• Title/Summary/Keyword: Type of injury

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Sasa quelpaertensis Nakai ethyl acetate fraction protects the liver against chronic alcohol-induced liver injury and fat accumulation in mice (만성 알코올 유발 마우스 간손상 및 지방 축적에 대한 제주조릿대잎 에틸 아세테이트 분획물의 간 보호 효과)

  • Kim, Areum;Lee, Youngju;Herath, Kalahe Hewage Iresha Nadeeka Madushani;Kim, Hyo Jin;Yang, Jiwon;Kim, Ju-Sung;Jee, Youngheun
    • Korean Journal of Veterinary Research
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    • v.60 no.4
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    • pp.215-223
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    • 2020
  • Sasa (S.) quelpaertensis Nakai (Korean name, Jeju-Joritdae), which has anti-oxidative and anti-inflammatory activities, is a type of bamboo grass distributed widely in Jeju Island, Korea. S. quelpaertensis leaves are used for therapeutic purposes in traditional Korean medicine. This study examined the hepatoprotective effects of the S. quelpaertensis ethyl acetate fraction (SQEA) in a mouse model to mimic alcoholic liver damage. The mice were administered orally with 30% alcohol (5 g/kg) once per day with or without SQEA treatments (100 and 200 mg/kg) for 14 days consecutively. Alcohol consumption increased the serum alcohol content and histopathological changes but reduced the liver weight. Moreover, the livers of the alcohol group exhibited the accumulation of malondialdehyde and cytochrome P450 2E1 (CYP2E1), and lipid droplet coating protein perilipin-2. On the other hand, SQEA dose-dependently attenuated the alcohol-induced serum ethanol content and liver histopathological changes but increased the liver weight. Moreover, SQEA attenuated the level of CYP2E1 and inhibited alcohol-induced lipogenesis in the liver via decreased perilipin-2 expression. These results suggest that SQEA can provide a potent way to reduce the liver damage caused by alcohol consumption.

Effects of Capillary Water Interruption Layer on the Growth of Zoysiagrasses and Cool-season Turfgrasses in Reclaimed Land (염해지에서 모세관수 차단층 설치 유무에 따른 한국잔디 및 한지형 잔디류의 생육)

  • Kim, Jun-Beom;Yang, Geun-Mo;Choi, Joon-Soo
    • Asian Journal of Turfgrass Science
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    • v.23 no.1
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    • pp.35-44
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    • 2009
  • This study was carried out to examine the growth performance of 4 species of cool-season grasses and 4 species of zoysiagrasses under salt injury in Seo-san reclaimed area. Grasses were grown on the plots with capillary water interruption layer (WCWIL) and without capillary water interruption layer (WOCWIL) soil systems. Cool-season grass and seeding-type zoysiagrass plots were seeded on 6 Jun, 2006. Vegetative zoysiagrass 'Junggi' was established by sprigging and 'Senock' and 'Millock' were plugged. Electric conductivities of irrigation water (ECw) ranged from 0.28 to $3.3\;dS{\cdot}m^{-1}$. Electric conductivities (ECe) of the soil with capillary water interruption layer and without capillary water interruption layer ranged from 0.55 to $9.4\;dS{\cdot}m^{-1}$ and from 1.84 to $9.4\;dS{\cdot}m^{-1}$ respectively. Leaf color, turf quality, coverage rates, and growth rates were rated visually for 2 years. Zoysiagrass 'Junggi', creeping bentgrass, zoysiagrass 'Senock' and 'Millock' showed acceptable growth at salty fairway condition, while Kentucky bluegrass, perennial ryegrass, Kentucky bluegrass mixed with perennial ryegrass, and seeded zoysiagrass 'Zenith' showed establishment rates below 70%. These results will be useful when choosing turf grass species and cultivars for the golf courses in reclaimed land area.

