• Journal of Korean Physical Therapy Science
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• v.9 no.2
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• pp.37-48
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• 2002

The purpose of this study is to improve the effect of Lumbar extensor exercise program and develop the Lumbar extensor exercise program which will be suitable to the patients characteristics. In this study the experimental group was made up of 38 subjects. They are the patients with low back pain using the Lumbar extension exercise program in C hospital. The lumbar extension exercise program was given two times a week for 8 weeks. The results were estimated by Lumbar extensor strength by diagnosis agent. The results were measured three times, one time pre-treatment and two times post-treatment at 4weeks and 8weeks by lumbar extensor curve angle(0, 12, 24, 36, 48, 60, 72). The results were compared at pre-test 4weeks and 8weeks. The muscle strength measured at both 4weeks and 8weeks with the greater strength was shown at 4weeks. The muscle strength of patients with M.strain, Laminectomy and HNP was increased at all angles except for patients with stenosis. The results of this study indicated that diagnosis influenced the muscle strength in Lumbar extensor exercise program.

• Journal of the Korean Society of Food Science and Nutrition
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• v.23 no.2
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• pp.181-186
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• 1994

The present study was undertaken to clarify the effect of Puffer fish skin extract (PF) on the hepatic alcohol metabolism in rats. It was observed that alcohol concentration in blood had been markedly decreased by the pretreatment of PF for two weeks. Activities of alcohol dehydrogenase (ADH) and microsomal ethanol-oxidizing system (MEOS) were significantly incrased (more than 20% of control) by pretreatment of PF for two weeks and acute alcohol intoxication (5 g/kg) on final day. When rats were fed with subacute toxic state by alcohol (25v/v % , once a day for six weeks), activities of ADH and MEOS were significantly increased by additional treatments of PF for final two weeks. But the catalase activity was not affected by any of both case. And also activities of ADH and MEOS in vitro were not changed . These results suggest that PF treatemnt prompted the recovery from alcohol intoxication.

• Restorative Dentistry and Endodontics
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• v.14 no.1
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• pp.7-24
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• 1989

The purpose of the study was to evaluate the cytotoxic effects of polycarboxylate cements and zinc phosphate cements in vitro. Human fibroblasts were cultured in ${\alpha}$-MEM, and each cement was manually mixed and filled in glass ring cylinder (8${\times}$8mm in diameter, in height.) Cement filled cylinders were placed in the center of the dish (35mm in diameter) containing 3ml of ${\alpha}$-MEM. Millipore filters to simulate dentinal barrier were also placed between the cylinder and the dish, then stored in 5% $CO_2$ containing chamber for 1 and 2 weeks at the temperature of $36.6^{\circ}C$. The results of the experiments were analyzed by counting the cells in the period of one week and two weeks respectively, and were assessed by calculating the cell multiplication rate and the relative growth rate. The experimental groups and the control group were compared. The results of the study were summarized as follows. 1. Durelone brand of the polycarboxylate cements showed marked cytotoxicity after one week, but after two weeks the toxicity decreased remarkably. Poly-F brand exhibited moderate cytotoxicity after one week, but after two weeks the toxicity slightly decreased. HY-BOND brand was weakly cytotoxic after one week, but after two weeks the toxicity became significant. 2. The cytotoxicity of the zinc phosphate cements was negligible after one week, but after two weeks Lee Smith brand revealed considerable cytotoxicity. 3. In general, the zinc phosphate cements were less cytotoxic than the polycarboxylate cements.

• Journal of Chest Surgery
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• v.22 no.6
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• pp.914-920
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• 1989

Bleomycin and cyclophosphamide are widely used and effective anti-cancer agents for treatment of various forms of cancer. Bleomycin has no myelotoxicity, but because of potential risk of pulmonary complications including interstitial pneumonitis and idiopathic interstitial pulmonary fibrosis, it has been limited in use. Some investigator has also suggested that cyclophosphamide can induce pulmonary toxicity like bleomycin. Recently, The combination chemotherapy including bleomycin and cyclophosphamide has been adopted effectively in some types of cancer. But there are no available literatures for synergistic effect of pulmonary toxicity in combination chemotherapy including these two drugs. We tried this study to observe synergism of pulmonary toxicity using these two drugs in rats. The animals were divided into five groups: group 1 received intra-peritoneal injection of saline, group 2-a received only bleomycin 0.1 mg [0.4 mg/kg] by intra-peritoneal injection twice a week, group 2-b received only bleomycin 0.5 mg [2 mg/kg] by intra-peritoneal injection twice a week, group 3-a received bleomycin 0.1 mg [0.4 mg/kg] twice a week +cyclophosphamide 5 mg [20 mg/kg] two weeks interval by intra-peritoneal injection, group 3-b received bleomycin 0.5 mg [2 mg/kg] twice a week + cyclophosphamide 5 mg[20 mg/kg] two weeks interval by intra-peritoneal injection. The animals were sacrificed at 2 and 4 weeks later. Lung tissues were obtained and observed by light microscope. The results are as follows: 1. The pathologic findings of group 1 were normal without change. 2. There was no difference between group 2-a and group 3-a at 2 weeks later, group 3-a, however, revealed more severe change in lung tissue at 4 weeks later compared with group 2-a. 3. In group 3-b there was more severe pulmonary injury compared with group 2-b at 2 and 4 weeks later. We conclude that the combined administration of bleomycin and cyclophosphamide induce more severe pulmonary toxic effect than bleomycin administration alone and the combination chemotherapy including these two drugs will be require special attention to selection of the dose of each drug.

