• Nutrition Research and Practice
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• v.1 no.2
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• pp.100-104
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• 2007

Saururus chinensis Baill was reported to inhibit ${\alpha}-glucosidase$ in vitro and flatten postprandial increase in blood glucose in streptozotocin (STZ)-induced diabetic rats. We studied the effect of chronic consumption of S. chinensis Baill on blood glucose and lipid profile in STZ-induced diabetic male rats fed high fat diet. Male rats weighing 100-120 g were fed 30% fat diet with and without 10% freeze-dried leaves of S. chinensis Baill for 7 weeks after 1 week of adaptation. The rats were rendered diabetic by intravenous injection of STZ (60 mg/kg) after 6-week feeding of the assigned diets. At 1 week after the injection, the rats were sacrificed after an overnight fast. Plasma glucose ($380.2{\pm}14.4mg/dL$), total cholesterol ($93.9{\pm}7.9mg/dL$) and triglyceride levels ($123.6{\pm}7.5mg/dL$) of the S. chinensis Baill group were significantly lower than those of the control group ($418.1{\pm}12.0mg/dL,\;119.9{\pm}9.4mg/dL,\;152.0{\pm}10.3mg/dL$, respectively, p<0.05). Chronic consumption of S. chinesis Baill significantly decreased maltase activity of the small intestinal mucosa ($120.1{\pm}8.7U/g$) protein compared with the control group ($96.8{\pm}7.0U/g protein, p<0.05). These results suggest that S. chinensis Baill have hypoglycemic and hypolipidemic effects by inhibiting ${\alpha}-glucosidase$ activity in the animal model of diabetes mellitus.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.25 no.1
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• pp.1-12
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• 2015

Objectives: The major objectives of this study are to review the U.S. Standard which affected Korean worker's Right-to-Know Standard and to propose the way of improving the reliability of MSDS and labels. Methods: To review the U.S. Standard historically, we used the Federal Register, other criteria documentation and peer-reviewed literatures. Then we analysed major issues in the historical debatement on the worker's Right-to-Know Standard. Results: Korean MSDS Standard benchmarked the U.S. Hazard Communication Standard which finally established by President Reagan in 1983. Reagan's Hazard Communication Standard was aimed to preempt States Right-to-Know Acts for chemical industry and not to improve the awareness of workers on chemical hazards. Too much protection on trade secrets and low reliability of hazard information were key problems of the U.S. Standard. Conclusions: We recommend some ways to improve Korean MSDS and Label Standard. First, A new analysis frame is needed to understand the U.S Standard. Second, hazard identification is the key element of reliable information and chemical name and CAS number should be on the label of the container. Third, trade secrets should be limited to low hazardous substances and be permitted by government before the chemical product is on the market.

• Archives of design research
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• no.16
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• pp.1-14
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• 1996

As the marketing strategy of corporations has been changing in various ways, the type of new product development has also bC'en changing in dim~rent ways. The types of changes include, among oiller things, product development. wit.h a new concept., revolut.ionary product development., new brand product. development., improvement. of existing product. and development. in model changes. The design development has similarly advanced with the growth in scient.ific approach in t11e design process of new product. development. in relat.ion t.o each t.ype of product development.. Ilowever, in view of the design approach or st.rat.egy for each t.ype, different. kinds of method of development is necessary. In order to increase t.he life cycle of an existing product. which has reached its mature stage and to respond t.o the changes 111 time t.hrough product improvement., it is becoming more imtxJrl.ant for Ule corporation to confonn wiU1 the changes in time by being able to sat.isfy the consumer! s needs, way of thinking and luxury inclination by utilizing the changes in design. However, it is very difficult to decide on a design using different development. methods which would clearly meet such neL'

• Applied Chemistry for Engineering
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• v.9 no.2
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• pp.232-237
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• 1998

This study was carried out to find the optimal operating conditions for separation of residual uranium from the simulated radwaste solution containing 19 elements, and to evaluate the validity of the process. The selected process was based on the solvent extraction with TBP(tributyl phosphate). As an extractor, two miniature mixer-settlers with a total of 18 stages were used. Extraction yield of U, Np and Tc was about 99.2%. 32.1%, and 99.9%, respectively. The other elements were coextracted in the range of 1~4%. Extraction yield of U exceeded those of the previous work performed with batch system, which resulted in the low extractability of U (about 80%) according to the coexisting element such as Nd and Fe. It was due to the characteristics of multi-stage extractor. On the other hand, low extractability of Np was caused by various oxidation states in the nitric acid medium. In the case of Tc, its high extractability may be attributed to the complex formation with Zr and U, which is not well proved yet. All elements extracted with TBP were stripped into aqueous phase more than 99% by 0.01M $HNO_3$. From the results, this process has no problem with respect to in the same step was required, because Np was distributed in the raffinate and U product, respectively.