Development and Effectiveness Evaluation of Acupressure Bed with Variable Type Bogie (변동형 대차 구동방식의 지압 침대 개발 및 유효성 평가)

  • Heo, Sung-Phil;Park, Se-Jin;Ahn, Do-Hyun
    • Journal of Korea Society of Industrial Information Systems
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    • v.25 no.6
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    • pp.47-54
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    • 2020
  • The acupressure is a treatment that applies pressure to certain parts of the body and has been mainly used for pain relief in the field of oriental medicine. However, the treatment effect is often different depending on the practitioner's ability, experience, and physical strength, so standardized acupressure is needed. In this regard, the equipment is being released, but this is mainly a rolling massage method, which reduces energy concentration and poses a risk of injury. Therefore, in this study, a device that provides vertical acupressure based on variable bogie (wheel truck) was implemented. As a result of experimenting with load and body pressure distribution and desirability to validate the device's bearing pressure, the acupressure rod held up to 150kg, the body pressure ratio was measured lower than the body pressure ratio of the comparison item in section 0%

The Effect of Using Standing Step Condition on Biomechanical Variables during Jab in Boxing (복싱 잽(jab) 동작 시 제자리 스텝의 사용이 운동역학적 변인에 미치는 영향)

  • Lee, Seong-Yeol;Kwon, Moon-Seok
    • Journal of the Korean Applied Science and Technology
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    • v.37 no.2
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    • pp.232-240
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    • 2020
  • The purpose of this study was to analyze the effect of using standing step condition on biomechanical variables during jab in boxing. For this purpose, eight orthodox type college boxers(age = 20.38±0.52 yrs, height = 172.38±5.80 cm, body mass = 63.45±8.56 kg, career = 6.00±1.07 yrs) who without injury to the musculoskeletal system participated in the experiment over the last year. In order to verify the effect of biomechanical variables using standing step during jab in boxing, the paired t-test (α = .05) statistical method was used. First, W.S(with-step) showed a greater impact force than N.S(non-step), and muscle activity was analyzed to be low. Second, it was analyzed that the pelvis and foot segments move faster because W.S affects the velocity of the anterior segment of the human body. Third, the rotational movement of the pelvis was faster in W.S. Fourth, W.S was analyzed to have greater ground reaction force in the anterior caused by the right and left foot than N.S. Through this, it was found that the use of the standing step during jab increases the ground reaction force the velocity and rotational movement of the human segment. Therefore, it was confirmed that it allowed a faster and more agile movement, and thus produces a greater impact force with relatively less muscle activity. Therefore, in order to effectively deliver a greater impact force to the opponent during the jab, it was effectively analyzed to accompany the standing step.

Combining Ability Analysis and Selection Effectiveness for Tolerance to Cold-Induced Sterility in Rice (벼 장해형 내냉성의 조합능력검정과 선발효과)

  • Huhn Pal, Moon;J. Neil, Rutger
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.33 no.4
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    • pp.412-419
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    • 1988
  • Cold-induced sterility is a problem of rice (Oryza sativa L.) production in temperate regions and high elevation tropics. The present study was conducted to measure combining ability, determine character associations. and to evaluate effectiveness of F$_2$selection for tolerance to this type of cold injury. The F$_1$, F$_2$, F$_3$ and reciprocal backcross F$_1$ populations of a nine-parent diallel were grown at Davis, California. a relatively cool location for rice. Additive genetic variance was predominant but some non -additive genetic variance existed for cold tolerance. Good general combining ability (GCA) was generally associated with the cold tolerant parents, 'M-201', and 'L-201', and poor GCA with the most susceptible parent. 7703008. Sterility was positively correlated with late heading. negatively with mature plant height. and negatively with spikelet number. Of the three agronomic characters, heading date had the greatest influence on sterility. Selection of F$_2$'s in seven crosses involving M-101, the most cold-tolerant parent, was effective for increasing cold tolerance. Realized heritability estimates for cold tolerance averaged 0.53, and observed selection response for cold-induced sterility averaged -9.4 percentage points.

