• Title/Summary/Keyword: Tropane

Search Result 49, Processing Time 0.035 seconds

Studies on the Determination of Hyoscine-N-butylbromide by ORD and CD(I) (ORD 및 CD에 의한 Tropane Alkaloid의 정량에 관한연구(I) - Hyoscine-N-butylbromide의 정량)

  • 백남호;박만기;염정록;김예숙
    • YAKHAK HOEJI
    • /
    • v.23 no.3_4
    • /
    • pp.129-132
    • /
    • 1979

  • The ORD and CD for hyoscine-N-butylbromide present curves of negative Cotton effect in 190-250nm region. The values of .alpha./sub 232/ .alpha./sub 208/, vertical bar .alpha./sub 232/ vertical bar + vertical bar .alpha./sub 208/ and .theta./sub 221.5/ have linearities in the range of lower concentration (hyoscine-N-butylbromide 0.01-0.1w/v%). It is possible to determine the optical purity of hyoseine-N-butylbromide by using these linearities. This experiment is extremely simple and less time-consuming than other methods for estimating optical purity.

  • PDF

Gas-liquid Chromatographic Analysis of Some Tropane Alkaloids

  • Paik, Nam-Ho;Im, Yong-Bin;Park, Man-Ki
    • YAKHAK HOEJI
    • /
    • v.20 no.3
    • /
    • pp.125-129
    • /
    • 1976

  • The aim of this investigation was to develop a quantitative gas-liquid chromatographic method of analysis forhyosyamine and scopolamine, and to apply this method to the analysis of preparations. The trimethylsily(TMS) derivatives of the alkaloids were found to be far superior to the nonsilylating compounds in charomatagrams. Bis(trimethylsilyl) acetamide(BSA) was evaluated and found to be a good reagent for silyation of the alkaloids. The optimum derivatization conditions were heating the alkaloids in a closed tube at $70^{\circ)$ for 30 min with a 150 molar excess of BSA to the alkaloids were found to be alkaloids. Calibration curves for the two alkaloids were alkaloid. The standard deviations were 1.1% for hyoscyamine and 1.5% for scopolamine. The minimum detectable amount using the hydrogen flame ionization edtector was determined to be 2$\times$10$^{-11}$ moles of each alkaloid injected.

  • PDF

Bioceramic Effects to Enhance Secondary Metabolites Production in Tissue Culture of Some Medicinal Plants

  • Kim, Yu-Jeong;Hwang, Baik;Ahn, Jun-Cheul
    • Korean Journal of Medicinal Crop Science
    • /
    • v.12 no.2
    • /
    • pp.118-122
    • /
    • 2004

  • We have investigated that a couple of soft ferrite ceramic powders having a spinal structure have shown the effect on growth and secondary metabolites production of some medicinal plants cultured in vitro. The addition of the ceramic powders as bare state to culture medium has stimulated the growth of Achyranthes japonica callus and plantlet, adventitious root of Hyoscyamus niger and Platycodon grandiflorum hairy root about 65, 75, 150 and 50%, respectively. Whereas Centella asiatica callus and plantlet, Scopolia parviflora hairy root, and Hyoscyamus albus adventitious root were not affected markedly. Moreover, the ceramic powder has enhanced the growth of H. niger adventitious roots even under conditions of irradiating alone without any direct contact between ceramic powder and media. Based on growth stimulation effect, the ceramic powders have enhanced the gross production of tropane alkaloid in H. niger adventitious root, and polyacetylene in P. grandiflorum hairy root about 35 and 30%, respectively.

  • PDF KSCI