• Proceedings of the Korean Nuclear Society Conference
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• 1997.05a
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• pp.484-488
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• 1997

Fission product release (FPR) assessment for 100% reactor outlet header (ROH) break in CANDU reactor loaded with CANFLEX-NU fuel bundles has been performed. The predicted results are compared with those for the reactor loaded with standard 37-element bundles. The fuel failure thresholds for the CANFLEX and standard bundle elements are very similar. All the sheaths at the corresponding fuel failure thresholds for the CANFLEX and standard bundles fail due to the significant cracks in the surface oxide, except those for the CANFLEX inner element at burnups of 220 to 240 MW.h/kg(U), which fail due to the excessive diametral strain. The fuel failure analysis predicts that the number of failed fuel elements for the CANFLEX bundle case is none, while that for the standard bundle case is 1827. The total (gap plus bound) I-131 releases for the CANFLEX and standard bundles are none and 5889 TBq, respectively The significant reduction of the number of failed fuel elements and FPR for the CABFKEX fuel bundle is attributed to the lower linear power of the CANFLEX fuel bundle compared with the standard fuel bundle.

• International Journal of Precision Engineering and Manufacturing
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• v.1 no.1
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• pp.133-145
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• 2000

Plastic molding designers are frequently faced with optimizing multiple defects in injection molded parts. these defects are usually in conflict with each other, and thus a tradeoff needs to be made reach a final compromised solution. In this study, an automated injection molding design methodology has been developed to optimize multiple defects of injection molded parts. Two features of the proposed methodology are as follows: one is to apply the utility theory to transform the original multiple objective optimization problem into single objective optimization problem with utility as objective function, the other is an implementation of a direct search-based injection molding optimization procedure with automated consideration of process variation. The modified complex method is used as a general optimization tool in this research. The developed methodology was applied to an actual molding design and the results showed that the methodology was useful through the CAE simulation using a commercial injection molding software package. Applied to production, this study will be of immense value to industry in reducing the product development time and enhancing the product quality.

• Proceedings of the KSRS Conference
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• v.1
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• pp.512-515
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• 2006

Forest stand height and volume are important indicators for management purpose as well as for the environmental analysis. Shuttle Radar Topography Mission (SRTM) is backscattered over forest canopy and DSM can be acquired from such scattering characteristic, while National Elevation Dataset (NED) provides bare earth elevation data. The difference between SRTM and NED is estimated as tree height, and it is correlated with forest parameters, it is correlated with forest parameters, including average DBH, Trees per acre, net BF per acre, and total Net MBF. Especially, among them, net Board Foot(BF) per acre is the index that well represents forest volume. The Project site was Douglas-fir dominating plantation area in the western Washington an the northern Oregon in the U.S. This study shows a relationship of high correlation between the forest parameters and the product from SRTM, NED, and ETM+. This research performs multi regression analysis and regression tree algorithm, and can get more improved relationship between several parameters.

• Transactions of Materials Processing
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• v.15 no.4 s.85
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• pp.295-303
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• 2006

Optimization is carried out to determine process parameters which reduce the amount of springback and improve shape accuracy of a deep drawn product in sheet metal forming process. The study uses the amount of stress deviation along the thickness direction in the deep drawn product as an indicator of springback instead of springback simulation. The scheme incorporates with an explicit elasto-plastic finite element method for calculation of the final shape and the stress deviation The optimization method adopts the response surface method in order to seek for the optimum condition of process parameters such as the blank holding force and the draw-bead force. The present scheme is applied to design of the variable blank holding force in an U-draw bending process and the application is further extend ε d to the design of draw-bead force in a front side member formed with advanced high strength steel (AHSS) sheets of DP60. Results show that design of process parameter is well performed to decrease the stress deviation through the thickness and to reduce the amount of springback. The present analysis provides a guideline in a design stage for controlling the springback based on the finite element simulation of the complicated parts.

• Journal of the East Asian Society of Dietary Life
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• v.6 no.2
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• pp.277-284
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• 1996

The objective of this study was to screen the antimutagenicity of yam enzymatic browning reaction product (YEBRP), mucopolysaccharide and dietary fiber from yam to the mutagen of sodium azide and 2-aminoflourene (2-AF). Antimutagenicity of YEBRP on the mutagenicity of sodium azide showed no difference compared to control without YEBRP but that of 2-AF was high In all substrate. (P＜0.01) On the mutagenicity of sodium azide and 2-AF, antimutagenicity of mucopolysaccharide and dietary fiber were high (p＜0.01) in $\alpha$-cellulose and hemicellulose, Antimutagenicity of u-cellulose on the mutagenicity of 2-AF was high at 5 hours reaction time but that was decreased as the reaction time increased.

• Transactions of Materials Processing
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• v.25 no.1
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• pp.21-28
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• 2016

In the current study, reduction of springback is quantified and the reasons for the reduction are investigated. The testing involved a digital servo motion applied to a U-draw bending to produce a hat-type product from high strength steels such as DP780 and DP980. The change in springback is compared between the constant speed motion and three kinds of servocontrolled motions during forming experiments. In order to predict the springback for the servo-controlled tool motion, a finite element method was utilized for the springback analysis considering a kinematic hardening model for the steel. The comparison of springback between the analysis and the experiments shows that they have similar tendencies. Also, the analysis results indicate that the springback reduction is greatly influenced by a decrease in the friction coefficient, which originates from the contact and detach phenomena between the tooling and the blank during the up-and-down motion of the upper die following the servo-controlled motion.

