firing lower grade coals or equipped with modified system for $NO_x$ controls are challenged with maintaining good combustion conditions while maximizing generation and minimizing emissions. In many cases significant derate, availability losses and increase in unburned carbon levels can be attributed to poor combustion conditions as a result of poorly controlled local fuel and air distribution within the boiler furnace. In order to develop a on-line combustion tuning system, field test was conducted at operating power boiler. During the field test the exhaust gases' $O_2,\;NO_x$ and CO was monitored by using a spatially distributed monitoring grid located in the boiler's high temperature vestibule and upper convective rear pass region. At these locations, the flue gas flow is still significantly stratified, and air in-leakage is minimal which enables tracing of poor combustion zones to specific burners and over-fire air ports. using these monitored information we can improving combustion at every point within the furnace, therefore the boiler can operate at reduced excess $O_2$ and gas temperature deviation, reduced furnace exit gas temperature levels while also reducing localized hot spots, corrosive gas conditions, slag or clinker formation and UBC. Benefits include improving efficiency, reducing $NO_x$ emissions, increasing output and maximizing availability. Discussion concerning the reduction of greenhouse gases is prevalent in the world. When taking a practical approach to addressing this problem, the best way and short-term solution to reduce greenhouse gases on coal-fired power plants is to improve efficiency. From this point of view the real time optimized combustion tuning approach is the most effective and implemented with minimal cost.

• Korean Journal of Plant Resources
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• v.14 no.1
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• pp.65-70
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• 2001

This study was performed to select marker which can identify genetic variation between mother plant and in vitro cultured plantlets of strawberry by PCR using random primer. When 'Yeobong' DNA extracted was treated with proteinase-K and RNase-H, clear DNA bands were shown. The optimal condition for RAPD in strawberry was to use 50ng of template DNA, 10pmol of primer,37oC of annealing temperature, and 45 cycles of PCR. After establishing above PCR optimal condition, RAPD pattern was investigated by using UBC primers. PCR was performed, and 46 of 90 primers produced PCR product showing 158 total bands. GC content was compared between the primers forming bands and no bands. The GC content showing bands was average 67.4%, whereas primers showing no bands 58%.

• Resources Recycling
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• v.9 no.2
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• pp.46-52
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• 2000

Aluminum can to can recycling was divided into two stpes. The first step was composed of the processes such as collection of used beverage cans (UBC), shredding, magnetic separation, De-laquiring, melting and casting. The second one was remelting and casting, heat treating, hot and cold rolling, annealing, and can making. In this study, the effect of alloying elements on the microstructure and texture of the secondary ingots made by Al UBC was investigated. In aluminum can to can recycling, the second phase particles appeared in the solidification stage must be controlled by heat treatment. The optimum heat treatment condition was $615^{\circ}C$ for 5hrs. the texture in hot rolled sheet was depressed with increasing Mn content, on the other hand, Si and Fe elements promoted the texture development. The textures of can-body sheet should be controlled in the hot rolling and annealing stage because can was formed from cold rolled sheet without heat treatment.

• Molecules and Cells
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• v.26 no.1
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• pp.5-11
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• 2008

Stalled DNA replication forks activate specific DNA repair mechanism called post-replication repair (PRR) pathways that simply bypass DNA damage. The bypassing of DNA damage by PRR prevents prolonged stalling of DNA replication that could result in double strand breaks (DSBs). Proliferating cell nuclear antigen (PCNA) functions to initiate and choose different bypassing pathways of PRR. In yeast, DNA replication forks stalled by DNA damage induces monoubiquitination of PCNA at K164, which is catalyzed by Rad6/Rad18 complex. PCNA monoubiquitination triggers the replacement of replicative polymerase with special translesion synthesis (TLS) polymerases that are able to replicate past DNA lesions. The PCNA interaction motif and/or the ubiquitin binding motif in most TLS polymerases seem to be important for the regulation of TLS. The TLS pathway is usually error-prone because TLS polymerases have low fidelity and no proofreading activity. PCNA can also be further polyubiquitinated by Ubc13/ Mms2/Rad5 complex, which adds an ubiquitin chain onto monoubiquitinated K164 of PCNA. PCNA polyubiquitination directs a different PRR pathway known as error-free damage avoidance, which uses the newly synthesized sister chromatid as a template to bypass DNA damage presumably through template switching mechanism. Mammalian homologues of all of the yeast PRR proteins have been identified, thus PRR is well conserved throughout evolution. Mutations of some PRR genes are associated with a higher risk for cancers in mice and human patients, strongly supporting the importance of PRR as a tumor suppressor pathway.