• Journal of Haehwa Medicine
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• v.15 no.1
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• pp.87-95
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• 2006

Objective : We suggested the clinical effect of Rainbow therapy on Bell's palsy. Methods : 20 Bell's palsy patients were divided into two groups. One group(A group) was treated by acupunture and the other group(B group) was treated by acupunture and Rainbow therapy. The effect of these treatments was evaluated by Yanagihara's unweighted grading system and House-Brackmann grading system. Results and Conclusions : In Yanagihara's unweighted grading system After 1 week and 2weeks treatment, group B marked more higher than group A in treatment outcome. We discovered that it is significant differences between two groups. After 3 weeks treatment, group B marked more higher than group A in treatment outcome but it is not significant differences between two groups. In House-Brackmann's facial nerve grading system, After 1 week treatment, group B marked more higher than group A in treatment outcome. We discovered that it is significant differences between two groups. After 2 weeks and 3 weeks treatment, group A marked more higher than group A in treatment outcome but it is not significant differences between two groups.

• Journal of muscle and joint health
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• v.29 no.2
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• pp.133-140
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• 2022

Purpose: This study was to examine the effects of auricular acupressure on competitive state anxiety and the accuracy of breaking in taekwondo players. Methods: This study was a quasi-experimental study with a time-series design. Twenty-two taekwondo breaking players were assigned to the control group for the first two weeks and then assigned to the experimental group for the next two weeks. Anxiety was measured by the revised Competitive State Anxiety Inventory-2 and the accuracy of breaking was measured as a percentage of breaking the wooden board. Results: Auricular acupressure for two weeks significantly increased the accuracy of breaking from 80.83±7.99% to 90.92±7.57% (t=7.74, p<.001). Auricular acupressure for two weeks significantly increased anxiety from 35.66±10.36 to 50.64±7.45 (t=4.38, p<.001). Among three subtypes of competitive state anxiety, somatic anxiety was increased from 12.48±4.97 to 22.95±4.54 (t=2.09, p=.011). Cognitive anxiety was significantly increased from 10.11±3.96 to 14.68±3.89 (t=5.37, p<.001) but self-confidence was not changed. Conclusion: The results of this study showed that auricular acupressure was effective in increasing the accuracy of breaking in taekwondo players.

• Journal of the Ergonomics Society of Korea
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• v.32 no.3
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• pp.267-271
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• 2013

Objective: The purpose of this study is to examine the test-retest reliability of paper-pencil test for investigating population stereotype of burner-control linkages of four-stove gas ranges. Background: Much of the research on gas-range stereotype strength has been performed using the paper-pencil test. While the use of the paper-pencil tests has the advantage of collecting data in a large group of subjects against reasonable costs, concerns regarding the reliability of the paper-pencil test has also been stated. Method: Three paper-pencil tests classified by intervals of test-retest were performed, in which eight types of burner-control arrangements were investigated. Sixty eight subjects were test-retested within two weeks, 85 subjects were test-retested within four weeks and 58 subjects were test-retested three times in series with interval of two and four weeks. Results: Chi-square test showed that three intervals of test-retest including two, four and two & four weeks have not statistically significant effect on subjects' responses irrespective of eight types of burner-control linkages dealt with in this study(p>0.10). Concordance rates of subjects' responses ranged between 73.5% and 100.0% for two-week test-retest, between 67.1% and 97.6% for four-week test-retest, and between 65.5% and 100.0% for two- and four-week serial test-retest. The concordance rates were linearly correlated with proportion of subjects' responses for stereotypes of burnercontrol linkages. Conclusion: It is concluded that the paper-pencil tests for investigating gas range relevant stereotypes could reproduce reliable results compared to baseline test within interval of four weeks. Application: The results of this study would be useful as an ergonomic guideline when designing the paper-pencil tests for stereotype relevant studies.