• 한국생물공학회:학술대회논문집
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• 2001.11a
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• pp.235-236
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• 2001

We developed a DNA probe analytical system with a patterned array of oligonucleotide molecules immobilized on glass surfaces. The detection capability of the system depended mainly on the way the capture probes were attached to the support as wen as the sequence. We optimized major variables to graft DNA molecules onto a glass support and the DNA probe assay was eventually accomplished without purification of the PCR product.

• Journal of the Korean Operations Research and Management Science Society
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• v.41 no.2
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• pp.1-16
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• 2016

Yield management, which originated from the U.S. service industry, uses pricing techniques and information systems to make demand management decisions. Demand uncertainty is an important factor in the area of demand management. A key strategy to reduce the effects of demand uncertainty is substitution. The most generally known type of substitution is inventory-driven substitution, in which consumers substitute an out-of-stock product by buying a similar or other type of product. Another type of substitution is the price-driven substitution, which occurs as a result of price changes. In this research, we consider two market segments that have unique perishable products. We develop yield management optimization models with stochastic demand based on the newsvendor model where inventory-driven and price-driven substitutions are allowed between products in the two market segments. The most significant contribution of this research is that it develops analytical procedures to determine optimal solutions and considers both types of substitution. We also provide detailed theoretical analysis and numerical examples.

• IE interfaces
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• v.1 no.1
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• pp.85-99
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• 1988

High Touch product is characterized by shorter life cycle together with specification/integration of existing function in order to capitalize the rapidly emerging high technology. R & D strategy for a development of High Touch product generally emphasizes two aspects ; Industrial Design (ID) and Ergonomic Design (ED). However, working knowledge on ED of a systematic identification of potential High Touch products is not readily available. The purpose of this study was three-folded : (1) To emphasize the fact that greater efforts should be geared to ED in High Touch design ; (2) To develop an ergonomic approach based on analysis of implicit human needs that identifies potential area of High Touch ; (3) To bubble with new and probable High Touch products in home electronics that actually demonstrate the validity of this study.

• Journal of Korea Technology Innovation Society
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• v.2 no.2
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• pp.169-186
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• 1999

This study empirically investigates innovative behaviors of the firm. In so doing, a Probit was employed and estimated. We used the raw data of the "corporate innovation survey"(CIS), which, in consent with OECD efforts, is regularly undertaken by the Science and Technology Policy Institute(SIEPI). The data set includes more than 3400 firms in the manufacturing sector. Three types of innovation, i.e., new product, product improvement and process innovation, are studied, assuming that determinants of innovation are firm′s age. number of employees as the size of firm, ratio of foreign ownership and innovation costs. To investigate the relationship between firm′s innovation behavior and the size, we estimate the Probit including the quadratic term of the firm size. Empirical findings showed that the sign of the quadratic term of the firm size turned out to be negative. It means that the probability of firm's making innovation shows the inversed-U relationship with the firm size. Such an empirical result may have a significant implication for the industrial policy.

• Journal of the Korean Applied Science and Technology
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• v.11 no.1
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• pp.53-60
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• 1994

The Synthesis of azobenzene containing long chain fatty acid and poly vinyl alcohol by esterification reaction($C_{n}-Azo-PVA$) was optimized, starting from P-(P'-hydroxy phenyl azo)-benzoic acid and the product of reaction containing azobenzene chromophores was investigated by ultraviolet spectrophotometery in toluene solvent at room temperature. In addition, UV absorption spectra of Langmmuir Blodggett (LB) film deposited on quartz plate have been measured and the structure of these compounds were ascertained by means of Ultraviolet and FT-IR. Recrystallization of reaction product in the solvent results the experimental yield obtained about 22.27% P-(P'-octadecyloxy phenyl azo)-benzoic acid-poly vinyl alcohol. Long chain azobenzene derivative-poly vinyl alcohols are induced phtoisomerization by u, v, and visible light irradiation. The LB film of azobenzene containing long chain fatty acids($C_{18}-Azo-PVA$) are possible of being applied to functional molecular devices such as photomemory and light switching.

• Transactions of Materials Processing
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• v.9 no.5
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• pp.512-525
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• 2000

Designers are frequently faced with multiple quality issues in injection molded parts. These issues are usually In conflict with each other, and thus tradeoff needs to be made to reach a final compromised solutions. The objective of this study is to develop an automated injection molding design methodology, whereby part defects such as warpage and weld line are optimized. The features of the proposed methodology are as follows: first, Utility Function approach is applied to transform the original multiple objective problem into single objective problem. Second is an implementation of a direct search-based Injection molding optimization procedure with automated consideration of process variation. The Space Reduction Method based on Taguchi's DOE(Design Of Experiment) is used as a general optimization tool in this study. The computational experimental verification of the methodology was partially carried out for a can model of Cavallero Plastics Incorporation, U. S. A. Applied to production, this study will be of immense value to companies in reducing the product development time and enhancing the product quality.