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Effects of Ukgansan Pharmacopuncture at GB20 on Cognitive Impariment Induced by Focal Brain Injury in Rats (풍지(風池)(GB20) 억간산(抑肝散) 약침이 국소 뇌손상으로 유발된 흰쥐의 인지장애에 미치는 영향)

  • Lee, Jung Hun;Yang, Tae Jun;Jeong, Sang Jun;Wei, Tung Shuen
    • Journal of Acupuncture Research
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    • v.33 no.3
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    • pp.101-116
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    • 2016
  • Objectives : This research was performed to investigate the effects of Ukgansan pharmacopuncture(U-PA) of focal brain ischemia induced by middle cerebral artery occlusion(MCAO) in rats. Methods : The subjects were divided into 5 groups : A control group, acupuncture group, pharmacopuncture group U-PA1($2.571mg/250g/40{\mu}{\ell}$), pharmacopuncture group U-PA2($6.428mg/250g/40{\mu}{\ell}$), and pharmacopuncture group U-PA3($12.855mg/250g/40{\mu}{\ell}$). The focal brain ischemia was induced by intraluminal filament insertion into the middle cerebral artery. After 3 days of MCAO, Ukgansan(UGS) pharmacopuncture treatment was performed on the GB20, and the day after being treated with pharmacopuncture, the Morris water maze test was carried out by the assigned group. The series of processes were treated 6 times. Thereafter Bax, Bcl-2, Bax/Bcl-2 ratio, mGluR5, density of neuronal cell, and ChAT were measured. Results : The results were as follows. 1. The intensity of Bax significantly decreased in the U-PA1, U-PA2, U-PA3 groups. 2. The Bax/Bcl-2 ratio significantly decreased in the U-PA3 group compared with the control group. 3. The neuroprotective effect on the hippocampal CA1 significantly increased in the U-PA1, U-PA2, U-PA3 groups compared with the control group. 4. The density of ChAT in the hippocampal CA1 significantly increased in the U-PA1, U-PA2, U-PA3 groups compared with the control group. Conclusion : These results suggest that UGS pharmacopuncture may have anti-apoptotic and neuroprotective effects on focal cerebral ischemia caused by intraluminal filament insertion into the middle cerebral artery in rats.

Beam Steering Antenna Using Microstrip Patch with U-Slot for Wearable Fabric Applications (의복용 U-슬롯을 갖는 빔 조향 마이크로스트립 안테나)

  • Ha, Sang-Jun;Jung, Chang-Won
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.22 no.8
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    • pp.754-760
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    • 2011
  • Reconfigurable beam steering using microstrippatch antenna with U-slot is proposed for wearable fabric applications. The proposed antenna is manufactured on a fabric substrate, and designed to steer the beam directions at the operation frequency of 6.0 GHz. The U-shaped slot and the indirect feeding-techniques are utilized in designing the proposed antenna. By the configuration of two artificial switches($S_0$, $S_1$, $S_2$) in between the indirect feed and the antenna patch, the antenna has three beam directions. The maximum beam directions are steerable in the yz-plane(${\theta}=0^{\circ}$, $30^{\circ}$, $331^{\circ}$), and the overall HPBW is $115^{\circ}$. The measured peak gains are 6.11~6.69 dBi.

The Economic and non-Economic Analysis of U.S.-China Trade Deficits

  • MA, Shuqin
    • International Commerce and Information Review
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    • v.6 no.3
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    • pp.373-384
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    • 2004
  • While the bilateral trade volume between China and U.S. has been growing rapidly, the trade deficits of U.S. to China has also been expanding. This growing trade deficit of U.S. to China has several reasons: the increase of foreign direct investment to China, the transfer of trade deficit origins, the intervention of U.S. domestic politics to China-U.S. trade relations, and U.S. direct control on export to China. However, the increased U.S. trade deficit to China does not mean that U.S. is in a disadvantaged position in its economic relations with China, or its international competitiveness is deteriorating. When U.S. surplus in service trade to China is included, the picture would be very different. Also, as internationalization progresses and China's industrial structure adjusts, the trade deficit of U.S. to China would narrow.

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Directivity Gain Improvement Method for UWB Coplanar Patch Antenna (UWB 평면 패치안테나의 지향성이득의 향상 방법)

  • Joo, Chang-Bok
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.49 no.6
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    • pp.63-70
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    • 2012
  • This paper discussed on the directive gain improvement method of the U-type ultra wide-band(UWB) planar patch antenna model with CPW feeding. For directive gain improvement, the U-type printed patch antenna model with CPW feeding is reconstructed as a microstrip structure by adding a reflection plane with aperture slot. The reflection coefficient of the reconstructed antenna is less than -6.5 dB(VSWR < 3.3) to the characteristic impedance of $50.08{\Omega}$ and showed the directive radiation patterns with the directive gain of 7.5 dBi ~ 10.1 dBi, the front-back ratio of 17.8 dB ~ 28.7 dB and the range of -3dB radiation angle over ${\pm}30^{\circ}$ to the main beam direction of ${\theta}=0^{\circ}$.

