• Steel and Composite Structures
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• 제23권1호
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• pp.115-130
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• 2017

A new type of moment-resisting bolted connection was developed for use in composite steel- concrete construction to connect composite open section steel beams to concrete filled steel square tubular columns. The connection was made possible using anchored blind bolts along with two through bolts. It was designed to act compositely with the in-situ reinforced concrete slab to achieve an enhanced stiffness and strength. The developed connection was incorporated in the design of a medium rise (five storey) commercial building which was located in low to medium seismicity regions. The lateral load resisting system for the design building consisted of moment resisting frames in two directions. A major full scale test on a sub-assembly of a perimeter moment-resisting frame of the model building was conducted to study the system behaviour incorporating the proposed connection. The behaviour of the proposed connection and its interaction with the floor slab under cyclic loading representing the earthquake events with return periods of 500 years and 2500 years was investigated. The proposed connection was categorized as semi rigid for unbraced frames based on the classification method presented in Eurocode 3. Furthermore, the proposed connection, composite with the floor slab, successfully provided adequate lateral load resistance for the model building.

• 대한화학회지
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• 제33권4호
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• pp.388-398
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• 1989

기체 감응막전극을 이용하여 수용액 중의 아질산이온을 연속${\cdot}$자동화법으로 정량하는 방법을 개발하였다. 이 방법에서 최종검출기로 쓴 이온선택성 전극은 관형 PVC막 pH 전극이었다. 장치계의 최적조건에서 구한 아질산이온 표준시료에 대한 전극의 감응기울기는 63.5mV/decade 이었으며, 직선감응 범위는 $2.5{\times}10^{-4}\; M{\sim}7.5 {\times} $10^{-2}$M 이었고, 검출한계는 $8.0{\times} 10^{-5}$M이었다. 이 방법은 다른 정량법보다 산성기체종의 방해를 적게 받을 뿐만 아니라 정량에 필요한 시간도 훨씬 단축할 수 있었다.

• Advances in Computational Design
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• 제8권2호
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• pp.147-177
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• 2023

Elliptical concrete-filled steel tubular (CFST) column is widely used in modern structures for both aesthetical appeal and structural performance benefits. The ultimate axial load is a critical factor for designing the elliptical CFST short columns. However, there are complications of geometric and material interactions, which make a difficulty in determining a simple model for predicting the ultimate axial load of elliptical CFST short columns. This study aims to propose an efficient adaptive neuro-fuzzy inference system (ANFIS) model for predicting the ultimate axial load of elliptical CFST short columns. In the proposed method, the ANFIS model is used to establish a relationship between the ultimate axial load and geometric and material properties of elliptical CFST short columns. Accordingly, a total of 188 experimental and simulation datasets of elliptical CFST short columns are used to develop the ANFIS models. The performance of the proposed ANFIS model is compared with that of existing design formulas. The results show that the proposed ANFIS model is more accurate than existing empirical and theoretical formulas. Finally, an explicit formula and a Graphical User Interface (GUI) tool are developed to apply the proposed ANFIS model for practical use.

• The Korean Journal of Physiology
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• 제29권1호
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• pp.69-80
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• 1995