• The Journal of Korean Physical Therapy
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• v.19 no.6
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• pp.31-36
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• 2007

Purpose: This study compared the thigh circumference and Lysholm scale of a stable and unstable exercise group of patients who had undergone an anterior cruciate ligament reconstruction (ACL reconstruction). Methods: The subjects were patients more than 4 weeks after their ACL reconstruction and could stand on one leg. The patients were divided into a control group with 9 patients performing closed kinetic chain exercises on a stable floor and an experimental group with 10 patients performing closed kinetic chain exercises en an unstable floor. The degree of muscle atrophy was compared by measuring the circumference of the injured thigh before the exercise program, and 3 weeks and 6 weeks after the exercise program. The Lysholm scale was used to assess the function of the knee joint. Results: There was no significant increase in thigh circumference according to the exercise periods in the two groups. However, there was a statistically significant increase before exercises and 6 weeks after the exercises (p<0.05). There were statistically significant differences in the Lysholm scores between the two groups (p<0.05). Conclusion: There were no statistically significant increase in the two groups, but there was a significant difference between before the exercise program and 6 weeks after the exercise program (p<0.05).

• Journal of Nutrition and Health
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• v.19 no.1
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• pp.66-73
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• 1986

This study was undertaken to investigate the effects of age and of the dietary protein sources & levels on urinary calcium excretion and bone metabolism in the rats. Two experiments were conducted . In experiment U, 6& 20 weeks old rats were fed 8 & 36%, casein & ffish protein diet for 5 weeks . In experiment II, 16& 52 weeks old rats were fed 40 % protein diets, protein sources were casein, fish and gluten. High-protein diet group excreted more caldium in urine than low-protein group. Urinary calcium excretion was affected by the sources of protein ; gluten group excreted more Ca, followed by fish & casein group. Total bone Ca & Ca proportion in ash were higher in 20 weeks old rats than 6 weeks old rats, but 16 & 52 weeks old rats showed no differences. bone composition showed that water proportion was high and ash proportion was low in 6 weeks old rats than in 20 weeks old rats. However, these tendencies were not observed between 16 weeks and 52 weeks old rats. And bone composition was affected by protein sources ; higher ash proportions were noted in one order of casein, fish, and gluten water proportion were lower in one same order.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.32 no.4
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• pp.317-326
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• 2006

Purpose : The aim of this study was to evaluate the effect of recombinant human bone morphogenetic protein-7 (rhBMP-7) injected on the rate of new-bone formation for distraction osteogenesis on dogs. Materials & Methods : Twelve adult dogs were randomly selected into two groups of six dogs on each. Unilateral osteotomies were performed on the body of the mandible and an intraoral distractor was mounted to the mandible on dogs. One group was treated with injection of rhBMP-7 and the other group served as the control. RhBMP-7 was administered on the day of surgery by single injection into the medullary bone at the osteotomy gap. Distraction was performed five days after osteotomy as a rate of 0.5 mm twice per day for 10 days. The animals were then sacrificed at 2, 4, and 8 weeks after completion of the distraction. Two dogs in each group, totaling four dogs, were killed at 2 weeks, 4 weeks, and 8 weeks after completion of distraction, respectively. The lengthened mandibles were harvested and processed for radiographic and histological examinations. In addition, immunohistochemical examination using osteocalcin expression was studied. Results : Radiographs showed accelerated regenerate ossification with maturation of new bone in the rhBMP-7 group comparing with the control group at the 4 weeks of the consolidation. There was no significant difference in the radiographic findings at the 2 weeks and 8 weeks of the consolidation period. Histological findings demonstrated increased bone healing pattern in the rhBMP-7-treated group during all observation period. The expression of osteocalcin immunoreactivity was hardly detected in the normal mandible of dog, but the expression was detected in all experimental rhBMP-7 treated specimens. There were also significant increasing in number of positive immunostaining cells and staining intensity of osteocalcin expression in the rhBMP-7 treated group compared with those of the control group on 2-weeks and 4-weeks. There was a significant decreasing in staining intenstiy of all both two groups on 8 weeks of consolidation period, but significant differences of immunostaining was not seen in two groups. Conclusions : A single injection of rhBMP-7 at the time of osteotomy may stimulate the rate of regenerate ossification and increase callus maturation during distraction osteogenesis. In addition, it may shorten the distraction osteogenesis procedure and decrease the prevalence of complications associated with mandibular distraction osteogenesis.