Effects of Formaldehyde/Urea Molar Ratio on Bonding Strength of Plywood and Properties of Sliver-PB and Strand-PB (F/U 몰비의 변이가 합판의 접착성과 Sliver-PB, Strand-PB의 물성에 미치는 영향)

  • Park, Heon;You, Young-Sam
    • Journal of the Korean Wood Science and Technology
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    • v.27 no.2
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    • pp.38-45
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    • 1999
  • This study was to figure out proper Formaldehyde/Urea molar ratio of UF resin with satisfactory bonding strength of plywood and properties of particleboard. The six kinds of UF resins were manufactured with F/U molar ratio 1.0, 1.2, 1.4, 1.6, 1.8, and 2.0. The boards were made of three kinds of raw materials : Veneer, Sliver-Particle and Strand-Particle. Manufacturing condition of plywood : amount of mixing resin was 150g/$m^2$. The fourty secs/mm simple-pressing schedule in the pressure 10kgf/$m^2$ was applied for 480mm${\times}$700mm board at the temperature of $110^{\circ}C$ in a hot press. Manufacturing condition of particleboard : Target density was 0.65g/$cm^2$. The stepwise 9 minutes- multi-pressing schedule in the maximum pressure 40kgf/$cm^2$, the minimum pressure 15kgf/$cm^2$ was applied for $480mm{\times}634mm{\times}12mm$ board at the temperature of $150^{\circ}C$ in a hot press. The results are as follows : I. In bonding strength, plywood which was made by F/U molar ratio 1.2 showed the highest value. Other molar ratio resin also gave the satisfied value of KS standard, 7.5kgf/$cm^2$. 2. In internal bond strength of particleboard, Sliver-Particleboard(SLPB) and Strand-Particleboard(STPB) varied respectively from 5.9kgf/$cm^2$ to 4.8kgf/$cm^2$, from 6.7kgf/$cm^2$ to 5.4kgf/$cm^2$. SLPB with F/U=1.2 and STPB with F/U=1.6 had higher IB value. Also, both SLPB and STPB showed lower IB value in F/U molar ratio 2.0 and 1.0. 3. SLPB and STPB with six kinds of UF resin respectively satisfied bending strength of KS standard 150 Type(130kgf/$cm^2$) and 200 Type(180kgf/$cm^2$). Bending strength data for both of SLPB and STPB showed little or no loss from F/U=1.8 to F/U=1.2. Also, STPB was approximately two times higher than that of SLPB. Therefore, the raw material's shape had more effect on bending strength than the FlU molar ratio. 4. F/U=1.6 and 1.4 showed the lower thickness swelling in SLPB and STPB. All of STPBs satisfied thickness swelling of KS standard, under 12%.

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Serial Changes of Serum Thyroid-Stimulating Hormone after Total Thyroidectomy or Withdrawal of Suppressive Thyroxine Therapy in Patients with Differentiated Thyroid Cancer (분화성 갑상선 암 환자에서 갑상선 전절제술후 또는 갑상선 호르몬 억제 요법 중단에 따른 갑상선 자극호르몬의 변화)

  • Bae, Jin-Ho;Lee, Jae-Tae;Seo, Ji-Hyoung;Jeong, Shin-Young;Jung, Jin-Hyang;Park, Ho-Yong;Kim, Jung-Guk;Ahn, Byeong-Cheol;Sohn, Jin-Ho;Kim, Bo-Wan;Park, June-Sik;Lee, Kyu-Bo
    • The Korean Journal of Nuclear Medicine
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    • v.38 no.6
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    • pp.516-521
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    • 2004
  • Background: Radioactive iodine (RAI) therapy and whole-body scanning are the fundamentals of treatment and follow-up of patients with differentiated thyroid cancer. It is generally accepted that a Thyroid-Stimulating Hormone (TSH) level of at least 30 ${\mu}U/ml$ is a prerequisite for the effective use of RAI, and that it requires 4-6 weeks of off-thyroxine to attain these levels. Because thyroxine withdrawal and the consequent hypothyroidism are often poorly tolerated, and occasionally might be hazardous, it is important to be certain that these assumptions are correct. We have measured serial changes in serum TSH after total thyroidectomy or withdrawl of thyroxine in patients with thyroid cancer. Subjects and Methods: Serum TSH levels were measured weekly after thyroidectomy in 10 patients (group A) and after the discontinuation of thyroxine in 12 patients (group B). Symptoms and signs of hypothyroidism were also evaluated weekly by modified Billewicz diagnostic index. Results: By the second week, 78% of group A patients and 17% of group B patients had serum TSH levels ${\geq}30{\mu}U/ml$. By the third week, 89% of group A patients and 90% of group B patients had serum TSH levels ${\geq}30{\mu}U/ml$. By the fourth week, all patients in two groups achieved target TSH levels and there were no overt hypothyroidism. Conclusion: in all patients, serum TSH elevated to the target concentration (${\geq}30{\mu}U/ml$) within 4 weeks without significant manifestation of hypothyroidism. The schedule of RAI administration could be adjusted to fit the needs and circumstances of individual patients with a shorter preparation period than the conventional.