Renal proximal tubular hypertrophy and hyperfunction are known to be early manifestations of experimental and human diabetes. As the hypertrophy and hyperfunction have been suggested to be central components in the progression to renal failure, an understanding of their underlying causes is potentially important for the development of therapy. A primary rabbit kidney proximal tubule cell culture system was utilized to evaluate the possibility that the renal proximal tubular hypertrophy and hyperfunction observed in vivo in diabetes mellitus, can be attributed to effects of elevated glucose levels on membrane transport systems. Primary cultures of rabbit proximal tubules, which achieved confluence at 10 days, exhibited brush-border characteristics typical of proximal tubular cells. Northern analysis indicated $2.2{\sim}2.3$ and 2.0 kb Na/glucose cotransporter RNA species appeared in fresh and cultured proximal tubule cells after confluence, repectively. The cultured cells showed reduced Na/glucose cotransporter activity compared to fresh proximal tubules. Primary cultured proximal tubule cells incubated in medium containing 20 mM glucose have reduced ${\alpha}-MG$ transport compared to cells grown in 5 mM glucose. In the proximal tubule cultures incubated in medium containing 5 mM or 20 mM glucose, phlorizin at 0.5 mM inhibited 0.5 mM ${\alpha}-MG$ uptake by 84.35% or 91.85%, respectively. The uptake of 0.5 mM ${\alpha}-MG$ was similarly inhibited by 0.1 mM ouabain (41.97% or 48.03% inhibition was observed, respectively). In addition, ${\alpha}-MG$ uptake was inhibited to a greater extent when $Na^{+}$ was omitted from the uptake buffer (81.86% or 86.73% inhibition was observed, respectively). In cell homogenates derived from the primary cells grown in 5 mM glucose medium, the specific activity of the Na/K-ATPase $(6.17{\pm}1.27\;{\mu}mole\;Pi/mg\;protein/hr)$ was 1.56 fold lower than the values in cell homogenates treated with 360 mg/dl D-glucose, 20 mM $(9.67{\pm}1.22\;{\mu}mole\;Pi/mg\;protein/hr)$. Total $Rb^{+}$ uptake occurred at a significantly higher rate (1.60 fold increase) in primary cultured rabbit kidney proximal tubule cell monolayers incubated in 20 mM glucose medium $(10.48{\pm}2.45\;nM/mg\;protein/min)$ as compared with parallel cultures in 5 mM glucose medium. $Rb^{+}$ uptake rate in 5 mM glucose medium was reduced by 28% when the cultures were incubated with 1 mM ouabain. The increase of the $Rb^{+}$ uptake by rabbit kidney proximal tubule cells in 20 mM glucose could be attributed primarily to an increase in the rate of ouabain-sensitive $Rb^{+}$ uptake $(5\;mM\;to\;20\;mM;\;4.68{\pm}0.85\;to\;8.38{\pm}1.37\;nM/mg\;protein/min)$. In conclusion, the activity of the renal proximal tubular Na,K-ATPase is elevated in high glucose concentration. In contrast, the activity of the Nafglucose cotransport system is inhibited.

• 한국철도학회논문집
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• 제2권1호
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• pp.56-66
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• 1999

This purpose of this paper is to perform the readhesion control algorithm of the urban railway traction. A study on readhesion control algorithm is done for the adhesion system. This system has all characteristics of the voltage source converter by a process ability to regenerate power. The traction motor is controlled by IGBT inverter. The test equipment composes traction motor, torque-meter, clutch, and a tubular type of interia mass.

• 한국의류학회지
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• 제36권8호
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• pp.828-836
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• 2012

This study provided the data for the planning of knit apparel by analyzing structural effects of intarsia and jacquard knit on mechanical properties, subjective hand measurements, and preference. Intarsia and 7 types of color jacquard (floating jacquard, normal jacquard, bird's eye jacquard, tubular jacquard, ladder's back jacquard, blister jacquard, and transfer jacquard) were used. The samples (with a gauge of 14) were knitted using 100% wool 2/48's yarn by a Shima Seiki SIG computer knitting machine. Mechanical properties and hand values were measured by a KES-FB system. Subjective hand and favorable images were surveyed based on women in their 20s and 30s. The data were analyzed by a factor analysis, ANOVA and correlation analysis using SPSS 12.0. The subjective hand of intarsia and jacquard knits was categorized into 'thermofeeling', 'weight/flexibility', and 'durability'. The results of the favorable image survey for F/W outer knitwear showed that tubular jacquard was most favorable; however, the transfer jacquard was least favorable. Among the three factors that explain the subjective hand, thermofeeling had a strong influence on the favorable image of consumers. Bird's eye jacquard and tubular jacquard turned out to be most suitable for suits, intarsia and floating jacquard were suitable for cardigans and sweaters, ladder's back jacquard was suitable for hats or mufflers, and transfer jacquard was suitable for home fashion rather than garments.

• 한국강구조학회 논문집
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• 제13권3호
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• pp.313-325
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• 2001

14TON 밴 형식의 트럭에 대응할 수 있는 튜브형 트라이빔 교량난감을 제안하였다. 이 교량난간은 합성형 지주에 연결된 튜브형 트라이빔과 철재 가드빔으로 구성되어 있는데, 튜브형 트라이빔은 다양한 범퍼 높이를 갖는 차량에 대응할 수 있고 기존의 교량 난간에 비해서 교량난간의 시종점부와 가드레일 사이를 보다 완벽하게연결할 수 있는 장점이 있다. 가드레일 지주로 사용되는 것과 동일한크기의 철재 파이프에 콘크리트를 충전한 합성형지주가 단순히 철재 파이프의 크기를 키운 것보다 강성 및 극한강도를 증대시키는데 효율적임을 확인하였다. 개발된 시스템에 대하여 $14Ton-80km/h-15Y^{\circ}$의 충돌조건으로 실차 충돌실험을 실시하였는데 NCHRP Report 350의 실험레벨 4의 평가항목을 모두 만족하였다. 컴퓨터 시뮬레이션을 통하여 이 시스템이 국내의 S2 등급으로 분류될 수 있음을 보여주었다.