• Journal of Korean Public Health Nursing
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• v.9 no.2
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• pp.104-114
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• 1995

This study was designed to develop preventing occupational disease programme in small-medium scale industries. The intervention was done in 354 enterprises from July to December in 1993 by health personnels in mobile occupational health centers. The summarized results of the above achievements were as follows. 1. Total number of enterprises were 354. Among them $66.9\%$ was under 100 workers, $26.6\%$ was u!1der 200 workers, and $6.5\%$ was belong to over 200 workers. The majority manufactures were non-metallic mineral product industries $(11.3\)$ fabricated metal product industries $(11.0\%)$. and textile industries $(10.7\%)$. 2. In 1993, for 350 enterprises were carried out evaluation of workplace environment. A total of $76.3\%$ industries were found to improper showing higher level of hazardous agent than the TLV. Noise and dust are the typical agent of which levels in workplace were high in most of industries. 3. A total 60 cases $(0.8\%)$ of occupational diseases were detected through physical check-up from 7,394 industrial workers in 1993. Detection rate by hazardous agent was highest among workers in relation to dust, and secondly highest to noise. 4. Through the systematic approach by hazardous agent was increased to the monitoring of work condition and follow up care of occupational disease. In future, there should be development in the scaled check list of preventing occupational disease management.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.7
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• pp.4235-4238
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• 2013

Glucoraphanin is the main glucosinolate found in broccoli and other cruciferous vegetables (Brassicaceae). The objective of the study was to evaluate whether glucoraphanin and its breakdown product sulforaphane, are potent modulators of various phase I and phase II enzymes involved in carcinogen-metabolising enzyme systems in vitro. The glucosinolate glucoraphanin was isolated from cruciferous vegetables and exposed to human hepatoma cell line HepG2 at various concentrations (0-25 ${\mu}M$) for 24 hours. Glucoraphanin at higher concentration (25 ${\mu}M$) decreased dealkylation of methoxyresorufin, a marker for cytochrome P4501 activity; supplementation of the incubation medium with myrosinase (0.018 U), the enzyme that converts glucosinolate to its corresponding isothiocyanate, showed minimal induction in this enzyme activity at concentration 10 ${\mu}M$. Quinone reductase and glutathione S-transferase activities were unaffected by this glucosinolate; however, supplementation of the incubation medium with myrosinase elevated quinone reductase activity. It may be inferred that the breakdown product of glucoraphanin, in this case sulforaphane, is superior than its precursor in modulating carcinogen-metabolising enzyme systems in vitro and this is likely to impact on the chemopreventive activity linked to cruciferous vegetable consumption.

• Molecules and Cells
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• v.28 no.4
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• pp.397-401
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• 2009

Flavonoids are a group of polyphenolic compounds that have been recognized as important due to their physiological and pharmacological roles and their health benefits. Glycosylation of flavonoids has a wide range of effects on flavonoid solubility, stability, and bioavailability. We previously generated the E. coli BL21 (DE3) ${\Delta}pgi$ host by deleting the glucose-phosphate isomerase (Pgi) gene in E. coli BL21 (DE3). This host was further engineered for whole-cell biotransformation by integration of galU from E. coli K12, and expression of calS8 (UDP-glucose dehydrogenase) and calS9 (UDP-glucuronic acid decarboxylase) from Micromonospora echinospora spp. calichensis and arGt-4 (7-O-glycosyltransferase) from Arabidopsis thaliana to form E. coli (US89Gt-4), which is expected to produce glycosylated flavonoids. To test the designed system, the engineered host was fed with naringenin as a substrate, and naringenin 7-O-xyloside, a glycosylated naringenin product, was detected. Product was verified by HPLC-LC/MS and ESI-MS/MS analyses. The reconstructed host can be applied for the production of various classes of glycosylated flavonoids.

• Journal of Microbiology
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• v.41 no.4
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• pp.295-299
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• 2003

Adenovirus (Ad) precursor to the terminal protein (pTP) plays an essential roles in the viral DNA replication. Ad pTP serves as a primer for the synthesis of a new DNA strand during the initiation step of replication. In addition, Ad pTP forms organized spherical replication foci on the nuclear matrix (NM) and anchors the viral genome to the NM. Here we identified the interferon inducible gene product 1-8D (Inid) as a pTP binding protein by using a two-hybrid screen of a HeLa cDNA library. Of the clones obtained in this assay, nine were identical to the Inid, a 13-kDa polypeptide that shares homology with genes 1-8U and Leu-13/9-27, most of which have little known functions. The entire open reading frame (ORF) of Inid was cloned into the tetracycline inducible expression vector in order to determine the biological functions related with adenoviral infection. When Inid was introduced to the cells along with adenoviruses, fifty to sixty percent of Ad-infected cells expressing Inid had rounded morphology, which was suggestive of apoptosis. Results from the terminal deoxynucleotidyl transferase (TdT) and DNA fragmentation assays confirmed that Inid induces apoptosis in Ad-infected or in uninfected cells. The Inid binding to pTP may target the cell for apoptotic destruction as a host defense mechanism against the viral infection.