Comparison of Saccharina japonica-Undaria pinnatifida Mixture and Minoxidil on Hair Growth Promoting Effect in Mice

  • Park, Ki Soo;Park, Dae Hwan
    • Archives of Plastic Surgery
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    • v.43 no.6
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    • pp.498-505
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    • 2016
  • Background Algae have traditionally been used for promotion of hair growth. Use of hair regrowth drugs, such as minoxidil, is limited due to side effects. The aim of this study was to examine a mixture of Saccharina japonica and Undaria pinnatifida (L-U mixture) on hair growth and to compare the promoting effect of hair growth by a 3% minoxidil and a L-U mixture. Methods To evaluate the hair growth-promoting activity, saline, 50% ethanol, 3% minoxidil, and the L-U mixture were applied 2 times a day for a total of 14 days on the dorsal skin of C57BL/6 mice after depilation. Analysis was determined by using a high-resolution hair analysis system, real-time polymerase chain reaction, and H&E staining. Results On day 14, the hair growth effect of the L-U mixture was the same as that of the 3% minoxidil treatment. The L-U mixture significantly (P<0.05) stimulated hair growth-promoting genes, as vascular endothelial growth factor (VEGF) and insulin-like growth factor -1. Increase of VEGF was observed in the L-U mixture group compared with minoxidil and the negative control. In contrast, the L-U mixture suppressed the expression of transforming growth factor-${\beta}1$, which is the hair loss-related gene. In histological examination in the L-U mixture and minoxidil groups, the induction of an anagen stage of hair follicles was faster than that of control groups. Conclusions This study provides evidence that the L-U mixture can promote hair growth in mice, similar to the effect from minoxidil, and suggests that there is potential application for hair loss treatments.

Performance Analysis of Smartphone based u-NMS (스바트폰 기반의 u-NMS 성능 분석)

  • Kim, Chae-Hwan;Sohn, Woo-Jin;Lee, Kyung-Geun
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.36 no.6B
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    • pp.608-617
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    • 2011
  • ubiquitous network management system (u-NMS) is the network management system based on smartphone which are recently of wide use. The purpose of the u-NMS is to provide convenience for network administrator utilizing the mobility of smartphone and to manage the network efficiently. This paper proposes the smart NMS agent and the mobility management server (MMS). The smart NMS agent enables to use the monitoring web server and remote control application on the smartphone in wireless network. The MMS is developed to reduce the problems such as handover latency and packet loss, which can be taken place in wireless network. The network manager can monitor traffic in real time through the smart NMS agent and remotely control the network efficiently when sudden failures happen in the u-NMS. In this paper, performance evaluation is carried out with our test-bed system implemented. We focus on the measurement of the MMS performance. When the MMS is compared to previous mobility management protocol, our mobility management server reduces the average latency up to 65% in initial access, handover latency and processing delay to the network management center.

Mechanism of RFID Authentication for u-Vehicle (u-Vehicle 환경에 적합한 RFID 인증 메커니즘)

  • Rhee, Yoon-Jung;Kim, Do-Hyeon
    • The Journal of the Korea Contents Association
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    • v.8 no.6
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    • pp.66-73
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    • 2008
  • The concept of u-Vehicle is a technological model that people try to build the ubiquitous world in the car which moves, by using the RFID technology as well as the telematics service based on the location. RFID is weak on the point of information security because RFID has possibility for being abused such as chasing, counterfeiting, and invading personal privacy. RFID's tags use a weak cryptographic algorithm. This paper presents the vulnerabilities of information security under u-Vehicle environments. To solve that, we propose a mechanism enhancing RFID tag's security but with low cost by reducing the number of mutual authentication stages and using the hash function.