• The Korean Journal of Physiology and Pharmacology
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• 제2권1호
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• pp.69-76
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• 1998

Cis-diamminedichloroplatinum II (cisplatin), an effective antitumor agent, induces acute renal failure by unknown mechanisms. To investigate direct toxic effects of cisplatin in the renal proximal tubular transport system, OK cell line was selected as a cell model and $Na^+/H^+$ antiport activity was evaluated during a course of cisplatin treatment. The cells grown to confluence were treated with cisplatin for 1 hour, washed, and incubated for up to 48 hours. At appropriate intervals, cells were examined for $Na^+/H^+$ antiport activity by measuring the recovery of intracellular pH (pHi) after acid loading. Cisplatin of less than 50 ${\mu}M$ induced no significant changes in cell viability in 24 hours, but it decreased the viability markedly after 48 hours. In cells exposed to 50 ${\mu}M$ cisplatin for 24 hours, the $Na^+-dependent$ pHi recovery (i.e., $Na^+/H^+$ antiport) was drastically inhibited with no changes in the $Na^+-independent$ recovery. Kinetic analysis of the $Na^+-dependent$ pHi recovery indicated that the Vmax was reduced, but the apparent Km was not altered. The cellular $Na^+$ and $K^+$ contents determined immediately before the transport measurement appeared to be similar in the control and cisplatin group, thus, the driving force for $Na^+-coupled$ transport was not different. These results indicate that cisplatin exposure impairs the $Na^+/H^+$ antiport capacity in OK cells. It is, therefore, possible that in patients treated with a high dose of cisplatin, proximal tubular mechanism for proton secretion (hence $HCO_3^-$ reabsorption) could be attenuated, leading to a metabolic acidosis (proximal renal tubular acidosis).

• Childhood Kidney Diseases
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• 제16권2호
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• pp.126-131
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• 2012

쇠그렌 증후군은 주로 침샘과 눈물샘을 침범하는 자가 면역 질환으로, 폐나 간, 콩팥, 췌장, 피부, 신경계 등의 다른 장기 역시 침범하여 임상 증상을 나타내기도 한다. 성인의 경우 이런 다른 장기와 관련된 증상은 드물지 않으나 소아에서는 매우 드물다고 알려져 있다. 특히 콩팥을 침범한 쇠그렌 증후군은 성인의 경우 비교적 흔하지만 소아는 매우 드문데, 이에 본 저자들은 신성 요붕증과 신세뇨관 산증을 주 증상으로 진단한 소아의 일차성 쇠그렌 증후군 1례를 경험하였기에 보고한다.

• Korean Membrane Journal
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• 제10권1호
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• pp.26-32
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• 2008

The Gongji stream water of Chuncheon city was filtrated by 2 kinds of tubular alumina ceramic MF membranes with periodic $N_2$-back-flushing. $N_2$-back-flushing time (BT) was changed in $0{\sim}50$ sec at fixed filtration time (FT), or back-flushing period, of 4 min for NCMT-5231 membrane ($0.05\;{\mu}m$). Then, FT was changed in $0{\sim}32$ min at fixed BT of 40 sec for NCMT-7231 $0.1{\mu}m)$). In the viewpoints of total permeate volume ($V_T$), dimensionless permeate flux ($J/J_0$) and resistance of membrane fouling ($R_f$), the optimal $N_2$-BT was 50 sec, which was the longest BT, at 4 min FT for NCMT-5231. It means the longest BT was the most effective to minimize the membrane fouling, and we could acquire the most $V_T$. But the optimal FT for NCMT-7231 was 16 min in the viewpoint of $V_T$, and was 8 min in the viewpoints of $J/J_0$ and $R_f$ at fixed BT of 40 sec. The rejection rates were excellent as $80.6{\sim}96.6\;%$ for turbidity, $35.2{\sim}58.4%$ for $NH_3$-N, $16.3{\sim}45.2%$ for T-P and $16.3{\sim}45.2%$ for $COD_{Mn}$. However, the rejection rate of T-N was very low as $2.7{\sim}13.4%$ and it of TDS below 6.1%.