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Development of severity-adjusted length of stay in knee replacement surgery (무릎관절치환술 환자의 중증도 보정 재원일수 모형 개발)

  • Hong, Sung-Ok;Kim, Young-Teak;Choi, Youn-Hee;Park, Jong-Ho;Kang, Sung-Hong
    • Journal of Digital Convergence
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    • v.13 no.2
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    • pp.215-225
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    • 2015
  • This study was conducted to develop a severity-adjusted LOS(Length of Stay) model for knee replacement patients and identify factors that can influence the LOS by using the Korean National Hospital Discharge in-depth Injury Survey data. The comorbidity scoring systems and data-mining methods were used to design a severity-adjusted LOS model which covered 4,102 knee replacement patients. In this study, a decision tree model using CCS comorbidity scoring index was chosen for the final model that produced superior results. Factors such as presence of arthritis, patient sex and admission route etc. influenced patient length of stay. And there was a statistically significant difference between real LOS and adjusted LOS resulted from health-insurance type, bed size, and hospital location. Therefore the policy alternative on excessive medical utilization is needed to reduce variation in length of hospital stay in patients who undergo knee replacement.

Importance awareness and Compliance on Patient Safety for Nurses Working in Operating Rooms (수술실간호사의 수술환자 안전관리에 대한 중요성인지도와 실천이행도)

  • Kim, Joung-Soon;Kim, Ju-Sung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.12
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    • pp.5748-5758
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    • 2011
  • The purpose of this study was to evaluate the perceived patient safety, type of errors related to patient safety, importance awareness and compliance on patient safety for operating room nurses and to identify factors influencing compliance. Data were collected using a structured questionnaire from 191 perioperative nurses. Data were analyzed using descriptive statistics, t-test, paired t-test, ANOVA, Pearson correlation coefficients, and multiple regression. The perceived patient safety score was 6.3 as moderate level. Types of errors were mostly happened in patient injury (39.8%), counts (18.4%) and infection control (17.5%). The level of compliance on patient safety was significantly lower than that of importance awareness (t=18.01, P<.001). Compliance on patient safety showed significantly positive correlations to importance awareness (r=.56, p<.001). Experience of patient safety education, experience of errors in colleague, job position and working experience in hospital explained 13.9% of variance compliance on patient safety(F=8.407, P<.001). In conclusion, Hospital should develop education program related to patient safety, encourage nurses to manage safety protocol and ensure cultivating patient safety culture in the perioperative practice setting.

Correlation between the Fibrillar Pattern in Ultrasonography and Clinical Factors after Achilles Tendon Repair (아킬레스건 봉합 후 초음파에서 보이는 섬유 배열 양상과 임상적 요인과의 관계)

  • Choi, Young Jin;Ahn, Soo-Hyung;Bae, Su-Young
    • Journal of Korean Foot and Ankle Society
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    • v.26 no.3
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    • pp.123-129
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    • 2022
  • Purpose: To evaluate the correlation between the fibrillar pattern of the Achilles tendon on ultrasonography (US) and functional outcomes in patients who underwent open tendon repair after Achilles tendon rupture. Materials and Methods: Data of 44 patients who had been subjected to US at least 6 months after repair, during the period between July 2012 and July 2019 were reviewed. Those with bilateral tendon rupture, re-rupture, open injury, and chronic or insertional rupture, were excluded from the review. We divided them into two groups, the homogenous group (HoP) and the heterogenous group (HeP) based on the fibrillar pattern on US. We also divided the HoP into linear and wavy subgroups, and the HeP into no hypoechoic lesion and hypoechoic lesion subgroups. The rupture type of the Achilles tendon, radiographic factors including US and magnetic resonance images, patient-related, surgical factors, and clinical results at the last visit after repair were assessed retrospectively. Results: The tendon thickness was 11.4±1.7 mm in the HoP, and 14.5±3.0 mm in the HeP (p<0.001). A shredded pattern was observed in 17 cases (65.4%) in the HoP, and in 17 cases (94.4%) in the HeP (p=0.031). The mean value of the number of sutures used was 8.9±3.05 in the HoP and 11.39±1.75 in the HeP (p=0.001). The mean value of the difference in calf circumference was 0.9±0.67 cm in the HoP and 1.36±0.71 cm in the HeP (p=0.037). There were no statistically significant differences in the fibrillar patterns and patient-related factors. Conclusion: The fibrillar pattern observed after repair was correlated with the functional outcome and showed a significant relationship with the rupture pattern and the number of sutures used. Therefore, we suggest a careful individualized postoperative rehabilitation protocol to maximize functional outcomes by referring to the fibrillar pattern in US, especially in shredded ruptures.

Early Results of the Heart Transplantation for End Stage Heart Failure (말기 심부전증 환자에 대한 심장이식술의 조기 성적)

  • 노준량;원태희
    • Journal of Chest Surgery
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    • v.30 no.9
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    • pp.876-884
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    • 1997
  • Fourteen patients underwent orthotopic heart transplantation between March 1994 and May 1996 in Seoul National University Hospital. There were 9 male and 5 female patients, and the mean age was 40.8 $\pm$ 12.4 years ranged from 12 to 56 years. All patient were in NYHA Fc III or IV preoperatively. The underlying heart diseases were dilated cardiomyopathy in 11 and restrictive cardiomyopathy in 3. The mean age of donors was 24.9$\pm$ 10.2 years and the causes of the brain death were head trauma by traffic accidents in 8, subarachnoid hemorrhage in 2, 1 asphyxia, 1 fall down injury, 1 brain tumo , and 1 drowning, respectively The blood type was identical in 11, compatible in 2, and incompatible in 1 patient. The direct bicaval anastomosis technique was used in 11 cases, and standard right atrial anastomosis was done in the remaining 3 cases. The graft ischemic time was 158$\pm$44 minutes ranged 94 to 220 minutes. There were two hospital deaths(14.3%). The causes of deaths were 1 right ventricular failure followed by suspected cyclosporine induced hemolytic uremic syndrome and rejection, and 1 delayed massive bleeding, probably from rupture of the anastomotic pseudoaneurysm, respectively. The follow-up duration was 16$\pm$9 months(3 to 28 months). There was one late death(8.3%). All the other patients were in NYHA Fc I except one patient who was in hospital because of the acute rejection. The actuarial survival rates including hospital deaths were 93.7% at 1 month, 86.9% at 6 months, and 77$\pm$12% at 2 years. Conclusively, heart transplantation is the good strategy for the management of end stage heart disease with acceptable operative mortality and early follow-up results.

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Anti-obesity Effects of Ginsenoside Rd via AMPK and PPAR Gamma (진세노사이드 Rd의 AMPK 및 PPAR 감마의 신호전달경로를 통한 항비만효과)

  • Kim, Myung-Sunny;Lee, Myoung-Soo;Kim, Soon-Hee;Kim, Sung-Hee;Kim, Hyun-Jin;Sung, Mi-Jeong;Kim, Hye-Young;Kwon, Dae-Young;Hwang, Jin-Taek
    • KSBB Journal
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    • v.22 no.5
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    • pp.341-344
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    • 2007
  • Obesity is a major obstacle for human health, which induces various diseases such as cardiac injury and type 2 diabetes. Ginsenosides, active components of ginseng extract, exert various physiological effects. However, There are still no evidence for their anti obesity effects. In this study, we investigated the effects of ginsenoside Rd on adipocyte differentiation in 3T3-L1 cells. Our data show that ginsenoside Rd (80 uM) was effective in adipocyte differentiation inhibition. These inhibitory effects of ginsenosides on adipocyte differentiation were accompanied by PPAR gamma inhibition in rosiglitazone-treated cells. We also tested whether AMP-activated protein kinase (AMPK) activation was involved in the effects of these ginsenosides. AMPK is a master target for obesity, ginsenoside Rd significantly activated AMPK. Taken together, these results suggest that the anti obesity effects of ginsenoside Rd involve the AMPK signaling pathway and PPAR-gamma inhibition.